The contribution of tsunami evacuation analysis to evacuation planning in Chile: Applying a multi-perspective research design

Research on evacuation behavior in natural disasters provides a valuable contribution in the development of effective short- and long-term strategies in disaster risk management (DRM). Many studies address evacuation simulation utilizing mathematical modeling approaches or GIS-based simulation. In this contribution, we perform a detailed analysis of an entire evacuation process from the decision to evacuate right up to the arrival at a safe zone. We apply a progressive research design in the community of Talcahuano, Chile by means of linking a social science approach, deploying standardized questionnaires for the tsunami affected population, and a GIS-based simulation. The questionnaire analyzes evacuation behavior in both an event-based historical scenario and a hypothetical future scenario. Results reveal three critical issues: evacuation time, distance to the evacuation zone, and method of transportation. In particular, the excessive use of cars has resulted in congestion of street sections in past evacuations, and will most probably also pose a problem in a future evacuation event. As evacuation by foot is generally recommended by DRM, the results are extended by a GIS-based modeling simulating evacuation by foot. Combining the findings of both approaches allows for added value, providing more comprehensive insights into evacuation planning. Future research may take advantage of this multi-perspective research design, and integrate social science findings in a more detailed manner. Making use of invaluable local knowledge and past experience of the affected population in evacuation planning is likely to help decrease the magnitude of a disaster, and, ultimately, save lives

Transdisciplinary climate change education in the research-education cooperation k.i.d.Z.21

Die Forschungs-Bildungs-Kooperation k.i.d.Z.21 fördert die Zusammenarbeit zwischen Schülerinnen und Schülern und (wissenschaftlichen) Expertinnen und Experten in (außer-)schulischen Lernsettings zum Thema Klimawandel. k.i.d.Z.21 trägt zur Stärkung von Faktoren bei, die klimafreundliches Handeln fördern, und begünstigt gegenseitiges Lernen. Dies wird anhand quantitativer und qualitativer Forschungsergebnisse dargelegt. (DIPF/Orig.)The research-education cooperation k.i.d.Z.21 promotes cooperation between students and (scientific) experts in (extra-)curricular learning settings on the topic of climate change. k.i.d.Z.21 contributes to strengthening factors that promote climate-friendly action and fosters mutual learning. It is presented based on quantitative and qualitative research results. (DIPF/Orig.

Day care study showed no differences in long-term symptoms in children who were and were not infected during COVID-19 outbreaks

Peer Reviewe

SARS-CoV-2 Transmissibility Within Day Care Centers—Study Protocol of a Prospective Analysis of Outbreaks in Germany

Introduction: Until today, the role of children in the transmission dynamics of SARS-CoV-2 and the development of the COVID-19 pandemic seems to be dynamic and is not finally resolved. The primary aim of this study is to investigate the transmission dynamics of SARS-CoV-2 in child day care centers and connected households as well as transmission-related indicators and clinical symptoms among children and adults. Methods and Analysis: COALA (“Corona outbreak-related examinations in day care centers”) is a day care center- and household-based study with a case-ascertained study design. Based on day care centers with at least one reported case of SARS-CoV-2, we include one- to six-year-old children and staff of the affected group in the day care center as well as their respective households. We visit each child's and adult's household. During the home visit we take from each household member a combined mouth and nose swab as well as a saliva sample for analysis of SARS-CoV-2-RNA by real-time reverse transcription polymerase chain reaction (real-time RT-PCR) and a capillary blood sample for a retrospective assessment of an earlier SARS-CoV-2 infection. Furthermore, information on health status, socio-demographics and COVID-19 protective measures are collected via a short telephone interview in the subsequent days. In the following 12 days, household members (or parents for their children) self-collect the same respiratory samples as described above every 3 days and a stool sample for children once. COVID-19 symptoms are documented daily in a symptom diary. Approximately 35 days after testing the index case, every participant who tested positive for SARS-CoV-2 during the study is re-visited at home for another capillary blood sample and a standardized interview. The analysis includes secondary attack rates, by age of primary case, both in the day care center and in households, as well as viral shedding dynamics, including the beginning of shedding relative to symptom onset and viral clearance. Discussion: The results contribute to a better understanding of the epidemiological and virological transmission-related indicators of SARS-CoV-2 among young children, as compared to adults and the interplay between day care and households.Peer Reviewe

Analysis of shared heritability in common disorders of the brain

ience, this issue p. eaap8757 Structured Abstract INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed study of phenotypes with different ages of onset, severity, and presentation poses a considerable challenge. Recently developed heritability methods allow us to accurately measure correlation of genome-wide common variant risk between two phenotypes from pools of different individuals and assess how connected they, or at least their genetic risks, are on the genomic level. We used genome-wide association data for 265,218 patients and 784,643 control participants, as well as 17 phenotypes from a total of 1,191,588 individuals, to quantify the degree of overlap for genetic risk factors of 25 common brain disorders. RATIONALE Over the past century, the classification of brain disorders has evolved to reflect the medical and scientific communities' assessments of the presumed root causes of clinical phenomena such as behavioral change, loss of motor function, or alterations of consciousness. Directly observable phenomena (such as the presence of emboli, protein tangles, or unusual electrical activity patterns) generally define and separate neurological disorders from psychiatric disorders. Understanding the genetic underpinnings and categorical distinctions for brain disorders and related phenotypes may inform the search for their biological mechanisms. RESULTS Common variant risk for psychiatric disorders was shown to correlate significantly, especially among attention deficit hyperactivity disorder (ADHD), bipolar disorder, major depressive disorder (MDD), and schizophrenia. By contrast, neurological disorders appear more distinct from one another and from the psychiatric disorders, except for migraine, which was significantly correlated to ADHD, MDD, and Tourette syndrome. We demonstrate that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine. We also identify significant genetic sharing between disorders and early life cognitive measures (e.g., years of education and college attainment) in the general population, demonstrating positive correlation with several psychiatric disorders (e.g., anorexia nervosa and bipolar disorder) and negative correlation with several neurological phenotypes (e.g., Alzheimer's disease and ischemic stroke), even though the latter are considered to result from specific processes that occur later in life. Extensive simulations were also performed to inform how statistical power, diagnostic misclassification, and phenotypic heterogeneity influence genetic correlations. CONCLUSION The high degree of genetic correlation among many of the psychiatric disorders adds further evidence that their current clinical boundaries do not reflect distinct underlying pathogenic processes, at least on the genetic level. This suggests a deeply interconnected nature for psychiatric disorders, in contrast to neurological disorders, and underscores the need to refine psychiatric diagnostics. Genetically informed analyses may provide important "scaffolding" to support such restructuring of psychiatric nosology, which likely requires incorporating many levels of information. By contrast, we find limited evidence for widespread common genetic risk sharing among neurological disorders or across neurological and psychiatric disorders. We show that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures. Further study is needed to evaluate whether overlapping genetic contributions to psychiatric pathology may influence treatment choices. Ultimately, such developments may pave the way toward reduced heterogeneity and improved diagnosis and treatment of psychiatric disorders

From Transdisciplinary Research to Transdisciplinary Education—The Role of Schools in Contributing to Community Well-Being and Sustainable Development

This article looks at transdisciplinary research and discusses the possibilities of translating this concept into a new type of education, which we will call Transdisciplinary Education. Following the adoption of the Sustainable Development Goals by the community of states, there has been increased international recognition of education as being a key driver for sustainable development. Considering the global grand challenges of the 21st century, the integration of Education for Sustainable Development at all school levels ought to be prioritized in order to empower young people to contribute to sustainable development. Collaborating with out-of-school partners and doing research on real-world problems within their lifeworld, help students develop the competences necessary for responsible citizenship, while at the same time contributing to community well-being. Both concepts transdisciplinary research and Transdisciplinary Education acknowledge the responsibility of addressing social relevant problems and the significant role of those who are and who will be affected by these challenges. The project Science Education for Action and Engagement Towards Sustainability (SEAS) aims at analyzing different partnerships between schools and out-of-school institutions in European countries. By comparing the collaborative formats and providing a concept and method pool for educators, SEAS targets facilitating the integration of Transdisciplinary Education in formal schooling in the future. This article gives insights into the Austrian research-education collaboration k.i.d.Z.21. Drawing on experiences of k.i.d.Z.21 and taking up characteristics of transdisciplinary research, opportunities and challenges of integrating Transdisciplinary Education in formal schooling are discussed

Bridging the Action Gap by Democratizing Climate Change Education—The Case of k.i.d.Z.21 in the Context of Fridays for Future

Formal schooling frequently lacks both democratic learning culture and effective climate change education (CCE). This study analyzes the effects of the participatory CCE initiative k.i.d.Z.21 and the impacts of the current Fridays For Future (FFF) climate protests on teenagers’ climate change awareness. The mixed-methods approach comprises online pre-and post-tests, and personal interviews with selected students. k.i.d.Z.21 follows moderate constructivist, inquiry-based learning approaches and addresses 14-year old students from secondary schools in Austria and southern Germany. Considering the effectiveness of the CCE intervention of school year 2018/2019 (N = 169), quantitative findings reveal an increased mean of major components of climate change awareness, including climate-friendly behavior. When separating participants and non-participants in Fridays For Future, personal concern and refusing meat have both increased significantly only among protest participants. A closer examination of this group identifies an enhanced feeling of self-efficacy that might be triggered by perceived collective efficacy. Besides, more climate-friendly consumption behavior, as well as enhanced multiplicative action, are detected. The interviewed students also clearly assigned increased action-related components of climate change awareness to the attendance of FFF. From the findings, we conclude that democratic learning in and out of school can enhance action-related components of climate change awareness, and a combination of both can have an even stronger effect