190 research outputs found

    Uitnodiging Buckfast Belangen Verenigd Regiodag-Noord

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    Rijenbemesting: kansen, nieuwe producten en technieken : tussenrapportage 2012

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    In opdracht van het MMM voeren PRI, PPO en Altic in 2012 t/m 2014 nieuw onderzoek uit naar rijenbemesting. Nagegaan wordt in welke mate rijenbemesting de efficiëntie van de toegediende meststof verhoogd. Ook wordt nagegaan op welke bodems rijenbemesting met name voordelen biedt. In 2012 zijn veldproeven uitgevoerd in consumptieaardappel op centrale zeeklei (Lelystad) en zuidoostelijk zand (Vredepeel) en in zaaiui op zuidwestelijke zeeklei (Westmaas)

    Rondom die Apostolaat van die Kerk

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    No abstract available

    Nuclear Eg5 (kinesin spindle protein) expression predicts docetaxel response and prostate cancer aggressiveness

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    Novel biomarkers predicting prostate cancer (PCa) aggressiveness and docetaxel therapy response of PCa patients are needed. In this study the correlation between nuclear Eg5-expression, PCa docetaxel response and PCa aggressiveness was assessed. Immunohistochemical staining for nuclear Eg5 was performed on 117 archival specimens from 110 PCa patients treated with docetaxel between 2004 and 2012. Samples were histologically categorized as positive/negative. Median follow-up time from diagnosis was 11.6 years. Nuclear Eg5-expression was significantly related to docetaxel response (p=0.036) in tissues acquired within three years before docetaxel initiation. Nuclear Eg5-expression was not related to Gleason-score (p=0.994). Survival of patients after docetaxel initiation did not differ based on nuclear Eg5-expression (p=0.540). Analyzing samples taken before hormonal therapy, overall survival and time to docetaxel use were significantly decreased in patients with nuclear Eg5-expressing tumors (p<0.01). Eg5-positive nuclei were found more frequently in T4-staged tumors (p=0.04), Gleason 8-10 tumors (p=0.08), and in metastasized tumors (p<0.01). Multivariate analyses indicated that nuclear Eg5-expression may be an independent parameter for tumor aggressiveness. Limitations of a retrospective analysis apply. In conclusion, nuclear Eg5-expression may be a predictive biomarker for docetaxel response in metastatic castrate-resistant PCa patients and a prognostic biomarker for hormone-naive PCa patients. Prospective validation studies are needed

    Unsustainable fuelwood extraction from South African savannas

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    Wood and charcoal supply the majority of sub-Saharan Africa’s rural energy needs. The long-term supply of fuelwood is in jeopardy given high consumption rates. Using airborne light detection and ranging (LiDAR), we mapped and investigated savanna aboveground biomass across contrasting land uses, ranging from densely populated communal areas to highly protected areas in the Lowveld savannas of South Africa. We combined the LiDAR observations with socio-economic data, biomass production rates and fuelwood consumption rates in a supply–demand model to predict future fuelwood availability. LiDAR-based biomass maps revealed disturbance gradients around settlements up to 1.5 km, corresponding to the maximum distance walked to collect fuelwood. At current levels of fuelwood consumption (67% of households use fuelwood exclusively, with a 2% annual reduction), we calculate that biomass in the study area will be exhausted within thirteen years. We also show that it will require a 15% annual reduction in consumption for eight years to a level of 20% of households using fuelwood before the reduction in biomass appears to stabilize to sustainable levels. The severity of dwindling fuelwood reserves in African savannas underscores the importance of providing affordable energy for rural economic development.The CSIR researchers were funded by the CSIR Strategic Research Panel and the Department of Science and Technology’s Earth Observation Unit. SUCSES study (Sustainability in Communal Socio-Ecological Systems) which provided data on fuelwood use in Justicia was funded by the South African National Research Foundation. The airborne campaign and analysis was funded by the Andrew Mellon Foundation.http://iopscience.iop.org/1748-9326am201

    Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

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    A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results

    Jet size dependence of single jet suppression in lead-lead collisions at sqrt(s(NN)) = 2.76 TeV with the ATLAS detector at the LHC

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    Measurements of inclusive jet suppression in heavy ion collisions at the LHC provide direct sensitivity to the physics of jet quenching. In a sample of lead-lead collisions at sqrt(s) = 2.76 TeV corresponding to an integrated luminosity of approximately 7 inverse microbarns, ATLAS has measured jets with a calorimeter over the pseudorapidity interval |eta| < 2.1 and over the transverse momentum range 38 < pT < 210 GeV. Jets were reconstructed using the anti-kt algorithm with values for the distance parameter that determines the nominal jet radius of R = 0.2, 0.3, 0.4 and 0.5. The centrality dependence of the jet yield is characterized by the jet "central-to-peripheral ratio," Rcp. Jet production is found to be suppressed by approximately a factor of two in the 10% most central collisions relative to peripheral collisions. Rcp varies smoothly with centrality as characterized by the number of participating nucleons. The observed suppression is only weakly dependent on jet radius and transverse momentum. These results provide the first direct measurement of inclusive jet suppression in heavy ion collisions and complement previous measurements of dijet transverse energy imbalance at the LHC.Comment: 15 pages plus author list (30 pages total), 8 figures, 2 tables, submitted to Physics Letters B. All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2011-02
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