JOVENS INGRESSANDO NO MERCADO DE TRABALHO: PERCEPÇÃO E EXPECTATIVA DE JOVENS ESTUDANTES DO MUNICÍPIO DE VIDEIRA (SC)

O trabalho objetivou conhecer e analisar o novo trabalhador, seu perfil, expectativas e perspectivas do futuro em relação ao trabalho, por meio de um questionário próprio aplicado em duas escolas públicas do ensino médio e uma escola técnica do município. Nas escolas de ensino médio, a maioria dos alunos possuem de 16 a 18 anos e são do sexo feminino. Já na escola técnica a idade varia a partir de 16 anos, com maior predominância do sexo masculino. Em ambas as escolas, os alunos desejam continuar os estudos ingressando em cursos de nível superior. Sobre trabalho, os menores de 18 anos apontaram como dificuldade, a legislação vigente e a crise econômica. Uma parcela significativa não teve dificuldade para buscar o primeiro emprego e o trabalho tem correspondido às expectativas. Quanto ao futuro, nas escolas de ensino médio, os alunos pretendem ter o próprio negócio, enquanto na escola técnica, preferem continuar na carreira iniciada. Como sugestão, sugere-se a continuidade do estudo e a divulgação dos resultados para as escolas interessadas e para os empresários. Palavras-chave: Jovens. Trabalho. Perspectivas

Educação on-line em contabilidade: propensão e aspectos curriculares

Based on business education literature, findings from human resource development scholars, and considering educational and training needs in the workplace, this study focuses on analyzing executive students' (working adults students) metacognition and tendency to attend on-line MBA courses in accounting (mainly Accounting and related subjects), and whether specific content areas can be related to this phenomenon. The increasing offer of on-line courses, based on the flexibility and adaptability granted by this education mode, reinforces the relevance of understanding the factors that influence tendencies towards students' participation. According to the 2007 Brazilian Distance Education Statistical Yearbook, one out of 80 Brazilian students relied on distance education in 2006. About 2,279,000 students enrolled in various types (e.g., accredited programs, corporate education) of 889 distance courses (accredited by the Ministry of Education and State Education Councils). These figures confirm the relevance of examining this topic. The sample involved 189 graduate students enrolled in a top-ranked faceto- face Brazilian accounting MBA program, offered by a renowned Brazilian education and research institution (Institute of Accounting, Actuarial and Financial Research Foundation - FIPECAFI, an organization that supports the Department of Accounting and Actuarial Science at FEA/USP). Besides descriptive statistical analysis, studies and correlation tests, comparison of means and cluster analyses were developed to support the discussion and answer the proposed research questions. In general, findings support the assumption that the course content plays a significant role in terms of students' tendency towards on-line courses. Implications for academic and professional dimensions are also presented, along with suggestions for future studies.Com base na literatura envolvendo educação na área de negócios, bem como nos achados de pesquisadores da área de desenvolvimento de recursos humanos e considerando as necessidades educacionais e de treinamento no ambiente de trabalho, este estudo foca a análise da metacognição e propensão de estudantes-executivos (alunos adultos trabalhadores) em participar de disciplinas oferecidas on-line relacionadas a programas de MBA com ênfase em Contabilidade e áreas afins, além de explorar quais conteúdos específicos podem estar relacionados a esse fenômeno. O crescimento da oferta de cursos on-line, considerando a flexibilidade e adaptabilidade que essa modalidade de ensino permite, reforça a importância da compreensão dos fatores que influenciam a propensão à participação. Segundo dados do Anuário Brasileiro Estatístico de EAD 2007, um em cada 80 brasileiros estudoupor EAD em 2006. Foram cerca 2.279.000 alunos a distância matriculados em vários tipos (ensino credenciado, educação corporativa e em outros projetos nacionais e regionais) dentre os 889 cursos a distância (credenciados pelo Sistema de Ensino - MEC e conselhos estaduais de educação). Esses números confirmam a importância de se examinar esse tema. Foi estudada uma amostra composta de 189 alunos de pós-graduação matriculados em programas de MBA em Contabilidade, no formato presencial, oferecido por reconhecida instituição brasileira de ensino e pesquisa (a Fundação Instituto de Pesquisas Contábeis, Atuariais e Financeiras - FIPECAFI, órgão de apoio ao Departamento de Contabilidade e Atuária da FEA/USP). Além da análise estatística descritiva, estudos e testes de correlação, de comparação de médias e análise de conglomerados foram conduzidos para apoiar a discussão e resposta às questões de pesquisa aqui estabelecidas. De forma integrada, os resultados reforçam a premissa de que o conteúdo de disciplinas possui papel relevante na propensão dos estudantes em participar de cursos on-line. Implicações para as dimensões acadêmicas e profissionais, assim como sugestões para futuras pesquisas são também apresentadas

Integrative epigenomics in Sjögren´s syndrome reveals novel pathways and a strong interaction between the HLA, autoantibodies and the interferon signature

Primary Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by lymphocytic infiltration and damage of exocrine salivary and lacrimal glands. The etiology of SS is complex with environmental triggers and genetic factors involved. By conducting an integrated multi-omics study, we confirmed a vast coordinated hypomethylation and overexpression effects in IFN-related genes, what is known as the IFN signature. Stratified and conditional analyses suggest a strong interaction between SS-associated HLA genetic variation and the presence of Anti-Ro/SSA autoantibodies in driving the IFN epigenetic signature and determining SS. We report a novel epigenetic signature characterized by increased DNA methylation levels in a large number of genes enriched in pathways such as collagen metabolism and extracellular matrix organization. We identified potential new genetic variants associated with SS that might mediate their risk by altering DNA methylation or gene expression patterns, as well as disease-interacting genetic variants that exhibit regulatory function only in the SS population. Our study sheds new light on the interaction between genetics, autoantibody profiles, DNA methylation and gene expression in SS, and contributes to elucidate the genetic architecture of gene regulation in an autoimmune population

Azimuthal anisotropy of charged jet production in root s(NN)=2.76 TeV Pb-Pb collisions

We present measurements of the azimuthal dependence of charged jet production in central and semi-central root s(NN) = 2.76 TeV Pb-Pb collisions with respect to the second harmonic event plane, quantified as nu(ch)(2) (jet). Jet finding is performed employing the anti-k(T) algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero nu(ch)(2) (jet) is observed in semi-central collisions (30-50% centrality) for 20 <p(T)(ch) (jet) <90 GeV/c. The azimuthal dependence of the charged jet production is similar to the dependence observed for jets comprising both charged and neutral fragments, and compatible with measurements of the nu(2) of single charged particles at high p(T). Good agreement between the data and predictions from JEWEL, an event generator simulating parton shower evolution in the presence of a dense QCD medium, is found in semi-central collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe

Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe

La renovación de la palabra en el bicentenario de la Argentina : los colores de la mirada lingüística

El libro reúne trabajos en los que se exponen resultados de investigaciones presentadas por investigadores de Argentina, Chile, Brasil, España, Italia y Alemania en el XII Congreso de la Sociedad Argentina de Lingüística (SAL), Bicentenario: la renovación de la palabra, realizado en Mendoza, Argentina, entre el 6 y el 9 de abril de 2010. Las temáticas abordadas en los 167 capítulos muestran las grandes líneas de investigación que se desarrollan fundamentalmente en nuestro país, pero también en los otros países mencionados arriba, y señalan además las áreas que recién se inician, con poca tradición en nuestro país y que deberían fomentarse. Los trabajos aquí publicados se enmarcan dentro de las siguientes disciplinas y/o campos de investigación: Fonología, Sintaxis, Semántica y Pragmática, Lingüística Cognitiva, Análisis del Discurso, Psicolingüística, Adquisición de la Lengua, Sociolingüística y Dialectología, Didáctica de la lengua, Lingüística Aplicada, Lingüística Computacional, Historia de la Lengua y la Lingüística, Lenguas Aborígenes, Filosofía del Lenguaje, Lexicología y Terminología

O31 Integrative analysis reveals a molecular stratification of systemic autoimmune diseases

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Pseudorapidity and transverse-momentum distributions of charged particles in proton-proton collisions at root s=13 TeV

The pseudorapidity (eta) and transverse-momentum (p(T)) distributions of charged particles produced in proton-proton collisions are measured at the centre-of-mass energy root s = 13 TeV. The pseudorapidity distribution in vertical bar eta vertical bar <1.8 is reported for inelastic events and for events with at least one charged particle in vertical bar eta vertical bar <1. The pseudorapidity density of charged particles produced in the pseudorapidity region vertical bar eta vertical bar <0.5 is 5.31 +/- 0.18 and 6.46 +/- 0.19 for the two event classes, respectively. The transverse-momentum distribution of charged particles is measured in the range 0.15 <p(T) <20 GeV/c and vertical bar eta vertical bar <0.8 for events with at least one charged particle in vertical bar eta vertical bar <1. The evolution of the transverse momentum spectra of charged particles is also investigated as a function of event multiplicity. The results are compared with calculations from PYTHIA and EPOS Monte Carlo generators. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe

Centrality evolution of the charged-particle pseudorapidity density over a broad pseudorapidity range in Pb-Pb collisions at root s(NN)=2.76TeV

Peer reviewe

Loco-regional relapses from rectal cancer

Background. Loco-regional relapses (LRRs) from rectal cancer still represent a major issue in colo-rectal surgery. With the introduction of Total Mesorectal Excision (TME), LRR incidence after curative resection for rectal cancer dramatically decreased from 20–40% of cases to 2–12%. Several factors are involved in predicting LRRs, the most important of these being Dukes stage. When no treatment is performed, median survival for these patients is about 8 months. In 50% of cases LRRs are confined to the pelvis; so, the recurrent tumour can be amenable to potentially curative surgical removal, with minimal mortality and a 5 year survival rate around 20–40%. Surgery is not recommended for patients with unresectable metastases and/or infiltration of sciatic nerve, sacrum above S2–S3, and pelvic bones. We hereby report our personal experience with management of LRRs from rectal cancer. Materials and methods. We retrospectively reviewed the clinical records of 289 rectal cancer patients, treated with curative resection between 1998 and 2007. Patients were divided in two groups: A (206 patients), younger than 74 y.o.; and B (83 patients), older than 75 years old. A total of 31 patients (10.7%) developed a LRR: 24 patients of group A (11.6%) and 7 of group B (8.4%). We also included in the study 11 patients (8 in group A, 3 in group B) treated elsewhere for the primary; we thus managed in total 42 LRR patients (26 males, 16 females; mean age 64 y.). LRR was anastomotic in 37.1% of cases, central-pelvic in 31.4%, presacral in 25.7% and perineal in 5.7%. In 88.5% of patients a R0 resection had been achieved at former surgery. Mean DFS was 13.4 months. We focused on the 35 patients assessed as metastases-free at the time of the first surgery. Results. Surgical management with curative intention was possible for 23 patients (65.7%), 17 of which in group A, and consisted either of exeresis of the recurrent neoplasm (10 cases), re-resection (7 cases) or Miles operation (6 cases). In18 of these patients (15 of group A) a R0 resection was achieved. Postoperative morbidity was 42.8%; perioperative mortality was 7.1%. 3 years – OS was 28%, but it was 60% for R0 patients. Conclusion. In selected patients, especially if younger than 75, LRRs may be amenable to a multimodal approach that, in a relevant rate of cases, can lead to a potentially curative R0 resection; for the other cases a palliative management is possible, to improve overall survival and quality of life