33 research outputs found

    Caregiving for a Child with Multiple Disabilities: A Mother\u27s Story

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    Multiple disabilities does not just affect the individual, it affects caregivers as well. Once a child and parent receives the diagnosis of multiple disabilities they find themselves in a new territory, a new mindset. This study is a longitudinal autoethnographic personal narrative of a mother of a child with multiple disabilities using an intimate inquiry framework. Intimate inquiry allowed me as the researcher to explore my experiences as a reflection of the culture of caregivers of children with multiple disabilities. The purpose of this research was to attempt to understand what it means to raise a child with multiple disabilities from the inside with regards to the positive and negative transformations associated with raising and educating a child with multiple disabilities while achieving personal growth. Findings from my autoethnography suggest that caregivers from all aspects of the child’s life (family, home, school, child care, medical professionals) may share similar experiences and reactions addressed in the themes I identified. While this study specifically relates to caregiving for a child with multiple disabilities, it has the potential to relate to caregivers of any nature; those caring for their children, a spouse, or a parent or other family member

    Scapular Bracing and Alteration of Posture and Muscle Activity in Overhead Athletes With Poor Posture

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    Overhead athletes commonly have poor posture. Commercial braces are used to improve posture and function, but few researchers have examined the effects of shoulder or scapular bracing on posture and scapular muscle activity

    Intraflagellar Transport (IFT) Protein IFT25 Is a Phosphoprotein Component of IFT Complex B and Physically Interacts with IFT27 in Chlamydomonas

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    BACKGROUND: Intraflagellar transport (IFT) is the bidirectional movement of IFT particles between the cell body and the distal tip of a flagellum. Organized into complexes A and B, IFT particles are composed of at least 18 proteins. The function of IFT proteins in flagellar assembly has been extensively investigated. However, much less is known about the molecular mechanism of how IFT is regulated. METHODOLOGY/PRINCIPAL FINDINGS: We herein report the identification of a novel IFT particle protein, IFT25, in Chlamydomonas. Dephosphorylation assay revealed that IFT25 is a phosphoprotein. Biochemical analysis of temperature sensitive IFT mutants indicated that IFT25 is an IFT complex B subunit. In vitro binding assay confirmed that IFT25 binds to IFT27, a Rab-like small GTPase component of the IFT complex B. Immunofluorescence staining showed that IFT25 has a punctuate flagellar distribution as expected for an IFT protein, but displays a unique distribution pattern at the flagellar base. IFT25 co-localizes with IFT27 at the distal-most portion of basal bodies, probably the transition zones, and concentrates in the basal body region by partially overlapping with other IFT complex B subunits, such as IFT46. Sucrose density gradient centrifugation analysis demonstrated that, in flagella, the majority of IFT27 and IFT25 including both phosphorylated and non-phosphorylated forms are cosedimented with other complex B subunits in the 16S fractions. In contrast, in cell body, only a fraction of IFT25 and IFT27 is integrated into the preassembled complex B, and IFT25 detected in complex B is preferentially phosphorylated. CONCLUSION/SIGNIFICANCE: IFT25 is a phosphoprotein component of IFT particle complex B. IFT25 directly interacts with IFT27, and these two proteins likely form a subcomplex in vivo. We postulate that the association and disassociation between the subcomplex of IFT25 and IFT27 and complex B might be involved in the regulation of IFT

    Search for dark matter at √s=13 TeV in final states containing an energetic photon and large missing transverse momentum with the ATLAS detector

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    Results of a search for physics beyond the Standard Model in events containing an energetic photon and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. As the number of events observed in data, corresponding to an integrated luminosity of 36.1 fb−1 of proton–proton collisions at a centre-of-mass energy of 13 TeV, is in agreement with the Standard Model expectations, model-independent limits are set on the fiducial cross section for the production of events in this final state. Exclusion limits are also placed in models where dark-matter candidates are pair-produced. For dark-matter production via an axial-vector or a vector mediator in the s-channel, this search excludes mediator masses below 750–1200 GeV for dark-matter candidate masses below 230–480 GeV at 95% confidence level, depending on the couplings. In an effective theory of dark-matter production, the limits restrict the value of the suppression scale M∗ to be above 790 GeV at 95% confidence level. A limit is also reported on the production of a high-mass scalar resonance by processes beyond the Standard Model, in which the resonance decays to Zγ and the Z boson subsequently decays into neutrinos

    Caregiving for a Child with Multiple Disabilities: A Mother\u27s Story

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    Multiple disabilities does not just affect the individual, it affects caregivers as well. Once a child and parent receives the diagnosis of multiple disabilities they find themselves in a new territory, a new mindset. This study is a longitudinal autoethnographic personal narrative of a mother of a child with multiple disabilities using an intimate inquiry framework. Intimate inquiry allowed me as the researcher to explore my experiences as a reflection of the culture of caregivers of children with multiple disabilities. The purpose of this research was to attempt to understand what it means to raise a child with multiple disabilities from the inside with regards to the positive and negative transformations associated with raising and educating a child with multiple disabilities while achieving personal growth. Findings from my autoethnography suggest that caregivers from all aspects of the child’s life (family, home, school, child care, medical professionals) may share similar experiences and reactions addressed in the themes I identified. While this study specifically relates to caregiving for a child with multiple disabilities, it has the potential to relate to caregivers of any nature; those caring for their children, a spouse, or a parent or other family member

    Seeing is for Self-Control: Motivated Perceptual Processes Aid Temptation Resistance

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    As people work toward achieving goals, they often encounter temptations that threaten to throw them off course. How do people resolve the conflicts that arise when their immediate desires are at odds with their long-term goals? A great deal of research focuses on cognitive processes that aid self-control, exploring mechanisms and strategies related to how people think about, judge, and evaluate temptations. My dissertation instead tests perceptual routes to self-control. I explore biases that occur as people perceive and interpret visual information during conflicts. I ask whether people who are able to successfully resolve self-control conflicts not only think about the world in goal-promoting ways, but perceive it in goal-promoting ways as well. In two lines of research, I explored two perceptual biases–perceptual downgrading and distancing–that arise during self-control conflicts to help people manage threats to their long-term goals. In the first set of studies, I explored motivated perceptual processes within romantic self-control conflicts. I tested whether people perceptually downgrade attractive others who represent a potential threat to their relationship goals. Compared to single individuals, people in relationships perceived attractive, available others as less physically attractive. This occurred to the greatest extent among people who were strongly committed to and satisfied with their current relationships. The results from this line of work suggest people who are highly motivated to protect their long-term romantic relationship goals from temptations exhibit a perceptual self-control strategy that helps to weaken the temptation. In the second set of studies, I explored motivated perceptual processes within dieting self-control conflicts. In three studies, I tested whether people with strong dieting goals perceived threatening unhealthy foods as perceptually distant. Compared to unrestrained eaters, people with goals to restrict their unhealthy food intake saw snack foods as further away. This was especially likely to occur among people who were successful at managing their dieting goals. Moreover, perceived distance affected people's evaluations of and their subsequent motivations to pursue a temptation. Snacks that were further away were rated as less appealing and, as a result, participants were less likely to want to eat them. The results from this second line of work suggest successful resolution of dieting self-control conflicts may be aided by perceptual distancing, a self-control process that decreases people's motivation to give in to tempting snack foods. Across the studies, I find evidence for perceptual biases that arise during self-control conflicts and suggest functional links between these perceptual biases and behavioral efforts to resist temptations. In the final chapter, I discuss the theoretical and applied import of incorporating motivated perceptual processes into models of self-control, argue for the unique role perceptual biases play in the self-regulatory process, pose open questions and put forth testable hypotheses for future research to explore, and lay the foundation for a broader theory of motivated perceptual processes across multiple stages of goal pursuit

    Goals as identities and easier goal pursuit

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    "Goals as identities: Boosting health goal-centrality for easier goal pursuit

    Political Opposites Do Not Attract: The Effects of Ideological Dissimilarity on Impression Formation

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    Past research shows that people like others who are similar to themselves, and that political partisans tend to dislike those with opposing viewpoints. Two studies examined how initial person impressions changed after discovering that the target held similar or dissimilar political beliefs. Using potential mates as targets, we found that participants liked targets less, were less romantically interested in targets, and rated targets as less attractive after discovering political dissimilarity with them. Further, they became more uncomfortable with targets after discovering ideological dissimilarity. Theoretical implications and suggestions for future research are discussed

    Perceptual Differences & Transgender Individuals

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