5,909 research outputs found
Two Separate Effects Contribute to Regulatory T Cell Defect in Systemic Lupus Erythematosus Patients and Their Unaffected Relatives
- Author
- Publication venue
- 'Wiley'
- Publication date
- 16/06/2017
- Field of study
Forkhead box P3 (FoxP3)+ regulatory T cells (Tregs ) are functionally deficient in systemic lupus erythematosus (SLE), characterized by reduced surface CD25 [the interleukin (IL)-2 receptor alpha chain]. Low-dose IL-2 therapy is a promising current approach to correct this defect. To elucidate the origins of the SLE Treg phenotype, we studied its role through developmentally defined regulatory T cell (Treg ) subsets in 45 SLE patients, 103 SLE-unaffected first-degree relatives and 61 unrelated healthy control subjects, and genetic association with the CD25-encoding IL2RA locus. We identified two separate, uncorrelated effects contributing to Treg CD25. (1) SLE patients and unaffected relatives remarkably shared CD25 reduction versus controls, particularly in the developmentally earliest CD4+ FoxP3+ CD45RO- CD31+ recent thymic emigrant Tregs . This first component effect influenced the proportions of circulating CD4+ FoxP3high CD45RO+ activated Tregs . (2) In contrast, patients and unaffected relatives differed sharply in their activated Treg CD25 state: while relatives as control subjects up-regulated CD25 strongly in these cells during differentiation from naive Tregs , SLE patients specifically failed to do so. This CD25 up-regulation depended upon IL2RA genetic variation and was related functionally to the proliferation of activated Tregs , but not to their circulating numbers. Both effects were found related to T cell IL-2 production. Our results point to (1) a heritable, intrathymic mechanism responsible for reduced CD25 on early Tregs and decreased activation capacity in an extended risk population, which can be compensated by (2) functionally independent CD25 up-regulation upon peripheral Treg activation that is selectively deficient in patients. We expect that Treg -directed therapies can be monitored more effectively when taking this distinction into account.info:eu-repo/semantics/publishedVersio
Uptake of oxLDL and IL-10 production by macrophages requires PAFR and CD36 recruitment into the same lipid rafts
- Author
- Andrea Cignarella
- B Halvorsen
- C Poisson
- CH Serezani
- CR Stewart
- D Gao
- Daniel F. J. Ketelhuth
- DE Greenwalt
- DF Ketelhuth
- DF Ketelhuth
- FJ Rios
- FJ Rios
- FJ Rios
- Francisco J. O. Rios
- H Itabe
- H Sakai
- I Brochériou
- JB Massey
- JP Gaut
- JQ Davies
- K Hoebe
- KA Powers
- KJ Livak
- KJ Moore
- L Frémont
- M Fallahi-Sichani
- M Febbraio
- M Febbraio
- M Triantafilou
- M Triantafilou
- M Yuasa-Kawase
- MA Bouhlel
- Marianna M. Koga
- Mateus Pecenin
- Matheus Ferracini
- MD Carvalho
- N Li
- S Chatterjee
- S Kazerounian
- S Kazerounian
- S Lemaire-Ewing
- S Nozaki
- S Pégorier
- S. Jancar
- SH Shin
- SI de Oliveira
- SN Verouti
- T Kiyanagi
- T Rubic
- Yajuan Wang
- YI Miller
- YS Bae
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2013
- Field of study
Macrophage interaction with oxidized low-density lipoprotein (oxLDL) leads to its differentiation into foam cells and cytokine production, contributing to atherosclerosis development. In a previous study, we showed that CD36 and the receptor for platelet-activating factor (PAFR) are required for oxLDL to activate gene transcription for cytokines and CD36. Here, we investigated the localization and physical interaction of CD36 and PAFR in macrophages stimulated with oxLDL. We found that blocking CD36 or PAFR decreases oxLDL uptake and IL-10 production. OxLDL induces IL-10 mRNA expression only in HEK293T expressing both receptors (PAFR and CD36). OxLDL does not induce IL-12 production. The lipid rafts disruption by treatment with βCD reduces the oxLDL uptake and IL-10 production. OxLDL induces co-immunoprecipitation of PAFR and CD36 with the constitutive raft protein flotillin-1, and colocalization with the lipid raft-marker GM1-ganglioside. Finally, we found colocalization of PAFR and CD36 in macrophages from human atherosclerotic plaques. Our results show that oxLDL induces the recruitment of PAFR and CD36 into the same lipid rafts, which is important for oxLDL uptake and IL-10 production. This study provided new insights into how oxLDL interact with macrophages and contributing to atherosclerosis development
Emergence of quasi-metallic state in disordered 2D electron gas due to strong interactions
- Author
- A. Gold
- A. Gold
- A.A. Pastor
- A.A. Shashkin
- A.J. McKane
- A.L. Efros
- A.M. Finkelstein
- A.M. Finkelstein
- A.M.M. Pruisken
- A.M.M. Pruisken
- A.M.M. Pruisken
- A.R. Hamilton
- B. Rosenstein
- B. Tanatar
- B.L. Altshuler
- B.L. Altshuler
- C. Castellani
- C.M. Varma
- C.S. Ting
- D. Belitz
- D. Li
- D. Li
- D. Vollhardt
- D. Vollhardt
- E. Abrahams
- E. Abrahams
- E. Abrahams
- F. Wegner
- F. Wegner
- G. Zala
- G. Zala
- G.F. Giuliani
- M. Bando
- M.A. Baranov
- M.A. Baranov
- M.V. Sadovskii
- M.Y. Simmons
- P. Schwab
- P.A. Lee
- P.T. Coleridge
- Q. Si
- R. Asgari
- R.J.F. Leote de Carvalho
- S. Chakravarty
- S. Hikami
- S. Yarlagadda
- S.A. Vitkalov
- S.S. Safonov
- S.V. Kravchenko
- S.V. Kravchenko
- T.K. Lee
- T.R. Kirkpatrick
- Tran Minh-Tien
- V.M. Pudalov
- V.M. Pudalov
- V.Y. But’ko
- W.L. McMillan
- Y. Imry
- Y. Kwon
- Y.-R. Jang
- Z. Wilamowski
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 28/10/2003
- Field of study
The interrelation between disorder and interactions in two dimensional
electron liquid is studied beyond weak coupling perturbation theory. Strong
repulsion significantly reduces the electronic density of states on the Fermi
level. This makes the electron liquid more rigid and strongly suppresses
elastic scattering off impurities. As a result the weak localization, although
ultimately present at zero temperature and infinite sample size, is
unobservable at experimentally accessible temperature at high enough densities.
Therefore practically there exists a well defined metallic state. We study
diffusion of electrons in this state and find that the diffusion pole is
significantly modified due to "mixture" with static photons similar to the
Anderson - Higgs mechanism in superconductivity. As a result several effects
stemming from the long range nature of diffusion like the Aronov - Altshuler
logarithmic corrections to conductivity are less pronounced.Comment: to appear in Phys. Rev.
The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection—evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology
- Author
- A Ames 3rd
- A Carvalho
- A Gaspar
- A Maulik
- AA Neuhaus
- AC Schinzel
- AD Sloth
- Arjun K. Ghosh
- AS Hazell
- B Ibanez
- B Ibanez
- Borja Ibanez
- CC Smith
- CE Murry
- CP Baines
- D Li
- Daniel I. Bromage
- Derek M. Yellon
- DI Bromage
- DJ Hausenloy
- DJ Hausenloy
- DJ Hausenloy
- DJ Hausenloy
- DJ Hausenloy
- ET Chouchani
- F Chauveau
- F Chen
- F Pedersen
- G Heusch
- G Heusch
- G Heusch
- G Heusch
- G Heusch
- G Heusch
- G Heusch
- G Heusch
- G Heusch
- G Heusch
- G Heusch
- GA Donnan
- GA Donnan
- Gerd Heusch
- GF Baxter
- GP Fadini
- GW Stone
- H Sandhu
- HA Cabrera-Fuentes
- Hans Erik Bøtker
- HE Botker
- Helen Maddock
- I Eitel
- J Aronowski
- J Astrup
- J Bai
- J Inserte
- J Johnsen
- JC Wang
- JE Jung
- JL Saver
- JM Vicencio
- John Cunningham
- JP Audia
- JPG Sluijter
- JS Balami
- JV McGowan
- K Szummer
- KL Furie
- L Zhang
- M Fisher
- M Gharanei
- M Gharanei
- M Schmidt
- M Thielmann
- Malcolm Walker
- Marlene Wiart
- Maryna V. Basalay
- MD Ginsberg
- Michel Ovize
- MV Cohen
- N Nighoghossian
- P Kleinbongard
- P Meybohm
- PA Lapchak
- PA Lapchak
- Petra Kleinbongard
- R Bell
- R Bonita
- R Chung
- R Madonna
- RA Kloner
- Richard D. Carr
- RM Bell
- RM Bell
- Robert M. Bell
- RR Liu
- RR Moustafa
- S Lecour
- S Pundik
- SA Crone
- Sandrine Lecour
- Sapna Arjun
- Sean M. Davidson
- SI Savitz
- SM Davidson
- SM Davidson
- SM Davidson
- SM Davidson
- SP Jones
- TA Zelniker
- VE O’Collins
- VE O’Collins
- VL Feigin
- W Li
- X Rossello
- X Rossello
- X Xu
- Y Li
- Z Vermeulen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Due to its poor capacity for regeneration, the heart is particularly sensitive to the loss of contractile cardiomyocytes. The onslaught of damage caused by ischaemia and reperfusion, occurring during an acute myocardial infarction and the subsequent reperfusion therapy, can wipe out upwards of a billion cardiomyocytes. A similar program of cell death can cause the irreversible loss of neurons in ischaemic stroke. Similar pathways of lethal cell injury can contribute to other pathologies such as left ventricular dysfunction and heart failure caused by cancer therapy. Consequently, strategies designed to protect the heart from lethal cell injury have the potential to be applicable across all three pathologies. The investigators meeting at the 10th Hatter Cardiovascular Institute workshop examined the parallels between ST-segment elevation myocardial infarction (STEMI), ischaemic stroke, and other pathologies that cause the loss of cardiomyocytes including cancer therapeutic cardiotoxicity. They examined the prospects for protection by remote ischaemic conditioning (RIC) in each scenario, and evaluated impasses and novel opportunities for cellular protection, with the future landscape for RIC in the clinical setting to be determined by the outcome of the large ERIC-PPCI/CONDI2 study. It was agreed that the way forward must include measures to improve experimental methodologies, such that they better reflect the clinical scenario and to judiciously select combinations of therapies targeting specific pathways of cellular death and injury
The development of a 16S rRNA gene based PCR for the identification of Streptococcus pneumoniae and comparison with four other species specific PCR assays
- Author
- A Ortqvist
- Bart Saerens
- CA Dias
- D Llull
- D Rozkiewicz
- Elife Alkan
- ER Keith
- G Carvalho Mda
- GM Abdeldaim
- JC Arbique
- JC McAvin
- KE Morrison
- L Spanjaard
- M Vaneechoutte
- Mario Vaneechoutte
- N Suzuki
- N Suzuki
- Nabil Abdullah El Aila
- Pieter Deschaght
- R Verhelst
- Rita Verhelst
- RW Bentley
- S Nunes
- S Rintamaki
- SI Aguiar
- Stefan Emler
- T Kaijalainen
- T Kaijalainen
- Tarja Kaijalainen
- Thierry De Baere
- TO Messmer
- Publication venue
- BioMed Central
- Publication date
- 01/01/2010
- Field of study
<p>Abstract</p> <p>Background</p> <p><it>Streptococcus pneumoniae </it>is one of the most frequently encountered pathogens in humans but its differentiation from closely related but less pathogenic streptococci remains a challenge.</p> <p>Methods</p> <p>This report describes a newly-developed PCR assay (Spne-PCR), amplifying a 217 bp product of the 16S rRNA gene of <it>S. pneumoniae</it>, and its performance compared to other genotypic and phenotypic tests.</p> <p>Results</p> <p>The new PCR assay designed in this study, proved to be specific at 57°C for <it>S. pneumoniae</it>, not amplifying <it>S. pseudopneumoniae </it>or any other streptococcal strain or any strains from other upper airway pathogenic species. PCR assays (psaA, LytA, ply, spn9802-PCR) were previously described for the specific amplification of <it>S. pneumoniae</it>, but <it>psaA</it>-PCR was the only one found not to cross-react with <it>S. pseudopneumoniae</it>.</p> <p>Conclusion</p> <p>Spne-PCR, developed for this study, and psaA-PCR were the only two assays which did not mis-identify <it>S. pseudopneumoniae </it>as <it>S. pneumoniae</it>. Four other PCR assays and the AccuProbe assay were unable to distinguish between these species.</p
Connectivity and vagility determine beta diversity and nestedness in North American and European freshwater fish
- Author
- Almeida-Neto
- Almeida-Neto
- Almeida-Neto
- Aranda
- Astorga
- Atmar
- Banarescu
- Baselga
- Baselga
- Baselga
- Baselga
- Baselga
- Baselga
- Baselga
- Batzer
- Bianco
- Bjorholm
- Blanchet
- Carvalho
- Chapman
- Crossman
- Dapporto
- Dias
- Dobrovolski
- Dullinger
- Freijeiro
- Goslee
- Griffiths
- Griffiths
- Griffiths
- Griffiths
- Grönroos
- Heino
- Heino
- Henriques-Silva
- Illies
- Jacquemin
- Keil
- Kottelat
- Leprieur
- Leprieur
- Lucas
- Maitland
- Matthews
- McAbendroth
- McDowall
- Miller
- Normand
- Northcote
- Page
- Presley
- Qian
- Qian
- R Development Core Team
- Reyjol
- Rosenfield
- Si
- Smith
- Smith
- Soininen
- Steinitz
- Svenning
- Tisseuil
- Ulrich
- Ulrich
- Ulrich
- Wen
- Whittaker
- Publication venue
- 'Wiley'
- Publication date
- 01/08/2017
- Field of study
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alda Junior WL
- Alexander J
- Aliev T
- Almeida N
- Alver B
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
- Antonelli L
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Apresyan A
- Aranyi A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Arora S
- Asawatangtrakuldee C
- Asghar MI
- Askew A
- Assran Y
- Ata M
- Atac M
- Atramentov O
- Attikis A
- Auffray E
- Autermann C
- Auzinger G
- Avdeeva E
- Avery P
- Avetisyan A
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzolini V
- Azzurri P
- Baarmand MM
- Babb J
- Bacchetta N
- Bachtis M
- Baden A
- Baeni L
- Baesso P
- Baffioni S
- Bagliesi G
- Bai Y
- Baillon P
- Bainbridge R
- Bakhshiansohi H
- Bakirci MN
- Bakken JA
- Balazs M
- Ball AH
- Ball G
- Ban Y
- Banerjee S
- Banerjee S
- Bansal S
- Banzuzi K
- Barbagli G
- Barberis E
- Barbone L
- Bardak C
- Barfuss AF
- Bargassa P
- Barge D
- Baringer P
- Barker A
- Barnes VE
- Barnett BA
- Barney D
- Barone L
- Barrett M
- Bartalini P
- Barth C
- Basegmez S
- Basso L
- Battilana C
- Baty C
- Bauer G
- Bauerdick LAT
- Baumgartel D
- Baur U
- Bayshev I
- Bazterra VE
- Bean A
- Beauceron S
- Beaudette F
- Beaupere N
- Bedjidian M
- Beernaert K
- Behrenhoff W
- Behrens U
- Belforte S
- Beliy N
- Belknap D
- Bell AJ
- Bell KW
- Bellan P
- Bellan R
- Bellato M
- Bellinger JN
- Belotelov I
- Belyaev A
- Belyaev A
- Benaglia A
- Bencze G
- Bendavid J
- Benedetti D
- Benelli G
- Benhabib L
- Beni N
- Benucci L
- Benussi L
- Benvenuti AC
- Beranek S
- Beretvas A
- Bergauer T
- Berger J
- Bergholz M
- Beri SB
- Bernardes CA
- Bernardini J
- Bernet C
- Berry D
- Berry E
- Berryhill J
- Bertl W
- Berzano U
- Besancon M
- Betchart B
- Bethani A
- Betts RR
- Beuselinck R
- Bhat PC
- Bhatnagar V
- Bhattacharya S
- Bhattacharya S
- Bhatti A
- Bialas W
- Bialkowska H
- Bian JG
- Bianchi G
- Bianchini L
- Bianco S
- Biasini M
- Biino C
- Bilei GM
- Bilin B
- Bilinskas MJ
- Bilki B
- Bilmis S
- Biselli A
- Bisello D
- Bitioukov S
- Blekman F
- Blobel V
- Bloch D
- Bloch I
- Bloch P
- Bloom K
- Bluj M
- Blumenfeld B
- Blyweert S
- Bobrovskyi S
- Boccali T
- Bocci A
- Bochenek J
- Bodek A
- Bodin D
- Boimska B
- Boldizsar L
- Bolla G
- Bolognesi S
- Bolton T
- Bonacorsi D
- Bonato A
- Bondu O
- Bontenackels M
- Boos E
- Bornheim A
- Borras K
- Borrello L
- Bortignon P
- Bortoletto D
- Bose S
- Bose T
- Bostock F
- Botta C
- Boudoul G
- Boulahouache C
- Boumediene D
- Bourilkov D
- Boutemeur M
- Boutle S
- Braibant-Giacomelli S
- Branca A
- Branson JG
- Breedon R
- Breto G
- Breuker H
- Brew C
- Brigliadori L
- Brigljevic V
- Brinkerhoff A
- Broccolo G
- Brochero Cifuentes JA
- Brom JM
- Brona G
- Brooke JJ
- Broutin C
- Brown RM
- Brownson E
- Brun H
- Bruno G
- Bryer AG
- Buchmann MA
- Buchmuller O
- Bunkowski K
- Bunn J
- Buontempo S
- Burgmeier A
- Burkett K
- Busson P
- Busza W
- Butler JN
- Butler PH
- Butt J
- Butz E
- Bylsma B
- Cabrera A
- Cabrillo IJ
- Caebergs T
- Cakir A
- Calabria C
- Calderon De La Barca Sanchez M
- Calderon A
- Cali IA
- Calligaris L
- Callner J
- Calvert B
- Calvo E
- Campagnari C
- Campbell A
- Camporesi T
- Capiluppi P
- Caponeri B
- Cappello G
- Cardaci M
- Carlin R
- Carlsmith D
- Carrillo Moreno S
- Carroll R
- Cartiglia N
- Carvalho W
- Casal B
- Casimiro Linares E
- Castaldi R
- Castello R
- Castilla-Valdez H
- Castro A
- Castro E
- Caudron J
- Caulfield M
- Cavallari F
- Cavallo FR
- Cavallo N
- Cavanaugh R
- Ceard L
- Ceballos GG
- Cepeda M
- Cerati GB
- Cerci DS
- Cerci S
- Cerizza G
- Cerminara G
- Cerrada M
- Chabert EC
- Chadwick M
- Chakaberia I
- Chamizo Llatas M
- Chan M
- Chang P
- Chang S
- Chang YH
- Chang YH
- Chang YW
- Chanon N
- Chao Y
- Charaf O
- Charlot C
- Chasco M
- Chasserat J
- Chatrchyan S
- Chatterjee A
- Chauhan S
- Checchia P
- Chen GM
- Chen HS
- Chen J
- Chen KF
- Chen KH
- Chen M
- Chen Y
- Chen Z
- Cherepanov V
- Chertok M
- Chetluru V
- Cheung HWK
- Chhibra SS
- Chierici R
- Chiochia V
- Chiorboli M
- Chlebana F
- Cho Y
- Choi M
- Choi S
- Choi Y
- Choi YK
- Chou JP
- Choudhary BC
- Choudhury RK
- Choudhury S
- Christiansen T
- Chuang SH
- Chung J
- Chung YS
- Chwalek T
- Ciesielski R
- Cihangir S
- Cimmino A
- Cipriano PMR
- Cirino G
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
- Clare R
- Clarida W
- Clement E
- Clerbaux B
- Cline D
- CMS Collaboration
- Cockerill DJA
- Codispoti G
- Colafranceschi S
- Colaleo A
- Cole JE
- Colino N
- Collard C
- Colling D
- Conetti S
- Contardo D
- Conte E
- Contreras-Campana C
- Contreras-Campana E
- Conway J
- Conway R
- Cooper SI
- Cooper W
- Cornelis T
- Correa Martins Junior M
- Cortezon EP
- Cossutti F
- Costa M
- Costa S
- Costantini S
- Coughlan JA
- Cousins R
- Covarelli R
- Cox B
- Cox PT
- Creanza D
- Cremaldi LM
- Cripps N
- Cuevas J
- Cuffiani M
- Cumalat JP
- Cuplov V
- Cure B
- Cushman P
- Cussans D
- Custodio A
- Cutajar M
- Cutts D
- Cwiok M
- Czellar S
- D'Agnolo RT
- D'Alessandro R
- D'Alfonso M
- D'Enterria D
- D'Hondt J
- Da Costa EM
- Daci N
- Dahmes B
- Dahms T
- Dallavalle GM
- Damgov J
- Damiao DD
- Dammann D
- Danielson T
- Das S
- Daskalakis G
- Dasu S
- Daubie E
- Dauncey P
- David A
- Davids M
- Davies G
- de Barbaro P
- De Benedetti A
- De Boer W
- de Cassagnac RG
- De Cosa A
- de Fatis TT
- De Filippis N
- De Gruttola M
- De Guio F
- De Jeneret JD
- De La Cruz B
- De La Cruz-Burelo E
- De Lentdecker G
- De Mattia M
- de Monchenault GH
- De Oliveira Martins C
- De Palma M
- De Roeck A
- de Troconiz JF
- De Visscher S
- De Wolf EA
- Deisher A
- Deiters K
- Dejardin M
- del Arbol PMR
- Del Re D
- Delaere C
- Delgado Peris A
- Deliomeroglu M
- Dell'Orso R
- Della Negra M
- Della Ricca G
- Demaria N
- Demina R
- Demortier L
- Denegri D
- Deniz M
- Depasse P
- Dermenev A
- Dero V
- Dhingra N
- Di Giovanni GP
- Di Guida S
- Di Marco E
- Di Matteo L
- Diamond B
- Dias FA
- Diemoz M
- Dierlamm A
- Dietz C
- Dietz-Laursonn E
- Diez Pardos C
- Dimitrov A
- Dinardo ME
- Dirkes G
- Dissertori G
- Dittmar M
- Djordjevic M
- Dobrzynski L
- Dobson M
- Dobur D
- Doesburg R
- Dogangun O
- Dolen J
- Dominguez Vazquez D
- Dominguez A
- Dominik W
- Don CKK
- Dorigo T
- Dorney B
- Doroba K
- Dozen C
- Draeger J
- Dragicevic M
- Dragoiu C
- Drell BR
- Dremin I
- Drouhin F
- Drozdetskiy A
- du Pree T
- Duarte Campderros J
- Duarte J
- Dubinin M
- Dudero PR
- Dudko L
- Duenser M
- Dugad S
- Duggan D
- Dumanoglu I
- Dupont-Sagorin N
- Duric S
- Duris J
- Durkin LS
- Duru F
- Dutta D
- Dutta S
- Dutta V
- Dzelalija M
- Eads M
- Eartly DP
- Eckerlin G
- Ecklund KM
- Eckstein D
- Edelhoff M
- Edelmaier CJ
- Eerola P
- Efron J
- Eggert N
- Ekmedzic M
- El Mamouni H
- Elgammal S
- Elliott-Peisert A
- Ellison J
- Elmer P
- Elvira VD
- Enderle H
- Engh D
- Eno SC
- Epshteyn V
- Erbacher R
- Erdmann M
- Erdmann W
- Erfle J
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- Sfiligoi I
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- Yilmaz Y
- Yohay R
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- Yumiceva F
- Yun JC
- Zabel J
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- Zakaria M
- Zalewski P
- Zanetti M
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- Zeinali M
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- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
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- Abolins M
- Abramowicz H
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- Acharya BS
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- Zhemchugov A
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- Zieminska D
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- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
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- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
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- Wissing C
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- Womersley WJ
- Won S
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- Wood J
- Wood JS
- Worm SD
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- Wulz C-E
- Wyslouch B
- Xiao H
- Xie S
- Xu M
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- Yalvac M
- Yang F
- Yang M
- Yang Y
- Yang ZC
- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV
- Author
- Abbaneo D.
- Abbiendi G.
- Abbrescia M.
- Abdullin S.
- Abercrombie D.
- Acharya H.
- Acosta D.
- Acosta J. G.
- Adam W.
- Adams M. R.
- Adams T.
- Adzic P.
- Afanasiev S.
- Agapitos A.
- Agarwal G.
- Aggleton R.
- Agram J.-L.
- Aguilar-Benitez M.
- Ahmad A.
- Ahmad M.
- Ahmad M.
- Ahuja S.
- Akbiyik M.
- Akchurin N.
- Akgun B.
- Albajar C.
- Albergo S.
- Albert A.
- Albrow M.
- Alcaraz Maestre J.
- Aldaya Martin M.
- Aleksandrov A.
- Alexander J.
- Alhusseini M.
- Alimena J.
- Alison J.
- Allen B.
- Almond J.
- Alvarez Gonzalez B.
- Alverson G.
- Alves G. A.
- Aly R.
- Alyari M.
- Amapane N.
- Ambrogi F.
- Amendola C.
- Amin N.
- Amsler C.
- Anagnostou G.
- Anderson D.
- Andrea J.
- Andreev V.
- Andreev Yu.
- Andrews M. B.
- Androsov K.
- Ang L.
- Antchev G.
- Antunovic Z.
- Apanasevich L.
- Apollinari G.
- Apresyan A.
- Apyan A.
- Araujo M.
- Arcaro D.
- Arcidiacono R.
- Arenton M. W.
- Argiro S.
- Arneodo M.
- Asavapibhop B.
- Asawatangtrakuldee C.
- Asenov P.
- Askew A.
- Asmuss P.
- Assran Y.
- Atakisi I. O.
- Ather M. W.
- Attikis A.
- Auffray E.
- Aushev T.
- Autermann C.
- Auzinger G.
- Avati V.
- Avery P.
- Avila C.
- Awan M. I. M.
- Ayala E.
- Azarkin M.
- Azhgirey I.
- Aziz T.
- Azzi P.
- Azzurri P.
- Baarmand M. M.
- Babaev A.
- Babounikau I.
- Bacchetta N.
- Bachiller I.
- Bachtis M.
- Backhaus M.
- Baden A.
- Baechler J.
- Bagliesi G.
- Bahinipati S.
- Baillon P.
- Bainbridge R.
- Bakas G.
- Bakhshiansohi H.
- Baldenegro Barrera C.
- Ball A. H.
- Ban Y.
- Band R.
- Banerjee S.
- Banerjee S.
- Bansal S.
- Barbagli G.
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- Özçelik Ö.
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 24/04/2020
- Field of study
The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8 TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum
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