The ultraviolet visibility and quantitative morphology of galactic disks at low and high redshift

We used ultraviolet (200 nm) images of the local spiral galaxies M33, M51, M81, M100, M101 to compute morphological parameters of galactic disks at this wavelength : half-light radius $r_{hl}$, surface brightness distributions, asymmetries ($A$) and concentrations ($C_A$). The visibility and the evolution of the morphological parameters are studied as a function of the redshift. The main results are : local spiral galaxies would be hardly observed and classified if projected at high redshifts (z $\ge$ 1) unless a strong luminosity evolution is assumed. Consequently, the non-detection of large galactic disks cannot be used without caution as a constraint on the evolution of galatic disks. Spiral galaxies observed in ultraviolet appear more irregular since the contribution from the young stellar population becomes predominent. When these galaxies are put in a (log $A$ vs. log $C_A$) diagram, they move to the irregul ar sector defined at visible wavelengths. Moreover, the log $A$ parameter is degenerate and cannot be used for an efficient classification of morphological ultraviolet types. The analysis of high redshift galaxies cannot be carried out in a reliable way so far and a multi-wavelength approach is required if one does not want to misinterpret the data.Comment: 12 pages, accepted for publication in A&A on 15 January 200

Curvature in the color-magnitude relation but not in color-sigma: Major dry mergers at M* > 2 x 10^11 Msun?

The color-magnitude relation of early-type galaxies differs slightly but significantly from a pure power-law, curving downwards at low and upwards at large luminosities (Mr>-20.5 and Mr<-22.5). This remains true of the color-size relation, and is even more apparent with stellar mass (M* < 3x10^10 Msun and M* > 2x10^11 Msun). The upwards curvature at the massive end does not appear to be due to stellar population effects. In contrast, the color-sigma relation is well-described by a single power law. Since major dry mergers change neither the colors nor sigma, but they do change masses and sizes, the clear features observed in the scaling relations with M*, but not with sigma > 150 km/s, suggest that M* > 2x10^11 Msun is the scale above which major dry mergers dominate the assembly history. We discuss three models of the merger histories since z ~ 1 which are compatible with our measurements. In all three models, dry mergers are responsible for the flattening of the color-M* relation at M* > 3x10^10 Msun - wet mergers only matter at smaller masses. At M* > 2 x 10^11 Msun, the merger histories in one model are dominated by major rather than minor dry mergers, as suggested by the axis ratio and color gradient trends. In another, although both major and minor mergers occur at the high mass end, the minor mergers contribute primarily to the formation of the ICL, rather than to the mass growth of the central massive galaxy. A final model assumes that the reddest objects were assembled by a mix of major and minor dry mergers.Comment: 22 pages, 22 figures and 3 tables. Accepted for publication in MNRA

Galaxy Clustering Evolution in the UH8K Weak Lensing Fields

We present measurements of the two-point galaxy angular correlation function as a function of apparent magnitude, color, and morphology. We present new galaxy number counts to limiting magnitudes of I=24.0 and V=25.0. We find $\omega(\theta)$ to be well described by a power-law of slope -0.8. We find the amplitude of the correlation function to decrease monotonically with increasingly faint apparent magnitude. We compare with predictions utilizing redshift distributions based on deep spectroscopic observations. We conclude that simple redshift-dependent models which characterize evolution by means of the epsilon parameter inadequately describe the observations. We find a strong clustering dependence on V-I color because galaxies of extreme color lie at similar redshifts and the angular correlation functions for these samples are minimally diluted by chance projections. We then present the first attempt to investigate the redshift evolution of clustering, utilizing a population of galaxies of the same morphological type and absolute luminosity. We study the dependence of $\omega(\theta)$ on redshift for Lstar early-type galaxies in the redshift range 0.2<z<0.9. Although uncertainties are large, we find the evolution in the clustering of these galaxies to be consistent with stable clustering [epsilon=0]. We find Lstar early-type galaxies to cluster slightly more strongly (rnought = 5.25\pm0.28 \hMpc assuming epsilon=0) than the local full field population. This is in good agreement with the 2dFGRS value for Lstar early-type galaxies in the local universe (abridged).Comment: 41 pages, including 12 figs, 10 tables, to appear in Ap

The Canada-France deep fields survey-II: Lyman-break galaxies and galaxy clustering at z~3

(abridged) We present a large sample of z~3 U- band dropout galaxies extracted from the Canada-France deep fields survey (CFDF). Our catalogue covers an effective area of ~1700 arcmin^2 divided between three large, contiguous fields separated widely on the sky. To IAB=24.5, the survey contains 1294 Lyman-break candidates, in agreement with previous measurements by other authors. Based on comparisons with spectroscopic observations and simulations, we estimate that our sample of Lyman-break galaxies is contaminated by stars and interlopers at no more than ~30%. We find that \omega(\theta) is well fitted by a power-law of fixed slope, \gamma=1.8, even at small (\theta<10'') angular separations. In two of our three fields, we are able to fit simultaneously for both the slope and amplitude and find a slope \gamma ~ 1.81. Our data marginally indicates in one field (at a 3 \sigma level) that the Lyman-break correlation length r_0 depends on sample limiting magnitude: brighter Lyman-break galaxies are more clustered than fainter ones. For the entire CFDF sample, assuming a fixed slope \gamma = 1.8 we find r_0 = (5.9\pm0.5)h^{-1} Mpc. Using these clustering measurements and prediction for the dark matter density field, we derive a linear bias of b = 3.5 +/- 0.3. Finally we show that the dependence of the correlation length with the surface density of Lyman-break galaxies is in good agreement with a simple picture where more luminous galaxies are hosted by more massive dark matter halos with a simple one-to-one correspondence.Comment: 18 pages including 11 postscript figures. Accepted to A&

Monte Carlo simulation of virtual Compton scattering below pion threshold

This paper describes the Monte Carlo simulation developed specifically for the VCS experiments below pion threshold that have been performed at MAMI and JLab. This simulation generates events according to the (Bethe-Heitler + Born) cross section behaviour and takes into account all relevant resolution-deteriorating effects. It determines the `effective' solid angle for the various experimental settings which are used for the precise determination of photon electroproduction absolute cross section.Comment: 24 pages, 6 figures, to be published in Nuclear Instruments and Methods in Physics Research, A One author adde

The transcriptional activator Gli2 modulates T-cell receptor signalling through attenuation of AP-1 and NFκB activity

Different tissues contain diverse and dynamic cellular niches, providing distinct signals to tissue-resident or migratory infiltrating immune cells. Hedgehog (Hh) proteins are secreted inter-cellular signalling molecules, which are essential during development and are important in cancer, post-natal tissue homeostasis and repair. Hh signalling mediated by the Hh-responsive transcription factor Gli2 also has multiple roles in T-lymphocyte development and differentiation.Here, we investigate the function of Gli2 in T-cell signalling and activation. Gene transcription driven by the Gli2 transcriptional activator isoform (Gli2A) attenuated T-cell activation and proliferation following T-cell receptor (TCR) stimulation. Expression of Gli2A in T-cells altered gene expression profiles, impaired the TCR-induced Ca2+ flux and nuclear expression of NFAT2, suppressed upregulation of molecules essential for activation, and attenuated signalling pathways upstream of the AP-1 and NFκB complexes, leading to reduced activation of these important transcription factors. Inhibition of physiological Hh-dependent transcription increased NFκB activity upon TCR ligation. These data are important for nderstanding the molecular mechanisms of immunomodulation, particularly in tissues where Hh proteins or other Gli-activating ligands such as TGFβ are upregulated, including during inflammation, tissue damage and repair, and in tumour microenvironments

High-precision multi-band measurements of the angular clustering of X-ray sources

In this paper we present the two-point angular correlation function of the X-ray source population of 1063 XMM-Newton observations at high Galactic latitudes, comprising up to ~30000 sources over a sky area of 125.5 sq. deg, in three energy bands: 0.5-2 (soft), 2-10 (hard), and 4.5-10 (ultrahard) keV. We have measured the angular clustering of our survey and find significant positive clustering signals in the soft and hard bands, and a marginal clustering detection in the ultrahard band. We find dependency of the clustering strength on the flux limit and no significant differences in the clustering properties between sources with high hardness ratios and those with low hardness ratios. Our results show that obscured and unobscured objects share similar clustering properties and therefore they both reside in similar environments, in agreement with the unified model of AGN. We deprojected the angular clustering parameters via Limber's equation to compute their typical spatial lengths. From that we have inferred the typical mass of the dark matter haloes in which AGN at redshifts of ~1 are embedded. The short AGN lifetimes derived suggest that AGN activity might be a transient phase that can be experienced several times by a large fraction of galaxies throughout their lives.Comment: 14 pages, 9 figures, accepted for publication in Astronomy and Astrophysic

Clustering properties of galaxies selected in stellar mass: Breaking down the link between luminous and dark matter in massive galaxies from z=0 to z=2

We present a study on the clustering of a stellar mass selected sample of 18,482 galaxies with stellar masses M*>10^10M(sun) at redshifts 0.4<z<2.0, taken from the Palomar Observatory Wide-field Infrared Survey. We examine the clustering properties of these stellar mass selected samples as a function of redshift and stellar mass, and discuss the implications of measured clustering strengths in terms of their likely halo masses. We find that galaxies with high stellar masses have a progressively higher clustering strength, and amplitude, than galaxies with lower stellar masses. We also find that galaxies within a fixed stellar mass range have a higher clustering strength at higher redshifts. We furthermore use our measured clustering strengths, combined with models from Mo & White (2002), to determine the average total masses of the dark matter haloes hosting these galaxies. We conclude that for all galaxies in our sample the stellar-mass-to-total-mass ratio is always lower than the universal baryonic mass fraction. Using our results, and a compilation from the literature, we furthermore show that there is a strong correlation between stellar-mass-to-total-mass ratio and derived halo masses for central galaxies, such that more massive haloes contain a lower fraction of their mass in the form of stars over our entire redshift range. For central galaxies in haloes with masses M(halo)>10^13M(sun) we find that this ratio is <0.02, much lower than the universal baryonic mass fraction. We show that the remaining baryonic mass is included partially in stars within satellite galaxies in these haloes, and as diffuse hot and warm gas. We also find that, at a fixed stellar mass, the stellar-to-total-mass ratio increases at lower redshifts. This suggests that galaxies at a fixed stellar mass form later in lower mass dark matter haloes, and earlier in massive haloes. We interpret this as a "halo downsizing" effect, however some of this evolution could be attributed to halo assembly bias.Comment: Accepted for publication in MNRAS. 19 pages, 8 figures and 3 tables

Pneumococcal carriage in sub-Saharan Africa--a systematic review.

BACKGROUND: Pneumococcal epidemiology varies geographically and few data are available from the African continent. We assess pneumococcal carriage from studies conducted in sub-Saharan Africa (sSA) before and after the pneumococcal conjugate vaccine (PCV) era. METHODS: A search for pneumococcal carriage studies published before 2012 was conducted to describe carriage in sSA. The review also describes pneumococcal serotypes and assesses the impact of vaccination on carriage in this region. RESULTS: Fifty-seven studies were included in this review with the majority (40.3%) from South Africa. There was considerable variability in the prevalence of carriage between studies (I-squared statistic = 99%). Carriage was higher in children and decreased with increasing age, 63.2% (95% CI: 55.6-70.8) in children less than 5 years, 42.6% (95% CI: 29.9-55.4) in children 5-15 years and 28.0% (95% CI: 19.0-37.0) in adults older than 15 years. There was no difference in the prevalence of carriage between males and females in 9/11 studies. Serotypes 19F, 6B, 6A, 14 and 23F were the five most common isolates. A meta-analysis of four randomized trials of PCV vaccination in children aged 9-24 months showed that carriage of vaccine type (VT) serotypes decreased with PCV vaccination; however, overall carriage remained the same because of a concomitant increase in non-vaccine type (NVT) serotypes. CONCLUSION: Pneumococcal carriage is generally high in the African continent, particularly in young children. The five most common serotypes in sSA are among the top seven serotypes that cause invasive pneumococcal disease in children globally. These serotypes are covered by the two PCVs recommended for routine childhood immunization by the WHO. The distribution of serotypes found in the nasopharynx is altered by PCV vaccination

Masses of high-z galaxy hosting haloes from angular clustering and their evolution in the CDM model

We examine masses of hosting haloes of two photometrically-selected high-z galaxy samples: the old passively-evolving galaxies (OPEGs) and Lyman Break Galaxies (LBGs) both taken from the Subaru/XMM-Newton Deep Survey (SXDS). The large survey area of the SXDS (1sq deg) allows us to measure the angular two-point correlation functions to a wide separation of >10 arcmin with a good statistical quality. We utilize the halo model prescription for estimating characteristic masses of hosting haloes from the measured large-scale clustering amplitudes. It is found that the hosting halo mass positively correlates with the luminosity of galaxies. Then, adopting the extended Press-Schechter model (EPS), we compute the predictions for the mass evolution of the hosting haloes in the framework of the cold dark matter (CDM) cosmology in order to make an evolutionary link between the two galaxy samples at different redshifts and to identify their present-day descendants by letting their haloes evolve forward in time. It is found that, in the view of the mass evolution of hosting haloes in the CDM model, bright LBGs are consistent with being the progenitor of the OPEGs, whereas it is less likely that the LBG population, as a whole, have evolved into the OPEG population. It is also found that the present-day descendants of both the bright LBGs and OPEGs are likely to be located in massive systems such as groups of galaxies or clusters of galaxies. Finally, we estimate the hosting halo mass of local early-type galaxy samples from the 2dF and SDSS based on the halo model and it turns out that their expected characteristic mass of hosting haloes is in good agreement with the EPS predictions for the descendant's mass of both the bright LBGs and OPEGs.Comment: 10 pages, 10 figures, submitted to MNRAS. Fortran programs used to compute the model predictions in this paper are available at http://optik2.mtk.nao.ac.jp/~hamanatk/OPENPRO/index.htm