608 research outputs found

    DESEMPENHO ACADÊMICO DOS ALUNOS DE CIÊNCIAS CONTÁBEIS DA FACC/UFRJ: UMA ABORDAGEM PRELIMINAR DO MODELO DE VICENT TINTO

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    A proposta deste estudo é o de analisar o desempenho dos alunos matriculados no ensino superior em função do tempo de conclusão de curso e na comparação das notas obtidas no Exame Nacional do Ensino Médio (ENEM) e o coeficiente de rendimento (CR) entre alunos cotistas e não cotistas. Para isto, foi selecionada uma amostra de alunos ingressantes no período de 2015-2017 no Curso de Ciências Contábeis e que tenham concluído o curso, comparando-se as notas de entrada pelo ENEM com o coeficiente final de rendimento (CR). Os resultados alcançados pela amostra selecionada de 205 egressos demonstram que, apesar de existirem diferenças significantes nas médias de ampla concorrência e cotistas em algumas disciplinas de acesso ao ENEM, tal diferença é dissipada ao comparar os coeficientes de rendimento finais dos concluintes. Também não foram verificadas relações entre as notas do ENEM e os coeficientes de rendimentos de ambos os clusters estudados. Estes resultados corroboram com o Modelo de Vicent Tinto que valoriza grau de integração do estudante no sistema social e acadêmico da instituição

    Production of Hydrogen and their Use in Proton Exchange Membrane Fuel Cells

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    This work will show an overview of the hydrogen production from ethanol by steam reforming method, using distinct catalysts, resulting in low carbon monoxide content in H2 produced; a thermodynamic analysis of reforming employing entropy maximization, the ideal condition for ethanol, and other steam reforming reactions, the state of the art of steam reforming catalysts for H2 production with low CO content. Moreover, in the second part, there will be an overview of the use of hydrogen in a proton exchange membrane fuel cell (PEMFC), the fuel cell operational conditions, a thermodynamic analysis of PEMFC, the catalysts used in the electrodes of the fuel cell, consequences of the CO presence in the hydrogen fuel feed in PEMFC, and the operation conditions for maximum output power density

    Prevention of hypertension in patients with pre-hypertension: protocol for the PREVER-prevention trial

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    <p>Abstract</p> <p>Background</p> <p>Blood pressure (BP) within pre-hypertensive levels confers higher cardiovascular risk and is an intermediate stage for full hypertension, which develops in an annual rate of 7 out of 100 individuals with 40 to 50 years of age. Non-drug interventions to prevent hypertension have had low effectiveness. In individuals with previous cardiovascular disease or diabetes, the use of BP-lowering agents reduces the incidence of major cardiovascular events. In the absence of higher baseline risk, the use of BP agents reduces the incidence of hypertension. The PREVER-prevention trial aims to investigate the efficacy, safety and feasibility of a population-based intervention to prevent the incidence of hypertension and the development of target-organ damage.</p> <p>Methods</p> <p>This is a randomized, double-blind, placebo-controlled clinical trial, with participants aged 30 to 70 years, with pre-hypertension. The trial arms will be chlorthalidone 12.5 mg plus amiloride 2.5 mg or identical placebo. The primary outcomes will be the incidence of hypertension, adverse events and development or worsening of microalbuminuria and of left ventricular hypertrophy in the EKG. The secondary outcomes will be fatal or non-fatal cardiovascular events: myocardial infarction, stroke, heart failure, evidence of new sub-clinical atherosclerosis, and sudden death. The study will last 18 months. The sample size was calculated on the basis of an incidence of hypertension of 14% in the control group, a size effect of 40%, power of 85% and P alpha of 5%, resulting in 625 participants per group. The project was approved by the Ethics committee of each participating institution.</p> <p>Discussion</p> <p>The early use of blood pressure-lowering drugs, particularly diuretics, which act on the main mechanism of blood pressure rising with age, may prevent cardiovascular events and the incidence of hypertension in individuals with hypertension. If this intervention shows to be effective and safe in a population-based perspective, it could be the basis for an innovative public health program to prevent hypertension in Brazil.</p> <p>Trial Registration</p> <p>Clinical Trials <a href="http://www.clinicaltrials.gov/ct2/show/NCT00970931">NCT00970931</a>.</p

    A GESTÃO NO PÓS-PANDEMIA (CRÍTICAS E PERSPECTIVAS): REGISTROS DAS LIVES DA REDE DE PESQUISA EM ADMINISTRAÇÃO POLÍTICA (RPAP )

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    A Rede de Pesquisa em Administração Política convidou alguns especialistas de diferentes áreas da administração para expressar suas opiniões sobre o papel da gestão no pós-Covid-19. Para tanto foi produzida   uma série de nove lives exibida na plataforma do YouTube. As lives buscaram compreender questões como:  qual o futuro do capitalismo, do Estado, do mercado?   É possível taxar as grandes fortunas?  Os atuais modelos de gestão darão conta de responder às demandas sociais futuras? Como ficarão as relações público-privadas no pós-pandemia? O que pode mudar nas relações de trabalho, produção, distribuição e consumo da sociedade pós-pandêmica? O resultado dessas reflexões foi registrado neste documento e nos revela que não podemos voltar à normalidade. O normal é o que nos conduziu ao caos, a uma tripla crise do capitalismo evidenciada na crise   pandêmica, econômica e climática.DOI: 10.53706/gep.v.21.686

    Intersetorialidade e política pública: os resíduos sólidos urbanos em Castanhal - PA / Intersectoriality and public policy: urban solid waste in Castanhal - PA

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    O objetivo desta pesquisa é analisar a intersetorialidade das secretariais vinculadas ao saneamento básico no município de Castanhal-PA e a problemática do vazadouro a céu aberto. A obtenção dos dados primários referentes intersetorialidade, necessários para a realização da pesquisa, ocorreu por meio de visitas às secretarias direta e indiretamente envolvidos no saneamento básico do município para a aplicação de formulários semiestruturados: Secretaria Municipal de Meio Ambiente (SEMMA), Secretaria Municipal de Obras (SEMOB), Vigilância Sanitária (VISA), Secretaria de Saúde  (SSA), Secretaria de Planejamento Urbano (SPU), para levantamento de informações quanto a gestão e gerenciamento de RS em Castanhal-PA. Os dados obtidos indicaram, dentre as secretarias amostradas, apenas a SEMOB tem conhecimento do tempo de funcionamento do vazadouro. Todas as secretarias estão cientes da ilegalidade na utilização da área, que se dá pela ausência de licenciamento e forma inadequada de disposição final dos RSU. Além disso, não há conhecimento por 100% da amostragem sobre a delimitação da área e nem esclarecimentos sobre a expansão e utilização de novas áreas, demostrando que este procedimento é aleatório e ausente de critérios técnicos, dificultando uma ação das secretarias. Um dos principais fatores que corrobora para este entrave é a ausência do Plano Municipal de Gestão Integrada dos RSU (PMGIRS). Os dados obtidos junto às secretarias amostradas indicaram que não existem cooperativas, empresas recicladoras ou organizações de catadores em parceria com as secretarias para atuação na área do vazadouro a céu aberto. Também não há elaboração, acompanhamento, avaliação e atualização do Plano Diretor municipal. A problemática inerente a intersetorialidade no município de Castanhal-PA, está diretamente relacionada a atuação específica de cada secretaria sem articulação em conjunto com as demais. Tal fato é justificado pela fragmentação e distanciamento entre as unidades amostradas, o que dificulta o processo intersetorial e atenua o problema relacionados aos RS no município, elevando os gatos públicos e promovendo entraves socioambientais sem controles.

    Streptococcus canis Are a Single Population Infecting Multiple Animal Hosts Despite the Diversity of the Universally Present M-Like Protein SCM

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    Streptococcus canis is an animal pathogen which occasionally causes infections in humans. The S. canis M-like protein (SCM) encoded by the scm gene, is its best characterized virulence factor but previous studies suggested it could be absent in a substantial fraction of isolates. We studied the distribution and variability of the scm gene in 188 S. canis isolates recovered from companion animals (n = 152), wild animal species (n = 20), and humans (n = 14). Multilocus sequence typing, including the first characterization of wildlife isolates, showed that the same lineages are present in all animal hosts, raising the possibility of extensive circulation between species. Whole-genome analysis revealed that emm-like genes found previously in S. canis correspond to divergent scm genes, indicating that what was previously believed to correspond to two genes is in fact the same scm locus. We designed primers allowing for the first time the successful amplification of the scm gene in all isolates. Analysis of the scm sequences identified 12 distinct types, which could be divided into two clusters: group I (76%, n = 142) and group II (24%, n = 46) sharing little sequence similarity. The predicted group I SCM showed extensive similarity with each other outside of the N-terminal hypervariable region and a conserved IgG binding domain. This domain was absent from group II SCM variants found in isolates previously thought to lack the scm gene, which also showed greater amino acid variability. Further studies are necessary to elucidate the possible host interacting partners of the group II SCM variants and their role in virulence

    Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

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    The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

    Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

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    Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

    Impacts of the Tropical Pacific/Indian Oceans on the Seasonal Cycle of the West African Monsoon

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    The current consensus is that drought has developed in the Sahel during the second half of the twentieth century as a result of remote effects of oceanic anomalies amplified by local land–atmosphere interactions. This paper focuses on the impacts of oceanic anomalies upon West African climate and specifically aims to identify those from SST anomalies in the Pacific/Indian Oceans during spring and summer seasons, when they were significant. Idealized sensitivity experiments are performed with four atmospheric general circulation models (AGCMs). The prescribed SST patterns used in the AGCMs are based on the leading mode of covariability between SST anomalies over the Pacific/Indian Oceans and summer rainfall over West Africa. The results show that such oceanic anomalies in the Pacific/Indian Ocean lead to a northward shift of an anomalous dry belt from the Gulf of Guinea to the Sahel as the season advances. In the Sahel, the magnitude of rainfall anomalies is comparable to that obtained by other authors using SST anomalies confined to the proximity of the Atlantic Ocean. The mechanism connecting the Pacific/Indian SST anomalies with West African rainfall has a strong seasonal cycle. In spring (May and June), anomalous subsidence develops over both the Maritime Continent and the equatorial Atlantic in response to the enhanced equatorial heating. Precipitation increases over continental West Africa in association with stronger zonal convergence of moisture. In addition, precipitation decreases over the Gulf of Guinea. During the monsoon peak (July and August), the SST anomalies move westward over the equatorial Pacific and the two regions where subsidence occurred earlier in the seasons merge over West Africa. The monsoon weakens and rainfall decreases over the Sahel, especially in August.Peer reviewe

    Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

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    A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV
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