Antibacterial Screening of Some Newly Synthesized Cinnamo Hydroxamic Acids

Newly synthesized cinnamo hydroxamic acids (CHA), N-methyl cinnamo hydroxamic acid (MCHA), N-benzyl cinnamo hydroxamic acid (N-BCHA), p-methyl benzyl cinnamo hydroxamic acid (p-CH3BCHA) and p-chloro benzyl cinnamo hydroxamic acid (p-ClBCHA), were synthesized and characterized by 1HNMR, IR spectroscopy and elemental analysis. These compounds are shows bacteristatic and bactericidal properties by the interaction of bacterial cell wall with two process bacterial cell wall synthesis inhibitors and disruption of protein synthesis. The bacterial cell growth zone of inhibition by these compounds (CHA, MCHA, N-BCHA, p-CH3BCHA, p-ClBCHA) for Lactobacillus are 13 mm, 17 mm, 14 mm, 15 mm, 22 mm and for Escherichia coli are 14 mm, 16 mm, 19 mm, 12 mm, 20 mm, at 1000 ppm respectively. Detailed analysis shows that these compounds are good cell growth of inhibition by the study of antibacterial activity against Lactobacillus and Escherichia coli bacteria. Keywords: Cinnamo hydroxamic acids, Antibacterial, Inhibition, Bacterial, Activity

Spectrophotometric Determination of Vanadium (V) Using N–Methyl Cinnamo Hydroxamic Acid as Reagent

The subject of this research is to study the possibility of novel, rapid highly sensitive and selective spectrphotometric method was proposed for the determination of vanadium (V) using N- methyl cinnamo hydroxamic acid (N-MCHA) as a reagent. The method was based on the formation of purple coloured complex between N–methyl cinnamo hydroxamic acid and vanadium (V). The optimum conditions for the determination were established. The Beer’s law is obeyed for vanadium (V) in the concentration range to 0.2-10.0µg/ml at the maximum absorbance at 480nm. In this method molar absorptivity, Sand ell’s sensitivity, detection limit and quantization limit were reported. The proposed method free from over a wide variety of cations, anions, and complexion interference species. This method was successfully applied to the analysis of vanadium (V) in water, soil, urine, steel and pharmaceutical samples. Keywords: Vanadium (V), N-methyl cinnamo hydroxamic acid, Absorptivity, Complexion

Uncatalysed Oxidation of Dextrose by Cerium(IV) in Aqueous Acidic Medium-A Kinetic and Mechanistic Study

Abstract A Kinetics investigation of uncatalysed oxidation of dextrose by cerium (IV

Ayurveda Kayachikitsa towards the management of joint pain: a review

Joint pain is one of the very common problems amongst the elderly age population. Clinically it is characterized by shula, shotha and prasaarana-aakunchanayo pravruttischa vedana. Ayurveda described various treatment modalities for the management of joint pain such as; snehana, swedan, upanaha, lepa and herbal medicine. Kayachikitsa is branch which deal with use of ayurveda drugs for the management of various diseases. This branch also recommended use of different natural medicine for the treatment of joint pain. Guggulu (Comiphora mukul) is most common drug used in Amavata; disease of joint pain. Similarly various herbal formulation of Ashwagandha, Rasna, Sunthi, Pippali, Gokshura and Trivrut are also recommended in diseases of joint pain. Present article summarized role of herbal medicine in joint pain. Keywords: Ayurveda, Kayachikitsa, Joint Pain, Shula, Vedana.   &nbsp

Kinetic and mechanistic study of acid-catalysed hydrolysis of 3-chlorobenzohydroxamic acid

139-142The rate of hydrolysis of 3-chlorobenzohydroxamic acid [3-Cl-C6H4.CO.NHOH] has been measured over a wide range of acidities in hydrochloric, sulfuric and perchloric acids in 10% (v/v) DMSO-Water at 55oC. The kinetics have been analysed by Bunnett, Bunnett-Olsen and Cox-Yates excess acidity treatments. Kinetic solvent isotope, salt and temperature effects have also been probed. The mechanism of the acid catalysed hydrolysis is postulated as involving two steps: a rapid protonation and a rate-determining A-2 nucleophilic attack by water

Dipotassium terephthalate as promising potassium storing anode with DFT calculations

We report combined experimental and theoretical studies of dipotassium terephthalate as anode material for K-ion battery application. Both pristine and carbon nanotube-containing dipotassium terephthalate materials are synthesized using an ultrafast microwave-assisted method. We found that carbon nanotube (CNT)-containing dipotassium terephthalate composite electrode delivers an initial reversible capacity of 247 mAh/g with 78% capacity retention, whereas pristine K2Tp deliveries an initial reversible capacity of 212 mAh/g with 53% capacity retention at the end of 100 cycles, at a current density of 50 mA/g. The density functional theory-based calculations have shown superior stability of dipotassium terephthalate lattice against the intercalation of potassium atoms. The quantum calculations are also employed to unravel the specifics of intercalation energetics of potassium ions into dipotassium terephthalate lattice. The intercalation and de-intercalation potentials of K-ions are obtained using cyclic voltammetry and compared with theoretical calculations under the assumption of a two-electron transfer reaction. The results of this study lay the ground for understanding the electrochemical processes involved in the operation of an organic anode in K-ion batteries, and thereby can facilitate the design of optimal organic molecular crystal-based electrode materials for battery applications