1,662 research outputs found
Psychosocial profile in portuguese adolescents with chronic disease attending an outpatient department in a hospital setting
Living with a chronic disease (CD) in adolescence involves new multifaceted challenges. This study aims to conduct a psychosocial characterization of a group of adolescents with chronic diseases in a hospital setting and to compare such dimensions for the total group and for different diseases. A cross-sectional study included 135 adolescents with chronic diseases (51.9% boys; 48.1% girls), having an average age of 14±1.5 years (SD=1.5) and attending a paediatric outpatient department in a hospital setting. Statistically significant differences were found among the different chronic diseases for the variables self-regulation (adolescents with diabetes had significantly higher competencies) and multiple psychosomatic symptoms (adolescents with neurologic diseases reported significantly more complaints). Boys presented both better health-related quality of life and psychosomatic health when compared to girls. No statistically significant differences were observed for health-related quality of life, psychosomatic health, resilience, and social support. These findings bring important suggestions especially while planning interventions, which must take into account the promotion of a healthy psychosocial development, through an inclusive perspective (covering different chronic diseases), that take into consideration specific and gendered approaches. Such suggestions might help healthcare professionals to better plan interventions in order to increase their effectiveness.Fundação para a CiĂȘncia e a Tecnologia - FCTinfo:eu-repo/semantics/publishedVersio
Adolescentâs subjective perceptions of chronic disease and related psychosocial factors: Highlights from an outpatient context study
Background: Adolescents with chronic disease (CD) can be more vulnerable to adverse psychosocial outcomes.
This study aims: 1) to identify differences in psychosocial variables (health-related quality of life, psychosomatic
complaints, resilience, self-regulation and social support) among adolescents who feel that CD affects or does not
affect school/peers connectedness (measured by self-reported participation in school and social activities); and 2) to
assess the extent to which psychosocial variables are associated with connectedness in school and peer domains.
Methods: A cross-sectional study was conducted in 135 adolescents with CD (51.9% boys), average age of 14 ± 1.
5 years old (SD = 1.5). Socio-demographic, clinical, and psychosocial variables were assessed, using a self-reported
questionnaire, which included the Chronic Conditions Short Questionnaire, KIDSCREEN-10 Index, Symptoms
Check-List, Healthy Kids Resilience Assessment Module Scale, Adolescent Self-Regulatory Inventory, and Satisfaction
with Social Support Scale. Descriptive statistics, GLM-Univariate ANCOVA and Logistic Regression were performed
using the IBM Statistical Package for Social Sciences (SPSS), version 22.0. The significance level was set at p < 0.05.
Results: Thirteen to eighteen percent of the adolescents felt that CD affected participation at school (PSCH) and
participation in leisure time with friends (PLTF). These adolescents presented lower results for all psychosocial study
variables, when compared with adolescents who did not feel affected in both areas of participation. From the
studied psychosocial variables, the most important ones associated with PSCH (after controlling for age, gender,
diagnosis, and education level of father/mother) were self-regulation and psychosomatic health. Concerning the
PLTF, social support was the sole variable explaining such association. Conclusions: The present study pointed out the association between psychosocial variables; and living with a CD
and school/peers connectedness. The need to focus on the assessment of the effects of a CD on adolescentsâ lives
and contexts is suggested, as well as on the identification of vulnerable adolescents. Such identification could help
to facilitate the maximization of social participation of adolescents with CD, and to plan interventions centered on
providing support and opportunities for a healthy youth development. For that purpose, a complex and multifactorial
approach that includes clinicians, schools, family, and peers may be proposed.Fundação para a CiĂȘncia e a tecnologia (FCT)info:eu-repo/semantics/publishedVersio
Artistas sobre outras Obras
Entre a pele da pintura e a pele do pintor, existe uma continuidade interrompida pelo encerramento da peça, em que o autor se despede e abre caminho aos novos participantes. Estes sĂŁo seres polĂticos, pois sĂŁo pĂșblico, sĂŁo relação. As quinze propostas de abordagem Ă obra de outros tantos artistas que aqui sĂŁo apresentadas, neste nĂșmero 35 da Revista EstĂșdio, transportam um desejo interior de uma expansĂŁo para os vivos, para novas relaçÔes, novos trĂąnsitos, no cĂrculo aberto das artesinfo:eu-repo/semantics/publishedVersio
Complexity and relevance for health and behavior
Acknowledgments: Gina TomĂ© is a postdoctorate funded by the Fundação CiĂȘncia e Tecnologia (FCT) SFRH/BPD/108637/2015.Objective: The aim of this study was to evaluate sleep and awakening quality (SQ and AQ) during COVID-19 in a large and diversified population in order to identify significant associations and risks in terms of demography, health and health-related behaviors, sleep variables, mental health, and attitudes. Methods/Results:Online surveys were used for data collection, received from 5479 individuals from the general population, sleep disorder patients, and COVID-involved (medical doctors (MDs) and nurses) and COVID-affected professionals (teachers, psychologists, and dentists). SQ and AQ were worse in adults, females, and high-education subjects. Feeling worse, having economic problems, depression, anxiety, irritability, and a high Calamity Experience Check List (CECL) score during COVID were significantly associated with poor SQ and AQ. Shorter sleep duration, increased latency, poor nutrition, low physical activity, increased mobile and social network use, more negative and less positive attitudes and behaviors were associated with poor AQ. Conclusions: The SQ logistic regression showed gender, morbidities, CECL, and awakenings as relevant, whereas, for AQ, relevant variables further included age and physical activity. Aiming to have a high stress compliance, each individual should sleep well, have important control of their mood, practice positive behaviors while dismissing negative behaviors and attitudes, practice exercise, have adequate nutrition, and beware of technologies and dependences.publishersversionpublishe
A comprehensive assessment of the transcriptome of cork oak (Quercus suber) through EST sequencing
Background: Cork oak (Quercus suber) is one of the rare trees with the ability to produce cork, a material widely used to make wine bottle stoppers, flooring and insulation materials, among many other uses. The molecular mechanisms of cork formation are still poorly understood, in great part due to the difficulty in studying a species with a long life-cycle and for which there is scarce molecular/genomic information. Cork oak forests are of great ecological importance and represent a major economic and social resource in Southern Europe and Northern Africa. However, global warming is threatening the cork oak forests by imposing thermal, hydric and many types of novel biotic stresses. Despite the economic and social value of the Q. suber species, few genomic resources have been developed, useful for biotechnological applications and improved forest management.
Results: We generated in excess of 7 million sequence reads, by pyrosequencing 21 normalized cDNA libraries derived from multiple Q. suber tissues and organs, developmental stages and physiological conditions. We deployed a stringent sequence processing and assembly pipeline that resulted in the identification of ~159,000 unigenes. These were annotated according to their similarity to known plant genes, to known Interpro domains, GO classes and E.C. numbers. The phylogenetic extent of this ESTs set was investigated, and we found that cork oak revealed a significant new gene space that is not covered by other model species or EST sequencing projects. The raw data, as well as the full annotated assembly, are now available to the community in a dedicated web portal at http://www.corkoakdb.org.
Conclusions: This genomic resource represents the first trancriptome study in a cork producing species. It can be explored to develop new tools and approaches to understand stress responses and developmental processes in forest trees, as well as the molecular cascades underlying cork differentiation and disease response.Peer Reviewe
Estudos ArtĂsticos
Arte: ativar o humano. Dentro do desafio do âCongresso CSO, Criadores Sobre outras Obras,ââ em que artistas sĂŁo chamados a escrever sobre a obra de outros artistas, no Ăąmbito dos paĂses de lĂngua portuguesa ou espanhola, â a Revista Croma interessa-se pelas instĂąncias de intervenção, implicação, aproximação junto das comunidades, de excluĂdos, de comunidades menos diferenciadas. HĂĄ um vasto campo de ação onde tĂȘm surgido movimentos para novas relaçÔes, conhecimentos, atitudes e prĂĄticas. Se a dimensĂŁo relacional tem vindo a ser problematizada com maior insistĂȘncia no contexto da crĂtica contemporĂąnea, especialmente na vertente que se debruça sobre o efeito ideolĂłgico do orientalismo e da realidade pĂłs-colonial, entĂŁo os 16 artigos que se alinham nesta edição fornecem leituras alternativas sobre as dinĂąmicas da arte contemporĂąnea. Sobre as relaçÔes sociais tecem-se ligaçÔes intermediadoras. Os seus resultados habitam as cidades, geram novas formas de pensar, renovam discursos, promovem identidade. Trata-se de habitar de novo os espaços vazios, de ativar o humano, que Ă© tambĂ©m onde se podem encontrar as novas formulaçÔes artĂsticas.info:eu-repo/semantics/publishedVersio
SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal
Genomic surveillance of SARS-CoV-2 in Portugal was rapidly implemented by
the National Institute of Health in the early stages of the COVID-19 epidemic, in collaboration
with more than 50 laboratories distributed nationwide.
Methods By applying recent phylodynamic models that allow integration of individual-based
travel history, we reconstructed and characterized the spatio-temporal dynamics of SARSCoV-2 introductions and early dissemination in Portugal.
Results We detected at least 277 independent SARS-CoV-2 introductions, mostly from
European countries (namely the United Kingdom, Spain, France, Italy, and Switzerland),
which were consistent with the countries with the highest connectivity with Portugal.
Although most introductions were estimated to have occurred during early March 2020, it is
likely that SARS-CoV-2 was silently circulating in Portugal throughout February, before the
first cases were confirmed.
Conclusions Here we conclude that the earlier implementation of measures could have
minimized the number of introductions and subsequent virus expansion in Portugal. This
study lays the foundation for genomic epidemiology of SARS-CoV-2 in Portugal, and highlights the need for systematic and geographically-representative genomic surveillance.We gratefully acknowledge to Sara Hill and Nuno Faria (University of Oxford) and
Joshua Quick and Nick Loman (University of Birmingham) for kindly providing us with
the initial sets of Artic Network primers for NGS; Rafael Mamede (MRamirez team,
IMM, Lisbon) for developing and sharing a bioinformatics script for sequence curation
(https://github.com/rfm-targa/BioinfUtils); Philippe Lemey (KU Leuven) for providing
guidance on the implementation of the phylodynamic models; Joshua L. Cherry
(National Center for Biotechnology Information, National Library of Medicine, National
Institutes of Health) for providing guidance with the subsampling strategies; and all
authors, originating and submitting laboratories who have contributed genome data on
GISAID (https://www.gisaid.org/) on which part of this research is based. The opinions
expressed in this article are those of the authors and do not reflect the view of the
National Institutes of Health, the Department of Health and Human Services, or the
United States government. This study is co-funded by Fundação para a CiĂȘncia e Tecnologia
and AgĂȘncia de Investigação ClĂnica e Inovação BiomĂ©dica (234_596874175) on
behalf of the Research 4 COVID-19 call. Some infrastructural resources used in this study
come from the GenomePT project (POCI-01-0145-FEDER-022184), supported by
COMPETE 2020 - Operational Programme for Competitiveness and Internationalisation
(POCI), Lisboa Portugal Regional Operational Programme (Lisboa2020), Algarve Portugal
Regional Operational Programme (CRESC Algarve2020), under the PORTUGAL
2020 Partnership Agreement, through the European Regional Development Fund
(ERDF), and by Fundação para a CiĂȘncia e a Tecnologia (FCT).info:eu-repo/semantics/publishedVersio
Artistas sobre outras obras
Sobre arte e viagem pode-se estabelecer um paralelo continuado, irĂłnico, expressivo. Entre as duas, a sĂntese do signo, a justaposição associativa. A viagem mostra o mundo, a viagem mostra quem somos. A caminho se desenha, se imagina, se fantasia, se mente. Neste ensejo, e neste mote da descoberta, se apreentam os 16 artigos que compĂ”em o nĂșmero 26 da revista EstĂșdio.info:eu-repo/semantics/publishedVersio
Differential cross section measurements for the production of a W boson in association with jets in protonâproton collisions at âs = 7 TeV
Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript â1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio
- âŠ