99 research outputs found
Interview with Mr. Stadelman and Birdie Graham
Interviews with Mr. Stadelman and Birdie Graham. This recording is of poor quality and appears to have been recorded over an unidentified T.W. Wells lecture to a folklore class. 00:00:00 - Interview with Mr. Stadelman of Hays, Kansas on January 4, 1964 by Patty Ann Loomis 00:00:32 - Song, Brotlieb on accordion 00:02:15 - Three waltzes on accordion 00:04:35 - Song, Hochzeit on accordion 00:06:26 - Song, The Flying Dutchman on accordion 00:07:24 - Song, Put Your Little Foot on accordion 00:08:47 - Song, Schottische on accordion 00:09:40 - Song, Du, du Liegst mir am Herzen vocal and accordion 00:10:29 - Song, Beer Barrel Polka accordion 00:11:51 - Song, Hochzeit on accordion 00:12:57 - Introduction, interview with Birdie Graham of Dodge City, KS by Ralph Oringer on December 1, 1963 00:13:33 - Life near Old Salem and Abraham Lincoln\u27s log cabin 00:15:33 - Mill on the Solomon River The recording abruptly ends and the remainder is missinghttps://scholars.fhsu.edu/sackett/1091/thumbnail.jp
Effect of NonĂą Surgical Periodontal Therapy on CĂą Telopeptide Pyridinoline CrossĂą Links (ICTP) and InterleukinĂą 1 Levels
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141705/1/jper1045.pd
Relationship between C-telopeptide pyridinoline cross-links (ICTP) and putative periodontal pathogens in periodontitis
Crevicular fluid pyridinoline cross-linked carboxyterminal telopeptide of type 1 collagen (ICTP) is predictive for future alveolar bone loss in experimental periodontitis in dogs. The present study sought to relate ICTP to a panel of subgingival species in subjects exhibiting various clinical presentations such as health ( n = 7), gingivitis ( n = 8) and periodontitis (n=21), 28 subgingival plaque and GCF samples were taken from mesiobuccal sites m each of 36 subjects. The presence and levels of 40 subgtngivai taxa were determined in plaque samples using whole genomic DNA probes and checkerboard DNA-DNA hybridization. GCF ICTP levels were quantified using radioimmunoassay (RIA). Clinical assessments made at the same sites included: BOP, gingival redness, plaque, pocket depth, and attachment level. Differences among ICTP levels in the 3 subject groups were sought using the Kruskal-Wallis test. Relationships between ICTP levels and clinical parameters as well as subgingival species were determined by regression analysis. The results demonstrated significant differences among disease categories for GCF ICTP levels for healthy (1.1+0.6 pg/site (mean±SEM)) gingivitis (14.8±6.6 pg/site) and penodontitts subjects (30.3 + 5.7 pg/site) ( p = 0.0017). ICTP levels related modestly to several clinical parameters. Regression analysis indicated that ICTP levels correlated strongly with mean subject levels of several periodontal pathogens including B. forsythus, P. gingivitis, P. intermedia, P. nigrescens and T. dentcola ( p < 0.01). The data indicate that there is a positive relationship between the putative bone resorptive marker ICTP and periodontal pathogens.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74809/1/j.1600-051X.1998.tb02383.x.pd
Treatment of Periodontitis by Local Administration of Minocycline Microspheres: A Controlled Trial
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141491/1/jper1535.pd
Effects of Monolaurin on Oral Microbe-Host Transcriptome and Metabolome
The aim of this in vitro study was to evaluate the effects of monolaurin against Aggregatibacter actinomycetemcomitans (Aa) and determine their effects on the host transcriptome and metabolome, using an oral cell/bacteria co-culture dual-chamber model to mimic the human periodontium. For this, the Aa, was applied to cross the monolayer of epithelial keratinocytes (OBA-9) to reach the fibroblasts layer (HGF-1) in the basal chamber. The Monolaurin treatments (25 or 50 ĂÂŒM) were added immediately after the inoculation of the dual-chamber with Aa. After 24 h, the transcriptional factors and metabolites produced were quantified in the remaining cell layers (insert and basal chamber) and in supernatant released from the cells. The genes IL-1ñ, IL-6, IL-18, and TNF analyzed in HGF-1 concentrations showed a decreased expression when treated with both concentration of Monolaurin. In keratinocytes, the genes IL-6, IL-18, and TNF presented a higher expression and the expression of IL-1ñ decreased when treated with the two cited concentrations. The production of glycerol and pyruvic acid increased, and the 2-deoxytetronic acid NIST, 4-aminobutyric acid, pinitol and glyceric acid, presented lower concentrations because of the treatment with 25 and/or 50 ĂÂŒM of Monolaurin. Use of monolaurin modulated the immune response and metabolite production when administered for 24 h in a dual-chamber model inoculated with A. actinomycetemcomitans. In summary, this study indicates that monolaurin had antimicrobial activity and modulated the host immune response and metabolite production when administered for 24 h in a dual-chamber model inoculated with A. actinomycetemcomitans
Baicalin Downregulates Porphyromonas gingivalis Lipopolysaccharide-Upregulated IL-6 and IL-8 Expression in Human Oral Keratinocytes by Negative Regulation of TLR Signaling
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Novel Insights into Pituitary Tumorigenesis: Genetic and Epigenetic Mechanisms.
Substantial advances have been made recently in the pathobiology of pituitary tumors. Similar to many other endocrine tumors, over the last few years we have recognized the role of germline and somatic mutations in a number of syndromic or nonsyndromic conditions with pituitary tumor predisposition. These include the identification of novel germline variants in patients with familial or simplex pituitary tumors and establishment of novel somatic variants identified through next generation sequencing. Advanced techniques have allowed the exploration of epigenetic mechanisms mediated through DNA methylation, histone modifications and noncoding RNAs, such as microRNA, long noncoding RNAs and circular RNAs. These mechanisms can influence tumor formation, growth, and invasion. While genetic and epigenetic mechanisms often disrupt similar pathways, such as cell cycle regulation, in pituitary tumors there is little overlap between genes altered by germline, somatic, and epigenetic mechanisms. The interplay between these complex mechanisms driving tumorigenesis are best studied in the emerging multiomics studies. Here, we summarize insights from the recent developments in the regulation of pituitary tumorigenesis
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Spatial Relations: Post-War Reconstruction and the Afterlives of Jewish Terrains in Lebanon
In this dissertation, I contend that, though Lebanon has long been imagined as a haven of diversity in the Middle East, only recently has the countryâs once-flourishing Jewish community been considered by state powers and the public as a representation of local cosmopolitanism. During the Lebanese Civil War (1975-90), Jewish synagogues, neighborhoods, schools, and cemeteries faced the same threats of destruction and abandonment as the greater built environment. Lebanese Jews, who stood at roughly 14,000 in the decade prior to the war, now almost exclusively live in the diaspora. Today, Jewish spaces have been refurbished by developers, repaired by diasporic groups, and adapted to house refugees of Palestinian and Syrian origin. To understand how diverse relationships to the spaces of an absent minority group influence concepts of belonging among the Lebanese body politic, I consider how those interfacing with Jewish sites reflect on their prior histories and articulate their own aspirations through processes of multidirectional memory. The Introduction to the dissertation introduces Lebanon, its Jewish past, and the main questions and research modalities of the dissertation. Chapter One narrativizes Lebanonâs Jewish history within the broader scope of imperial projects and the development of a Lebanese state and national identity. Within this framework, I pay particular attention to the growth of a communal Jewish identity, especially within the scope of the hardening of ethno-religious affiliations into the sole legitimate category of political representation. Chapter Two accounts for the transformation of Wadi Abu JamilâBeirutâs historic Jewish neighborhood and the location of the countryâs only rehabilitated synagogueâvis-a-vis the violent spatial metamorphosis of the surrounding central district since the official cessation of the civil war. I chronicle the process of co-designing a Wadi Abu Jamil walking tour with a Lebanese architect that examined both its Jewish history and its current inaccessibility. In Chapter Three, I focus my analysis on photographs pertaining to Beirutâs historic Jewish neighborhood and its central synagogue. I address the ways in which the mobilization of collective nostalgia through the circulation of these snapshots on three Lebanese Jewish Facebook groups provides a realm for debating, challenging, and reconstructing concepts of belonging as they relate to remembering while remembering a shared homeland from the diaspora. Chapter Four addresses the quotidian transformations of Lebanonâs formerly Jewish neighborhoods, and the ways in which these sites are entangled with varying nationalisms, crises, dislocations, and local political contestations. This chapter draws on ethnographic material from Sidon in order to consider how non-Jewish âcultural brokersââthose who, through voluntary involvement or the happenstance of interacting with/living in formerly Jewish spacesâare charged with the role of interpreting and preserving the histories of these sites. In the dissertation, I assert that these individuals serve as âcultural brokersâ; through voluntary involvement or the happenstance of living in and around formerly Jewish spaces, they interpret and preserve the histories of these sites. I also analyze how political parties and elite state actors mobilize a Lebanese-Jewish past within a narrative that posits a uniquely Lebanese cosmopolitanism as essential to moving beyond ethno-sectarian violence. By examining notions of âJewishnessâ within the post-war state, I show how everyday interactions with the built environment construct discursive and social spaces within which people grapple with notions of social difference. The research for this dissertation was carried out over 21 months of ethnographic fieldwork. My fieldwork combined multiple methodologies in order to contend with the afterlives of Jewish spaces in Lebanon, including life history interviews conducted with interlocutors; numerous semi-structured and informal interviews; research conducted in institutional, private, and nontraditional archives; participant observation and âwebservation;â visits to formerly Jewish sites across Lebanon; and photographic and experimental visual documentation
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