28 research outputs found
The First Post-Kepler Brightness Dips of KIC 8462852
- Author
- Alonso Roi
- Ammerman Alex
- Armstrong David
- Asensio Ramos A.
- Aznar Carbo Miguel
- Barkaoui K.
- Beatty Thomas G.
- Benkhaldoun Z.
- Benni Paul
- Bentley Rory O.
- Berdyugin Andrei
- Berdyugina Svetlana
- Bergeron Serge
- Bieryla Allyson
- Blain Michaela G.
- Bodman Eva H. L.
- Boucher Anne
- Boyajian Tabetha S.
- Bradley Mark
- Brincat Stephen M.
- Brink Thomas G.
- Briol John
- Brown David J. A.
- Budaj J.
- Burdanov Artem
- Cale B.
- Capetillo Blanco Alicia
- Castillo García R.
- Clark Wendy J.
- Clayton Geoffrey C.
- Clem James L.
- Coker Phillip H.
- Cook Evan M.
- Copperwheat Chris M.
- Cseh B.
- Curtis J. L.
- Cutri R. M.
- Cynamon C. H.
- Daniels Alex J.
- Davenport James R. A.
- de Jaeger Thomas
- De Lorenzo Roberto
- Deeg Hans J.
- Desrosiers Jean-Bruno
- Dolan John
- Dowhos D. J.
- Dubois Franky
- Durkee R.
- Dvorak Shawn
- Easley Lynn
- Edwards N.
- Ellis Tyler G.
- Erdelyi Emery
- Ertel Steve
- Farfán Rafael G.
- Farihi J.
- Filippenko Alexei V.
- Foxell Emma
- Gandolfi Davide
- Garcia Faustino
- Giddens F.
- Gillon Michaël
- González Hernández J. I.
- González-Carballo Juan-Luis
- González-Fernández C.
- Graham Keith A.
- Greene Kenton A.
- Gregorio J.
- Hallakoun Na Ama
- Hanyecz Ottó
- Harp G. R.
- Henry Gregory W.
- Herrero E.
- Hildbold Caleb F.
- Hinzel D.
- Holgado G.
- Ignácz Bernadett
- Ilyin Ilya
- Ivanov Valentin D.
- Jehin Emmanuel
- Jermak Helen E.
- Johnston Steve
- Kafka S.
- Kalup Csilla
- Kardasis Emmanuel
- Kaspi Shai
- Kennedy Grant M.
- Kessler Dennis
- Kiefer F.
- Kielty C. L.
- Kiiskinen H.
- Killestein T. L.
- King Ronald A.
- Kollar V.
- Korhonen H.
- Kotnik C.
- Kriskovics Levente
- Krumm Nathan
- Krushinsky Vadim
- Kundra E.
- Könyves-Tóth Réka
- Lachapelle Francois-Rene
- LaCourse D.
- Lake P.
- Lam Kristine
- Lamb Gavin P.
- Lane Dave
- Lau Marie Wingyee
- Lewin Pablo
- Lintott Chris
- Lisse Carey
- Logie Ludwig
- Longeard Nicolas
- Lopez Villanueva M.
- Mainzer A.
- Malo Lison
- Maloney Chris
- Mann A.
- Mantero A.
- Marchant Jon
- Marengo Massimo
- Martínez González M. J.
- Masiero Joseph R.
- Mauerhan Jon C.
- McCormac James
- McNeely Aaron
- Meng Huan Y. A.
- Miller Mike
- Molnar Lawrence A.
- Morales J. C.
- Morris Brett M.
- Muterspaugh Matthew W.
- Nespral David
- Nugent C. R.
- Nugent Katherine M.
- O'Keeffe Derek
- O'Meara John M.
- Odasso A.
- Oksanen A.
- Ordasi András
- Osborn Hugh
- Ott John J.
- Parks J. R.
- Petriew Vance
- Pickard R.
- Plavchan P.
- Pollacco Don
- Pozo Nuñez F.
- Pozuelos Romero Francisco José
- Pál András
- Rau Steve
- Redfield Seth
- Relles Howard
- Ribas Ignasi
- Richards Jon
- Rodriguez Perez Diego
- Saario Joonas L. O.
- Safron Emily J.
- Sallai J. Martin
- Schaefer Bradley E.
- Schumer Clea F.
- Schwartzendruber Madison
- Siegel Michael H.
- Siemion Andrew P. V.
- Simmons Brooke D.
- Simon Joshua D.
- Simón-Díaz S.
- Sitko Michael L.
- Socas-Navarro Hector
- Starkey Donn
- Steele Iain A.
- Stone Geoff
- Strassmeier Klaus G.
- Street R. A.
- Sullivan Tricia
- Suomela J.
- Swift J. J.
- Szabó Gyula M.
- Szabó Róbert
- Szakáts Róbert
- Szalai Tamás
- Sárneczky Krisztián
- Sódor Á.
- Tanner Angelle M.
- Toledo-Padrón B.
- Tordai Tamás
- Triaud Amaury H. M. J.
- Turner Jake D.
- Ulowetz Joseph H.
- Urbanik Marian
- Vanaverbeke Siegfried
- Vanderburg Andrew
- Vida Krisztián
- Vietje Brad P.
- Vinkó József
- von Braun K.
- Waagen Elizabeth O.
- Walsh Dan
- Watson Christopher A.
- Weir R. C.
- Wenzel Klaus
- Westendorp Plaza C.
- Whit Ludington E.
- Williamson Michael W.
- Wright Jason T.
- Wyatt M. C.
- Zheng Weikang
- Zsidi Gabriella
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2018
- Field of study
We present a photometric detection of the first brightness dips of the unique variable star KIC 8462852 since the end of the Kepler space mission in 2013 May. Our regular photometric surveillance started in October 2015, and a sequence of dipping began in 2017 May continuing on through the end of 2017, when the star was no longer visible from Earth. We distinguish four main 1-2.5% dips, named "Elsie," "Celeste," "Skara Brae," and "Angkor", which persist on timescales from several days to weeks. Our main results so far are: (i) there are no apparent changes of the stellar spectrum or polarization during the dips; (ii) the multiband photometry of the dips shows differential reddening favoring non-grey extinction. Therefore, our data are inconsistent with dip models that invoke optically thick material, but rather they are in-line with predictions for an occulter consisting primarily of ordinary dust, where much of the material must be optically thin with a size scale <<1um, and may also be consistent with models invoking variations intrinsic to the stellar photosphere. Notably, our data do not place constraints on the color of the longer-term "secular" dimming, which may be caused by independent processes, or probe different regimes of a single process
Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2
- Author
- Abellán Javier
- Acosta-isaac René
- Aguado Jose María
- Aguilar Carlos
- Aguilera-albesa Sergio
- Ahmadi Sabbagh Abdolah
- Alba Jorge
- Albu Sergiu
- Alcalá-gallardo Karla A. M.
- Alcoba-florez Julia
- Alcolea Batres Sergio
- Algarin-lara Holmes Rafael
- Almadana Virginia
- Almeida Julia
- Almoguera Berta
- Alonso María R.
- Andreu-bernabeu Álvaro
- Antonijoan Maria Rosa
- Arana-arri Eunate
- Aranda Carlos
- Arango Celso
- Araque Carolina
- Araujo Izabel M. T.
- Araujo Nathalia K.
- Arcanjo Ana C.
- Arnaiz Ana
- Arnalich Fernández Francisco
- Arranz María J.
- Arribas López José Ramón
- Artiga Maria-jesús
- Avello-malaver Yubelly
- Ayuso Carmen
- Balagué-dobón Laura
- Baldion Ana María
- Ballina Martín Belén
- Baptista-rosas Raúl C.
- Barranco-díaz Andrea
- Barreda-sánchez María
- Barrera-penagos Viviana
- Belhassen-garcia Moncef
- Bernal Enrique
- Bernal-bello David
- Bezerra Joao F.
- Bezerra Marcos A. C.
- Blanca-lópez Natalia
- Blancas Rafael
- Boix-palop Lucía
- Borobia Alberto
- Bravo Elsa
- Brion María
- Brochado-kith Óscar
- Brugada Ramón
- Bustos Matilde
- Cabello Alfonso
- Calbo Esther
- Calderón Enrique J.
- Camacho Shirley
- Campos Marcela C.
- Carbonell Cristina
- Cardona-huerta Servando
- Carioca Antonio Augusto F.
- Carpio Segura Carlos
- Carracedo Ángel
- Carratto Thássia M. T.
- Carrillo-avila José Antonio
- Carvalho Maria C. C.
- Casasnovas Carlos
- Castaño Carlos F.
- Castaño Luis
- Castelao Jose E.
- Castellano Candalija Aranzazu
- Castillo María A.
- Cañadas Yolanda
- Ceballos Francisco C.
- Chaux Jessica G.
- Chaves-santiago Walter G.
- Chiquillo-gómez Sylena
- Cid-lópez Marco A.
- Cienfuegos-jiménez Óscar
- Conde-vicente Rosa
- Cordero-lorenzana M. Lourdes
- Corella Dolores
- Corrales Almudena
- Corton Marta
- Cortés-sánchez Jose L.
- Costa Tatiana X.
- Cruz Marina S.
- Cruz Raquel
- Cuesta Luisa
- Cunha Gabriela C. R.
- Cáceres Alejandro
- Cáceres-agra Juan J.
- Dalmau David
- Dantas-komatsu Raquel C. S.
- Darnaude M. Teresa
- De Andrés Raimundo
- De Araújo Jéssica N. G.
- De Juan Carmen
- De La Cruz Troca Juan J.
- De La Horra Carmen
- De La Hoz Ana B.
- De Martino-rodríguez Alba
- De Sousa Alves Neri Julianna Lys
- Del Campo-pérez Victor
- Delgado-cuesta Juan
- Diaz De Bustamante Aranzazu
- Dietl Beatriz
- Diz-de Almeida Silvia
- Do Monte Alves Manoella
- Domínguez-garrido Elena
- Dos Santos Katiusse A.
- Duarte Alice L.
- Díaz-caneja Covadonga M.
- Díaz-pérez Anderson
- Echave-sustaeta Jose
- Eiros Rocío
- Enciso-olivera César O.
- Escudero Gabriela
- Esko Tonu
- España Pedro Pablo
- Estigarribia Sanabria Gladys
- Fariñas María Carmen
- Fernandes Marianne R.
- Fernandez-nestosa María J.
- Fernández Martínez Yolanda
- Fernández Ramón
- Fernández Ruth
- Fernández-caballero Lidia
- Fernández-capitán Carmen
- Fernández-cruz Ana
- Fernández-ferrero Silvia
- Fernández-robelo Uxía
- Fernández-rodríguez Amanda
- Fernández-sampedro Marta
- Fernández-villa Tania
- Flores Carlos
- Flores-pérez Patricia
- Friaza Vicente
- Fuenmayor-hernández Lácides
- Fuertes-núñez Marta
- Fumadó Victoria
- Gadea Ignacio
- Gagliardi Lidia
- Gago-domínguez Manuela
- Gallego Natalia
- Galoppo Cristina
- Garcia-garcía Josefina
- García Torrejón María Carmen
- García Inés
- García Leticia
- García Mercedes
- García-cerrada Carlos
- García-de-vicuña Aitor
- García-garcía Irene
- García-ibarbia Carmen
- García-montero Andrés C.
- García-soidán Ana
- García-vázquez Elisa
- Garza-frias Emiliano
- Gentile Angela
- Gil-fournier Belén
- Gonzalez-sagrado Manuel
- Gonzalo-benito Hugo
- González Bernaldo De Quirós Fernán
- González Álvarez Beatriz
- González Juan R.
- González Juan R.
- González-montelongo Rafaela
- González-neira Anna
- González-peñas Javier
- Gorgojo-galindo Oscar
- Guaragna Florencia
- Guegel Genilson P.
- Guillén-guío Beatriz
- Guillén-navarro Encarna
- Guisado-vasco Pablo
- Gutiérrez-bautista Juan F.
- Gutiérrez-castañeda Luz D.
- Gómez Carrera Luis
- Gómez García María
- Gómez Sacristán Ángela
- Gómez-arrue Javier
- Gómez-duque Mario
- Górgolas Miguel
- Heili-frades Sara
- Hernández Estefania
- Hernández-moro Cristina
- Hernández-ortega Luis D.
- Hernández-pérez Guillermo
- Hernández-vaquero Rebeca
- Herranz M. Teresa
- Herrera María
- Herrero María José
- Herrero-gonzález Antonio
- Herráez Belén
- Horcajada Juan P.
- Imaz-ayo Natale
- Intxausti-urrutibeaskoa Maider
- Jacomo Rafael H.
- Jara Rubén
- Jiménez Pilar
- Jiménez Ángel
- Jiménez-alfaro Ignacio
- Jiménez-sousa María A.
- Jordan Iolanda
- Laguna-goya Rocío
- Laorden Daniel
- Lapunzina Pablo
- Lasa-lázaro María
- Lattig María Claudia
- Lauriente Ailen
- Liger Borja Anabel
- Llanos Lucía
- Lopez-garcia Esther
- Lopez-rodriguez Rosario
- Lorente Leonardo
- Lorenzo-salazar José M.
- Lozano José E.
- Lozano-espinosa María
- Luchessi Andre D.
- López De Heredia Miguel
- López De Heredia Miguel
- López-bernús Amparo
- López-granados Eduardo
- López-ruz Miguel A.
- Mahillo Ignacio
- Mancebo Esther
- Mar Carmen
- Marcelo Calvo Cristina
- Marcos Miguel
- Marcos-delgado Alba
- Mariscal-aguilar Pablo
- Martin-fernandez Marta
- Martin-pedraza Laura
- Martinez Amalia
- Martinez-paz Pedro
- Martín María Dolores
- Martín María M.
- Martín Vicente
- Martín-lópez Caridad
- Martín-oterino José-Ángel
- Martín-vicente María
- Martínez Juan José
- Martínez Ricardo
- Martínez Silvia
- Martínez-aquino Eleno
- Martínez-gonzález Óscar
- Martínez-lópez Iciar
- Martínez-nieto Óscar
- Martínez-pérez Ángel
- Martínez-ramas Andrea
- Martínez-reséndez Michel F.
- Martínez-robles Violeta
- Marzal Laura
- Marín-candón Alicia
- Maya Belén Rodríguez
- Mazzeu Juliana F.
- Medeiros Jeane F. P.
- Medeiros Kelliane A.
- Medrano Francisco J.
- Meijome Xose M.
- Mejuto-montero Natalia
- Mendes Ingrid
- Mendoza Charris Humberto
- Merayo Macías Eleuterio
- Mercadillo Fátima
- Mercado-sesma Arieh R.
- Molina Antonio J. J.
- Molina-roldán Elena
- Montoya Juan José
- Moraes Vitor M. S.
- Moreira-escriche Patricia
- Morelos-arnedo Xenia
- Moreno Cuerda Víctor
- Moreno Fernández Alberto
- Moreno Rocío
- Moreno-docón Antonio
- Moreno-escalante Junior
- Morilla Rubén
- Muñoz García Patricia
- Méndez-echevarría Ana
- Mínguez Pablo
- Neira Pablo
- Nevado Julián
- Nieto-gañán Israel
- Nunes Joana F. R.
- Nuñez-torres Rocío
- Obrador-hevia Antònia
- Ocejo-vinyals J. Gonzalo
- Olivar Virginia
- Oliveira Silviene F.
- Olivera María Rubio
- Ondo Lorena
- Orfao Alberto
- Ortega Luis
- Ortega-paino Eva
- Ortiz-flores Fernando
- Ortiz-lópez Rocío
- Oteo José A.
- Pacheco Manuel
- Pacheco-miranda Fredy Javier
- Padilla-conejo Irene
- Panadero-fajardo Sonia
- Parellada Mara
- Pariente-rodríguez Roberto
- Paz-artal Estela
- Peces-barba Germán
- Pedromingo Kus Miguel S.
- Perales Celia
- Perucho Teresa
- Pichardo Lisbeth A.
- Pinho Susana M. T.
- Pinsach-abuin Mel·lina
- Pinzón Luz Adriana
- Pita Guillermo
- Pla-juncà Francesc
- Planas-serra Laura
- Pompa-mera Ericka N.
- Porras-hurtado Gloria L.
- Pujol Aurora
- Pérez Alexandra
- Pérez César
- Pérez María Jazmín
- Pérez Patricia
- Pérez-de-nanclares Gustavo
- Pérez-garcía Felipe
- Pérez-jurado Luis A.
- Pérez-matute Patricia
- Pérez-tomás M. Elena
- Quevedo-chávez María Eugenia
- Quijada Maria Angeles
- Quintela Inés
- Quintela Inés
- Ramiro-león Soraya
- Rascado Sedes Pedro
- Recalde Delia
- Recio-fernández Emma
- Resino Salvador
- Riancho José A.
- Ribeiro Adriana P.
- Rivadeneira-chamorro Carlos S.
- Roa-agudelo Diana
- Robelo Pardo Montserrat
- Rodriguez Marilyn Johanna
- Rodriguez-nicolas Antonio
- Rodriguez-palmero Agustí
- Rodriguez-urrego Paula A.
- Rodríguez-artalejo Fernando
- Rodríguez-ferrer Marena
- Rodríguez-gallego Carlos
- Rodríguez-garcía José A.
- Rodríguez-hernández María A.
- Rodríguez-novoa German Ezequiel
- Rodríguez-ruiz Emilio
- Rojas-martinez Augusto
- Rojo Federico
- Romero-coronado Andrea
- Rondón-garcía Filomeno
- Rosa Lidia S.
- Rosales-castillo Antonio
- Rubio Cladelis
- Ruiz Montserrat
- Ruiz-cabello Francisco
- Ruiz-casares Eva
- Ruiz-cubillan Juan J.
- Ruiz-hornillos Javier
- Ryan Pablo
- Salamanca Hector D.
- Salazar-garcía Lorena
- Salgueiro-origlia Giorgina Gabriela
- Sancho-sainz Cristina
- Sande Esther
- Sangil Anna
- Santos Arnoldo
- Santos Ney P. C.
- Schlüter Agatha
- Scourge Cohort Group
- Segovia Sonia
- Serra-llovich Alex
- Sevil-puras Fernando
- Sevilla-porras Marta
- Sicolo Miguel A.
- Silbiger Vivian N.
- Silva Fabiola T. C.
- Silva Gabriela V.
- Silva Nayara S.
- Silván-fuentes Cristina
- Solé-violán Jordi
- Soria José Manuel
- Sorlí Jose V.
- Sousa Renata R.
- Souto Juan Carlos
- Souza Karla S. C.
- Souza Vanessa S.
- Sprockel John J.
- Suárez-rama José Javier
- Suárez-zamora David A.
- Sánchez López Antonio J.
- Sánchez Pedro-luis
- Sánchez-carpintero Abad María
- Sánchez-pablo Clara
- Sánchez-pernaute Olga
- Sánchez-prados María Concepción
- Sánchez-real Javier
- Sánchez-redondo Jorge
- Taboada-fraga Xiana
- Tamayo Eduardo
- Tamayo-velasco Alvaro
- Taracido-fernández Juan Carlos
- Tavares Nathali A. C.
- Tellería Carlos
- Tenorio-castaño Jair Antonio
- Teper Alejandro
- Torres-gutiérrez Ronald P.
- Torres-macho Juan
- Torres-tobar Lilian
- Troya Jesús
- Urioste Miguel
- Valencia-ramos Juan
- Valido Agustín
- Vargas-gallo Juan Pablo
- Varón Belén
- Vasconcelos Romero H. T.
- Vega Tomas
- Velasco-quirce Santiago
- Vidán-estévez Julia
- Vieitez-santiago Miriam
- Vilches Carlos
- Villalobos Lavinia
- Villar Felipe
- Villar-garcia Judit
- Villaverde Cristina
- Villoslada-blanco Pablo
- Virseda-berdices Ana
- Vélez-santamaría Valentina
- Víctor Virginia
- Yáñez Zuleima
- Zapatero-gaviria Antonio
- Zarate Ruth
- Zazo Sandra
- Álvarez Nuria
- Álvarez-benítez Yady
- Álvarez-navia Felipe
- Álvarez-sala Walther Rodolfo
- Íñigo-campos Antonio
- Íñiguez María
- Publication venue
- Springer Science and Business Media LLC
- Publication date
- 08/05/2024
- Field of study
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality
RICORS2040 : The need for collaborative research in chronic kidney disease
- Author
- Agilar M.A.
- Agudo C.P.B.
- Aguiar P.V.A.
- Albadalejo López Santiago
- Alonso J.
- Alvarez-Llamas G.
- Amador M.M.
- Andujar A.M.
- Arduan A.O.
- Arellano Armisen Manuel
- Arenas M.D.
- Arias B.P.
- Arias L.M.
- Ars Elisabet
- Bajo M.J.R.
- Balboa N.E.
- Baltanas R.L.
- Bardaji A.M.
- Barja L.M.C.
- Barreiro A.S.
- Barreiro J.M.L.
- Barrera C.B.
- Barrio M.C.
- Bartolomé M.F.
- Basilio L.C.
- Becerra B.R.
- Belmonte A.A.
- Benito-Hernández A.
- Benítez P.R.
- Berenguer Marina
- Bermejo M.L.G.
- Bermúdez A.I.R.
- Betsabé I.T.
- Blanch N.L.
- Blasco Pelicano Miquel
- Boillos A.B.
- Bonet L.A.
- Bonilla J.L.A.
- Boque E.C.
- Bordignondraibe J.
- Borra J.M.
- Bravo M.Á.G.
- Caballero A.
- Cabello M.
- Cabrales C.A.
- Cabrera B.E.
- Cabrera C.V.
- Cabrera M.L.
- Cachaza N.C.
- Calabia E.R.
- Calvo I.F.
- Canal Girol Cristina
- Cannata Andía J.B.
- Carrasco A.G.
- Carro B.M.
- Casanova Paso A.G.
- Caso C.
- Caso M.D.L.Á.C.
- Castañeda J.R.M.
- Castelao A.M.
- Castiñeira J.R.V.
- Catalina M.C.
- Cenarruzabeitia N.V.
- Centenera G.O.
- Chamond M.R.R.
- Cobo Caso M.D.L.A.
- Correa P.S.
- Corte M.D.C.D.
- Cuarental L.
- Cucchiari David
- Córdoba-David G.
- de Arriba Gabriel
- De Gracia Guindo M.D.C.
- De La Iglesia A.M.B.
- De Lamo V.M.
- De Los Angeles M.
- De Mier M.V.P.R.
- De Miguel P.M.
- De Montaner E.R.A.
- De Ona J.G.
- de Sequera Patricia
- Delgado J.B.
- Delgado N.P.
- Diekmann F.
- Diezhandin M.G.
- Donate-Correa J.
- Díaz Encarnación Montserrat Mercedes
- Díaz M.N.
- Díaz M.N.
- Eijo A.C.
- Enriquez M.C.
- Escribano T.C.
- Expósito L.M.
- Facundo Carme
- Fajardo J.P.T.
- Favero C.
- Fernandez Fresnedo Gema
- Fernández Rodríguez M.A.
- Fernández A.L.
- Fernández A.S.
- Fernández M.P.
- Fernández N.G.
- Fernández-Fernández B.
- Fondevila Campo Constantino
- Font M.X.
- Fontan F.C.
- Fontan M.P.
- Fontecha-Barriuso M.
- Fuentes M.D.C.R.
- Fuentes R.W.
- Furlano Monica
- G. Cosio M. Dolores
- Gallardo M.L.
- Gallego Zurro Daniel
- Gallego R.H.
- Galán A.D.
- Gamboa M.J.R.
- Gamboa M.R.
- Garcia Rebollo M.S.
- García E.C.
- García E.R.
- García L.Á.
- García M.E.G.
- García M.R.
- García P.G.
- García S.P.
- García-Jiménez J.
- García-Menéndez E.
- Garrido R.G.D.M.
- Garrido R.S.J.
- Garriel M.P.
- Garrit J.M.C.
- Genis B.B.
- Gigarrán-Guldris S.
- Gilsanz G.D.P.
- Goicoechea Marian
- González A.O.
- González A.Á.
- González L.R.
- González M.G.
- González M.O.
- González M.V.
- González M.Á.G.N.
- González O.C.
- González V.P.
- González Á.G.
- Gorostidi Pérez Manuel
- Guerrero-Mauvecin J.
- Guillen M.A.
- Guirado Luis
- Gutiérrez Porras Inmaculada
- Gutiérrez R.L.
- Gómez Gómez Clemente
- Gómez Ruiz Josefa
- Gómez A.P.
- Gómez J.M.L.
- Gómez M.B.
- Haad C.R.
- Heffernan J.A.J.
- Hernandez Marrero Domingo
- Hernández A.F.
- Hernández A.P.R.
- Hernández M.R.
- Hernández R.M.
- Hernández S.B.
- Hernández Á.A.
- Herranz V.M.
- Huerta E.L.
- Huertas S.S.
- Iglesias V.C.
- Jacobs-Cachá C.
- José R.M.S.
- Jover A.S.
- Juárez G.M.F.
- Juárez J.R.
- Lahuerta J.I.H.
- Larrea C.L.
- Lavilla F.J.
- Lechuga J.A.
- León M.
- Llavona E.C.
- Lopez-Díaz A.M.
- Lourdes M.
- Lucas M.F.
- Luengas I.L.M.
- Luis-Lima S.
- López Hernández F.J.
- López J.J.V.
- López M.B.
- López N.C.
- López V.
- López-Hoyos M.
- Majoral J.S.
- Mallen P.D.
- Mallol L.L.
- Malo A.M.
- Maneus E.B.
- Marchant V.
- Marcos E.M.
- Marimont M.B.
- Mariño F.J.J.
- Marqués M.
- Marrah E.M.
- Martin Orgaz Jose Manuel
- Martin P.
- Martos C.M.P.
- Martín C.J.
- Martín C.M.
- Martín J.L.F.
- Martín-Nuñez E.
- Martínez Jiménez Victor
- Martínez A.M.S.
- Martínez C. M.
- Martínez E.G.
- Martínez J.M.C.
- Martínez M.L.
- Martínez S.M.S.
- Masot N.D.
- Matamoros O.B.
- Mateo G.T.G.
- Mateos F.J.M.
- Mateos F.M.
- Mateos S.R.
- Mazuecos Auxiliadora
- Melilli E.
- Meneghini M.A.E.
- Millán J.C.R.S.
- Miranda D.M.
- Miñambres Eduardo
- Miñano J.A.P.
- Molina M.C.
- Molina Á.G.
- Montero A.M.
- Montes C.A.
- Mora-Fernández M.D.C.
- Morales Martín A.I.
- Moreno Barón Marta
- Moreno E.C.
- Moreno I.D.D.
- Moreno J.M.M.
- Murias M.G.
- Muñoz A.C.
- Muñoz L.S.
- Muñoz M.E.R.
- Muñoz M.O.V.
- Muñoz-Bellvis Luis
- Nadah H.B.
- Navarro-González J.
- Oliva M.L.
- Oliva M.R.
- Oliveras X.F.
- Olmo R.S.
- Ongil S.L.
- Ortega A.O.
- Ortega M.R.
- Ortiz Alberto
- Ortiz M.E.R.
- Ortiz P.J.C.
- Ortiz P.S.
- Pachón M.D.R.
- Palacios A.M.C.
- Panadés E.S.
- Parra E.G.
- Pavón F.G.
- Pelaez S.L.
- Pelicano J.M.B.
- Peregrin C.M.
- Perez Contreras Javier
- Perez Tamajon M.L.
- Peña H.G.
- Pintor-Chocano A.
- Piñeiro G.J.
- Piñeiro P.B.
- Plana J.M.C.
- Porras A.B.
- Porras L.F.Q.
- Porrini E.
- Portoles J.
- Prado R.F.
- Puyol D.R.
- Pybus Marc
- Pérez Bermúdez Pilar
- Pérez M.P.
- Pérez N.M.
- Pérez-Aradros J.C.
- Pérez-Gómez M.V.
- Pérez-Monteoliva N.R.R.
- Quiroga Borja
- Ramos A.M.
- Ramos S.A.
- Ravassa F.O.V.
- Rebollo G.
- Rebollo M.S.G.
- Redondo E.D.B.
- Revilla J.M.V.
- Ribagorda M.
- Ribera A.T.
- Rinne A.M.G.
- Rituerto D.C.
- Rivera J.R.
- Rodiguez N.Z.
- Rodrigues-Diez R.R.
- Rodriguez Perez Jose Carlos
- Rodriguez Mariano
- Rodríguez C.D.
- Rodríguez F.S.
- Rodríguez G.G.
- Rodríguez L.F.
- Rodríguez M.L.
- Rodríguez N.Z.
- Rodríguez R.M.
- Rodríguez S.G.
- Roger Marta
- Roig J.S.
- Romeo Casabona Carlos Maria
- Rosell M.N.S.
- Rubio E.
- Rubio M.A.B.
- Ruiz P.
- Saborido M.I.T.
- Sagrario M.
- Salgado C.M.
- Salido J.A.
- Salinas F.O.
- Sanjuan A.E.
- Sans Atxer Laia
- Santos J.P.
- Sanz A.B.
- Saénz D.S.
- Seara M.A.F.
- Segundo D.S.
- Serra C.R.
- Serra Núria
- Serrano B.M.
- Serrano E.M.A.R.
- Serres F.E.B.
- Silva Irene
- Sola E.
- Sole L.C.
- Soler Romeo Maria Jose
- Soriano Cabrera Mª Sagrario
- Sosa D.Á.
- Stanojevic M.B.
- Sáez M.J.P.
- Sánchez Álvarez José Emilio
- Sánchez F.P.
- Sánchez S.P.
- Sánchez-Niño M.D.
- Sánchez-Rodríguez J.
- Sánchez-Sobrino B.
- Tamajon P.
- Tamajón M.L.P.
- Tejedor-Santamaria L.
- Tejera-Muñoz A.
- Tejero E.A.
- Terente M.P.
- Terroba Y.A.
- Teruel J.L.G.
- Tocados J.M.D.
- Toro L.C.
- Torra Balcells Roser
- Torres A.
- Torres Armando
- Torres C.C.
- Torres M.P.R.
- Torres S.E.
- Tortosa C.L.R.
- Val M.H.
- Valdemoros R.L.
- Valero R.
- Valiño-Rivas L.
- Varela J.C.
- Velázquez Á.S.
- Verde A.M.R.
- Vicente I.R.
- Vicente L.V.
- Vicente M. P.
- Vila L.E.
- Villalba I.L.
- Villanueva R.S.
- Villares J.M.P.
- Virgala J.M.
- Vázquez A.L.
- Zamorano S.M.
- Zelaya F.M.
- Álvarez B.S.
- Álvarez C.G.
- Álvarez E.S.
- Álvarez M.L.S.
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Chronic kidney disease (CKD) is a silent and poorly known killer. The current concept of CKD is relatively young and uptake by the public, physicians and health authorities is not widespread. Physicians still confuse CKD with chronic kidney insufficiency or failure. For the wider public and health authorities, CKD evokes kidney replacement therapy (KRT). In Spain, the prevalence of KRT is 0.13%. Thus health authorities may consider CKD a non-issue: very few persons eventually need KRT and, for those in whom kidneys fail, the problem is 'solved' by dialysis or kidney transplantation. However, KRT is the tip of the iceberg in the burden of CKD. The main burden of CKD is accelerated ageing and premature death. The cut-off points for kidney function and kidney damage indexes that define CKD also mark an increased risk for all-cause premature death. CKD is the most prevalent risk factor for lethal coronavirus disease 2019 (COVID-19) and the factor that most increases the risk of death in COVID-19, after old age. Men and women undergoing KRT still have an annual mortality that is 10- to 100-fold higher than similar-age peers, and life expectancy is shortened by ~40 years for young persons on dialysis and by 15 years for young persons with a functioning kidney graft. CKD is expected to become the fifth greatest global cause of death by 2040 and the second greatest cause of death in Spain before the end of the century, a time when one in four Spaniards will have CKD. However, by 2022, CKD will become the only top-15 global predicted cause of death that is not supported by a dedicated well-funded Centres for Biomedical Research (CIBER) network structure in Spain. Realizing the underestimation of the CKD burden of disease by health authorities, the Decade of the Kidney initiative for 2020-2030 was launched by the American Association of Kidney Patients and the European Kidney Health Alliance. Leading Spanish kidney researchers grouped in the kidney collaborative research network Red de Investigación Renal have now applied for the Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS) call for collaborative research in Spain with the support of the Spanish Society of Nephrology, Federación Nacional de Asociaciones para la Lucha Contra las Enfermedades del Riñón and ONT: RICORS2040 aims to prevent the dire predictions for the global 2040 burden of CKD from becoming true
CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3
- Author
- Adelina Gimeno
- Alba Belles
- Alba Rivera
- Almudena Tinajas
- Amparo Coira Nieto
- Ana Isabel López-Calleja
- Andrés Canut Blasco
- Antonio Casabella Pernas
- Antonio Oliver
- Antonio Oliver
- Belén Aracil
- Belén Aracil
- Caridad Sainz de Baranda
- Carmen Aldea
- Carmen Aspiroz
- Carmen Liébana
- Carmina Martí Sala
- Carolina Roldán
- Cristina Pitart
- Cristina Seral
- Cristobal del Rosario and Jose Luis Perez Arellano
- Desirèe Gijón
- Desirèe Gijón
- Emilia Cercenado
- Encarnación Clavijo
- Ester Clapés Sanchez
- Eugenio Garduño
- Eva Riquelme Bravo
- Fe Tubau Quintano
- Federico García
- Fernando García Garrote
- Ferran Navarro
- Francisco Javier Ramos
- Fátima Galán Sánchez
- Genoveva Yagüe Guirao
- Germán Bou
- Germán Bou
- Guillermo Ruiz-Carrascoso
- Inmaculada García García
- Irene Gracia-Ahufinger
- Irene Gracia-Ahufinger
- Javier Castillo
- Javier E. Cañada-García
- Javier E. Cañada-García
- Jennifer Villa
- Jesús Oteo-Iglesias
- Jesús Oteo-Iglesias
- Jesús Rodríguez-Baño
- Jordi Vila
- Jordi Vila
- Jorge Calvo
- Jorge Calvo
- Jorge Gaitán
- Jose Luis Barrios Andrés
- Jose Luis Díaz de Tuesta
- José Gutierrez Fernández
- José Leiva and José Luis del Pozo
- José Manuel Azcona
- José María Saavedra
- Juan José González-López
- Juan José González-López
- Juan Manuel Sánchez Hospital de Jérez
- Laura Mora
- Leyre López Soria
- Lidia Garcia Agudo and Soledad Illescas
- Lucía Martínez Lamas
- Luis López-Urrutia Lorente
- Luis Martínez-Martínez
- Luis Martínez-Martínez
- Luis Martínez-Martínez
- Luis Torres Sopena
- M. Pilar Ortega Lafont
- M.a José Rodríguez Escudero
- Ma Dolores Quesada
- Ma Isabel Cabeza
- Ma Isabel Fernández Natal and Marta Arias
- Ma Isabel Paz Vidal
- Ma Luisa Pérez del Molino Bernal
- Ma Luz Albina Cordón Rodriguez
- Ma Teresa Cabezas Fernández
- Mar Olga Pérez Moreno
- Maria Pilar Chocarro
- Mariela Martínez Ramírez
- Marta Lamata Subero
- María E. Cano
- María Gomáriz Díaz
- María Huertas
- María Lecuona
- María Pérez-Vázquez
- María Pérez-Vázquez
- Matxalen Vidal-García
- Mercedes Delgado-Valverde
- Mercedes Delgado-Valverde
- Mercè García González
- Miriam Albert Hernández
- Miriam Valverde Troya and Begoña Palop
- Moises García Bravo
- Mónica González
- Mónica González
- Natalia Chueca
- Nerea Sanchez
- Nieves Gonzalo Jiménez
- Nieves Larrosa
- Nieves Larrosa
- Nuria Iglesias Nuñez
- Nuria Prim
- Oscar Esparcia Rodríguez
- Pedro de la Iglesia
- Pedro J. Sola-Campoy
- Pilar Zamarrón
- Rafael Cantón
- Rafael Cantón
- Rafael Sánchez Arroyo
- Raquel Elisa Rodríguez Tarazona
- Rosario Sánchez Benito
- Salvador Giner and Juan Frasquet
- Sonia Rey Cao
- Susana Hernando
- Susana Sabater
- the GEMARA/GEIRAS-SEIMC/REIPI CARB-ES-19 Study Group
- Xavier Mulet
- Xavier Mulet
- Zaira Moure
- Zaira R. Palacios-Baena
- Zaira R. Palacios-Baena
- Zaira R. Palacios-Baena
- Álvaro Pascual
- Álvaro Pascual
- Álvaro Pascual
- Publication venue
- Frontiers Media S.A.
- Publication date
- 01/06/2022
- Field of study
ObjectivesCARB-ES-19 is a comprehensive, multicenter, nationwide study integrating whole-genome sequencing (WGS) in the surveillance of carbapenemase-producing K. pneumoniae (CP-Kpn) and E. coli (CP-Eco) to determine their incidence, geographical distribution, phylogeny, and resistance mechanisms in Spain.MethodsIn total, 71 hospitals, representing all 50 Spanish provinces, collected the first 10 isolates per hospital (February to May 2019); CPE isolates were first identified according to EUCAST (meropenem MIC > 0.12 mg/L with immunochromatography, colorimetric tests, carbapenem inactivation, or carbapenem hydrolysis with MALDI-TOF). Prevalence and incidence were calculated according to population denominators. Antibiotic susceptibility testing was performed using the microdilution method (EUCAST). All 403 isolates collected were sequenced for high-resolution single-nucleotide polymorphism (SNP) typing, core genome multilocus sequence typing (cgMLST), and resistome analysis.ResultsIn total, 377 (93.5%) CP-Kpn and 26 (6.5%) CP-Eco isolates were collected from 62 (87.3%) hospitals in 46 (92%) provinces. CP-Kpn was more prevalent in the blood (5.8%, 50/853) than in the urine (1.4%, 201/14,464). The cumulative incidence for both CP-Kpn and CP-Eco was 0.05 per 100 admitted patients. The main carbapenemase genes identified in CP-Kpn were blaOXA–48 (263/377), blaKPC–3 (62/377), blaVIM–1 (28/377), and blaNDM–1 (12/377). All isolates were susceptible to at least two antibiotics. Interregional dissemination of eight high-risk CP-Kpn clones was detected, mainly ST307/OXA-48 (16.4%), ST11/OXA-48 (16.4%), and ST512-ST258/KPC (13.8%). ST512/KPC and ST15/OXA-48 were the most frequent bacteremia-causative clones. The average number of acquired resistance genes was higher in CP-Kpn (7.9) than in CP-Eco (5.5).ConclusionThis study serves as a first step toward WGS integration in the surveillance of carbapenemase-producing Enterobacterales in Spain. We detected important epidemiological changes, including increased CP-Kpn and CP-Eco prevalence and incidence compared to previous studies, wide interregional dissemination, and increased dissemination of high-risk clones, such as ST307/OXA-48 and ST512/KPC-3
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- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
- Bakas Apostolos
- Baker Helen
- Baker Nerilee
- Balasubramanian Madhu
- Balbay Abidin Oner
- Balon Sandrine
- Bantar Ana
- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
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- Baumber Rachel
- Baxter Karen
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- Bean Sarah
- Becker Cathy
- Becker Delmiro
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- Beker Tatjana
- Bekos Vasileios
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- Belkhair Wesal Ali
- Belskiy Vladislav
- Ben-Hamouda Nawfel
- Ben-Jacob Talia
- Benbenishty Julie
- Bench Suzanne
- Bendelari Valentina
- Benlamin Mohamed
- Berry Gillian
- Bertoletti Fernando Pablo
- Besbes Lamia
- Besbes Lamia Ouanes
- Besch Guillaume
- Bestle Morten
- Beuret Pascal
- Bhakhtiani Lakshay
- Bhargava Vaibhav
- Bi AiPing
- Bianchini Suzana
- Bielskute Egidija
- Bilawicz Jan
- Binda Filipo
- Birgisdottir Hrönn
- Birgisdóttir Hrönn
- Bispo Bruno Miguel
- Biston Patrick
- Bjorgen Hege
- Blackwood Bronagh
- Blanc Agnès
- Blanco Daniel
- Blanco Maria Pilar Sogues
- Blasco Maria Luisa
- Bliksted Inger Abildgaard
- Blondal Asbjorn
- Bloos Frank
- Blot Stijn I.
- Bo Qi
- Bocui Nie
- Boedjawan Naraindath N.
- Bogarin Javier
- Bogoevska-Miteva Zaneta
- Bonaccorso Luciano
- Bongiorno Benjamin
- Bonsignore Pablo Julio Maldonaldo
- Borgognoni Cinzia
- Borin Christophe
- Borkowska Marta
- Bormans Laura
- Boroli Filippo
- Borys Michal
- Boschetto Margherita
- Bossolasco Matteo
- Bota Marc
- Boulanger Carole
- Boulton Karen
- Bowes Bonnie
- Boyer Laetitia
- Bozbay Suha
- Bozena Armanda
- Bratsberg Bjorn
- Bravo Silvina
- Brett Carole
- Brett Stephen
- Brett Stephen J.
- Briva Arturo
- Brizio Elisabetta
- Brizuela Patricia
- Broadhurst Phil
- Brown Wendy
- Browne Troy
- Bruel Cédric
- Bruhn Louise
- Brumwell Sarah
- Bruni Andrea
- Bruno Anna Vita
- Buckley Sarah
- Bull Rhian
- Bumbasirevic Vesna
- Buregeya Egide
- Burns Karen
- Butcher Rand
- Byers Heather
- Bösl Kathrin
- Cabral Dolly Mabel Bordon
- Cabral João
- Cabrita Paula
- Caddell Paul
- Caicedo Nestor
- Calamai Italo
- Calili Duygu Kayar
- Caliskan Gulbahar
- Calleja Pablo Lopez-Arcas
- Calpe Neus
- Calvino-Gunther Silvia
- Campanili Ticiane
- Campbell Elizabeth
- Campos Pierina Arias
- Campos-Perez Margarita
- Camputaro Luis
- Camsooksai Julie
- Canales Julieta
- Canete Fidelina
- Cani Alma
- Cano Anastasio Espejo
- Cao Deyan
- Cao Wenzhen
- Cao Ying
- Cao Zu Qing
- Capuzzi Fabio
- Cardenas Yenny
- Carey Annette
- Carney Dominic
- Carter Charlotte
- Casaioli Simona
- Castelain Vincent
- Castiglione Giacomo
- Cata Juan
- Cavaco Raquel
- Cengiz Melike
- Cerezo Franklin Dean
- Cesar Helena
- Cespedes Laura
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- Chadwick Llesley
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- Chang Youjin
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- Chao Yu
- Chaparro Javiera
- Chaparro Silvia
- Chapeta Edwin
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- Chen Feifei
- Chen Haiyan
- Chen Hongjuan
- Chen Jingfang
- Chen Lei
- Chen Meili
- Chen Tianfei
- Chen Wenmin
- Chen Xiaoyan
- Chen Zhihong
- Cheng
- Cheng Jiyin
- Chime Christiana
- Chimunda Tim
- Chinardet Benoît
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- Christ Martin
- Christofis Christos
- Chueca Ramon Molina
- Chunhua Gao
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- Clesi Tara
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- Collet Marie
- Collins Amy
- Coman Mary
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- Constantinou Constantina
- Corcoran Ailesh
- Coremans Stefano
- Correia Malcolm C.
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- Cosano Rosario
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- Craig Jayne
- Cranmer Karen
- Cranshaw Julius
- Creber Peter
- Crone Petra
- Cui Xia
- Cummings Donna
- Cupitt Jason
- Curilen Veronica
- Czuczwar Miroslaw
- Dagooc Rica
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- Das Sasidharan Nair Vishnu
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- Davidson Cheryl
- Dawn Frances
- Dayan Meneses
- de Almeida Angelica Olivetto
- de Anda Gilberto Felipe Vazquez
- De Bels David
- de Ceballos José Peral Gutierrez
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- De lange Dylan
- De Lange Dylan
- de Molina Serrano José Ivan Rodriguez
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- De Pablo Ana María
- De Rosa Silvia
- De Sanctis Francesca
- De Schryver Nicolas
- De Wit Irene
- Dean Emiliano
- Debue Anne-Sophie
- Del Bosque Diez Rosa
- del Cotillo Mercedes
- del Mar Diaz Salcedo Maria
- Del Moral Armengol Mario
- Del Rio Cabajo Lorena
- del Rosario Villar Redondo M.
- del Valle Gimenez Graciela
- Delgado Carlos Castro
- Delgado Patricia
- Dellafiore Federica
- Delossantos Shella
- Delve Peter
- Demarré Liesbet
- Demirkiran Oktay
- Dendane Tarek
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- von Lewinski Dirk
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- Vymazal Tamas
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- Wahab Sherliza
- Wahlbom Ewa
- Waibel Hansjoerg
- Wallin Ewa
- Walsh Amy
- Wan Jianhong
- Wan Yan
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- Wang Ying
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- Watts Stacey
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- Wei Dongfang
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- Wei Ying
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- White Joanne
- White Nigel
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- Xiao Lina
- Xiao Min
- Xiao Yan
- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
- Yang Qiao
- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
- Ye Man
- Ye Mei
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- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
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- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- 'Organisation for Economic Co-Operation and Development (OECD)'
- Publication date
- 26/02/2021
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Recommended from our members
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
- Bakas Apostolos
- Baker Helen
- Baker Nerilee
- Balasubramanian Madhu
- Balbay Abidin Oner
- Balon Sandrine
- Bantar Ana
- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
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- Belskiy Vladislav
- Ben-Hamouda Nawfel
- Ben-Jacob Talia
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- Berry Gillian
- Bertoletti Fernando Pablo
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- Bestle Morten
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- Bhakhtiani Lakshay
- Bhargava Vaibhav
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- Birgisdóttir Hrönn
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- Cabral Dolly Mabel Bordon
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- de Almeida Angelica Olivetto
- de Anda Gilberto Felipe Vazquez
- De Bels David
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- De Haan Marina
- de Jesús Ortiz Alberto
- de la Ventana Ana Belén Sánchez
- De lange Dylan
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- Dormans Tom
- Douschan Philipp
- Doyle Deirdre
- Dragoumanis Christos
- Du Guifang
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- D’Ambrosio Francesco
- D’Ambrosio Paolo
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- Efthymiou Anna
- Egi Moritoki
- Egorova Natalya
- Ei Poe Poe
- Elatrous Souheil
- Elay Gülseren
- Elgammudi Mala
- Elhadi Ahmed
- Elhadi Muhammed
- Elhechmi Youssef Zied
- Elkhayari Mina
- Ellazar Chris Gerome
- Eller Philipp
- Eltorai Ashley Szabo
- Enamorado Judy
- Enamorado Judy Enamorado
- Eneas Antony
- Eng Timothy
- Erdivanli Başar
- Erdogan Elif
- Eroglu Ahmet
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- Escalante Rosana Gabriela
- Espinosa Cristina Paños
- Esposito Romina
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- Etourneau Fabienne
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- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
- Ye Man
- Ye Mei
- Yeni Nomhle Princess
- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
- Young Charlotte
- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- Intensive Care Medicine
- Publication date
- 09/04/2021
- Field of study
The original version of this article unfortunately contained a mistake
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Aaron Joffe
- Aaron Mark Hernandez
- Aaron Mark Hernandez
- Abby Lewis
- Abdelhamid Hachimi
- Abdualhamid I Alshrif
- Abel Viveiros
- Abhijit Duggal
- Abidin Oner Balbay
- Achilleas Chovas
- Ade Susanti
- Adi Hadzibegovic
- Adonis Dungca
- Adrian Belii
- Adrian Belii
- Adriana Onelli
- Afolabi Owojuyigbe
- Agnieszka Kubisz-Pudelko
- Agnès Blanc
- Ahmed Ali Aboufray
- Ahmed Elhadi
- Ahmed Ramadan Triki
- Ahmed Subhy Alsheikhly
- Ahmed Zaki
- Ahmet Eroglu
- Aidan O'Shea
- Aikaterini Dimoula
- Aikaterini Efthimiou
- Aikaterini Flevari
- Ailesh Corcoran
- AiPing Bi
- Aiua Ren
- Aizhi Zhang
- Ajitha Rajendran
- Akemi Hirao
- Akira Ohuchi
- Aktham Yaghi
- Ala Khaled
- Alan Sustic
- Alan Sustic
- Alba Riera
- Alban Greca
- Alberto de Jesús Ortiz
- Alberto Peratoner
- Alejandra Aucapina
- Alejandra Azahara Marguello Fernandez
- Alejandro Ibarra
- Aleksandar Šuput
- Aleksandra Gutysz-Wojnicka
- Alessandra Negro
- Alessandro Di Risio
- Alessandro Galazzi
- Alexander Dullenkopf
- Alexander Kiselev
- Alexander Tsarev
- Alexandra Pivkina
- Alexandra Vasquez
- Alexis Tabah
- Ali Kağnıcı
- Alida Moise
- Aline Ramalho
- Alinoy Lavy
- Alisha van Axel
- Alma Cani
- Alvaro Ortega Guerrero
- Amalia Corso
- Amber Markham
- Amelia Ferreira
- Amer Assiri
- Amilcar Garcia
- Amilcar Garcia
- Amit Gupta
- Amit Gupta
- Amy Collins
- Amy Thompson
- Amy Walsh
- Amylkar Garay Reyes
- Amylkar José Garay Reyes
- Ana Alabart Llinas
- Ana Alícia Velarde Pineda
- Ana Bantar
- Ana Belén Curto Polo
- Ana Belén Sánchez de la Ventana
- Ana Diaz
- Ana Diaz
- Ana Isabel Clement
- Ana Laura Gonzalez
- Ana Lucia Vitti Ronchini
- Ana Margarida Feranandes
- Ana María De Pablo
- Ana Pascual-Bielsa
- Ana Tavares
- Ana Vochin
- Ana Wensell Fernández
- Anastasia Spyropoulou
- Anastasio Espejo Cano
- Andeas Stübner
- Andrea Bruni
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Giampaoletti
- Andrea Martonova
- Andrea Martonova
- Andrea McDonnell
- Andrea McLucas
- Andrej Markota
- Andrijan Kartalov
- Andréa Maria Laizner
- Andréa Maria Laizner
- Andréa Maria Laizner
- Ane Stenset
- Angela Trposak
- Angelica Olivetto de Almeida
- Anisette Hoegenhaven
- Anita Alias
- Anita Jans
- Anita Vuković
- Anita-Chrysolyte Kusi-Appiah
- Anja Diers
- Anja Hansen
- Ann-Sofie Malvemyr
- Anna Alexandrou
- Anna Diaz
- Anna Efthymiou
- Anna Kyriakoudi
- Anna Leonova
- Anna Vita Bruno
- Anne Fishman
- Anne Langvad
- Anne Marie Kodal
- Anne Sofie Bomholt Pedersen
- Anne Williams
- Anne-Sophie Debue
- Annette Carey
- Annette Toellefsen
- Anthony Adenekan
- Anthony Radavidson
- Antigoni Karathanou
- Anton Turčan
- Antonella Cotoia
- Antonella Mo
- Antoni Margarit Ribas
- Antonia Liarmakopoulou
- Antonija Petosic
- Antonino Rizzo
- Antonio Abdala
- Antonio Barone
- Antonio Landaverde
- Antonio Manzo
- Antonio Margarit Ribas
- Antony Eneas
- Apostolos Bakas
- Arena Raimondo
- Arif Moghal
- Aristeidis Vakalos
- Arlette Van Den Elst
- Armanda Bozena
- Armando Schmukler
- Armorel Salberg
- Artemis Patsalos
- Arturo Briva
- Arvind Baronia
- Asbjorn Blondal
- Ascanio Tridente
- Ashish K Khanna
- Ashish K Khanna
- Ashish Khanna
- Ashley Szabo Eltorai
- Ashok Sundai Raj
- Ashwaq Ali
- Asmah Zainudin
- Asu Ozgultekin
- Ata Mahmoodpoor
- Athena Lavrentieva
- Attilio Quaini
- Audrey Fioretti
- Audrey Massard
- Auke Reidinga
- Auli Palmu
- Avşar Zerman
- Aya Alabuzidi
- Ayako Noguchi
- Ayça Gümüş
- Azmin Huda Abdul Rahim
- Babangida John Sankey
- Badiola Hilario
- Banu Taşdemir
- Baoke Zhang
- Barbara Garcia
- Barbro Meland
- Bart Ramaker
- Basri Mat Nor
- Battsetseg Baasanjav
- Başar Erdivanli
- Başar Erdivanli
- Beatrice Pastore
- Begoña Zalba-Etayo
- Belen Burgos Conde
- Belinda Guadi-Gosh
- Ben Attwood
- Benjamin Bongiorno
- Benjamin Gerretsen
- Benoît Chinardet
- Berenice Navarro
- Bernardo Panka
- Bernardo Panka
- Bernd Oliver Rose
- Bert Loef
- Betty Star Kampayana
- Beverley Thomas
- Beysim Özcan
- Beysim Özcan
- Bhagyesh Shah
- Biljana Kuzmanovska
- Bindu Thankamma
- Bing Song
- Binny Tuinstra
- Birgitte Fosser Johansen
- Birthe Husted
- Biyan Li
- Bjoern Monsen
- Bjorn Bratsberg
- Bodin Khwannimit
- Bogdan Raitsiou
- Bojan Jovanovic
- Bonnie Bowes
- Boğaç Özserezli
- Bram Kilapong
- Bram Kilapong
- Branislava Stefanovic
- Brian Marsh
- Brigitte Tejeda-Huezo
- Brita Fosser Olsen
- Britt Galaaen
- Britt Sjobo
- Britta Jepsen
- Bronagh Blackwood
- Bruno Miguel Bispo
- Bruno Sousa
- Bruno Sousa
- Brynja Rygvadottir
- Burhan Hadri
- Burhan Hadri
- Byung Ju Kang
- Caihong Hui
- Caiju Song
- Caitriona Cody
- Can Turan
- Carita Löfqvist
- Carlo Alberto Volta
- Carlos Alejandro Bascary
- Carlos Castro Delgado
- Carmel Chapman
- Carmel Georgiev
- Carmen Partera Luque
- Carmen Velasco Guillén
- Carole Boulanger
- Carole Boulanger
- Carole Brett
- Carolina Garzón-Tovar
- Carolina Palaez
- Caroline Lagerhäll
- Caroline O'Donnell
- Caroline Paillet
- Carrie Sona
- Casiano Barrera Groba
- Catalin Traian Guran
- Catarina Nunes
- Catarina Tingsvik
- Catherine Motherway
- Catherine O'Brien
- Catherine Smith
- Cathy Becker
- Catia Quagliotto
- Cecilia Inés Loudet
- Cecilia Loudet
- Celia Tirado
- Ceri Lynch
- Cesar Aponte
- Cesar Rodriguez Nuñez
- Chaiwut Sawawiboon
- Chaoqun Ma
- Charalampos Martinos
- Charalice Ramiro
- Charikleia Nikolaou
- Charlotte Carter
- Charlotte Young
- Charlotte Young
- Chen Yumei
- Cheng
- Chenghau Mu
- Chengxia Sun
- Cheryl Bealer
- Cheryl Davidson
- Chiara Gatti
- Chiara Megna
- Chiara Megna
- Cho Young-Jae
- Chris Gerome Ellazar
- Chris Smith
- Chrisi Diakaki
- Christian Ferretti
- Christian Frey
- Christian Theisen
- Christiana Chime
- Christine Fiedler
- Christine Sheehan
- Christophe Borin
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- Christopher Barnes
- Christopher Barnes
- Christopher Palfreeman
- Christopher Potestio
- Christos Christofis
- Christos Dragoumanis
- Chrysanthos Markoulias
- Chrysostomos Katsenos
- Chun Jie Xia
- Chunxia Li
- Cindy Barefield
- Cindy Pillard
- Cintia Valencia Hurtado
- Cinzia Borgognoni
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- Claire Randell
- Claire Reynolds
- Clara Hurtado
- Clara Santa Rita
- Clare Fielding
- Clare Howcroft
- Claude Sertznig
- Claudia Lizbeth Lopez Nava
- Claudia Martins
- Congcong Liu
- Constantina Constantinou
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- Cristian Quiroga
- Cristiana Mota Pinheiro
- Cristina Paños Espinosa
- Cristina Petrisor
- Cui Yuan
- Cynthia Xing
- Cyril Thix
- Cyril Thix
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- Cédric Daubin
- Dagmar Holmquist
- Daira Gonzalez
- Daisy Mehay
- Dale Ventour
- Damei Wang
- Damien O'Connell Rosemary Finn
- Dana Tomescu
- Dana Tomescu
- Danca Lančaričová
- Daniel Blanco
- Daniel Horner
- Daniel Owens
- Daniel Sancho Muriel
- Daniela Alampi
- Daniela Carmen Filipescu
- Danielle Hacking
- Danil Baskakov
- Daria Rabarova
- Dassy Levy
- David De Bels
- David Higgins
- David Perez-Torres
- David Shaw
- Davide Massimo Ghioldi
- Dea Mahanes
- Debbie Noblezada-Uy
- Deborah Jibrin
- DeHong Lei
- Deirdre Doyle
- Dejan Veličković
- Delmiro Becker
- Delphine Ngo
- Demet Tok Aydin
- Detlef Kindgen-Milles
- Devrim Akdağ
- Deyan Cao
- Diana Alvarez
- Diane Barkas
- Dianne Figaro-Barclay
- Dick Nahar
- Diego Rolando Morocho Tutillo
- Dimitra Lepida
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- Dirk von Lewinski
- Dmitriy Galishevskiy
- Dmitry Sergeev
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- Dominic Carney
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- Dylan De Lange
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- Emma Parkin
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- Federico Gordo
- Federico Iglesias
- Fei Ouyang
- Feifei Chen
- Feifei Luo
- Feifei Zhang
- Fekri Abroug
- Fengling Yang
- Ferdinand Aganon
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- Fernando Baccaro
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- Fernando Lipovesty
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- Fidelina Canete
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- Guoxue He
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- Jie Gao
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- Jingfang Chen
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- JinHui Song
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- Joaquin Aguirre
- Joerg C Schefold
- Joerg C Schefold
- John Adams
- John Prowle
- John Thomas Sanchez Minope
- Jon Davidow
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- Jong-Joon Ahn
- Jonghyun Baek
- Jongmin Lee
- Jordi Adamuz
- Jorge Duerto Alvarez
- Jorge Guerra Herrera
- Jorge Macias Zermeno
- Jorge Marin
- Jorge Pereira
- Jose Emmanuel Palo
- Josep Trenado Alvarez
- Josue Nzarora
- José Alejandro Navarro
- José Ivan Rodriguez de Molina Serrano
- José Manuel Garcia Pena
- José Peral Gutierrez de Ceballos
- José Rojas-Suarez
- Jowena Ibao
- João Cabral
- João Vieira
- Juan Carlos Rivas
- Juan Cata
- Juan Ignacio Torres Gonzalez
- Juan P Romero-Gonzalez
- Juan Sebastian Hernandez
- Juan Wu
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- Judy Enamorado Enamorado
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- Junping Hao
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- Kefang Wang
- Kellie Sosnowski
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- Kewei Liu
- Khaled Al Qawasmeh
- Khalid Abidi
- Khalid Abidi
- Khalid Mahmood Khan Nafees
- Khalid Mahmood Khan Nafees
- Kishore Mangal
- Kit Weng Foong
- Koen De Decker
- Koji Fujimoto
- Konlawij Trongtrakul
- Konlawij Trongtrakul
- Konlawij Trongtratul
- Konstantina Nestora
- Konstantinos Mandis
- Konstantinos Pagioulas
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- Kumi Maruyama
- Kunal Karamchandani
- Kyeongman Jeon
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- Lakshay Bhakhtiani
- Lamia Besbes
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- Lei Chen
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- Leif Saager
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- Lenneke Haas
- Lesia Zgrzheblovska
- Lesia Zgrzheblovska
- Leticia Serpa
- Lettie Van Den Berg
- Li Chuntang Li
- Li Gao
- Li Hong
- Li Ping Hu
- Li Xixi
- Li Yin
- Libing Zhang
- Lidia Glinka
- Lidia Traina
- Liesbet Demarré
- Lihong Liu
- Liivi Maddison
- Liivi Maddison
- Lijuan Zhao
- Lili Hu
- Lili Tuo
- Limei Fan
- Limei Miao
- Lin InSu
- Lina Xiao
- Lina Xu
- Lina Zhao
- Ling Li
- Ling Liu
- Ling Zhang
- LingLing Wang
- Linlin Luan
- LiPing Huang
- Lisa Dunne
- Lisa Høgvall
- Liu Hong
- Liudmila Fadeeva
- Liudmila Grishina
- Liuyan Ge
- Liz Wilby
- Llesley Chadwick
- Lomangisi Dlamini-Sserumaga
- Lorena Del Rio Cabajo
- Lorna Merritt-Charles
- Lorna Merritt-Charles
- Lorraine Thompson
- Losune Cano Sanchez
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- Maarit Ahtiala
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- Madhu Balasubramanian
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- Man Ye
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- Maria Foka
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- Ulla Kesti
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- Umeda Aya
- Una Gunter
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- V Gusarov
- Vaarisan Ganeshalingam
- Vaibhav Bhargava
- Valentina Bendelari
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- Vanda Seromenho
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- Vanesa Mercado Telleria
- Vanja Gievski
- Vanja Misic
- Vasileios Bekos
- Vasiliki Chantziara
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- Vasilios Koulouras
- Veronica Curilen
- Veronika Kotanidi
- Vesna Bumbasirevic
- Vicent Salvà-Costa
- Victor Gonzalez
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- Victoria Marriott
- Vilas Kushare
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- Vincianne Pleitinckx
- Virginie Souppart
- Virpi Lusenius
- Vishnu Das Sasidharan Nair
- Vitaly Gusarev
- Vitaly Gusarov
- Vitor Gomes
- Vitor Manuel Vaz Pinto
- Viveca Hamback Hellkvist
- Višnja Nesek Adam
- Vladimir Gurevich
- Vladimir Kulakov
- Vladislav Belskiy
- Volkan Inal
- Volodymyr Babych
- Vongayi Ogbeide
- W Nazaruddin W Hassan
- Walid Naija
- Walid Sellami
- Walter Swinnen
- Wan Nasrudin Wan Ismail
- Wang Zhijuan
- Wangari Waweru-Siika
- Wangari Waweru-Siika
- Wangyan Jin
- Wei Sun
- Wei Wang
- Wei Wei
- Wei Zhang
- Wei Zhang
- Weilian Yuan
- Weiwei Li
- Wenche Arntsen
- Wendy Brown
- Wendy Chaboyer
- Wendy Chaboyer
- Wendy Milner
- Wenjie Ju
- Wenmei Wang
- Wenmin Chen
- Wenwen Zhao
- Wenzhen Cao
- Wesal Ali Belkhair
- Willem Dieperink
- Windu Baskoro
- Won-Yeon Lee
- Wu Yuchen
- Xia Cui
- Xia Huang
- Xianhong Zheng
- Xianping Luo
- Xiao Fang Tian
- Xiao Xu
- XiaoChun Hu
- Xiaodi Liu
- Xiaofang Luo
- Xiaohan Li
- Xiaohan Li
- Xiaojun Wu
- Xiaoli Yan
- Xiaomin Wang
- Xiaoqiong Deng
- Xiaowu Bai
- Xiaoyan Chen
- Xiaoyan Chen
- Xiaoying Wu
- XiaoZhe Liu
- Ximena Villanueva
- Xingguo Li
- Xinhua Xia
- Xinhua Xia
- Xinjian Li
- Xinran Ding
- Xinxia Li
- Xinxia Li
- Xiuhua Fang
- Xiuhua Fang
- Xiujuan Xue
- XiuMei Liu
- Xiuying Yao
- Xiyan Wei
- Xu Peipei
- Xue Lin
- Xue Qin Li
- Xuejuan Liang
- XueLian Liu
- Xuelian Pang
- Xuelian Xu
- Xueping Jiao
- Yajun Ding
- Yakubu H Yakubu
- Yali Zhang
- Yalım Dikmen
- Yalım Dikmen
- Yalim Dikmen
- Yan Gao
- Yan Li
- Yan Liu
- Yan Liu
- Yan Long
- Yan Wan
- Yan Wang
- Yan Xiao
- Yan Xie
- Yan Xu
- Yan Yan
- Yanfei Long
- Yang Lei
- Yang Liu
- Yang Wu
- Yang Xiaoyan
- Yanhong Di
- Yanhua Hao
- Yani Tian
- Yanlan Yao
- Yanling Shen
- Yanman Jian
- Yanmei Gu
- Yanming Ding
- Yann Le Guen
- Yanping Yang
- Yasser Mandourah
- Yenny Cardenas
- Yenny Cardenas
- Yesim Serife Bayraktar
- Yin He
- Ying Cao
- Ying Li
- Ying Liu
- Ying Wang
- Ying Wei
- Ying Zhang
- Yingjuan Zhao
- Yingli Wang
- Yinhua Guo
- Yolanda Mendiara
- YongXia Yang
- Yoshimasa Nishime
- Yoshiro Hayashi
- Youjin Chang
- Youru Jiang
- Youssef Zied Elhechmi
- Ysica Acosta
- Yu Chao
- Yu Han
- Yu Liu
- Yu Liu
- Yue Sun
- Yue Ying Gong
- Yuming Zhou
- Yun Su Sim
- Yun Wu
- Yunchun Dong
- Yunfeng Xiong
- Yupeng Liu
- Yuping Wang
- Yuxia Huo
- Yuxia Wang
- Yuxia Yuan
- Yvan Fleury
- Yvonne Andersen
- Zainab Ateya
- Zaneta Bogoevska-Miteva
- Zeya Shi
- Zhang Zhigang
- ZhangShuangzi Li
- ZhangXia Feng
- Zhaoxia Feng
- Zhaoxing Dai
- Zhenxia Zhang
- Zhihong Chen
- Zhiru Yao
- Zhixia Jiang
- ZhiXia Jiang
- Zhixia Tian
- Zhu Jun Yu
- Zhuqing Li
- Zied Hajjej
- Zijing Wu
- Zsuzsann Ágoston
- Zu Qing Cao
- Zulkifli Zulkifli
- Ângela Lima
- Publication venue
- Intensive Care Medicine
- Publication date
- 29/08/2020
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
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- Hamid Hytham K. S.
- Hamida Baha Ben
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- Martínez Daniel Fernández
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- Mauriello Claudio
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- Mayer Horacio F.
- Mayo-Yáñez Miguel
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- McPherson Duncan
- Meara John G.
- Meead Adullah
- Mehraj Asif
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- Mengesha Mengistu G.
- Menna Maria Paola
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- Méndez Patricia Serrano
- Nabil Fatma
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- Nacion Aeris Jane D.
- Nadi Khaldoun
- Naegele Felix
- Naga Hani
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- Nankivell Paul
- Naranjo Eddy P. Lincango
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- Nassar Mahmoud A.
- Nasser Sara
- Nastos Constantinos
- Natale Joseph
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- Nevins Edward J.
- Newman Samuel
- Ngaserin Sabrina
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- Niewiera Marc
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- Nitschke Christine
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- Ntalouka Maria P.
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- Oludara Mobolaji
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- Pettigrove K.L.
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- Punjabi Prakash P
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- Pérez Beatriz Gómez
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- Reyes Jeryl Anne Silvia
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- Rhomberg Thomas
- Ribeiro João
- Riccetti Camilla
- Richard H.
- Rickard Jennifer
- Rincón Natalia Andrea Rivera
- Ripollés-Melchor Javier
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- Rodriguez-Lopez Mario
- Rodríguez Lorena Varela
- Rokohl Alexander Christopher
- Roland Christina L
- Rolinger Jens
- Romano Angela
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- Ryan James
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- Sabbagh Abdulrahman J.
- Sabella Danielle
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- Santoshi John Ashutosh
- Santric Veljko
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- Saracoglu Ayten
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- Sayyed Raza
- Scabini Stefano
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- Scafa Anthony Kevin
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- Scaravilli Luca
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- Wade Ryckie
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- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
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- Wright Joshua
- Wu Fiona
- Wurm Markus
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- Yanik Özge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
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- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- Zaránd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha Horácio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ávila Clara Castro
- Älgå Andreas
- Çakici Mehmet Çaǧlar
- Çelik Enes
- Çelik Meryem Nur
- Özçay Necdet
- Şevik Hüsnü
- Šantak Goran
- Šimko Kristián
- Žatecký Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Noninvasive imaging estimation of myocardial iron repletion following administration of intravenous iron: the myocardial-IRON Trial
- Author
- Almenar Luis
- Amiguet Martina
- Bayés Genís Antoni
- Bodí Vicent
- Cardells Ingrid
- Chorro Francisco J.
- Comín Colet Josep
- Espriella-Juan Rafael de la
- Fácila Lorenzo
- García-Blas Sergio
- González Jessika
- Górriz José Luis
- Llàcer Pau
- Lupón Josep
- López Vilella Raquel
- López-Lereu Maria P.
- Miñana Gema
- Monmeneu Jose V.
- Montagud Vicente
- Myocardial‐IRON Investigators
- Navarro Pérez Jorge
- Nuñez Julio
- Palau Patricia
- Sanchis Forés Juan
- Serrano Alicia
- Valero Ernesto
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2020
- Field of study
Background Intravenous ferric carboxymaltose (FCM) improves symptoms, functional capacity, and quality of life in heart failure and iron deficiency. The mechanisms underlying these effects are not fully understood. The aim of this study was to examine changes in myocardial iron content after FCM administration in patients with heart failure and iron deficiency using cardiac magnetic resonance. Methods and Results Fifty-three stable heart failure and iron deficiency patients were randomly assigned 1:1 to receive intravenous FCM or placebo in a multicenter, double-blind study. T2* and T1 mapping cardiac magnetic resonance sequences, noninvasive surrogates of intramyocardial iron, were evaluated before and 7 and 30 days after randomization using linear mixed regression analysis. Results are presented as least-square means with 95% CI. The primary end point was the change in T2* and T1 mapping at 7 and 30 days. Median age was 73 (65-78) years, with N-terminal pro-B-type natriuretic peptide, ferritin, and transferrin saturation medians of 1690 pg/mL (1010-2828), 63 ng/mL (22-114), and 15.7% (11.0-19.2), respectively. Baseline T2* and T1 mapping values did not significantly differ across treatment arms. On day 7, both T2* and T1 mapping (ms) were significantly lower in the FCM arm (36.6 [34.6-38.7] versus 40 [38-42.1], P=0.025; 1061 [1051-1072] versus 1085 [1074-1095], P=0.001, respectively). A similar reduction was found at 30 days for T2* (36.3 [34.1-38.5] versus 41.1 [38.9-43.4], P=0.003), but not for T1 mapping (1075 [1065-1085] versus 1079 [1069-1089], P=0.577). Conclusions In patients with heart failure and iron deficiency, FCM administration was associated with changes in the T2* and T1 mapping cardiac magnetic resonance sequences, indicative of myocardial iron repletion. Clinical Trial Registration URL: http://www.clinicaltrials.gov. Unique identifier: NCT03398681
The Canfranc Axion Detection Experiment (CADEx): Search for axions at 90 GHz with Kinetic Inductance Detectors
- Author
- 0000-0001-9643-5479
- 0000-0002-4603-2273
- 0000-0003-1371-0610
- 0000-0003-2933-1471
- Aja Beatriz
- Arguedas Cuendis Sergio
- Artal Eduardo
- Barreiro R. Belén
- Casas Francisco J.
- Díaz-Morcillo Alejandro
- Fuente Luisa de la
- Gallego Juan Daniel
- García-Barceló José María
- Gimeno Benito
- Granados Daniel
- Gómez Alicia
- Kavanagh Bradley J.
- Lopetegui Beregaña José María
- Lozano-Guerrero Antonio José
- Magaz María T.
- Martín-Pintado Jesús
- Martínez-González Enrique
- Miralda-Escudé Jordi
- Monzó-Cabrera Juan
- Najarro de la Parra Francisco
- Navarro-Madrid José R.
- Nuñez Chico Ana B.
- Ory Marina C. de
- Pascual Juan Pablo
- Pelegrin Jorge
- Peña Garay Carlos
- Rodríguez David
- Socuéllamos Juan M.
- Vielva Patricio
- Vila Iván
- Vilar Rocío
- Villa Enrique
- Publication venue
- Publication date
- 01/01/2022
- Field of study
We propose a novel experiment, the Canfranc Axion Detection Experiment
(CADEx), to probe dark matter axions with masses in the range 330-460 μeV,
within the W-band (80-110 GHz), an unexplored parameter space in the
well-motivated dark matter window of Quantum ChromoDynamics (QCD) axions. The
experimental design consists of a microwave resonant cavity haloscope in a high
static magnetic field coupled to a highly sensitive detecting system based on
Kinetic Inductance Detectors via optimized quasi-optics (horns and mirrors).
The experiment is in preparation and will be installed in the dilution
refrigerator of the Canfranc Underground Laboratory. Sensitivity forecasts for
axion detection with CADEx, together with the potential of the experiment to
search for dark photons, are presented.Comment: 23 pages, 10 figure