Pendugaan Cadangan Karbon Di Atas Permukaan Pada Hutan Rakyat Dengan Memanfaatkan Data Synthetic Aperture Radar Sentinel-1 (Studi Kasus Di Kabupaten Sukoharjo)

The high amount of carbon dioxide in the atmosphere is one of the causes of global warming. Preserve carbon stocks is an effort to reduce carbon emissions, including in the community forest which need to be recorded. Remote Sensing Data of Sentinel-1 SAR (Synthetic Aperture Radar) was used to determine the above ground carbon stocks on community forest in Sukoharjo Regency. The objectives of this reasearh are: 1) analyze the relationship between the backscatter value of Sentinel-1 SAR dual polarization data and the value of carbon stock in community forest based on the above ground green biomass value; 2) to estimate above ground carbon stock of community forest in Sukoharjo Regency by utilizing the dual-polarization SAR Sentinel-1 data; and 3) to determine the total and the spatial distribution of above ground carbon stock on community forest in Sukoharjo Regency based on Sentinel-1 SAR data. The method was used in this study is a survey method using purposive sampling to complement remote sensing data related to biomass and above ground carbon stock in community forest using allometric equations based on the the extraction result of backscatter value of each polarization VV (Vertical-Vertical), VH (Vertical-Horizontal), and band ratio VV/VH. Statistical analysis was used to generate equation for estimating carbon stocks based on the SAR data and field data. Geographic Information System (GIS) was used to represent data spatially well as information of above ground carbon stock value and used spatial data analysis approach both quantitatively and qualitatively. The results showed that: 1) there is a significant and inversely relationship between the value of VV polarization backscatter (R = -0.438 (very low)) and VH polarization (R = -0.612 (Low)) on above graound carbon stock value. 2) How to Estimate Above ground carbon stock on community forest in Sukoharjo was obtained from Sentinel-1 SAR data using VH polarization with chosen simple linear regression equation (R2 = 0.375; RMSE = 101.1648) is Y = -61.499 -493.268 + X. The Total of above ground carbon stock in Sukoharjo Regency is 228,456.36 tons of 7738.287 hectares community forest and it has a spread spatial distribution pattern at random and clustered. The largest above ground biomass carbon stock is in the community forest of Bulu Sub-district is 49540.21 tons (1782.008 ha) and least in the Gatak Sub-district is 49.50 tons (1,357 ha)

Solitary fibrous tumour of the submandibular region: a rare entity

Solitary fibrous tumours of the head and neck region are extremely rare. The clinical diagnosis is often difficult to establish, and this lesion may be indistinguishable from other soft tissue neoplasms. An 18-year old Chinese gentleman presented with a painless right submandibular swelling which was increasing in size for eight months. A computed tomography scan showed a well-defined solid mass measuring about 2.0 x 2.96 cm in the submandibular region. The tumour was resected and was confined within its capsule. Immunohistochemical staining was strongly positive for CD34, CD 99, and vimentin and negative for desmin, smooth muscle actin (SMA), cytokeratin, S100 and CD68. The microscopic and immunohistochemical profile were compatible with solitary fibrous tumour. Distinguishing solitary fibrous tumours from various spindle neoplasms can be difficult. In view of the resemblance, immunohistochemical staining can help differentiate solitary fibrous tumour from spindle neoplasm

FREQUENCY OF BONE FRACTURES DETECTED BY PLAIN RADIOGRAPHY AND KEEPING CT AS GOLD STANDARD

Background: The main cause of bone fracture is traffic accidents are (72.2%), falls (11.6%), blunt injuries are (7.7%) and others (5.8%)). About 84 patients were included in our studies. Out of which 21 (25.0%) were females and 63(75.0%) were males. Objective: The objective of this study is to evaluate the frequency of bone fractures detected by plain radiography and keeping CT as gold standard. Methodology: In our cross-sectional study all the patients with fracture undergoing CT and X-Ray were included. Patients with bone surgery were excluded as well as patients who declined to give consent and those who were uncooperative were all excluded. X-ray performed for all the fractures and the complex one sent to CT. The consent form was obtained by patients in this study. We reviewed our data of patients who underwent CT and X-ray. CT (Toshiba 64) was performed from the exact area of fracture and images reconstructed at 3mm and for reporting 5mm for filming. X-ray performed according to the appropriate range of kVp and mAs. All findings of CT were considered by the advice of consultant radiologist. Data was represented with means of standard deviation of frequency and percentage where appropriate. Chi square testing was used to compare CT and X-ray qualitative data. Data was entered into IBM SPSS Statistics 24.0. P-value <0.05 considered the significant. Results: In our study 84 patients were included. Out of which 21 (25.0%) were females and 63 (75.0%) were males and the standard deviation was 0.436. There causes of fracture were 18(21.4%) injury, 8(9.5%) were compression fractures, 54(64.3%) RTA, 2(2.4%) pathologic fractures and 1(1.2%) was sports injury fracture and the standard deviation was .997. Conclusion: Our study concluded that the bone fractures are more common in males than females. The most common cause of bone fractures is RTA (Road Traffic Accidents). Study also concludes that most common type of bone fracture is Transverse bone fracture. CT was more efficient in detecting bone fractures than plain radiography because more fractures were detected on CT than plain radiography. Keywords: Non-enhanced CT, X- ray, Bone fracture, Road Traffic Accidents DOI: 10.7176/JHMN/93-09 Publication date:September 30th 202

Diagnostic Accuracy of Ultrasound for the Evaluation of Ureteric Calculi Taking Non-enhanced Computed Tomography as a Gold Standard

Objective: To find the diagnostic accuracy of ultrasound for the evaluation of ureteric calculi taking non enhanced Computed Tomography as gold standard. Study Design: An analytical cross-sectional prospective study was performed. Settings: The study was performed in National Hospital and Medical Center, Lahore. Period: An analytical cross-sectional study was conducted from 15 October, 2020 to 15 January, 2021. Material & Methods: In our study, all those patients with suspected ureteric calculi presenting to radiology department were included. Patients on dialysis, those with polycystic disease and ureteric stricture, as well as patients who declined to give consent and those who were uncooperative, were all excluded. Ultrasound was performed on both sides of the patient's kidney, concentrating on the ureters. Then were sent to a 64 slice CT scanner for a non-enhanced CT scan. Results: Total 121 Patients were reviewed in this research. Females were 82 (67.8%) while male was 39 (32.2%). On Ultrasound 61(50.4%) were positive for ureteric calculi while 60 (49.6%) were negative for stone in the ureter. On CT scan 110 (90.9%) patients were positive for ureteric calculi while 11 (9.1%) were negative for stone in ureter (p= 0.05). The trans-abdominal ultrasound with sensitivity 58.62%, Specificity 56.76%, Positive predictive value 51.52% and Negative predictive value of 63.64% and accuracy of 57.68%. Conclusion: The sensitivity of ultrasound is comparable to Computed Tomography findings, hence, it can be used as an option in cases where CT scans are not available or is contraindicated, such as in pregnant women. Moreover, Ultrasound modality is cheap, with no radiation dose and is readily available in our setups, making it suitable for initial diagnosis as well as for follow-up scans. Keywords: Non-enhanced Computed Tomography, Ultrasound, Ureteric Calculi, radiation, Computed Tomography. DOI: 10.7176/JHMN/90-04 Publication date:June 30th 2021

Sonographic Evaluation of Cholelithiasis and Its Correlation with Normal/Fatty Liver

Cholelithiasis and Fatty Liver disease are usually observed to coexist. Patients who have gallstones also have Fatty Liver as both of the conditions have same associated risk factors I.e., diabetes mellitus, gender, age, obesity, metabolic syndrome, insulin resistance and high lipids level. Non-Alcoholic Fatty Liver Disease (NAFLD) is also an independent accountable risk factor for the formation of gallstones. We aimed to determine whether there is any correlation between cholelithiasis and fatty liver disease. The study was conducted in Lahore General Hospital, Lahore, Pakistan. The data was collected from March 24,2021 to May 24,2021. Informed consent was taken from all the participants. We did a cohort study comprising the data of 51 patients undergoing physical checkup. The data gathered included age, gender and whether they had normal or fatty liver. Cholelithiasis was diagnosed by confirming the presence of gallstones on abdominal ultrasonography after fasting for approximately 8hrs. it was an observational study for the assessment of correlation between cholelithiasis and fatty liver in the participants. A Total of 51 patients with cholelithiasis were included in our study. Most of the patients were 29 to 70 years of age. The average age of the patients was 42.3 ± 10.1 years. Out of 51 patients, there were 60.8% (P=31) females and 39.2%(P=20) males. Out of 51 cholelithiasis patients there were 31.4%(P=16) had Normal Liver and 68.6%(P=35) were positive with Fatty liver disease. Patients with stone size ranges from 1.90mm to 4.6mm hade Grade 1 Fatty liver as shown in table-5.4, Grade 2 Fatty liver was seen in patients with stone size ranges from 4.5mm to 5.8mm. Fatty liver Grade 3 was not observed in any included patient with cholelithiasis. Results of our study showed that both cholelithiasis and Fatty Liver disease are correlated with each other. Females are at higher risk to be affected by these with diseases. Early detection of Fatty liver in patients of cholelithiasis can help patients to prevent them further complications regarded to fatty liver and cholelithiasis and can play important role in health care of society. Keywords: Non-Alcoholic Fatty Liver Disease, Cholelithiasis, Fatty liver, Ultrasonography. DOI: 10.7176/JHMN/91-07 Publication date:July 31st 202

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

The global burden of cancer attributable to risk factors, 2010-19 : a systematic analysis for the Global Burden of Disease Study 2019

Background Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings Globally, in 2019, the risk factors included in this analysis accounted for 4.45 million (95% uncertainty interval 4.01-4.94) deaths and 105 million (95.0-116) DALYs for both sexes combined, representing 44.4% (41.3-48.4) of all cancer deaths and 42.0% (39.1-45.6) of all DALYs. There were 2.88 million (2.60-3.18) risk-attributable cancer deaths in males (50.6% [47.8-54.1] of all male cancer deaths) and 1.58 million (1.36-1.84) risk-attributable cancer deaths in females (36.3% [32.5-41.3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20.4% (12.6-28.4) and DALYs by 16.8% (8.8-25.0), with the greatest percentage increase in metabolic risks (34.7% [27.9-42.8] and 33.3% [25.8-42.0]). Interpretation The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

BACKGROUND: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. METHODS: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. FINDINGS: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01–4·94) deaths and 105 million (95·0–116) DALYs for both sexes combined, representing 44·4% (41·3–48·4) of all cancer deaths and 42·0% (39·1–45·6) of all DALYs. There were 2·88 million (2·60–3·18) risk-attributable cancer deaths in males (50·6% [47·8–54·1] of all male cancer deaths) and 1·58 million (1·36–1·84) risk-attributable cancer deaths in females (36·3% [32·5–41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6–28·4) and DALYs by 16·8% (8·8–25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9–42·8] and 33·3% [25·8–42·0]). INTERPRETATION: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden