Characteristics of specialists treating hypothyroid patients:the “THESIS” collaborative

Introduction: Thyroid specialists influence how hypothyroid patients are treated, including patients managed in primary care. Given that physician characteristics influence patient care, this study aimed to explore thyroid specialist profiles and associations with geo-economic factors. Methods: Thyroid specialists from 28 countries were invited to respond to a questionnaire, Treatment of Hypothyroidism in Europe by Specialists: an International Survey (THESIS). Geographic regions were defined according to the United Nations Statistics Division. The national economic status was estimated using World Bank data on the gross national income per capita (GNI per capita). Results: 5,695 valid responses were received (response rate 33·0%). The mean age was 49 years, and 65·0% were female. The proportion of female respondents was lowest in Northern (45·6%) and highest in Eastern Europe (77·2%) (p &lt;0·001). Respondent work volume, university affiliation and private practice differed significantly between countries (p&lt;0·001). Age and GNI per capita were correlated inversely with the proportion of female respondents (p&lt;0·01). GNI per capita was inversely related to the proportion of respondents working exclusively in private practice (p&lt;0·011) and the proportion of respondents who treated &gt;100 patients annually (p&lt;0·01). Discussion: THESIS has demonstrated differences in characteristics of thyroid specialists at national and regional levels, strongly associated with GNI per capita. Hypothyroid patients in middle-income countries are more likely to encounter female thyroid specialists working in private practice, with a high workload, compared to high-income countries. Whether these differences influence the quality of care and patient satisfaction is unknown, but merits further study.</p

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Structural response of hybrid timber ‐ cold formed steel floors

The paper examines the composite performance of hybrid steel-timber lightweight floor assemblies incorporating cold-formed steel (CFS) profiles and plywood (PW) flooring panels with varying degrees of shear connection achieved by means of self-drilling screws. Material, push-out, and three-point short-span floor tests with or without web openings were carried out. The results and observations from the tests provide a detailed insight into the inelastic properties and ultimate response of such floor systems. Push-out tests indicate that denser connector arrangements increase connection stiffness, while push-out and short beam tests suggest an optimum connector spacing equal to the beam depth for a balance between structural performance and constructability. The experimental observations indicate that the ultimate condition of the short composite beams was characterized by CFS web crippling under the load application point, followed by a pull-through of the self-drilling screws. Web openings reduced the strength of the floor elements compared to the members with full webs. Complementary numerical studies are undertaken using nonlinear finite element procedures which were validated against the beam tests, offering a detailed insight into the stress levels in the timber, steel, and connectors. Codified procedures for determining the capacity of composite CFS sections are compared with the test results, and guidance for the practical design and construction of such systems is given

Sustainability challenges of residential reinforced-concrete panel buildings

Quite similar large-panel prefabrication technologies were used for residential buildings in East-Europe and some countries in Northern-Europe, e.g. Finland. Even if technologically similar, the fate of the building stocks is different in the two regions, with buildings functioning sustainably in Finland. Hence, one could adapt the maintenance and renovation experiences to the building stock in other countries, creating opportunities for communities and business. The paper presents technological, economical, and institutional/policy aspects in the two environments, and discusses them in the larger framework of European sustainability targets. For major renovation, as targeted in the paper, methods of change management should be applied, entailing thoughtful planning and sensitive implementation and above all, consultation/involvement of the people affected. If the presented interventions would be used in a systematic and planned way, improvements can be achieved for social sustainability targets like e.g. adaptability and visual comfort, while maintaining the safety and security. Finally, the limitations of the approach in light of the institutional setting and ownership structure are discussed, highlighting how different ownership models are favoring or hindering major retrofit interventions. The paper offers ways on strengthening the role of key stakeholders to support major renovation interventions on the panel building stock

Seroprevalence of Toxoplasma gondii in wild boars, red deer and roe deer in Poland

Little is known about the prevalence of Toxoplasma gondii in wild life, particularly game animals in Poland. Meat juice collected during the 2009/2010 and 2010/2011 hunting seasons from 552 red deer (Cervus elaphus), 367 wild boars (Sus scrofa) and 92 roe deer (Capreolus capreolus) was tested for T. gondii antibodies using the multi-species ID Screen Toxoplasmosis Indirect kit (IDvet, Montpellier, France). Antibodies to T. gondii were detected in 24.1% of red deer (95% CI: 20.7%, 27.8%), 37.6% of wild boar (95% CI: 32.8%, 42.7%) and 30.4% of roe deer (95% CI: 22.0%, 40.5%). To the authors’ best knowledge, this is the first epidemiological report of T. gondii prevalence in red deer, roe deer and wild boars in Poland. T. gondii is present in wildlife animal tissues and consumption of the game may be a potential source of infection for humans

Seroprevalence of

Little is known about the prevalence of Toxoplasma gondii in wild life, particularly game animals in Poland. Meat juice collected during the 2009/2010 and 2010/2011 hunting seasons from 552 red deer (Cervus elaphus), 367 wild boars (Sus scrofa) and 92 roe deer (Capreolus capreolus) was tested for T. gondii antibodies using the multi-species ID Screen Toxoplasmosis Indirect kit (IDvet, Montpellier, France). Antibodies to T. gondii were detected in 24.1% of red deer (95% CI: 20.7%, 27.8%), 37.6% of wild boar (95% CI: 32.8%, 42.7%) and 30.4% of roe deer (95% CI: 22.0%, 40.5%). To the authors’ best knowledge, this is the first epidemiological report of T. gondii prevalence in red deer, roe deer and wild boars in Poland. T. gondii is present in wildlife animal tissues and consumption of the game may be a potential source of infection for humans