176 research outputs found
Thin films produced on 5052 aluminum alloy by plasma electrolytic oxydation with Red Mud-containing Electrolytes
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Produções tecnológicas em enfermagem em um curso de mestrado
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Alternative splicing enriched cDNA libraries identify breast cancer-associated transcripts
- Author
- A Nardi
- A Watahiki
- AC Stamps
- B Modrek
- BMN Brinkman
- BP Lewis
- CC Kumar
- CV Jongeneel
- D Slamon
- Dirce M Carraro
- DJ Slamon
- DL Black
- E Chastre
- Elisa N Ferreira
- EN Ferreira
- ET Wang
- F Bartel
- FC Chen
- FR Hsu
- G Thill
- Gustavo C Molina
- J Albanell
- J Harrow
- J Tazi
- J Xu
- J Yi
- JC Castle
- JL Fiori
- JM Johnson
- Jorge E de Souza
- JP Venables
- JP Venables
- JP Venables
- K Yura
- L Diatchenko
- L Florea
- L Hui
- M Cuperlovic-Culf
- M Matz
- M Mukherji
- M Zavolan
- Maria CR Rangel
- MF Press
- ML dos Santos
- N Kirschbaum-Slager
- PA Galante
- Pedro F Galante
- PJ Gardina
- Q Pan
- RA Harris
- RA Holt
- RE Green
- S Maere
- Sandro J de Souza
- V Glisin
- W Gilbert
- WJ Kent
- X Huang
- Y Wang
- Y Xing
- Z Jiang
- Z Kan
- Publication venue
- BioMed Central
- Publication date
- 01/01/2010
- Field of study
<p>Abstract</p> <p>Background</p> <p>Alternative splicing (AS) is a central mechanism in the generation of genomic complexity and is a major contributor to transcriptome and proteome diversity. Alterations of the splicing process can lead to deregulation of crucial cellular processes and have been associated with a large spectrum of human diseases. Cancer-associated transcripts are potential molecular markers and may contribute to the development of more accurate diagnostic and prognostic methods and also serve as therapeutic targets. Alternative splicing-enriched cDNA libraries have been used to explore the variability generated by alternative splicing. In this study, by combining the use of trapping heteroduplexes and RNA amplification, we developed a powerful approach that enables transcriptome-wide exploration of the AS repertoire for identifying AS variants associated with breast tumor cells modulated by <it>ERBB2</it> (<it>HER-2/neu</it>) oncogene expression.</p> <p>Results</p> <p>The human breast cell line (C5.2) and a pool of 5 ERBB2 over-expressing breast tumor samples were used independently for the construction of two AS-enriched libraries. In total, 2,048 partial cDNA sequences were obtained, revealing 214 alternative splicing sequence-enriched tags (ASSETs). A subset with 79 multiple exon ASSETs was compared to public databases and reported 138 different AS events. A high success rate of RT-PCR validation (94.5%) was obtained, and 2 novel AS events were identified. The influence of <it>ERBB2</it>-mediated expression on AS regulation was evaluated by capillary electrophoresis and probe-ligation approaches in two mammary cell lines (Hb4a and C5.2) expressing different levels of <it>ERBB2</it>. The relative expression balance between AS variants from 3 genes was differentially modulated by <it>ERBB2</it> in this model system.</p> <p>Conclusions</p> <p>In this study, we presented a method for exploring AS from any RNA source in a transcriptome-wide format, which can be directly easily adapted to next generation sequencers. We identified AS transcripts that were differently modulated by <it>ERBB2</it>-mediated expression and that can be tested as molecular markers for breast cancer. Such a methodology will be useful for completely deciphering the cancer cell transcriptome diversity resulting from AS and for finding more precise molecular markers.</p
Leishmaniose tegumentar americana no Litoral Norte Paulista, período 1993 a 2005
- Author
- Azeredo-Coutinho RBG
- Basano SA
- Brito M
- Chaves LF
- Condino MLF
- Desjeux P
- Diogo Correa da Silva
- Domingos MF
- Eunice Aparecida Bianchi Galati
- Franke CR
- Galati EAB
- Gomes AC
- Kawa H
- Maria Lúcia Fadel Condino
- Maria Rafaela Braga Salum
- Marzochi MCA
- Márcia Moreira Holcman
- Paiva BR
- Petney TN
- Pita-Pereira D
- Rangel EF
- René Antonio Novaes Júnior
- Rojas CA
- Soares VB
- Tolezano JE
- Tolezano JE
- Tolezano JE
- Vanzeli AC
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Decellularized Matrix from Tumorigenic Human Mesenchymal Stem Cells Promotes Neovascularization with Galectin-1 Dependent Endothelial Interaction
- Author
- A De Luca
- A Gaultier
- A Semov
- A Shiga
- A Valentine
- AA Rose
- AG Arroyo
- AG Hovanessian
- AL Bauer
- AR Braden
- B St Croix
- BM Abdallah
- C Jean
- C Nadalutti
- C Schlueter
- C Ward
- CL Chen
- CM Ghajar
- CR Ireson
- CS Chen
- CW Cheng
- D Destouches
- D Palmieri
- D Virgintino
- DE Ingber
- DW van der Schaft
- E Manevich
- E Myrsky
- E Potier
- E Rieder
- EJ Arnoys
- EL Spaeth
- F Boraldi
- F Bougatef
- G Carmona
- G Grieb
- G Hu
- G Klein
- G Neufeld
- GE Davis
- H Zhang
- Helle Christiansen
- I Camby
- I Fierro-Monti
- I Rosova
- J Rappsilber
- J Wang
- J Wang
- J Zhang
- JA DeQuach
- JA Semon
- Jan Nehlin
- JE Reing
- Jens S. Andersen
- JL Lin
- JL Simonsen
- JM Sorrell
- Jorge S. Burns
- JS Burns
- JS Burns
- JS Silvestre
- K Mitchell
- Kenneth H. Larsen
- KJ Daniels
- KK Graven
- L Primo
- Lars P. Kristensen
- M Corselli
- M De Palma
- M Irigoyen
- M Kotecki
- M Le Mercier
- M Leifheit-Nestler
- M Leis
- M Loi
- M Ruhl
- M Zanetti
- Malthe Kristiansen
- Maria O. Nielsen
- ME Francis
- MF Bolontrade
- MG Magagnin
- MJ Bissell
- Moustapha Kassem
- N Akhtar
- N Clausse
- N Riggi
- N Serakinci
- NF Huang
- P Au
- P Bornstein
- P Macchiarini
- P Saharinen
- PA Soucy
- PS Zheng
- R del Toro
- R Korn
- R Rangel
- R Silva
- RD Meyer
- RJ Pasterkamp
- RM Young
- RO Hynes
- RO Hynes
- Roger Chammas
- RP Dings
- RV Iozzoa
- S Abraham
- S Bohman
- S Keerl
- S Schandorff
- SG DuBois
- SH Hsieh
- T Kadri
- T Korff
- TH Chun
- TN Demidova-Rice
- V Nehls
- VL Ballard
- VM Cardenas Delgado
- VW van Hinsbergh
- W Cai
- WF Liu
- Y Huang
- Y Inagaki
- Y Kubota
- YS Maeng
- Z Gong
- Z Zhou
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
BACKGROUND: Acquisition of a blood supply is fundamental for extensive tumor growth. We recently described vascular heterogeneity in tumours derived from cell clones of a human mesenchymal stem cell (hMSC) strain (hMSC-TERT20) immortalized by retroviral vector mediated human telomerase (hTERT) gene expression. Histological analysis showed that cells of the most vascularized tumorigenic clone, -BD11 had a pericyte-like alpha smooth muscle actin (ASMA+) and CD146+ positive phenotype. Upon serum withdrawal in culture, -BD11 cells formed cord-like structures mimicking capillary morphogenesis. In contrast, cells of the poorly tumorigenic clone, -BC8 did not stain for ASMA, tumours were less vascularized and serum withdrawal in culture led to cell death. By exploring the heterogeneity in hMSC-TERT20 clones we aimed to understand molecular mechanisms by which mesenchymal stem cells may promote neovascularization. METHODOLOGY/PRINCIPAL FINDINGS: Quantitative qRT-PCR analysis revealed similar mRNA levels for genes encoding the angiogenic cytokines VEGF and Angiopoietin-1 in both clones. However, clone-BD11 produced a denser extracellular matrix that supported stable ex vivo capillary morphogenesis of human endothelial cells and promoted in vivo neovascularization. Proteomic characterization of the -BD11 decellularized matrix identified 50 extracellular angiogenic proteins, including galectin-1. siRNA knock down of galectin-1 expression abrogated the ex vivo interaction between decellularized -BD11 matrix and endothelial cells. More stable shRNA knock down of galectin-1 expression did not prevent -BD11 tumorigenesis, but greatly reduced endothelial migration into -BD11 cell xenografts. CONCLUSIONS: Decellularized hMSC matrix had significant angiogenic potential with at least 50 angiogenic cell surface and extracellular proteins, implicated in attracting endothelial cells, their adhesion and activation to form tubular structures. hMSC -BD11 surface galectin-1 expression was required to bring about matrix-endothelial interactions and for xenografted hMSC -BD11 cells to optimally recruit host vasculature
Development of a virtual learning environment for cardiorespiratory arrest training
- Author
- Alexandre Ribeiro da Silva
- Alves JM
- Amestoy SC
- Anazilda Carvalho da Silva
- Andrea Bernardes
- Camila Santana Justo Cintra Sampaio
- Cook DA
- Dal Sasso GTM
- Dwyer TA
- Filatro A
- Galvis Panqueva A
- Gonzalez MM
- Kleinman ME
- Maria Célia Barcellos Dalri
- Moyer AR
- Oliveira SND
- Pereira IM
- Pereira MCA
- Polit DF
- Prado C
- Rangel EML
- Rodrigues RCV
- Sanson G
- Schifferdecker KE
- Semeraro F
- Vancini-Campanharo CR
- Xelegati R
- Yolanda Dora Martinez Évora
- Évora YDM
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Measurement of the inelastic proton-proton cross section at √s=13 TeV with the ATLAS detector at the LHC
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Abeloos B
- Aben R
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya BS
- Adamczyk L
- Adams DL
- Adelman J
- Adomeit S
- Adye T
- Affolder AA
- Agatonovic-Jovin T
- Agricola J
- Aguilar-Saavedra JA
- Ahlen SP
- Ahmadov F
- Aielli G
- Akerstedt H
- Akesson TPA
- Akimov AV
- Alberghi GL
- Albert J
- Albrand S
- Alconada Verzini MJ
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexopoulos T
- Alhroob M
- Ali B
- Aliev M
- Alimonti G
- Alison J
- Alkire SP
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Alstaty M
- Alvarez Piqueras D
- Alviggi MG
- Amadio BT
- Amako K
- Amaral Coutinho Y
- Amelung C
- Amidei D
- Amor Dos Santos SP
- Amorim A
- Amoroso S
- Amundsen G
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anders JK
- Anderson KJ
- Andreazza A
- Andrei V
- Angelidakis S
- Angelozzi I
- Anger P
- Angerami A
- Anghinolfi F
- Anisenkov AV
- Anjos N
- Annovi A
- Antel C
- Antonelli M
- Antonov A
- Anulli F
- Aoki M
- Arabidze G
- Arai Y
- Araque JP
- Araya ST
- Arce ATH
- Arduh FA
- Arguin J-F
- Argyropoulos S
- Arik M
- Armadans RC
- Armbruster AJ
- Armitage LJ
- Arnaez O
- Arnold H
- Arratia M
- Arslan O
- Artamonov A
- Artoni G
- Artz S
- Asai S
- Asbah N
- Ashkenazi A
- Asman B
- Asquith L
- Assamagan K
- Astalos R
- Astigarraga MEP
- Atkinson M
- Atlay NB
- Augsten K
- Avolio G
- Axen B
- Ayoub MK
- Azuelos G
- Baak MA
- Baas AE
- Baca MJ
- Bachacou H
- Bachas K
- Backes M
- Backhaus M
- Bagiacchi P
- Bagnaia P
- Bai Y
- Baines JT
- Baker OK
- Baldin EM
- Balek P
- Balestri T
- Balli F
- Balunas WK
- Banas E
- Banerjee S
- Bannoura AAE
- Barajas CAC
- Barak L
- Barberio EL
- Barberis D
- Barbero M
- Barillari T
- Barisits M-S
- Barklow T
- Barlow N
- Barnes SL
- Barnett BM
- Barnett RM
- Barnovska Z
- Baroncelli A
- Barone G
- Barr AJ
- Barranco Navarro L
- Barreiro F
- Bartoldus R
- Barton AE
- Bartos P
- Basalaev A
- Bassalat A
- Bates RL
- Batista SJ
- Batley JR
- Battaglia M
- Bauce M
- Bauer F
- Bawa HS
- Beacham JB
- Beattie MD
- Beau T
- Beauchemin PH
- Bechtle P
- Beck HP
- Becker K
- Becker M
- Beckingham M
- Becot C
- Beddall A
- Beddall AJ
- Bednyakov VA
- Bedognetti M
- Bee CP
- Beemster LJ
- Beermann TA
- Begel M
- Behr JK
- Belanger-Champagne C
- Bell AS
- Bella G
- Bella LA
- Bellagamba L
- Bellerive A
- Bellomo M
- Belotskiy K
- Beltramello O
- Belyaev NL
- Benary O
- Benchekroun D
- Bender M
- Bendtz K
- Benekos N
- Benhammou Y
- Benitez J
- Benjamin DP
- Bensinger JR
- Bentvelsen S
- Beresford L
- Beretta M
- Berge D
- Berger N
- Beringer J
- Berlendis S
- Berlingen JM
- Bernard NR
- Bernius C
- Bernlochner FU
- Berry T
- Berta P
- Bertella C
- Bertoli G
- Bertolucci F
- Bertram IA
- Bertsche C
- Bertsche D
- Besjes GJ
- Bessner M
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- Betancourt C
- Bethani A
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- Bevan AJ
- Bianchi RM
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- Biebel O
- Biedermann D
- Bielski R
- Biesuz NV
- Biglietti M
- Billoud TRV
- Bilokon H
- Bindi M
- Binet S
- Bingul A
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- Bisanz T
- Bjergaard DM
- Black CW
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- Blackburn D
- Blair RE
- Blanchard J-B
- Blazek T
- Bloch I
- Blocker C
- Blum W
- Blumenschein U
- Blunier S
- Bobbink GJ
- Bobrovnikov VS
- Bocchetta SS
- Bocci A
- Bock C
- Boehler M
- Boeriu OEV
- Boerner D
- Bogaerts JA
- Bogavac D
- Bogdanchikov AG
- Bohm C
- Boisvert V
- Bokan P
- Bold T
- Boldyrev AS
- Bomben M
- Bona M
- Boonekamp M
- Borisov A
- Borissov G
- Bortfeldt J
- Bortoletto D
- Bortolotto V
- Bos K
- Boscherini D
- Bosman M
- Bossio Sola JD
- Boudreau J
- Bouffard J
- Bouhova-Thacker EV
- Boumediene D
- Bourdarios C
- Boutle SK
- Boveia A
- Boyd J
- Boyko IR
- Bracinik J
- Brandt A
- Brandt G
- Brandt O
- Bratzler U
- Brau B
- Brau JE
- Braun HM
- Bravo AG
- Brendlinger K
- Brennan AJ
- Brenner L
- Brenner R
- Bressler S
- Bret MC
- Bristow TM
- Britton D
- Britzger D
- Brochu FM
- Brock I
- Brock R
- Brooijmans G
- Brooks T
- Brooks WK
- Brosamer J
- Brost E
- Broughton JH
- Bruncko D
- Bruneliere R
- Bruni A
- Bruni G
- Bruni LS
- Brunt BH
- Bruschi M
- Bruscino N
- Bryant P
- Bryngemark L
- Buanes T
- Buat Q
- Buchholz P
- Buckley AG
- Budagov IA
- Buehrer F
- Buescher D
- Buescher V
- Bugge MK
- Bulekov O
- Bullock D
- Burckhart H
- Burdin S
- Burgard CD
- Burghgrave B
- Burka K
- Burke S
- Burmeister I
- Burr JTP
- Busato E
- Bussey P
- Butler JM
- Buttar CM
- Butterworth JM
- Butti P
- Buttinger W
- Buzatu A
- Buzykaev AR
- Bylund OB
- Cabrera Urban S
- Caforio D
- Cairo VM
- Cakir O
- Calace N
- Calafiura P
- Calandri A
- Calderini G
- Calfayan P
- Callea G
- Caloba LP
- Calvente Lopez S
- Calvet D
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- Calvet TP
- Camarda S
- Camarri P
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- Campana S
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- Camplani A
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- Canale V
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- Cantero J
- Cantrill R
- Cao T
- Caprini I
- Caprini M
- Capua M
- Caputo R
- Carbone RM
- Cardarelli R
- Cardillo F
- Carli I
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- Carlino G
- Carminati L
- Caron S
- Carquin E
- Carrillo-Montoya GD
- Carter JR
- Carvalho J
- Casadei D
- Casado MP
- Casolino M
- Casper DW
- Castaneda-Miranda E
- Castelijn R
- Castelli A
- Castillo Gimenez V
- Castillo IS
- Castillo LRF
- Castro NF
- Catinaccio A
- Catmore JR
- Cattai A
- Caudron J
- Cavaliere V
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- Cavalli D
- Cavalli-Sforza M
- Cavasinni V
- Ceradini F
- Cerda Alberich L
- Cerio BC
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cerv M
- Cervelli A
- Cetin SA
- Chafaq A
- Chakraborty D
- Chan SK
- Chan YL
- Chang P
- Chapman JD
- Charlton DG
- Chatterjee A
- Chau CC
- Che S
- Cheatham S
- Chegwidden A
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chelstowska MA
- Chen C
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- Chen S
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- Chen X
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- Cheng HC
- Cheng HJ
- Cheng Y
- Cheplakov A
- Cheremushkina E
- Cherkaoui El Moursli R
- Chernyatin V
- Cheu E
- Chevalier L
- Chiarella V
- Chiarelli G
- Chiodini G
- Chisholm AS
- Chitan A
- Chizhov MV
- Choi K
- Chomont AR
- Chouridou S
- Chow BKB
- Christodoulou V
- Chromek-Burckhart D
- Chudoba J
- Chuinard AJ
- Chwastowski JJ
- Chytka L
- Ciapetti G
- Ciftci AK
- Cinca D
- Cindro V
- Cioara IA
- Ciocca C
- Ciocio A
- Cirotto F
- Citron ZH
- Citterio M
- Ciubancan M
- Clark A
- Clark BL
- Clark MR
- Clark PJ
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- Clement C
- Coadou Y
- Cobal M
- Coccaro A
- Cochran J
- Codina EP
- Colasurdo L
- Cole B
- Colijn AP
- Collaboration ATLAS
- Collot J
- Colombo T
- Compostella G
- Conde Muino P
- Coniavitis E
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- Connelly IA
- Consorti V
- Constantinescu S
- Conti G
- Conventi F
- Cooke M
- Cooper BD
- Cooper-Sarkar AM
- Cormier KJR
- Cornelissen T
- Corradi M
- Correia AMH
- Corriveau F
- Corso-Radu A
- Cortes-Gonzalez A
- Cortiana G
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- Cox BE
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- Crawley SJ
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- Crescioli F
- Cribbs WA
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- Croft V
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- Cummings J
- Curatolo M
- Cuth J
- Czirr H
- Czodrowski P
- D'amen G
- D'Auria S
- D'Onofrio M
- da Costa JBG
- Da Costa JGPF
- Da Cunha Sargedas De Sous MJ
- Da Via C
- Dabrowski W
- Dado T
- Dai T
- Dale O
- Dallaire F
- Dallapiccola C
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- Damazio DO
- Dandoy JR
- Dang NP
- Daniells AC
- Dann NS
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- Dao V
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- Daya-Ishmukhametova RK
- de Asmundis R
- De Benedetti A
- De Bruin PHS
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- De Groot N
- de Jong P
- De la Torre H
- de Lima DEF
- De Lorenzi F
- De Maria A
- De Mendizabal JB
- De Pedis D
- De Regie JBDV
- de Renstrom PAB
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- De Sanctis U
- De Santo A
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- Dearnaley WJ
- Debbe R
- Debenedetti C
- Dedovich DV
- Dehghanian N
- Deigaard I
- Del Gaudio M
- Del Peso J
- Del Prete T
- Delgove D
- Deliot F
- Delitzsch CM
- Dell'Acqua A
- Dell'Asta L
- Dell'Orso M
- Della Pietra M
- della Volpe D
- Delmastro M
- Delsart PA
- DeMarco DA
- Demers S
- Demichev M
- Demilly A
- Denisov SP
- Denysiuk D
- Derendarz D
- Derkaoui JE
- Derue F
- Dervan P
- Desch K
- Deterre C
- Dette K
- Deviveiros PO
- Dewhurst A
- Dhaliwal S
- Di Ciaccio A
- Di Ciaccio L
- Di Clemente WK
- Di Donato C
- Di Girolamo A
- Di Girolamo B
- Di Micco B
- Di Nardo R
- Di Simone A
- Di Sipio R
- Di Valentino D
- Diaconu C
- Diamond M
- Dias FA
- Diaz MA
- Diehl EB
- Dietrich J
- Diglio S
- Dimitrievska A
- Dingfelder J
- Dita P
- Dita S
- Dittus F
- Djama F
- Djobava T
- Djuvsland JI
- do Vale MAB
- Dobos D
- Dobre M
- Doglioni C
- Dolejsi J
- Dolezal Z
- Donadelli M
- Donati S
- Dondero P
- Donini J
- Donszelmann TC
- Dopke J
- Doria A
- Dova MT
- Doyle AT
- Drechsler E
- Dris M
- Du Y
- Duarte-Campderros J
- Duchovni E
- Duckeck G
- Ducu OA
- Duda D
- Dudarev A
- Dudder AC
- Dueren M
- Duffield EM
- Duflot L
- Duhrssen M
- Dumancic M
- Dunford M
- Durglishvili A
- Duschinger D
- Dutta B
- Dyndal M
- Eckardt C
- Ecker KM
- Edgar RC
- Edwards NC
- Eifert T
- Eigen G
- Einsweiler K
- Ekelof T
- El Kacimi M
- Ellajosyula V
- Ellert M
- Elles S
- Ellinghaus F
- Elliot AA
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- Elmsheuser J
- Elsing M
- Emeliyanov D
- Enari Y
- Endner OC
- Ennis JS
- Erdmann J
- Ereditato A
- Ernis G
- Ernst J
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- Errede S
- Ertel E
- Escalier M
- Esch H
- Escobar C
- Esposito B
- Etienvre AI
- Etzion E
- Evans H
- Ezhilov A
- Fabbri F
- Fabbri L
- Facini G
- Fakhrutdinov RM
- Falciano S
- Falla RJ
- Faltova J
- Fang Y
- Fanti M
- Farbin A
- Farilla A
- Farina C
- Farina EM
- Farooque T
- Farrell S
- Farrington SM
- Farthouat P
- Fassi F
- Fassnacht P
- Fassouliotis D
- Favareto A
- Fawcett WJ
- Fayard L
- Fedin OL
- Fedorko W
- Feigl S
- Feligioni L
- Feng C
- Feng EJ
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- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2015
- Field of study
This Letter presents a measurement of the inelastic proton-proton cross section using 60 μb −1 of pp collisions at a center-of-mass energy √s of 13 TeV with the ATLAS detector at the LHC. Inelastic interactions are selected using rings of plastic scintillators in the forward region (2.0710 −6 , where M X is the larger invariant mass of the two hadronic systems separated by the largest rapidity gap in the event. In this ξ range the scintillators are highly efficient. For diffractive events this corresponds to cases where at least one proton dissociates to a system with M X >13 GeV . The measured cross section is compared with a range of theoretical predictions. When extrapolated to the full phase space, a cross section of 78.1±2.9 mb is measured, consistent with the inelastic cross section increasing with center-of-mass energy
Measurement of the W±Z boson pair-production cross section in pp collisions at √s=13TeV with the ATLAS detector
- Author
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- Aad G
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- Abdallah J
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- Yabsley B
- Yacoob S
- Yakabe R
- Yamaguchi D
- Yamaguchi Y
- Yamamoto A
- Yamamoto S
- Yamanaka T
- Yamauchi K
- Yamazaki Y
- Yan Z
- Yang H
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- Yang Y
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- Yao W-M
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- Yeletskikh I
- Yen AL
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- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJS
- Youssef S
- Yu DR
- Yu J
- Yu J
- Yu JM
- Yuan L
- Yuen SPY
- Yusuff I
- Zabinski B
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- Zaman A
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- Zemla A
- Zeng JC
- Zeng Q
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- Zenin O
- Zenis T
- Zerwas D
- Zhang D
- Zhang F
- Zhang G
- Zhang H
- Zhang J
- Zhang L
- Zhang R
- Zhang R
- Zhang X
- Zhang Z
- Zhao X
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou C
- Zhou L
- Zhou L
- Zhou M
- Zhou N
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann S
- Zinonos Z
- Zinser M
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zu Theenhausen HM
- zur Nedden M
- Zwalinski L
- Publication venue
- Netherlands
- Publication date
- 01/01/2016
- Field of study
published_or_final_versio
Cancer Biomarker Discovery: The Entropic Hallmark
- Author
- A Alcaraz
- A Arabzadeh
- A Bagri
- A Balbin
- A Bantis
- A Ben-Naim
- A Bolander
- A Buhmeida
- A Burykin
- A Chetcuti
- A de Baey
- A Efeyan
- A Eroglu
- A Fabarius
- A Forget
- A Fujita
- A Geirsson
- A Geirsson
- A Geirsson
- A Guffanti
- A Hugel
- A Inoue
- A Isidoro
- A Jang
- A Kollara
- A Kuzmanov
- A Lundqvist
- A Maria McCrohan
- A Marreiros
- A Mendes
- A Mitra
- A Nassar
- A Petitjean
- A Petitjean
- A Pinzon-Charry
- A Richmond
- A Roesch
- A Santinelli
- A Schmidt
- A Shapiro
- A Sreekumar
- A Takeno
- A Urbanucci
- A Winter
- A Yemelyanov
- AA Babiker
- AA Babiker
- AA Tarhini
- AC Dudley
- AD Judge
- AD Ortega
- AG Puebla-Mora
- AH Fox
- AH Fox
- AI Riker
- AJ Liu
- AK Meeker
- AK Panigrahi
- AK Witkiewicz
- AL Cheung
- AL Fachin
- AL Gartel
- AL Okorokov
- AM Craig
- AM Lena
- AM Levin
- AM Tokes
- AP South
- AS Payne
- AS Verkman
- AS Verkman
- AS Verkman
- AS Wierzbicki
- AV Skamrov
- AW Maniccia
- B Cinar
- B Gao
- B Ouyang
- B Ren
- B Ryu
- B Tycko
- B Vukovic
- B Wu
- B Wu
- BD Dimitrov
- BF Gilmore
- BF Goncalves
- BF Skinnider
- BK Zehentner
- BL Adamsen
- BL de Groot
- BR Johnson
- BR Middleman
- BS Strauss
- C Adami
- C Bastide
- C Cao
- C Cybulski
- C Haqq
- C Hayashi
- C Hornig
- C Ivorra
- C Kumar-Sinha
- C Langner
- C Magi-Galluzzi
- C Magi-Galluzzi
- C Muller-Tidow
- C Nessler-Menardi
- C Nunez
- C Pequeux
- C Rajesh
- C Xu
- C Yuli
- CD Sturgis
- CD Truong
- CG Pham
- CG Rogers
- CG Rogers
- CJ Hutchison
- CJ Pronk
- CK Mavis
- CL Stewart
- CL Wu
- CM Caves
- CM Caves
- CM Clemson
- CM Perou
- CP Gray
- CP Gray
- CP Gray
- CR Mangahas
- CS Bond
- D Acehan
- D Bonn
- D Denhardt
- D Fu
- D Gilley
- D Gisselsson
- D Hanahan
- D Javelaud
- D Kroepfl
- D Lodygin
- D Maraldo
- D Ouazia
- D Scadden
- D Wang
- D Wang
- D Wang
- D Weckermann
- D Wodarz
- DA Shoskes
- DA Tennant
- DE Hansel
- DF Gleason
- DG Albertson
- DG Tenen
- DH Palmer
- DJ Darley
- DJ Grignon
- DJ Smit
- DJ Son
- DJ Wong
- DJC MacKay
- DK Koynova
- DK Lee
- DM Kube
- DM Peehl
- DR Wonsey
- DS Perez
- DV Makarov
- DV Makarov
- E Beitz
- E Beitz
- E Cabuy
- E Fagiani
- E Flannery
- E Geissinger
- E Kikuchi
- E Kruse
- E Sbisa
- E Sprecher
- E Tajkhorshid
- EA Ostrander
- EH Feng
- EH Feng
- EM Rosen
- EM Rosen
- EM Schaeffer
- EO Kehinde
- ET Canepa
- EV Vykhovanets
- EY Lin
- EY Tan
- F Bai
- F Bonetto
- F Boralevi
- F Buback
- F Colotta
- F Langer
- F Saad
- F Tas
- F Yang
- FS Krause
- G Benga
- G Bhanot
- G Blandino
- G Buchanan
- G Kaic
- G Kristiansen
- G Kristiansen
- G Kroemer
- G Murugaiyan
- G Petrovics
- G Pirtskhalaishvili
- G Russo
- G Sardana
- G Stirling
- G Tscheudschilsuren
- G Untergasser
- G Venkataraman
- G von Figura
- GA Jarvis
- GE Crooks
- GF Azzone
- GF Ding
- GL Shen-Ong
- GP Bienert
- GQ Daley
- GR Ribeiro
- GS Palapattu
- GV Glinsky
- GV Glinsky
- H Chang-zheng
- H Chen
- H Dzojic
- H Gronberg
- H Haghnegahdar
- H Harant
- H Harlin
- H Kida
- H Li
- H Liu
- H Miyake
- H Nemoto
- H Ostrer
- H Pilch
- H Rangaswami
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- H Ren
- H Roca
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- H Samaratunga
- H Savli
- H Schlechte
- H Schoder
- H Sheng
- H Sunwoo
- H Then
- H Wang
- H Wang
- HC Lee
- HG Thomas
- HJ Worman
- HL Winfield
- HS Leff
- HT Quan
- HY Vu
- HZ Zhang
- I Agalliu
- I Bae
- I Ben-Porath
- I Grosse
- I Haritoglou
- I Leav
- I Marinescu
- I Moll
- I Sakai
- IE Wertz
- IK Lim
- IL Tourkova
- IM Bachmann
- IM Shih
- IW Reiniger
- IY Dodin
- J Bartkova
- J Edwards
- J Fellenberg
- J Gille
- J Graells
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- J Johnson
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- J Lapointe
- J Linden
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- J Wang
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- JD French
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- JD Owen
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- JG Wen
- JH Lee
- JH Luo
- JJ Brey
- JJ Park
- JJ Raffoul
- JJ Tseng
- JJ Van den Oord
- JK Wahl 3rd
- JL Broers
- JL Herrmann
- JL Phillips
- JM Brandner
- JM Bridger
- JM Cummins
- JM Gonzalez
- JM Lizcano
- JM Muller
- JM Muller
- JM Parrondo
- JM Saffin
- JN Hutchinson
- JN Mubiru
- JN Mubiru
- JN Mubiru
- JP Arbitrario
- JP Clark
- JP Ehlers
- JP Fruehauf
- JP Struewing
- JR Cansino Alcaide
- JR McMillan
- JS Butler
- JS Butler
- JS Fang
- JS Hub
- JS Lee
- JS Mattick
- JS Mattick
- JS Mattick
- JT Bishoff
- JT Chang
- JW Denham
- K Armstrong
- K Fujita
- K Ishibashi
- K Ishitani
- K Kami
- K Kasuno
- K Kumagai
- K Mizutani
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- K Ruan
- K Ruan
- K Shilo
- K Sircar
- K Suzuki
- K Swisshelm
- K Takahara
- K Tani
- K Tokunaga
- K Tomkova
- K Trpkov
- K Yamada
- KA Tasken
- KA Zuhlke
- KH Hoffmann
- KH Tsui
- KL Nastiuk
- KL Simpson
- KL van Golen
- KN Ekdahl
- KP Porkka
- KR Ghani
- KV Prasanth
- L Capparuccia
- L Carlsson
- L Cheng
- L de Meis
- L Galluzzi
- L Kneisel
- L Lessard
- L Li
- L Moro
- L Moro
- L O'Regan
- L Packer
- L Pasini
- L True
- L Verdoucq
- L Verschooten
- L Xu
- L Zheng
- LA Diaz-Martinez
- LB Mora
- LE Clarke
- LE Finlan
- LF Brown
- LF Zerbini
- LL Chen
- LL Smith
- LL Smith
- LM Godsel
- LP Kunju
- M Aalamian-Matheis
- M Aghaei
- M Bakhanashvili
- M Boury-Jamot
- M Boury-Jamot
- M Buxade
- M Chellaiah
- M Cimitan
- M Craig
- M Dumas
- M Dundr
- M Esteller
- M Estler
- M Fabbri
- M Fukunaga-Kalabis
- M Fukunaga-Kalabis
- M Furuno
- M Gilbert
- M Hara-Chikuma
- M Hara-Chikuma
- M Hara-Chikuma
- M Hara-Chikuma
- M Hatzfeld
- M Hatzfeld
- M Heenen
- M Ismail
- M Karaivanov
- M Kashani-Sabet
- M Kato
- M Katoh
- M Kinoshita
- M Korabiowska
- M Kulesz-Martin
- M Lei
- M Lisovsky
- M Marko
- M Mellado
- M Mishima
- M Mockenhaupt
- M Moghaddami
- M Moghaddami
- M Nessling
- M Olsson
- M Onaitis
- M Parisi
- M Schostak
- M Tischkowitz
- M Traka
- M Tribus
- M Varma
- M Venoux
- M Watanabe
- M Yang
- M Yasui
- M Zhou
- M Zhou
- M Zhou
- MA Castro
- MA Chekmareva
- MA Chellaiah
- MA Ficazzola
- MA Halsey
- MA Roder
- MA Rubin
- MA Rubin
- MA Rubin
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- MB Rettig
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- MK Thomsen
- MK Thomsen
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- MM Rashid
- MR Rosner
- MS O'Connor
- MS Tretiakova
- MT Kalcioglu
- MT Ling
- MT Martin
- MT Sung
- MV Blagosklonny
- MY Lee
- N Bahamontes-Rosa
- N Donin
- N Konishi
- N Lapteva
- N Maeda
- N Nadiminty
- N Rabiau
- N Singh
- NG Hussein
- NI Andreyev
- NJ Fisch
- NV Whittock
- NV Whittock
- O Bettendorf
- O Canbolat
- O Itzhaki
- O Kwon
- OA Rosso
- OW Rokhlin
- P Agre
- P Agre
- P Agre
- P Agre
- P Allavena
- P Berthon
- P Boukamp
- P Cossu-Rocca
- P Dhawan
- P Dhawan
- P Duesberg
- P Duesberg
- P Duesberg
- P Hainaut
- P Ji
- P Karakiewicz
- P Koivisto
- P Roy-Burman
- P Rustin
- P Sini
- P Slijepcevic
- P Sotomayor
- P Sotomayor
- P Steigemann
- P Zhang
- Pablo Moscato
- PD Walden
- PG Gallagher
- PH Gumerlock
- PH Konig
- PI Nedvetsky
- PJ Gray Jr
- PJ Zielie
- PL Chang
- PM Lacal
- PM Lacal
- PM Mordaka
- PM Steijlen
- PT Landsberg
- PT Went
- PU Malmstrom
- PW Kuchel
- PW Lamberti
- Q Lu
- Q Zhou
- R Agarwal
- R Berretta
- R Birnie
- R Bordoni
- R Casalini
- R Das
- R Dobson
- R Halaban
- R Horuk
- R Klimek
- R Klimek
- R Kuefer
- R Lin
- R Mazzucchelli
- R Mukherjee
- R Radosavljevic
- R Rai
- R Sougrat
- RA Craven
- RA Hegele
- RA Sturm
- RA Weinberg
- RC Lee
- RD Ballal
- RD Loberg
- RD Loberg
- RD Loberg
- RD Loberg
- Regina Berretta
- RG Uzzo
- RJ Jin
- RJ Urban
- RJ Webster
- RL Boguslavsky
- RL Shattuck
- RMH Lopez-Ruiz
- RP Ciavarra
- RP Ciavarra
- RP Singh
- RS Weinstein
- RT Nitta
- RW DeVere White
- S Ashida
- S Brychtova
- S Cardinale
- S Das
- S Das
- S Dettwiler
- S Di Cesare
- S Doratiotto
- S Ersoy-Evans
- S Fan
- S Gagos
- S Ghosh
- S Gunia
- S Hanada
- S Hauptmann
- S Hiratsuka
- S Horsburgh
- S Huerta-Yepez
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- S Jhavar
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- S Kyle
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- S Olgac
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- S Philip
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- S Rankin
- S Rankin
- S Satoh
- S Sur
- S Takahashi
- S Takahashi
- S Tancharoen
- S Verdier-Sevrain
- S Yeh
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- S Zha
- S Zha
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- SH Lin
- SJ Yeung
- SK Kang
- SL Kong
- SL Zheng
- SM Edwards
- SM Ho
- SM Saparov
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- SS Kadkol
- SV Setzer
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- T Drewa
- T Hoevel
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- T Jamaspishvili
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- T Litman
- T Ma
- T Mirtti
- T Murakami
- T Oyama
- T Schlomm
- T Schlomm
- T Sheridan
- T Shimizu
- T Sobolik-Delmaire
- T Sun
- T Takahashi
- T Takeda
- T Thornburg
- T Watanabe
- T Yu
- TB Lewis
- TD Prickett
- TH Ecke
- TJ McDonnell
- TJ Park
- TL Schmit
- TL Schmit
- TO Nielsen
- TR Mercer
- U Brinck
- U Graeven
- U Gruneberg
- UV Wesley
- V Ambros
- V Barak
- V Fradet
- V Molinie
- V Molinie
- V Molinie
- V Molinie
- V Molinie
- V Molinie
- V Pekovic
- V Rajaram
- V Samanna
- V Wessagowit
- V Winnepenninckx
- VD Acevedo
- VK Vanguri
- VL Verstraeten
- W Chen
- W Cosme-Blanco
- W Gade
- W Ritchie
- W Spirkl
- W Tettelbach
- W Wang
- W Weichert
- W Weichert
- W Weichert
- WB Isaacs
- WD Dunsmuir
- WE Naugler
- William C. S. Cho
- WK Kaufmann
- WK Lee
- X Chen
- X Cheng
- X Dong
- X Dong
- X Huang
- X Li
- X Liu
- X Liu
- X Meng
- X Ouyang
- X Tang
- X Wu
- X Zhang
- XJ Yang
- XQ Wang
- Y Bu
- Y Cai
- Y Deng
- Y Ito
- Y Katagiri
- Y Kozuka
- Y Lai
- Y Liu
- Y Lu
- Y Lu
- Y Ohyama
- Y Shav-Tal
- Y Sugiyama
- Y Sun
- Y Wang
- Y Wang
- Y Wu
- Y Yamamoto
- Y Yang
- Y Zhou
- YB Lim
- YC Chao
- YJ Ko
- YL Liu
- YN Liu
- YT Sasaki
- YT Sasaki
- YU Katagiri
- Z Jiang
- Z Jiang
- Z Jiang
- Z Jiang
- Z Jiang
- Z Rudzki
- ZA Dotan
- ZR Yurkovetsky
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2010
- Field of study
Background: It is a commonly accepted belief that cancer cells modify their transcriptional state during the progression of the disease. We propose that the progression of cancer cells towards malignant phenotypes can be efficiently tracked using high-throughput technologies that follow the gradual changes observed in the gene expression profiles by employing Shannon's mathematical theory of communication. Methods based on Information Theory can then quantify the divergence of cancer cells' transcriptional profiles from those of normally appearing cells of the originating tissues. The relevance of the proposed methods can be evaluated using microarray datasets available in the public domain but the method is in principle applicable to other high-throughput methods. Methodology/Principal Findings: Using melanoma and prostate cancer datasets we illustrate how it is possible to employ Shannon Entropy and the Jensen-Shannon divergence to trace the transcriptional changes progression of the disease. We establish how the variations of these two measures correlate with established biomarkers of cancer progression. The Information Theory measures allow us to identify novel biomarkers for both progressive and relatively more sudden transcriptional changes leading to malignant phenotypes. At the same time, the methodology was able to validate a large number of genes and processes that seem to be implicated in the progression of melanoma and prostate cancer. Conclusions/Significance: We thus present a quantitative guiding rule, a new unifying hallmark of cancer: the cancer cell's transcriptome changes lead to measurable observed transitions of Normalized Shannon Entropy values (as measured by high-throughput technologies). At the same time, tumor cells increment their divergence from the normal tissue profile increasing their disorder via creation of states that we might not directly measure. This unifying hallmark allows, via the the Jensen-Shannon divergence, to identify the arrow of time of the processes from the gene expression profiles, and helps to map the phenotypical and molecular hallmarks of specific cancer subtypes. The deep mathematical basis of the approach allows us to suggest that this principle is, hopefully, of general applicability for other diseases
Search for the direct production of charginos and neutralinos in final states with tau leptons in √s=13 TeV collisions with the ATLAS detector
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- Aaboud M
- Aad G
- Abbott B
- Abdinov O
- Abeloos B
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abreu R
- Abulaiti Y
- Acharya BS
- Adachi S
- Adamczyk L
- Adelman J
- Adersberger M
- Adye T
- Affolder AA
- Afik Y
- Agatonovic-Jovin T
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahlen SP
- Ahmadov F
- Aielli G
- Akatsuka S
- Akerstedt H
- Akesson TPA
- Akilli E
- Akimov AV
- Albergh GL
- Albert J
- Albicocco P
- Alconada Verzini MJ
- Alderweireldt SC
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexopoulos T
- Alhroob M
- Ali B
- Aliev M
- Alimonti G
- Alison J
- Alkire SP
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Alshehri AA
- Alstaty MI
- Alvarez Piqueras D
- Alviggi MG
- Amadio BT
- Amelung C
- Amidei D
- Amoroso S
- Amundsen G
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders JK
- Anderson KJ
- Andreazza A
- Andrei V
- Angelidakis S
- Angelozzi I
- Angerami A
- Anisenkov AV
- Anjos N
- Annovi A
- Antel C
- Antonelli M
- Antonov A
- Antrim DJ
- Anulli F
- Aoki M
- Arabidze G
- Arai Y
- Araque JP
- Arce ATH
- Ardell RE
- Arduh FA
- Arguin J-F
- Argyropoulos S
- Arik M
- Armadans R Caminal
- Armbruster AJ
- Armitage LJ
- Arnaez O
- Arnold H
- Arratia M
- Arslan O
- Artamonov A
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- Artz S
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- Astigarraga ME Pozo
- Atkinson M
- Atlay NB
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- Vilucchi E
- Vincter MG
- Vinogradov VB
- Vishwakarma A
- Vittori C
- Vivarelli I
- Vlachos S
- Vogel M
- Vokac P
- Volpi G
- von der Schmitt H
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- Vorobel V
- Vorobev K
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- Wanotayaroj C
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- Webster JS
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- Weingarten J
- Weirich M
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- Weits H
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- Wenaus T
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- Weston TD
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- Winter BT
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- Worm SD
- Wosiek BK
- Wotschack J
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- Yacoob S
- Yamaguchi D
- Yamaguchi Y
- Yamamoto A
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- Yamanaka T
- Yamane F
- Yamatani M
- Yamazaki Y
- Yan Z
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- Yao W-M
- Yap YC
- Yasu Y
- Yatsenko E
- Ye J
- Ye S
- Yeletskikh I
- Yigitbasi E
- Yildirim E
- Yildiz H Duran
- Yorita K
- Yoshihara K
- Young C
- Young CJS
- Yu J
- Yu J
- Yuen SPY
- Yusuff I
- Zabinski B
- Zacharis G
- Zaidan R
- Zaitsev AM
- Zakharchuk N
- Zalieckas J
- Zaman A
- Zambito S
- Zanzi D
- Zeitnitz C
- Zemaityte G
- Zemla A
- Zeng JC
- Zeng Q
- Zenin O
- Zenis T
- Zerwas D
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- Zhang F
- Zhang G
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- Zhang J
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- Zhao X
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- Zhemchugov A
- Zhou B
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- Zhu CG
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- Zhu Y
- Zhuang X
- Zhukov K
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann S
- Zinonos Z
- Zinser M
- Ziolkowski M
- Zivkovic L
- Zobernig G
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- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
A search for the direct production of charginos and neutralinos in final states with at least two hadronically decaying tau leptons is presented. The analysis uses a dataset of pp collisions corresponding to an integrated luminosity of 36.1 fb−1, recorded with the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 13TeV.Nosignificant deviation from the expected Standard Model background is observed. Limits are derived in scenarios of ˜χ+1 ˜χ−1 pair production and of ˜χ±1 ˜χ02 and ˜χ+1 ˜χ−1 production in simplified models where the neutralinos and charginos decay solely via intermediate left-handed staus and tau sneutrinos, and the mass of the ˜ τL state is set to be halfway between the masses of the ˜χ±1 and the ˜χ01. Chargino masses up to 630 GeV are excluded at 95% confidence level in the scenario of direct production of ˜χ+1 ˜χ−1 for a massless ˜χ01. Common ˜χ±1 and ˜χ02 masses up to 760 GeV are excluded in the case of production of ˜χ±1 ˜χ02 and ˜χ+1 ˜χ−1 assuming a massless ˜χ01. Exclusion limits for additional benchmark scenarios with large and small mass-splitting between the ˜χ±1 and the ˜χ01 are also studied by varying the ˜ τL mass between the masses of the ˜χ±1 and the ˜χ01
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