154 research outputs found

    СОВРЕМЕННЫЙ ВЗГЛЯД НА ПРОБЛЕМУ РЕТИНОПАТИИ НЕДОНОШЕННЫХ

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    The article presents a review of the data, which reflects the relevance and modern views on the problem of retinopathy of prematurity, including statistical and epidemiologic data on nosology. Various pathogenetic theories of onset and progression of this disease are discussed. A clear correlation depending on the degree of prematurity, body weight and physical condition of the newborn and the risk of disease is mentioned. The summation of etiology aspects, as well as pathogenesis, classification of clinical forms and the modern approach to the diagnostics is of a quite interest. The article also describes different treatment strategies which include various methods of conservative therapy and surgery, depending on the course and stage of disease. Rehabilitation activities for children who had come through some stage of retinopathy of prematurity and are at risk for the formation of different ophthalmopathology such as refractive errors and pathology of binocular vision in the future and require a subsequent long-term monitoring in the office catamnesis are itemized. The importance of interaction between ophthalmologists and neonatologists at all stages of neonatal screening for providing timely specialized care in order to minimize the occurrence of retinopathy and prevent progression to disabling stages, as well as to improve the quality of life of these patients is shown.В статье представлен обзор данных, отражающих актуальность и современные взгляды на проблему ретинопатии недоношенных, включая статистические и эпидемиологические данные по нозологии заболевания. Рассмотрены различные патогенетические теории возникновения и прогрессирования данной патологии. Указана четкая корреляция в зависимости от степени недоношенности, массы тела, соматического состояния новорожденного и риска возникновения заболевания. Интерес представляет суммирование аспектов этиологии, патогенеза, классификации клинических форм, а также современный подход к диагностике. Также в статье описана тактика лечения, включающая различные методики консервативной терапии и хирургических вмешательств в зависимости от течения и стадии заболевания. Перечислены реабилитационные мероприятия, которые необходимо проводить с учетом того, что дети, перенесшие некоторые стадии ретинопатии недоношенных, входят в группу риска по формированию различной офтальмопатологии, например аномалий рефракции и патологии бинокулярного зрения в будущем, и нуждаются в последующем длительном наблюдении в кабинете катамнеза. Показана важность взаимодействия неонатологов и офтальмологов на всех этапах неонатального скрининга для оказания своевременной специализированной помощи с целью минимизации риска возникновения ретинопатии и предотвращения прогрессирования заболевания до инвалидизирующих стадий, а также улучшения качества жизни данной категории пациентов.

    РЕЗУЛЬТАТЫ ИЗУЧЕНИЯ ИЗОТИПОВ ОБЩИХИММУНОГЛОБУЛИНОВ У БОЛЬНЫХ СИФИЛИСОМ

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    The investigation of the level of common immunoglobulins in 59 patients with Lues and 23 patients with seroresistent Lues revealed some peculiarities that depend on both the clinical form and duration of the infection process as well as the presence of an associated specific affection of the central nervous system. Clinical sings typical for secondary Lues of the skin and mucus membranes are accompanied by intensified synthesis of the proinflammatory isotypes lgМ and IgG3 in the blood. Early hidden Lues is associated with formation of the antiinflammatory IgA isotype. An increased antibody formation is typical for early types of Lues whereas immunoglobulin levels in late types of the disease are normal. In case of a luetic affection of the central nervous system a decreased production of IgM is revealed.Анализ содержания изотипов общих иммуноглобулинов у 59 больных сифилисом и 23 пациентов с наличием серорезистентности выявил особенности, зависящие от клинической формы заболевания и длительности инфекционного процесса, а также ассоциации с развитием специфического поражения ЦНС. Клинические проявления, характерные для вторичного сифилиса кожи и слизистых оболочек, сопровождаются повышенным синтезом в сыворотке крови провоспалительных изотипов lgМ и IgG3, ранний скрытый сифилис - образованием противовоспалительного изотипа IgA. Усиленное антителообразование присуще ранним формам сифилиса, при поздних формах заболевания уровень иммуноглобулинов не отличается от нормальных величин. При сифилитическом поражении нервной системы выявляется сниженная продукция IgM

    Dynamical mean-field approach to materials with strong electronic correlations

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    We review recent results on the properties of materials with correlated electrons obtained within the LDA+DMFT approach, a combination of a conventional band structure approach based on the local density approximation (LDA) and the dynamical mean-field theory (DMFT). The application to four outstanding problems in this field is discussed: (i) we compute the full valence band structure of the charge-transfer insulator NiO by explicitly including the p-d hybridization, (ii) we explain the origin for the simultaneously occuring metal-insulator transition and collapse of the magnetic moment in MnO and Fe2O3, (iii) we describe a novel GGA+DMFT scheme in terms of plane-wave pseudopotentials which allows us to compute the orbital order and cooperative Jahn-Teller distortion in KCuF3 and LaMnO3, and (iv) we provide a general explanation for the appearance of kinks in the effective dispersion of correlated electrons in systems with a pronounced three-peak spectral function without having to resort to the coupling of electrons to bosonic excitations. These results provide a considerable progress in the fully microscopic investigations of correlated electron materials.Comment: 24 pages, 14 figures, final version, submitted to Eur. Phys. J. for publication in the Special Topics volume "Cooperative Phenomena in Solids: Metal-Insulator Transitions and Ordering of Microscopic Degrees of Freedom

    Measurements of differential production cross sections for a Z boson in association with jets in pp collisions at root s=8 TeV

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    Search for leptophobic Z ' bosons decaying into four-lepton final states in proton-proton collisions at root s=8 TeV

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    Search for black holes and other new phenomena in high-multiplicity final states in proton-proton collisions at root s=13 TeV

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    Search for high-mass diphoton resonances in proton-proton collisions at 13 TeV and combination with 8 TeV search

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    Search for heavy resonances decaying into a vector boson and a Higgs boson in final states with charged leptons, neutrinos, and b quarks

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    Search for the associated production of the Higgs boson with a top-quark pair

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    A search for the standard model Higgs boson produced in association with a top-quark pair t t ¯ H (tt¯H) is presented, using data samples corresponding to integrated luminosities of up to 5.1 fb −1 and 19.7 fb −1 collected in pp collisions at center-of-mass energies of 7 TeV and 8 TeV respectively. The search is based on the following signatures of the Higgs boson decay: H → hadrons, H → photons, and H → leptons. The results are characterized by an observed t t ¯ H tt¯H signal strength relative to the standard model cross section, μ = σ/σ SM ,under the assumption that the Higgs boson decays as expected in the standard model. The best fit value is μ = 2.8 ± 1.0 for a Higgs boson mass of 125.6 GeV

    Measurement of prompt Jψ\psi pair production in pp collisions at \sqrt s = 7 Tev

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    Production of prompt J/ ψ meson pairs in proton-proton collisions at s s√ = 7 TeV is measured with the CMS experiment at the LHC in a data sample corresponding to an integrated luminosity of about 4.7 fb −1 . The two J/ ψ mesons are fully reconstructed via their decays into μ + μ − pairs. This observation provides for the first time access to the high-transverse-momentum region of J/ ψ pair production where model predictions are not yet established. The total and differential cross sections are measured in a phase space defined by the individual J/ ψ transverse momentum ( p T J/ ψ ) and rapidity (| y J/ ψ |): | y J/ ψ | 6.5 GeV/ c ; 1.2 4.5 GeV/ c . The total cross section, assuming unpolarized prompt J/ ψ pair production is 1.49 ± 0.07 (stat) ±0.13 (syst) nb. Different assumptions about the J/ ψ polarization imply modifications to the cross section ranging from −31% to +27%
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