Ortodontia baseada no genoma: prognatismo mandibular

Uma das questões centrais da ortodontia moderna é: como as descobertas na área da genética afetarão diretamente conceitos e abordagens no tratamento ortodôntico e de que forma os fatores genómicos e epigenéticos podem ser manipulados e introduzidos no tratamento individual de cada paciente. O objetivo deste trabalho é demonstrar a importância da genética na previsão do crescimento mandibular. Esta dissertação é de índole teórica, estando desta forma isenta de qualquer tipo de trabalho prático experimental. Trata-se de uma revisão sistemática de trabalhos que estudaram o tema. A ortodontia baseada no genoma usa a informação genética para melhorar o diagnóstico e tratamento de distúrbios dentários e deformidades dentofaciais. Nos últimos 20 anos houve uma convergência de princípios e conceitos entre a genética e a ortodontia que levará a um avanço significativo dos tratamentos ortodonticos, contudo a sua aplicação prática não será imediata.The central question in orthodontics in this millennium is: how discoveries in the field of genetics will directly affect concepts and approaches in orthodontic treatment and how genomic and epigenetic factors can be manipulated and introduced into the individual treatment of each patient. The aim of this study is to demonstrate the importance of genetics in the prediction of mandibular growth. This dissertation is of a theoretical nature, being thus exempt of any type of practical experimental work. This is a systematic review of papers that have studied the theme. Genome based orthodontics uses genetic information to improve the diagnosis and treatment of dental disorders and dentofacial deformities. In the last 20 years there has been a convergence of principles and concepts between genetics and orthodontics that will lead to a significant advance in orthodontic treatments, however, its practical application will not be immediate

Ortodontia baseada no genoma: prognatismo mandibular

Uma das questões centrais da ortodontia moderna é: como as descobertas na área da genética afetarão diretamente conceitos e abordagens no tratamento ortodôntico e de que forma os fatores genómicos e epigenéticos podem ser manipulados e introduzidos no tratamento individual de cada paciente. O objetivo deste trabalho é demonstrar a importância da genética na previsão do crescimento mandibular. Esta dissertação é de índole teórica, estando desta forma isenta de qualquer tipo de trabalho prático experimental. Trata-se de uma revisão sistemática de trabalhos que estudaram o tema. A ortodontia baseada no genoma usa a informação genética para melhorar o diagnóstico e tratamento de distúrbios dentários e deformidades dentofaciais. Nos últimos 20 anos houve uma convergência de princípios e conceitos entre a genética e a ortodontia que levará a um avanço significativo dos tratamentos ortodonticos, contudo a sua aplicação prática não será imediata.The central question in orthodontics in this millennium is: how discoveries in the field of genetics will directly affect concepts and approaches in orthodontic treatment and how genomic and epigenetic factors can be manipulated and introduced into the individual treatment of each patient. The aim of this study is to demonstrate the importance of genetics in the prediction of mandibular growth. This dissertation is of a theoretical nature, being thus exempt of any type of practical experimental work. This is a systematic review of papers that have studied the theme. Genome based orthodontics uses genetic information to improve the diagnosis and treatment of dental disorders and dentofacial deformities. In the last 20 years there has been a convergence of principles and concepts between genetics and orthodontics that will lead to a significant advance in orthodontic treatments, however, its practical application will not be immediate

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Anthropology in Portugal

Portuguese anthropology had its beginnings with the work of late nineteenth‐century folklorists, ethnographers, linguists, archaeologists, and physical anthropologists, in tune with international debates and in parallel with their European counterparts. In the twentieth century, physical anthropology had modest yet uninterrupted development whereas the social and cultural components of the discipline had a fragmented history, mostly for political reasons. There were ethnographic works conducted in Portugal and its colonies but researchers could not expand the analysis into some of the social issues and political contexts directly related to the subject of study. After the end of the authoritarian regime in 1974, social and cultural anthropology made up for lost time and dozens of works on Portugal were conducted in the 1980s and beyond. By the end of the twentieth century, the field was vibrant, diverse, and international, with hundreds of graduates and a large number of research projects, books, and journals.info:eu-repo/semantics/publishedVersio

Estácio de Sá e a fundação do Rio de Janeiro Estácio de Sa and the founding of Rio de Janeiro

O artigo aborda a presença de Estácio de Sá no Rio de Janeiro, bem como a sua fundação e a expulsão dos franceses, que chegaram aqui sob o comando de Villegagnon, em 1555, formando a França Antártica. Discute a participação da armada de Estácio de Sá na guerra contra os tamoios e tupiniquins em São Vicente, a fim de conseguir recursos humanos e mantimentos para retornar à luta na Guanabara. Por fim, questiona se Estácio de Sá teria sido governador ou somente capitão da cidade de São Sebastião do Rio de Janeiro.<br>The article deals with Estacio de Sa's presence in Rio de Janeiro as well as its foundation and the expulsion of the French that arrived here under the command of Villegagnon in 1555 having established the French Antarctic. It argues the participation of the Estacio de Sa armada in the war against the tamoios and tupiniquins in Sao Vicente, which had the purpose of obtaining human resources and supplies to return to the struggle in Guanabara. In the end, it questions as to whether Estacio de Sa had been governor or only captain of the city of Sao Sebastiao in Rio de Janeiro