Estudio descriptivo de las cavidades pleurales residuales complicadas tratadas en un Servicio de Cirugía Torácica

Introducción: Las cavidades pleurales residuales se definen como espacios pleurales causados por una falta de reexpansión pulmonar principalmente secundario a infecciones pleurales o cirugías torácicas. Estas pueden cronificarse y complicarse si no logran resolverse con los tratamientos de primera línea (drenaje torácico, fibrinolíticos o decorticación quirúrgica). Material y Métodos: Estudio descriptivo retrospectivo de los pacientes con cavidades pleurales residuales complicadas (CPRC) en el Servicio de Cirugía Torácica del Complejo Hospitalario Universitario de Albacete desde noviembre del 2004 hasta mayo del 2015. Resultados: Sesenta y tres pacientes fueron diagnosticados, con una mayor frecuencia en hombres (n=57; 90,5%). Del total de pacientes intervenidos en este periodo, el 16,27% de cirugías fueron secundarias a esta patología. La patología infecciosa fue la más frecuente (n=35; 55,6%) y dentro de la post-quirúrgica la neumonectomía (n=8; 42,1%), con una media de días desde la intervención quirúrgica hasta el diagnóstico de 190,7 días. En 43 pacientes (68,3%) el cultivo del líquido pleural fue positivo. En 17 pacientes (27%) se asoció a una fístula broncopleural. De los 63 pacientes, 16 (25,4%) recibieron un único tratamiento quirúrgico (25,4%), mientras que 47 (74,6%), precisaron más de un tratamiento. En 39 casos (61,9%) la cavidad pleural complicada se resolvió por medio de los tratamientos, mientras que no lo hizo en 24 (38,1%) pacientes. Conclusiones: A pesar de ser una patología poco frecuente continua presente en la actualidad, principalmente como complicación postquirúrgica o infecciosa. Los tratamientos descritos hasta la fecha no revelan una alta eficacia.Introduction: Residual pleural cavities are pleural spaces caused by a lack of pulmonary reexpansion mainly secondary to pleural infections or thoracic surgeries. If they can not be solved with first line treatments (thoracic drainage, fibrinolytics or surgical decortication), these can become cronic and complicate. Material and Methods: Retrospective descriptive study of patients with complicated residual pleural cavities at the Thoracic Surgery Service of the “Complejo Hospitalario Universitario de Albacete” from November 2004 to May 2015. Results: Sixty-three patients were diagnosed, showing that incidence was more frequent in men (n=57; 90.5%). 16.27% of the surgeries treated within this period were secondary to this pathology. The infectious pathology was the most frequent (n = 35; 55.6%), whereas within the postoperative group, it was pneumonectomy (n = 8; 42.1%), with 190.7 days in average from surgical intervention to the diagnosis. In 43 patients (68.3%), the pleural fluid culture was positive. In 17 patients (27%), it was associated with a bronchopleural fistula. From the 63 patients, 16 (25.4%) received a single surgical treatment (25.4%), while 47 (74.6%) required more than one treatment. In 39 cases (61.9%), the complicated pleural cavity was resolved, whereas in 24 (38.1%) patients it wasn’t. Conclusions: Despite it being a rare pathology, it is still present today, mainly as a post-surgical or infectious complication. To date, the treatments described haven’t exhibited high efficacy

Optimizing the DFCN Broadcast Protocol with a Parallel Cooperative Strategy of Multi-Objective Evolutionary Algorithms

Proceeding of: 5th International Conference, EMO 2009, Nantes, France, April 7-10, 2009This work presents the application of a parallel coopera- tive optimization approach to the broadcast operation in mobile ad-hoc networks (manets). The optimization of the broadcast operation im- plies satisfying several objectives simultaneously, so a multi-objective approach has been designed. The optimization lies on searching the best configurations of the dfcn broadcast protocol for a given manet sce- nario. The cooperation of a team of multi-objective evolutionary al- gorithms has been performed with a novel optimization model. Such model is a hybrid parallel algorithm that combines a parallel island- based scheme with a hyperheuristic approach. Results achieved by the algorithms in different stages of the search process are analyzed in order to grant more computational resources to the most suitable algorithms. The obtained results for a manets scenario, representing a mall, demon- strate the validity of the new proposed approach.This work has been supported by the ec (feder) and the Spanish Ministry of Education and Science inside the ‘Plan Nacional de i+d+i’ (tin2005-08818-c04) and (tin2008-06491-c04-02). The work of Gara Miranda has been developed under grant fpu-ap2004-2290.Publicad

Centrality dependence of charged particle production at large transverse momentum in Pb-Pb collisions at sNN=2.76\sqrt{s_{\rm{NN}}} = 2.76 TeV

The inclusive transverse momentum ($p_{\rm T}$) distributions of primary charged particles are measured in the pseudo-rapidity range $|\eta|<0.8$ as a function of event centrality in Pb-Pb collisions at $\sqrt{s_{\rm{NN}}}=2.76$ TeV with ALICE at the LHC. The data are presented in the $p_{\rm T}$ range $0.15<p_{\rm T}<50$ GeV/$c$ for nine centrality intervals from 70-80% to 0-5%. The Pb-Pb spectra are presented in terms of the nuclear modification factor $R_{\rm{AA}}$ using a pp reference spectrum measured at the same collision energy. We observe that the suppression of high-$p_{\rm T}$ particles strongly depends on event centrality. In central collisions (0-5%) the yield is most suppressed with $R_{\rm{AA}}\approx0.13$ at $p_{\rm T}=6$-7 GeV/$c$. Above $p_{\rm T}=7$ GeV/$c$, there is a significant rise in the nuclear modification factor, which reaches $R_{\rm{AA}} \approx0.4$ for $p_{\rm T}>30$ GeV/$c$. In peripheral collisions (70-80%), the suppression is weaker with $R_{\rm{AA}} \approx 0.7$ almost independently of $p_{\rm T}$. The measured nuclear modification factors are compared to other measurements and model calculations.Comment: 17 pages, 4 captioned figures, 2 tables, authors from page 12, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/284

Anthropogenic activities in the páramo trigger ecological shifts in Tropical Andean lakes

A robust understanding of the impact of anthropogenic activities on high-altitude tropical aquatic ecosystems is key for the conservation and protection of the Tropical Andean biodiversity hot spot. We present the results of a multiproxy study of lake sediments from the high Andean páramo of El Cajas National Park, a UNESCO biosphere reserve in Ecuador. The main site, Laguna Pallcacocha, is well known for recording El Niño-driven clastic flood layers that are triggered by high-intensity rainfall anomalies from the eastern Pacific. The second site, Laguna El Ocho, does not contain clastic laminations, providing a control. The records show abrupt shifts in diatom assemblages ca. AD 1991 in both high-elevation Andean lakes accompanied by local changes in páramo composition that suggest a sudden nutrient enrichment of the environment. The diatom assemblages from Laguna Pallcacocha, in relation to the clastic input events, are remarkably stable and do not show evident El Niño signals at the analysed resolution. Based on comparison with the nonlaminated El Ocho record, we deduce the main source of this nutrient enrichment to be the construction of a heavily transited road that runs through the park, while climate warming played secondary role by amplifying its effects

Multilocal programming and applications

Preprint versionMultilocal programming aims to identify all local minimizers of unconstrained or constrained nonlinear optimization problems. The multilocal programming theory relies on global optimization strategies combined with simple ideas that are inspired in deflection or stretching techniques to avoid convergence to the already detected local minimizers. The most used methods to solve this type of problems are based on stochastic procedures and a population of solutions. In general, population-based methods are computationally expensive but rather reliable in identifying all local solutions. In this chapter, a review on recent techniques for multilocal programming is presented. Some real-world multilocal programming problems based on chemical engineering process design applications are described.Fundação para a Ciência e a Tecnologia (FCT

Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at sNN=2.76\sqrt{s_{\rm NN}}=2.76 TeV

The elliptic, $v_2$, triangular, $v_3$, and quadrangular, $v_4$, azimuthal anisotropic flow coefficients are measured for unidentified charged particles, pions and (anti-)protons in Pb-Pb collisions at $\sqrt{s_{\rm NN}} = 2.76$ TeV with the ALICE detector at the Large Hadron Collider. Results obtained with the event plane and four-particle cumulant methods are reported for the pseudo-rapidity range $|\eta|<0.8$ at different collision centralities and as a function of transverse momentum, $p_{\rm T}$, out to $p_{\rm T}=20$ GeV/$c$. The observed non-zero elliptic and triangular flow depends only weakly on transverse momentum for $p_{\rm T}>8$ GeV/$c$. The small $p_{\rm T}$ dependence of the difference between elliptic flow results obtained from the event plane and four-particle cumulant methods suggests a common origin of flow fluctuations up to $p_{\rm T}=8$ GeV/$c$. The magnitude of the (anti-)proton elliptic and triangular flow is larger than that of pions out to at least $p_{\rm T}=8$ GeV/$c$ indicating that the particle type dependence persists out to high $p_{\rm T}$.Comment: 16 pages, 5 captioned figures, authors from page 11, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/186

Measurement of charm production at central rapidity in proton-proton collisions at s=2.76\sqrt{s} = 2.76 TeV

The $p_{\rm T}$-differential production cross sections of the prompt (B feed-down subtracted) charmed mesons D$^0$, D$^+$, and D$^{*+}$ in the rapidity range $|y|<0.5$, and for transverse momentum $1< p_{\rm T} <12$ GeV/$c$, were measured in proton-proton collisions at $\sqrt{s} = 2.76$ TeV with the ALICE detector at the Large Hadron Collider. The analysis exploited the hadronic decays D$^0 \rightarrow$K$\pi$, D$^+ \rightarrow$K$\pi\pi$, D$^{*+} \rightarrow$D$^0\pi$, and their charge conjugates, and was performed on a $L_{\rm int} = 1.1$ nb$^{-1}$ event sample collected in 2011 with a minimum-bias trigger. The total charm production cross section at $\sqrt{s} = 2.76$ TeV and at 7 TeV was evaluated by extrapolating to the full phase space the $p_{\rm T}$-differential production cross sections at $\sqrt{s} = 2.76$ TeV and our previous measurements at $\sqrt{s} = 7$ TeV. The results were compared to existing measurements and to perturbative-QCD calculations. The fraction of cdbar D mesons produced in a vector state was also determined.Comment: 20 pages, 5 captioned figures, 4 tables, authors from page 15, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/307

Consenso colombiano de atención, diagnóstico y manejo de la infección por SARS-COV-2/COVID-19 en establecimientos de atención de la salud Recomendaciones basadas en consenso de expertos e informadas en la evidencia

The “Asociación Colombiana de Infectología” (ACIN) and the “Instituto de Evaluación de Nuevas Tecnologías de la Salud” (IETS) created a task force to develop recommendations for Covid 19 health care diagnosis, management and treatment informed, and based, on evidence. Theses reccomendations are addressed to the health personnel on the Colombian context of health services. © 2020 Asociacion Colombiana de Infectologia. All rights reserved