When Task Conflict Becomes Personal: The Impact of Perceived Team Performance

Although potentially beneficial, task conflict may threaten teams because it often leads to relationship conflict. Prior research has identified a set of interpersonal factors (e.g., team communication, team trust) that help attenuate this association. The purpose of this article is to provide an alternative perspective that focuses on the moderating role of performance-related factors (i.e., perceived team performance). Using social identity theory, we build a model that predicts how task conflict associates with growth in relationship conflict and how perceived team performance influences this association. We test a three-wave longitudinal model by means of random coefficient growth modeling, using data from 60 ongoing teams working in a health care organization. Results provide partial support for our hypotheses. Only when perceived team performance is low, do task conflicts relate with growth in relationship conflict. We conclude that perceived team performance seems to enable teams to uncouple task from relationship conflict

Minimal information for studies of extracellular vesicles 2018 (MISEV2018):a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structures, called exosomes, microvesicles, microparticles, ectosomes, oncosomes, apoptotic bodies, and many other names. However, specific issues arise when working with these entities, whose size and amount often make them difficult to obtain as relatively pure preparations, and to characterize properly. The International Society for Extracellular Vesicles (ISEV) proposed Minimal Information for Studies of Extracellular Vesicles (“MISEV”) guidelines for the field in 2014. We now update these “MISEV2014” guidelines based on evolution of the collective knowledge in the last four years. An important point to consider is that ascribing a specific function to EVs in general, or to subtypes of EVs, requires reporting of specific information beyond mere description of function in a crude, potentially contaminated, and heterogeneous preparation. For example, claims that exosomes are endowed with exquisite and specific activities remain difficult to support experimentally, given our still limited knowledge of their specific molecular machineries of biogenesis and release, as compared with other biophysically similar EVs. The MISEV2018 guidelines include tables and outlines of suggested protocols and steps to follow to document specific EV-associated functional activities. Finally, a checklist is provided with summaries of key points

Reduced rate of cutaneous squamous cell carcinoma in a randomised, prospective, multi-centre controlled trial of conversion to sirolimus-based immunosuppression: The RESCUE Trial

Hop Bicetre, Dept Nephrol & Transplantat, Le Kremlin Bicetre, FranceUniv Hosp Bellvitge, Dept Nephrol, Barcelona, SpainHosp Rim & Hipertensao Unifesp, Div Nephrol, Sao Paulo, BrazilUniv Hosp Leuven, Dept Nephrol, Louvain, BelgiumUCSF Kidney Transplant Serv, Div Nephrol, San Francisco, CA USABristol Myers Squibb Co, Global Biometr Sci, Hopewell, NJ USABristol Myers Squibb Co, Global Clin Res, Princeton, NJ USAEmory Univ, Transplant Ctr, Atlanta, GA 30322 USAHosp Rim & Hipertensao Unifesp, Div Nephrol, Sao Paulo, BrazilWeb of Scienc