288 research outputs found
Fluoxetine: a case history of its discovery and preclinical development
- Author
- Publication venue
- 'Informa Healthcare'
- Publication date
- 01/01/2014
- Field of study
Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS. Advances in drug discovery have widened the therapeutic options with the synthesis of so-called selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine.
Areas covered: The aim of this case history is to describe and discuss the pharmacokinetic and pharmacodynamic profiles of fluoxetine, including its acute effects and the adaptive changes induced after long-term treatment.
Furthermore, the authors review the effect of fluoxetine on neuroplasticity and adult neurogenesis. In addition, the article summarises the preclinical behavioural data available on fluoxetineâs effects on depressive-like behaviour,
anxiety and cognition as well as its effects on other diseases. Finally, the article describes the seminal studies validating the antidepressant effects of fluoxetine.
Expert opinion: Fluoxetine is the first selective SSRI that has a recognised clinical efficacy and safety profile. Since its discovery, other molecules that mimic its mechanism of action have been developed, commencing a new
age in the treatment of depression. Fluoxetine has also demonstrated utility in the treatment of other disorders for which its prescription has now been approved
Allorecognition in the Tasmanian Devil (Sarcophilus harrisii), an Endangered Marsupial Species with Limited Genetic Diversity
- Author
- A Castro-Prieto
- A Fassati
- A Kreiss
- A Kreiss
- A Kreiss
- A Kumanovics
- AH Sarris
- AL Ackerman
- Alexandre Kreiss
- AM Pearse
- B Rinkevich
- B Vokaer
- Barrie Wells
- BE Shaw
- C Lehmann
- C Tovar
- CD Richters
- CE Hawkins
- D Cohen
- D Cohen
- DS Game
- DS Game
- DS Stoner
- EP Murchison
- F Nishigaki
- Frank Kimble
- GM Woods
- Gregory M. Woods
- H Ikeda
- H Krichen
- H McCallum
- HD Chen
- HV Siddle
- HV Siddle
- HV Siddle
- J Kanitakis
- J Klein
- J Pascual Santos
- JD Thompson
- JH Adler
- K Belov
- Katherine Belov
- KH Lee
- L Munson
- L Rivoltini
- LA Sherman
- M Berlanda
- M Jeras
- Matthias G. von Herrath
- ME Jones
- MJ Maeurer
- MP Hernandez-Fuentes
- N Sasaki
- PB Medawar
- PE Jensen
- PS Cho
- R Ashbel
- R Loh
- R Loh
- RA Derks
- S Ferrone
- Shaun Donovan
- SJ O'Brien
- SS Wachtel
- T Hall
- Yuanyuan Cheng
- YW Hsiao
- YW Hsiao
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
Tasmanian devils (Sarcophilus harrisii) are on the verge of extinction due to a transmissible cancer, devil facial tumour disease (DFTD). This tumour is an allograft that is transmitted between individuals without immune recognition of the tumour cells. The mechanism to explain this lack of immune recognition and acceptance is not well understood. It has been hypothesized that lack of genetic diversity at the Major Histocompatibility Complex (MHC) allowed the tumour cells to grow in genetically similar hosts without evoking an immune response to alloantigens. We conducted mixed lymphocyte reactions and skin grafts to measure functional MHC diversity in the Tasmanian devil population. The limited MHC diversity was sufficient to produce measurable mixed lymphocyte reactions. There was a wide range of responses, from low or no reaction to relatively strong responses. The highest responses occurred when lymphocytes from devils from the east of Tasmania were mixed with lymphocytes from devils from the west of Tasmania. All of the five successful skin allografts were rejected within 14 days after surgery, even though little or no MHC I and II mismatches were found. Extensive T-cell infiltration characterised the immune rejection. We conclude that Tasmanian devils are capable of allogeneic rejection. Consequently, a lack of functional allorecognition mechanisms in the devil population does not explain the transmission of a contagious cancer
Characteristic Evolution and Matching
- Author
- A Bayliss
- A Nagar
- A Nayfeh
- AM Abrahams
- AM Abrahams
- AM Abrahams
- AM Abrahams
- B Engquist
- B Gustafsson
- B Gustafsson
- B SzilĂĄgyi
- B SzilĂĄgyi
- B SzilĂĄgyi
- BC Xanthopoulos
- C Gundlach
- C Gundlach
- C Gundlach
- C Reisswig
- C Ronchi
- CJS Clarke
- CJS Clarke
- CO Lousto
- D Christodoulou
- D Christodoulou
- D Christodoulou
- D Christodoulou
- D Christodoulou
- D Christodoulou
- D Christodoulou
- D Garfinkle
- D Garfinkle
- D Givoli
- D Pollney
- DS Butler
- DS Goldwirth
- E Gallo
- E Poisson
- E Seidel
- E Sorkin
- EL Lindman
- ET Newman
- ET Newman
- ET Newman
- F Linke
- F Pretorius
- F Pretorius
- F Pretorius
- F Siebel
- F Siebel
- F Siebel
- F Siebel
- FJ Zerilli
- G Calabrese
- G Calabrese
- GA Sod
- GB Cook
- GFD Duff
- GL Browning
- GW Hedstrom
- H Bondi
- H Bondi
- H Friedrich
- H Friedrich
- H Friedrich
- H Friedrich
- H Friedrich
- H Friedrich
- H Jiang
- H MĂŒller Zum Hagen
- H-O Kreiss
- H-O Kreiss
- H-O Kreiss
- H-O Kreiss
- J Baker
- J BiÄĂĄk
- J Moerloose de
- J Thornburg
- J Thornburg
- J Weber
- J Winicour
- J Winicour
- J Winicour
- J Winicour
- JC Miller
- JG Baker
- JG Baker
- JG Blaschak
- JL Anderson
- JL Anderson
- JL Anderson
- JL Anderson
- JL Anderson
- JL Friedman
- JM Stewart
- JM Stewart
- JM Stewart
- JM Stewart
- JM Stewart
- JR Ipser
- JW York Jr
- KA Khan
- KRP Sjödin
- KW Thompson
- L Derry
- L Lehner
- L Lehner
- L Lehner
- L Lehner
- L Rezzolla
- L Ting
- LA Tamburino
- LM Burko
- LM Burko
- LN Trefethen
- M Alcubierre
- M Babiuc
- M Campanelli
- M Campanelli
- M Israeli
- M Ruiz
- M Shibata
- MA Scheel
- MA Scheel
- MC Babiuc
- MC Babiuc
- ME Rupright
- MJ Grote
- ML Gnedin
- MM May
- MR Dubal
- MW Choptuik
- MW Choptuik
- NA Phillips
- NT Bishop
- NT Bishop
- NT Bishop
- NT Bishop
- NT Bishop
- NT Bishop
- NT Bishop
- NT Bishop
- NT Bishop
- NT Bishop
- NT Bishop
- NT Bishop
- NT Bishop
- O Rinne
- O Sarbach
- P Anninos
- P BizoĆ
- P Papadopoulos
- P Papadopoulos
- P Papadopoulos
- PO Papadopoulos
- PR Brady
- PR Brady
- PR Brady
- R Arnowitt
- R Bartnik
- R Bartnik
- R Bartnik
- R Bartnik
- R Bartnik
- R Bartnik
- R Bartnik
- R Geroch
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R GĂłmez
- R Penrose
- R Penrose
- RA dâInverno
- RA dâInverno
- RA dâInverno
- RA Isaacson
- RA Matzner
- RA Renaut
- RD Sorkin
- RE Kates
- RF Stark
- RH Price
- RH Price
- RK Sachs
- RK Sachs
- RK Sachs
- RL Higdon
- RL Marsa
- RM Wald
- RS Hamadé
- RS Hamadé
- RW Corkill
- S Frittelli
- S Frittelli
- S Frittelli
- S Hod
- S Hod
- S Hod
- S Hod
- S Hod
- S Hod
- S Hod
- S Hod
- S Hod
- S Husa
- S Husa
- S Husa
- S Husa
- SA Hayward
- SA Teukolsky
- SA Teukolsky
- SJ Fletcher
- SL Shapiro
- SV Tsynkov
- T Hagstrom
- T Piran
- T Piran
- T Piran
- T Regge
- TW Baumgarte
- TW Baumgarte
- TW Baumgarte
- U Sperhake
- V Moncrief
- V Ryabenâkii
- W Barreto
- W Barreto
- W Barreto
- W Barreto
- W Barreto
- WL Burke
- Y Oren
- Y Zlochower
- Y Zlochower
- Publication venue
- 'Living Reviews'
- Publication date
- 01/01/1998
- Field of study
I review the development of numerical evolution codes for general relativity
based upon the characteristic initial value problem. Progress in characteristic
evolution is traced from the early stage of 1D feasibility studies to 2D
axisymmetric codes that accurately simulate the oscillations and gravitational
collapse of relativistic stars and to current 3D codes that provide pieces of a
binary black hole spacetime. Cauchy codes have now been successful at
simulating all aspects of the binary black hole problem inside an artificially
constructed outer boundary. A prime application of characteristic evolution is
to extend such simulations to null infinity where the waveform from the binary
inspiral and merger can be unambiguously computed. This has now been
accomplished by Cauchy-characteristic extraction, where data for the
characteristic evolution is supplied by Cauchy data on an extraction worldtube
inside the artificial outer boundary. The ultimate application of
characteristic evolution is to eliminate the role of this outer boundary by
constructing a global solution via Cauchy-characteristic matching. Progress in
this direction is discussed.Comment: New version to appear in Living Reviews 2012. arXiv admin note:
updated version of arXiv:gr-qc/050809
Declining Rates in Male Circumcision amidst Increasing Evidence of its Public Health Benefit
- Author
- AE Grulich
- AJ Fink
- B Auvert
- Charlotte K. Kent
- DM Fergusson
- DS Kim
- E Vittinghoff
- EJ Schoen
- EJ Schoen
- EO Laumann
- HA Weiss
- HJ Stang
- Jeffrey D. Klausner
- JG Kahn
- JK Kreiss
- Keymanthri Moodley
- M Fayre Milos
- M Urassa
- MJ Wawer
- R Szabo
- RC Bailey
- RC Bailey
- RH Gray
- Robert P. Kohn
- RS Van Howe
- RS Van Howe
- S Moses
- SP Buchbinder
- T Langeni
- Zohar Mor
- Publication venue
- Public Library of Science
- Publication date
- 12/09/2007
- Field of study
BACKGROUND: Recent experimental evidence has demonstrated the benefits of male circumcision for the prevention of human immunodeficiency virus (HIV) infection. Studies have also shown that male circumcision is cost-effective and reduces the risk for certain ulcerative sexually transmitted diseases (STDs). The epidemiology of male circumcision in the United States is poorly studied and most prior reports were limited by self-reported measures. The study objective was to describe male circumcision trends among men attending the San Francisco municipal STD clinic, and to correlate the findings with HIV, syphilis and sexual orientation. METHODS AND FINDINGS: A cross sectional study was performed by reviewing all electronic records of males attending the San Francisco municipal STD clinic between 1996 and 2005. The prevalence of circumcision over time and by subpopulation such as race/ethnicity and sexual orientation were measured. The findings were further correlated with the presence of syphilis and HIV infection. Circumcision status was determined by physical examination and disease status by clinical evaluation with laboratory confirmation. Among 58,598 male patients, 32,613 (55.7%, 95% Confidence Interval (CI) 55.2-56.1) were circumcised. Male circumcision varied significantly by decade of birth (increasing between 1920 and 1950 and declining overall since the 1960's), race/ethnicity (Black: 62.2%, 95% CI 61.2-63.2, White: 60.0%, 95% CI 59.46-60.5, Asian Pacific Islander: 48.2%, 46.9-49.5 95% CI, and Hispanic: 42.2%, 95% CI 41.3-43.1), and sexual orientation (gay/bisexual: 73.0%, 95% CI 72.6-73.4; heterosexual: 66.0%, 65.5-66.5). Male circumcision may have been modestly protective against syphilis in HIV-uninfected heterosexual men (PR 0.92, 95% C.I. 0.83-1.02, P = 0.06). CONCLUSIONS: Male circumcision was common among men seeking STD services in San Francisco but has declined substantially in recent decades. Male circumcision rates differed by race/ethnicity and sexual orientation. Given recent studies suggesting the public health benefits of male circumcision, a reconsideration of national male circumcision policy is needed to respond to current trends
Sry delivery to the adrenal medulla increases blood pressure and adrenal medullary tyrosine hydroxylase of normotensive WKY rats
- Author
- A Caplea
- A Milsted
- Amy Milsted
- B Folkow
- D Ely
- D Ely
- D Hooper
- D Wiley
- Daniel Ely
- DL Ely
- DL Ely
- DL Ely
- DS Goldstein
- E Andrews
- E Moura
- G Lahr
- G Mancia
- G Rizzuto
- G Rizzuto
- G Rizzuto
- Gail Dunphy
- Jason Bertram
- JH Rahn
- JP Rapp
- K Yoshizato
- M Tsujie
- Mat Ciotti
- Monte E Turner
- MW Nachman
- P Koopman
- P Kreiss
- S Julius
- S Schinner
- S Valigora
- T Kumai
- T Kumai
- T Kumai
- T Nagatsu
- U Sharma
- VL Snyder
- Publication venue
- BioMed Central
- Publication date
- 01/01/2007
- Field of study
BACKGROUND: Our laboratory has shown that a locus on the SHR Y chromosome increases blood pressure (BP) in the SHR rat and in WKY rats that had the SHR Y chromosome locus crossed into their genome (SHR/y rat). A potential candidate for this Y chromosome hypertension locus is Sry, a gene that encodes a transcription factor that is responsible for testes development and the Sry protein may affect other target genes. METHODS: The following study examined if exogenous Sry would elevate adrenal Th, adrenal catecholamines, plasma catecholamines and blood pressure. We delivered 10 ÎŒg of either the expression construct, Sry1/pcDNA 3.1, or control vector into the adrenal medulla of WKY rats by electroporation. Blood pressure was measured by the tail cuff technique and Th and catecholamines by HPLC with electrochemical detection. RESULTS: In the animals receiving Sry there were significant increases after 3 weeks in resting plasma NE (57%) and adrenal Th content (49%) compared to vector controls. BP was 30 mmHg higher in Sry injected animals (160 mmHg, p < .05) compared to vector controls (130 mmHg) after 2â3 weeks. Histological analysis showed that the electroporation procedure did not produce morphological damage. CONCLUSION: These results provide continued support that Sry is a candidate gene for hypertension. Also, these results are consistent with a role for Sry in increasing BP by directly or indirectly activating sympathetic nervous system activity
Observation of associated near-side and away-side long-range correlations in âsNN=5.02ââTeV proton-lead collisions with the ATLAS detector
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdel Khalek S
- Abdelalim AA
- Abdinov O
- Aben R
- Abi B
- Abolins M
- Abouzeid OS
- Abramowicz H
- Abreu H
- Acharya BS
- Adamczyk L
- Adams DL
- Addy TN
- Adelman J
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Agustoni M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akesson TP
- Akimoto G
- Akimov AV
- Alam MA
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Allbrooke BM
- Allison LJ
- Allport PP
- Allwood-Spiers SE
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso F
- Altheimer A
- Alvarez Gonzalez B
- Alviggi MG
- Amako K
- Amelung C
- Ammosov VV
- Amor Dos Santos SP
- Amorim A
- Amoroso S
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Anduaga XS
- Angelidakis S
- Anger P
- Angerami A
- Anghinolfi F
- Anisenkov A
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoki M
- Aperio Bella L
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Arce AT
- Arfaoui S
- Arguin JF
- Argyropoulos S
- Arik E
- Arik M
- Armbruster AJ
- Arnaez O
- Arnal V
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Ask S
- Asman B
- Asquith L
- Assamagan K
- Astalos R
- Astbury A
- Atkinson M
- ATLAS Collaboration The
- Auerbach B
- Auge E
- Augsten K
- Aurousseau M
- Avolio G
- Axen D
- Azuelos G
- Azuma Y
- Baak MA
- Baccaglioni G
- Bacci C
- Bach AM
- Bachacou H
- Bachas K
- Backes M
- Backhaus M
- Backus Mayes J
- Badescu E
- Bagnaia P
- Bai Y
- Bailey DC
- Bain T
- Baines JT
- Baker OK
- Baker S
- Balek P
- Balli F
- Banas E
- Banerjee P
- Banerjee S
- Banfi D
- Bangert A
- Bansal V
- Bansil HS
- Barak L
- Baranov SP
- Barber T
- Barberio EL
- Barberis D
- Barbero M
- Bardin DY
- Barillari T
- Barisonzi M
- Barklow T
- Barlow N
- Barnett BM
- Barnett RM
- Baroncelli A
- Barone G
- Barr AJ
- Barreiro GuimarĂŁes da Costa J
- Barreiro F
- Bartoldus R
- Barton AE
- Bartsch V
- Basye A
- Bates RL
- Batkova L
- Batley JR
- Battaglia A
- Battistin M
- Bauer F
- Bawa HS
- Beale S
- Beau T
- Beauchemin PH
- Beccherle R
- Bechtle P
- Beck HP
- Becker K
- Becker S
- Beckingham M
- Becks KH
- Beddall A
- Beddall AJ
- Bedikian S
- Bednyakov VA
- Bee CP
- Beemster LJ
- Beermann TA
- Begel M
- Behar Harpaz S
- Belanger-Champagne C
- Bell PJ
- Bell WH
- Bella G
- Bellagamba L
- Bellomo M
- Belloni A
- Beloborodova O
- Belotskiy K
- Beltramello O
- Benary O
- Benchekroun D
- Bendtz K
- Benekos N
- Benhammou Y
- Benhar Noccioli E
- Benitez Garcia JA
- Benjamin DP
- Benoit M
- Bensinger JR
- Benslama K
- Bentvelsen S
- Berge D
- Bergeaas Kuutmann E
- Berger N
- Berghaus F
- Berglund E
- Beringer J
- Bernat P
- Bernhard R
- Bernius C
- Bernlochner FU
- Berry T
- Bertella C
- Bertin A
- Bertolucci F
- Besana MI
- Besjes GJ
- Besson N
- Bethke S
- Bhimji W
- Bianchi RM
- Bianchini L
- Bianco M
- Biebel O
- Bieniek SP
- Bierwagen K
- Biesiada J
- Biglietti M
- Bilokon H
- Bindi M
- Binet S
- Bingul A
- Bini C
- Biscarat C
- Bittner B
- Black CW
- Black JE
- Black KM
- Blair RE
- Blanchard JB
- Blazek T
- Bloch I
- Blocker C
- Blocki J
- Blum W
- Blumenschein U
- Bobbink GJ
- Bobrovnikov VS
- Bocchetta SS
- Bocci A
- Boddy CR
- Boehler M
- Boek J
- Boek TT
- Boelaert N
- Bogaerts JA
- Bogdanchikov A
- Bogouch A
- Bohm C
- Bohm J
- Boisvert V
- Bold T
- Boldea V
- Bolnet NM
- Bomben M
- Bona M
- Boonekamp M
- Bordoni S
- Borer C
- Borisov A
- Borissov G
- Borjanovic I
- Borri M
- Borroni S
- Bortfeldt J
- Bortolotto V
- Bos K
- Boscherini D
- Bosman M
- Boterenbrood H
- Bouchami J
- Boudreau J
- Bouhova-Thacker EV
- Boumediene D
- Bourdarios C
- Bousson N
- Boutouil S
- Boveia A
- Boyd J
- Boyko IR
- Bozovic-Jelisavcic I
- Bracinik J
- Branchini P
- Brandt A
- Brandt G
- Brandt O
- Bratzler U
- Brau B
- Brau JE
- Braun HM
- Brazzale SF
- Brelier B
- Bremer J
- Brendlinger K
- Brenner R
- Bressler S
- Bristow TM
- Britton D
- Brochu FM
- Brock I
- Brock R
- Broggi F
- Bromberg C
- Bronner J
- Brooijmans G
- Brooks T
- Brooks WK
- Brown G
- Bruckman de Renstrom PA
- Bruncko D
- Bruneliere R
- Brunet S
- Bruni A
- Bruni G
- Bruschi M
- Bryngemark L
- Buanes T
- Buat Q
- Bucci F
- Buchanan J
- Buchholz P
- Buckingham RM
- Buckley AG
- Buda SI
- Budagov IA
- Budick B
- Bugge L
- Bulekov O
- Bundock AC
- Bunse M
- Buran T
- Burckhart H
- Burdin S
- Burgess T
- Burke S
- Busato E
- Bussey P
- Buszello CP
- Butler B
- Butler JM
- Buttar CM
- Butterworth JM
- Buttinger W
- Byszewski M
- BĂŒscher V
- Cabrera UrbĂĄn S
- Caforio D
- Cakir O
- Calafiura P
- Calderini G
- Calfayan P
- Calkins R
- Caloba LP
- Caloi R
- Calvet D
- Calvet S
- Camacho Toro R
- Camarri P
- Cameron D
- Caminada LM
- Caminal Armadans R
- Campana S
- Campanelli M
- Canale V
- Canelli F
- Canepa A
- Cantero J
- Cantrill R
- Cao T
- Capeans Garrido MD
- Caprini I
- Caprini M
- Capriotti D
- Capua M
- Caputo R
- Cardarelli R
- Carli T
- Carlino G
- Carminati L
- Caron S
- Carquin E
- Carrillo-Montoya GD
- Carter AA
- Carter JR
- Carvalho J
- Casadei D
- Casado MP
- Cascella M
- Caso C
- Castaneda-Miranda E
- Castillo Gimenez V
- Castro NF
- Cataldi G
- Catastini P
- Catinaccio A
- Catmore JR
- Cattai A
- Cattani G
- Caughron S
- Cavaliere V
- Cavalleri P
- Cavalli D
- Cavalli-Sforza M
- Cavasinni V
- Ceradini F
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cetin SA
- Chafaq A
- Chakraborty D
- Chalupkova I
- Chan K
- Chang P
- Chapleau B
- Chapman JD
- Chapman JW
- Charlton DG
- Chavda V
- Chavez Barajas CA
- Cheatham S
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chelstowska MA
- Chen C
- Chen H
- Chen S
- Chen X
- Chen Y
- Cheng Y
- Cheplakov A
- Cherkaoui El Moursli R
- Chernyatin V
- Cheu E
- Cheung SL
- Chevalier L
- Chiefari G
- Chikovani L
- Childers JT
- Chilingarov A
- Chiodini G
- Chisholm AS
- Chislett RT
- Chitan A
- Chizhov MV
- Choudalakis G
- Chouridou S
- Chow BK
- Christidi IA
- Christov A
- Chromek-Burckhart D
- Chu ML
- Chudoba J
- Ciapetti G
- Ciftci AK
- Ciftci R
- Cinca D
- Cindro V
- Ciocio A
- Cirilli M
- Cirkovic P
- Citron ZH
- Citterio M
- Ciubancan M
- Clark A
- Clark PJ
- Clarke RN
- Cleland W
- Clemens JC
- Clement B
- Clement C
- Coadou Y
- Cobal M
- Coccaro A
- Cochran J
- Coffey L
- Cogan JG
- Coggeshall J
- Colas J
- Cole B
- Cole S
- Colijn AP
- Collins NJ
- Collins-Tooth C
- Collot J
- Colombo T
- Colon G
- Compostella G
- Conde Muiño P
- Coniavitis E
- Conidi MC
- Consonni SM
- Consorti V
- Constantinescu S
- Conta C
- Conti G
- Conventi F
- Cooke M
- Cooper BD
- Cooper-Sarkar AM
- Copic K
- Cornelissen T
- Corradi M
- Corriveau F
- Cortes-Gonzalez A
- Cortiana G
- Costa G
- Costa MJ
- Costanzo D
- Cottin G
- Courneyea L
- Cowan G
- Cox BE
- Cranmer K
- Crescioli F
- Cristinziani M
- Crosetti G
- Crépé-Renaudin S
- Cuciuc CM
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- Shan LY
- Shank JT
- Shao QT
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- Shatalov PB
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- Sherwood P
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- Shimojima M
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- Shmeleva A
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- Sliwa K
- Smakhtin V
- Smart BH
- Smestad L
- Smirnov SY
- Smirnov Y
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- Smith KM
- Smizanska M
- Smolek K
- Snesarev AA
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- Snow SW
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- Sobie R
- Sodomka J
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- Solfaroli Camillocci E
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- Solovyanov OV
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- Stekl I
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- Swedish S
- Swiatlowski M
- Sykora I
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- Ta D
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- Thompson EN
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- Thompson PD
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- Thong WM
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- Tian F
- Tibbetts MJ
- Tic T
- Tikhomirov VO
- Tikhonov YA
- Timoshenko S
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- Todorov T
- Todorova-Nova S
- Toggerson B
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- Tsukerman II
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- Tudorache V
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- Turk Cakir I
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- Tyndel M
- Tzanakos G
- Uchida K
- Ueda I
- Ueno R
- Ughetto M
- Ugland M
- Uhlenbrock M
- Ukegawa F
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- Valladolid Gallego E
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- van Vulpen I
- Vanadia M
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- Vaniachine A
- Vankov P
- Vannucci F
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- Varnes EW
- Varol T
- Varouchas D
- Vartapetian A
- Varvell KE
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- Vazeille F
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- Veloso F
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- Vickey Boeriu OE
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- Villaplana Perez M
- Vilucchi E
- Vincter MG
- Vinek E
- Vinogradov VB
- Virzi J
- Vitells O
- Viti M
- Vivarelli I
- Vives Vaque F
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- Vladoiu D
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- Volpi G
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- von der Schmitt H
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- Vorobel V
- Vorwerk V
- Vos M
- Voss R
- Vossebeld JH
- Vranjes Milosavljevic M
- Vranjes N
- Vrba V
- Vreeswijk M
- Vu Anh T
- Vuillermet R
- Vukotic I
- Vykydal Z
- Wagner P
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- Wahlen H
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- Wakabayashi J
- Walch S
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- Warburton A
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- Washbrook A
- Wasicki C
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- Wengler T
- Wenig S
- Wermes N
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- Werth M
- Wessels M
- Wetter J
- Weydert C
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- Wienemann P
- Wiglesworth C
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- Wijeratne PA
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- Wildt MA
- Wilhelm I
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- Willocq S
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- Wilson JA
- Wilson MG
- Wingerter-Seez I
- Winkelmann S
- Winklmeier F
- Wittgen M
- Wittig T
- Wittkowski J
- Wollstadt SJ
- Wolter MW
- Wolters H
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- Wooden G
- Wosiek BK
- Wotschack J
- Woudstra MJ
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- Wraight K
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- Wrona B
- Wu SL
- Wu X
- Wu Y
- Wulf E
- Wynne BM
- Xella S
- Xiao M
- Xie S
- Xu C
- Xu D
- Xu L
- Yabsley B
- Yacoob S
- Yamada M
- Yamaguchi H
- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamauchi K
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang H
- Yang UK
- Yang Y
- Yang Z
- Yanush S
- Yao L
- Yasu Y
- Yatsenko E
- Ye J
- Ye S
- Yen AL
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJ
- Youssef S
- Yu D
- Yu DR
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zambito S
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zenin O
- ZeniĆĄ T
- Zerwas D
- Zevi Della Porta G
- Zhang D
- Zhang H
- Zhang J
- Zhang L
- Zhang X
- Zhang Z
- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- ZivkoviÄ L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- American Physical Society
- Publication date
- 01/01/2012
- Field of study
Two-particle correlations in relative azimuthal angle (ÎÏ) and pseudorapidity (Îη) are measured in âsNN=5.02ââTeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1ââÎŒb-1 of data as a function of transverse momentum (pT) and the transverse energy (ÎŁETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Îη|<5) ânear-sideâ (ÎÏâŒ0) correlation that grows rapidly with increasing ÎŁETPb. A long-range âaway-sideâ (ÎÏâŒÏ) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ÎŁETPb, is found to match the near-side correlation in magnitude, shape (in Îη and ÎÏ) and ÎŁETPb dependence. The resultant ÎÏ correlation is approximately symmetric about Ï/2, and is consistent with a dominant cosâĄ2ÎÏ modulation for all ÎŁETPb ranges and particle pT
Search for R-parity-violating supersymmetry in events with four or more leptons in sqrt(s) =7 TeV pp collisions with the ATLAS detector
- Author
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- Abajyan T
- Abbott B
- Abdallah J
- Khalek SA
- Abdelalim AA
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- della Porta GZ
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- Zhemchugov A
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- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Collaboration ATLAS
- Publication venue
- Springer Verlag
- Publication date
- 01/01/2008
- Field of study
A search for new phenomena in final states with four or more leptons (electrons or muons) is presented. The analysis is based on 4.7 fbâ1 of sâ=7TeV proton-proton collisions delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in two signal regions: one that requires moderate values of missing transverse momentum and another that requires large effective mass. The results are interpreted in a simplified model of R-parity-violating supersymmetry in which a 95% CL exclusion region is set for charged wino masses up to 540 GeV. In an R-parity-violating MSUGRA/CMSSM model, values of m 1/2 up to 820 GeV are excluded for 10 < tan ÎČ < 40
Search for high-mass resonances decaying to dilepton final states in pp collisions at sâ=7 TeV with the ATLAS detector
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- Yanush S
- Yao L
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- Yildiz HD
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJ
- Youssef S
- Yu D
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- Yu J
- Yu J
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- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
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- Zenin O
- Zenis T
- Zerwas D
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- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
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- Zhu H
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- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- Springer
- Publication date
- 23/11/2012
- Field of study
The ATLAS detector at the Large Hadron Collider is used to search for high-mass resonances decaying to an electron-positron pair or a muon-antimuon pair. The search is sensitive to heavy neutral ZâČ gauge bosons, Randall-Sundrum gravitons, Z * bosons, techni-mesons, Kaluza-Klein Z/Îł bosons, and bosons predicted by Torsion models. Results are presented based on an analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 4.9 fbâ1 in the e + e â channel and 5.0 fbâ1 in the ÎŒ + ÎŒ âchannel. A Z âČ boson with Standard Model-like couplings is excluded at 95 % confidence level for masses below 2.22 TeV. A Randall-Sundrum graviton with coupling k/MPl=0.1 is excluded at 95 % confidence level for masses below 2.16 TeV. Limits on the other models are also presented, including Technicolor and Minimal ZâČ Models
Search for the neutral Higgs bosons of the minimal supersymmetric standard model in pp collisions at root s=7 TeV with the ATLAS detector
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdinov O
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Acharya BS
- Adam ER
- Adamczyk L
- Adams DL
- Addy TN
- Adelman J
- Adomeit S
- Adragna P
- Adye T
- Aesky S
- Agar-Savedra JA
- Agustoni M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
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- Alimonti G
- Alison J
- Allbrooke BMM
- Allison LJ
- Allport PP
- Allwood-Spiers SE
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- Alviggi MG
- Amako K
- Amelung C
- Ammosov VV
- Amor Dos Santos SP
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- Amoroso S
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- Anders CF
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- Anderson KJ
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- Anghinolfi F
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- Anisenkov A
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- Antonaki A
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- Barojas CAC
- Baroncelli A
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- Barreiro F
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- Publication venue
- Publication date
- 01/02/2013
- Field of study
A search for neutral Higgs bosons of the Minimal Supersymmetric Standard Model (MSSM) is reported. The analysis is based on a sample of proton-proton collisions at a centre-of-mass energy of 7TeV recorded with the ATLAS detector at the Large Hadron Collider. The data were recorded in 2011 and correspond to an integrated luminosity of 4.7 fb-1 to 4.8 fb-1. Higgs boson decays into oppositely-charged muon or Ï lepton pairs are considered for final states requiring either the presence or absence of b-jets. No statistically significant excess over the expected background is observed and exclusion limits at the 95% confidence level are derived. The exclusion limits are for the production cross-section of a generic neutral Higgs boson, Ï, as a function of the Higgs boson mass and for h/A/H production in the MSSM as a function of the parameters mA and tan ÎČ in the mhmax scenario for mA in the range of 90GeV to 500 GeV. Copyright CERN
Measurement of the cross-section of high transverse momentum vector bosons reconstructed as single jets and studies of jet substructure in pp collisions at âs = 7 TeV with the ATLAS detector
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- Floderus A
- Florez Bustos AC
- Flowerdew MJ
- Flowerdew MJ
- Formica A
- Formica A
- Forti A
- Forti A
- Fortin D
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- Fournier D
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- Fox H
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- Francavilla P
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- Franchini M
- Franchini M
- Franchino S
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- Francis D
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- Franklin M
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- Franz S
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- Fraternali M
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- Fratin S
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- French ST
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- Friedrich C
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- Friedrich F
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- Frost JA
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- Fulsom BG
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- Gabizon O
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- Gabrielli A
- Gabrielli A
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- Gadatsch S
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- Gadomski S
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- Gagliardi G
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- Galhardo B
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- Gallas EJ
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- Gallo V
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- Gallop BJ
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- Gandrajula RP
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- Gaob J
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- Garcia C
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- Garcia JAB
- Garcia-Sciveres M
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- Gardner RW
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- Garelli N
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- Garonne V
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- Garrido MDMC
- Gatti C
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- Gaudio G
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- Gaur B
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- Gauzzi P
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- Gavrilenko IL
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- Ge P
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- Gecse Z
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- Gee CNP
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- Geich-Gimbel C
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- Gemme C
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- Gemmell A
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- Genest MH
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- Gentile S
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- George M
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- George S
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- Gerbaudo D
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- Gershon A
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- Ghazlane H
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- Ghodbane N
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- Giacobbe B
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- Giangiobbe V
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- Giannetti P
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- Gianotti F
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- Gibbard B
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- Gilchriese M
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- Gillam TPS
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- Gillberg D
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- Gillman AR
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- Gingrich M
- Giokaris N
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- Giordani MP
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- Giordano R
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- Giugni D
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- Giuliani C
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- Giunta M
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- Gjelsten BK
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2014
- Field of study
This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to all-hadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of âs = 7 TeV;{\rm Te}{\rm V}andcorrespondtoanintegratedluminosityof4.6\;{\rm f}{{{\rm b}}^{-1}}.ThemeasurementisperformedbyreconstructingtheboostedWorZbosonsinsinglejets.ThereconstructedjetmassisusedtoidentifytheWandZbosons,andajetsubstructuremethodbasedonenergyclusterinformationinthejetcentreâofâmassframeisusedtosuppressthelargemultiâjetbackground.ThecrossâsectionforeventswithahadronicallydecayingWorZboson,withtransversemomentum{{p}_{{\rm T}}}\gt 320\;{\rm Ge}{\rm V}andpseudorapidity|\eta |\lt 1.9,ismeasuredtobe{{\sigma }_{W+Z}}=8.5\pm 1.7$ pb and is compared to next-to-leading-order calculations. The selected events are further used to study jet grooming techniques
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