147 research outputs found
Apollo Lunar Sounder digital data deconvolution
The purpose of the work reported on herein was to demonstrate the possibility of enhancing the subsurface feature detection probability by digital processing and filtering.Rolando Jordan.Introduction -- Description of the procedure -- Phase error detection procedure -- Conclusion
Spaceborne synthetic-aperture imaging radars: Applications, techniques, and technology
In the last four years, the first two Earth-orbiting, space-borne, synthetic-aperture imaging radars (SAR) were successfully developed and operated. This was a major achievement in the development of spaceborne radar sensors and ground processors. The data acquired with these sensors extended the capability of Earth resources and ocean-surface observation into a new region of the electromagnetic spectrum. This paper is a review of the different aspects of spaceborne imaging radars. It includes a review of: 1) the unique characteristics of space-borne SAR systems; 2) the state of the art in spaceborne SAR hardware and SAR optical and digital processors; 3) the different data-handling techniques; and 4) the different applications of spaceborne SAR data
Colorimetría y densitometría en madera de Guazuma crinita
En el presente trabajo se determinaron los parámetros colorimétricos mediante el sistema CIELAB y la densidad aparente por densitometría de rayos X en madera de Guazuma crinita para obtener información de su calidad en el uso como madera solida o transformada. La evaluación se realizó en tres niveles del eje axial (basal, medio y apical) de una plantación de 5 y 8 años, en la zona de Puerto Inca, departamento de Huánuco, Perú. En ambas edades, empleando el sistema CIElab, se encontró que la madera es de coloración homogénea y se clasifica como rosa grisáceo. La densidad aparente medida por densitometría de rayos X en el sentido médula - corteza fue de 0,52 g/cm3 y 0,56 g/cm3 para 5 y 8 años respectivamente; con promedios mayores en el nivel basal (5 años: 0,65; 8 años:0,68) y menores en el nivel apical (5 años: 0,43; 8 años: 0,47). Los perfiles densitométricos mostraron, en general, que radialmente hay un aumento de la densidad aparente en el sentido médula - corteza. La densidad de la madera madera de 5 años resultó más uniforme que la de 8 años con un índice de uniformidad de 149,7 y 170,3, respectivamente
Spaceborne synthetic-aperture imaging radars: Applications, techniques, and technology
In the last four years, the first two Earth-orbiting, space-borne, synthetic-aperture imaging radars (SAR) were successfully developed and operated. This was a major achievement in the development of spaceborne radar sensors and ground processors. The data acquired with these sensors extended the capability of Earth resources and ocean-surface observation into a new region of the electromagnetic spectrum. This paper is a review of the different aspects of spaceborne imaging radars. It includes a review of: 1) the unique characteristics of space-borne SAR systems; 2) the state of the art in spaceborne SAR hardware and SAR optical and digital processors; 3) the different data-handling techniques; and 4) the different applications of spaceborne SAR data
X band model of Venus atmosphere permittivity
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/94912/1/rds5697.pd
Principles of Hand Fracture Management
The hand is essential in humans for physical manipulation of their surrounding environment. Allowing the ability to grasp, and differentiated from other animals by an opposing thumb, the main functions include both fine and gross motor skills as well as being a key tool for sensing and understanding the immediate surroundings of their owner
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
Background:
Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke.
Methods:
We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515.
Findings:
Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p<0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (<1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (<1%) deaths in the albiglutide group.
Interpretation:
In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes.
Funding:
GlaxoSmithKline
Estudios de Caso sobre Ciencias Agropecuarias y Rurales en el siglo XXI.
Libro científico sobre estudios de casos en el medio agropecuario y ruralCon el advenimiento del siglo XXI y el avance de los procesos de globalización, el medio rural presenta diversos cambios económicos, sociales, políticos y culturales. Lo anterior significa que el campo es un objeto de estudio altamente dinámico, complejo e inasible. las ciencias agropecuarias y rurales, en la actualidad, requieren de un abordaje sistémico e interdisciplinario que den cuenta de la heterogeneidad de situaciones y contextos que enfrenta el campo mexicano. La presente obra agrupa 18 estudios de caso, que capturan algunas fotografías de las diversas problemáticas de la ruralidad mexicana, con lo cual se pretende dar cuenta tanto de los objetivos de estudio como de la perspectiva teórico metodológico desde que estos son abordados. lo anterior tiene que ver con el hecho de que las ciencias agropecuarias y rurales manifiestan un alto grado de observación empírica, motivo por el que los estudios de caso se convierten en la perspectiva metodológica idónea que permite ir y venir de la realidad a la teoría y viceversa para la construcción de objetos de estudio. En este volumen se aborda una gran diversidad de casos, que sintetizan la heterogeneidad de enfoques y perspectivas mediante las cuales los fenómenos agropecuarios y rurales han sido abordados en el Instituto de Ciencias Agropecuarias y Rurales de la Universidad Autónoma del Estado de México, en los últimos 30 años
Many Labs 2: Investigating Variation in Replicability Across Samples and Settings
We conducted preregistered replications of 28 classic and contemporary published findings, with protocols that were peer reviewed in advance, to examine variation in effect magnitudes across samples and settings. Each protocol was administered to approximately half of 125 samples that comprised 15,305 participants from 36 countries and territories. Using the conventional criterion of statistical significance (p < .05), we found that 15 (54%) of the replications provided evidence of a statistically significant effect in the same direction as the original finding. With a strict significance criterion (p < .0001), 14 (50%) of the replications still provided such evidence, a reflection of the extremely highpowered design. Seven (25%) of the replications yielded effect sizes larger than the original ones, and 21 (75%) yielded effect sizes smaller than the original ones. The median comparable Cohen’s ds were 0.60 for the original findings and 0.15 for the replications. The effect sizes were small (< 0.20) in 16 of the replications (57%), and 9 effects (32%) were in the direction opposite the direction of the original effect. Across settings, the Q statistic indicated significant heterogeneity in 11 (39%) of the replication effects, and most of those were among the findings with the largest overall effect sizes; only 1 effect that was near zero in the aggregate showed significant heterogeneity according to this measure. Only 1 effect had a tau value greater than .20, an indication of moderate heterogeneity. Eight others had tau values near or slightly above .10, an indication of slight heterogeneity. Moderation tests indicated that very little heterogeneity was attributable to the order in which the tasks were performed or whether the tasks were administered in lab versus online. Exploratory comparisons revealed little heterogeneity between Western, educated, industrialized, rich, and democratic (WEIRD) cultures and less WEIRD cultures (i.e., cultures with relatively high and low WEIRDness scores, respectively). Cumulatively, variability in the observed effect sizes was attributable more to the effect being studied than to the sample or setting in which it was studied.UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Sociales::Instituto de Investigaciones Psicológicas (IIP
American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus
10.1002/acr.23834ARTHRITIS CARE & RESEARCH715579-59
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