All-sky component separation for the Planck mission

An harmonic-space maximum-entropy method (MEM) is presented for separating the emission from different physical components in all-sky observations by the forthcoming Planck satellite. The analysis is performed at full Planck resolution, with a pixel size of 1.7 arcmin, which corresponds to a maximum multipole of around 6000. The simulated Planck data include emission from the CMB, the kinetic and thermal Sunyaev-Zel'dovich (SZ) effects from galaxy clusters, as well as Galactic dust, free-free and synchrotron emission. Our simulations also assume homogeneous, uncorrelated pixel noise, although this is not a requirement of the method. We find that the MEM technique produces faithful reconstructions of the main input components over the whole sky, without the need to perform a Galactic cut. The CMB power spectrum is accurately recovered up to a multipole of around 2000. The algorithm is parallelised so that the entire reconstruction can be performed in around 6 hr using 30 R10000 processors on an SGI Origin 2000 supercomputer and requires 14 Gb of memory.Comment: 16 pages, 13 figures; changed to match version accepted by MNRAS. Version with high-resolution figures available from http://www.mrao.cam.ac.uk/projects/cpac/pub.htm

Survey of O VI absorption in the Large Magellanic Cloud

We present a survey of interstellar O VI absorption in the Large Magellanic Cloud (LMC) towards 70 lines of sight based on Far Ultraviolet Spectroscopic Explorer (FUSE) observations. The survey covers O VI absorption in a large number of objects in different environmental conditions of the LMC. Overall, a high abundance of O VI is present in active and inactive regions of the LMC with mean log[N(O VI)] = 14.23 atoms cm$^{-2}$. There is no correlation observed between O VI absorption and emissions from the hot gas (X-ray surface brightness) or the warm gas (H$_{\alpha}$ surface brightness). O VI absorption in the LMC is patchy and the properties are similar to that of the Milky Way (MW). In comparison to the Small Magellanic Cloud (SMC), O VI is lower in abundance even though SMC has a lower metallicity compared to the LMC and the MW. We present observations in 10 superbubbles of the LMC of which we detect O VI absorption in 5 superbubbles for the first time and the superbubbles show an excess O VI absorption of about 40% compared to non-superbubble lines of sight. We have also studied the properties of O VI absorption in the 30 Doradus region. Even though O VI does not show any correlation with X-ray emission for the LMC, a good correlation between log[N(O VI)] and X-ray surface brightness for 30 Doradus region is present. We also find that O VI abundance decreases with increasing distance from the star cluster R136.Comment: 25 pages, 9 figures. Accepted for publication in MNRA

Zeta Oph and the weak-wind problem

Mass-loss rate, $\dot{M}$, is one of the key parameters affecting evolution and observational manifestations of massive stars, and their impact on the ambient medium. Despite its importance, there is a factor of ~100 discrepancy between empirical and theoretical $\dot{M}$ of late-type O dwarfs, the so-called weak-wind problem. In this Letter, we propose a simple novel method to constrain $\dot{M}$ of runaway massive stars through observation of their bow shocks and Stromgren spheres, which might be of decisive importance for resolving the weak-wind problem. Using this method, we found that $\dot{M}$ of the well-known runaway O9.5 V star zeta Oph is more than an order of magnitude higher than that derived from ultraviolet (UV) line-fitting (Marcolino et al. 2009) and is by a factor of 6 to 7 lower than those based on the theoretical recipe by Vink et al. (2000) and the Halpha line (Mokiem et al. 2005). The discrepancy between $\dot{M}$ derived by our method and that based on UV lines would be even more severe if the stellar wind is clumpy. At the same time, our estimate of $\dot{M}$ agrees with that predicted by the moving reversing layer theory by Lucy (2010).Comment: 5 pages, 1 figure, 2 tables. Accepted for publication in MNRAS Letter

Human platelet lysate as a fetal bovine serum substitute improves human adipose-derived stromal cell culture for future cardiac repair applications

Adipose-derived stromal cells (ASC) are promising candidates for cell therapy, for example to treat myocardial infarction. Commonly, fetal bovine serum (FBS) is used in ASC culturing. However, FBS has several disadvantages. Its effects differ between batches and, when applied clinically, transmission of pathogens and antibody development against FBS are possible. In this study, we investigated whether FBS can be substituted by human platelet lysate (PL) in ASC culture, without affecting functional capacities particularly important for cardiac repair application of ASC. We found that PL-cultured ASC had a significant 3-fold increased proliferation rate and a significantly higher attachment to tissue culture plastic as well as to endothelial cells compared with FBS-cultured ASC. PL-cultured ASC remained a significant 25% smaller than FBS-cultured ASC. Both showed a comparable surface marker profile, with the exception of significantly higher levels of CD73, CD90, and CD166 on PL-cultured ASC. PL-cultured ASC showed a significantly higher migration rate compared with FBS-cultured ASC in a transwell assay. Finally, FBS- and PL-cultured ASC had a similar high capacity to differentiate towards cardiomyocytes. In conclusion, this study showed that culturing ASC is more favorable in PL-supplemented medium compared with FBS-supplemented medium

GSH 006-15+7: A local Galactic supershell featuring transition from HI emission to absorption

We report on the discovery of a new Galactic supershell, GSH 006-15+7, from the Galactic All Sky Survey data. Observed and derived properties are presented and we find that GSH 006-15+7 is one of the nearest physically large supershells known, with dimensions of ~ 780 x 520 pc at a distance of ~ 1.5 kpc. The shell wall appears in HI emission at b <~ -6.5 deg and in HI self-absorption (HISA) at b >~ -6.5 deg. We use this feature along with HISA diagnostics to estimate an optical depth of tau ~ 3, a spin temperature of ~ 40 K and a swept-up mass of M ~ 3e6 solar masses. We also investigate the origin of GSH 006-15+7, assessing the energy contribution of candidate powering sources and finding evidence in favour of a formation energy of ~ 1e52 ergs. We find that this structure provides evidence for the transfer of mass and energy from the Galactic disk into the halo.Comment: 12 pages, 8 figures, accepted for publication in MNRA

Venous gas embolism as a predictive tool for improving CNS decompression safety

A key process in the pathophysiological steps leading to decompression sickness (DCS) is the formation of inert gas bubbles. The adverse effects of decompression are still not fully understood, but it seems reasonable to suggest that the formation of venous gas emboli (VGE) and their effects on the endothelium may be the central mechanism leading to central nervous system (CNS) damage. Hence, VGE might also have impact on the long-term health effects of diving. In the present review, we highlight the findings from our laboratory related to the hypothesis that VGE formation is the main mechanism behind serious decompression injuries. In recent studies, we have determined the impact of VGE on endothelial function in both laboratory animals and in humans. We observed that the damage to the endothelium due to VGE was dose dependent, and that the amount of VGE can be affected both by aerobic exercise and exogenous nitric oxide (NO) intervention prior to a dive. We observed that NO reduced VGE during decompression, and pharmacological blocking of NO production increased VGE formation following a dive. The importance of micro-nuclei for the formation of VGE and how it can be possible to manipulate the formation of VGE are discussed together with the effects of VGE on the organism. In the last part of the review we introduce our thoughts for the future, and how the enigma of DCS should be approached

Planck early results XX : New light on anomalous microwave emission from spinning dust grains

Peer reviewe

Planck intermediate results. XXIII. Galactic plane emission components derived from Planck with ancillary data

Planck data when combined with ancillary data provide a unique opportunity to separate the diffuse emission components of the inner Galaxy. The purpose of the paper is to elucidate the morphology of the various emission components in the strong star-formation region lying inside the solar radius and to clarify the relationship between the various components. The region of the Galactic plane covered is l = 300\ub0 \u2192 0\ub0 \u2192 60\ub0 wherestar-formation is highest and the emission is strong enough to make meaningful component separation. The latitude widths in this longitude range lie between 1 and 2, which correspond to FWHM z-widths of 100-200 pc at a typical distance of 6 kpc. The four emission components studied here are synchrotron, free-free, anomalous microwave emission (AME), and thermal (vibrational) dust emission. These components are identified by constructing spectral energy distributions (SEDs) at positions along the Galactic plane using the wide frequency coverage of Planck (28.4-857GHz) in combination with low-frequency radio data at 0.408-2.3 GHz plus WMAP data at 23-94 GHz, along with far-infrared (FIR) data from COBE-DIRBE and IRAS. The free-free component is determined from radio recombination line (RRL) data. AME is found to be comparable in brightness to the free-free emission on the Galactic plane in the frequency range 20-40 GHz with a width in latitude similar to that of the thermal dust; it comprises 45 \ub1 1% of the total 28.4 GHz emission in the longitude range l = 300\ub0 \u2192 0\ub0 \u2192 60\ub0. The free-free component is the narrowest, reflecting the fact that it is produced by current star-formation as traced by the narrow distribution of OB stars. It is the dominant emission on the plane between 60 and 100 GHz. RRLs from this ionized gas are used to assess its distance, leading to a free-free z-width of FWHM 48 100 pc. The narrow synchrotron component has a low-frequency brightness spectral index \u3b2synch 48 -2.7 that is similar to the broad synchrotron component indicating that they are both populated by the cosmic ray electrons of the same spectral index. The width of this narrow synchrotron component is significantly larger than that of the other three components, suggesting that it is generated in an assembly of older supernova remnants that have expanded to sizes of order 150 pc in 3 7 105 yr; pulsars of a similar age have a similar spread in latitude. The thermal dust is identified in the SEDs with average parameters of Tdust = 20.4 \ub1 0.4 K, \u3b2FIR = 1.94 \ub1 0.03 (> 353 GHz), and \u3b2mm = 1.67 \ub1 0.02 (< 353 GHz). The latitude distributions of gamma-rays, CO, and the emission in high-frequency Planck bands have similar widths, showing that they are all indicators of the total gaseous matter on the plane in the inner Galaxy. \ua9 ESO, 2015