Revisitando el género de chinches emboscadoras Neoanthylla Kormilev, 1951 (Reduviidae, Phymatinae)

Neoanthylla (Kormilev, 1951) es un género Neotropical de Phymatinae con tres especies válidas: Neoanthylla bucki (Kormilev), Neoanthylla horvathi (Handlirsch) y Neoanthylla peruviana Kormilev. Morfológicamente se caracteriza por el profémur alargado y ovalado con la superficie cuticular lisa y brillante; las procoxas largas y subiguales al mesofémur; la carina prosternal larga, alcanzando el margen anterior del mesosternum; y el abdomen entero posteriormente. Las especies de Neoanthylla están escasamente documentadas en la literatura y las estructuras genitales son desconocidas. Además, las especies brasileñas (N. bucki y N. horvathi) son conocidas sólo por hembras. Aquí, se revisa Neoanthylla, se actualizan las diagnosis de las especies válidas, se brindan imágenes de los holotipos de N. horvathi y N. peruviana, y se describe por primera vez el macho de N. horvathi, incluyendo los caracteres genitales.Neoanthylla (Kormilev, 1951) is a Neotropical genus of Phymatinae with three valid species: Neoanthylla bucki (Kormilev), Neoanthylla horvathi (Handlirsch), and Neoanthylla peruviana Kormilev. Morphologically, it is characterized by the elongated and oval profemur with the cuticular surface smooth and shiny; the procoxa long and subequal to the mesofemur; the prosternal carina long, reaching the anterior margin of the mesosternum; and the abdomen posteriorly entire. Neoanthylla species are scarcely documented in the literature, and the genital structures are unknown. In addition, the Brazilian species (N. bucki and N. horvathi) are known only by female specimens. Here, Neoanthylla is revisited, the diagnoses of the valid species are improved, images of the holotypes of N. horvathi and N. peruviana are provided, and the male of N. horvathi is described for the first time, including genital characters.Fil: Castro Huertas, Ana Valentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Entomología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Varela, Pablo Sebastian. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Entomología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Melo, María Cecilia. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Entomología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Factores asociados a accidentes in itinere en veterinarios de grandes animales

Los objetivos de este trabajo fueron estimar: a) la frecuencia de accidentes laborales in itinere (ALii), b) la existencia de factores asociados, c) la frecuencia y el tipo de lesiones resultantes y d) las pérdidas de días laborales en veterinarios de grandes animales de la Provincia de Buenos Aires. Se desarrolló un estudio transversal entrevistando 106 profesionales con un cuestionario estructurado (muestreo aleatorio simple, error: 6,4%, confianza: 95% y frecuencia previa: 15%). El análisis estadístico incluyó χ2, test exacto de Fisher, t de student y la búsqueda de agrupamientos espaciales utilizando InfoStat® y SatScan 9.2.®. El 78,3% de los entrevistados trabajaba de forma autónoma. Los medios de transporte utilizados fueron vehículo utilitario/camioneta (69,8%) o automóvil (30,2%) recorriendo 44.886,8±24.628 km/año. El 34,9% había tenido ALii, siendo más frecuentes en caminos rurales. No se detectaron conglomerados geográficos estadísticamente significativos. El 56,8% identificó más de un factor asociado a los Alii. Un número variable de conductores incumplió con las normas de seguridad vial vigentes. Se sugiere que los programas de educación continua incluyan todos los peligros a los cuales se ven enfrentados los profesionales veterinarios, no sólo aquellos de origen biológico.The objectives of this study were to estimate: a) the frequency of occupational accidents in itinere (OAii), b) their associated factors, c) the frequency and type of injuries suffered and d) the number of days off work veterinarians working with large animals in the Province of Buenos Aires. A cross-sectional study was conducted interviewing 106 veterinarians using a structured questionnaire (simple random sampling, error: 6.4%, confidence: 95% and previous frequency: 15%). The statistical analysis included χ2, Fisher’s exact test, Student’s t test and the search for spatial clusters using InfoStat® and SatScan 9.2.®. Most interviewees (78.3%) worked on their own. The means of transportation were trucks (69.8%) and cars (30.2%) covering 44,886.8 ± 24,628 km/ year. Thirty five out of 100 veterinarians had suffered OAii, being most frequent on country roads. No statistically significant geographic clusters were detected. More than half of the drivers (56.8%) identified more than one factor associated with the OAii. A variable number of drivers failed to comply with current safety regulations. It is suggested that continuing education programs should include all hazards faced by veterinarians, not only those of biological origin.EEA RafaelaFil: Huertas, Pablo Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; ArgentinaFil: Molineri, Ana Ines. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rafaela; ArgentinaFil: Leon, Emilio Arnaldo. Universidad de Buenos Aires; ArgentinaFil: Signorini, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; ArgentinaFil: Tarabla, Héctor Dante. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentin

Diagnóstico bacteriológico de tuberculosis bovina en bovinos reactores positivos a la prueba tuberculínica

Mycobacterium bovis es el agente causal de la tuberculosis bovina (TBB), enfermedad zoonótica que afecta la producción láctea y cárnica. En nuestro país, el diagnóstico se realiza a través de la prueba tuberculínica o intradermorreacción aplicándose en el pliegue anocaudal (PAC). Como complemento a la PAC se pueden llevar adelante estudios bacteriológicos a partir de diversas muestras biológicas como secreción nasal, leche y tejidos. A su vez, se puede observar el desarrollo de lesiones y su ubicación anatómica, además de colectar muestras para ser analizadas a través de bacteriología e histopatología. El objetivo de este estudio fue evaluar la presencia de M. bovis en muestras de secreciones nasales, leche y tejidos pertenecientes a bovinos PAC-positivos y caracterizar lesiones macro y microscópicas compatibles con la TBB. Fueron procesadas 744 muestras pertenecientes a 572 bovinos, provenientes de 24 rodeos lecheros de las provincias de Córdoba, Santa Fe y Buenos Aires. Todos ellos se encontraban, durante este estudio, en etapa de saneamiento presentando una baja prevalencia (entre 0,5 y 4%). Se aisló M. bovis en 12,4% (71/572) de los bovinos examinados. Dicho agente provino de muestras de tejidos 36,5% (38/104), seguido de leche 10,7% (23/214) y, por último, desecreciones nasales 3,9% (10/254). Por un lado, el estudio bacteriológico a partir de las muestras de leche y secreciones nasales presentó una limitada efectividad. Por otro lado, el análisis de tejidos resultó de mayor utilidad como diagnóstico complementario, permitiendo confirmar los casos sospechados de TBB.Mycobacterium bovis is the causative agent of bovine tuberculosis (BTB), considered a zoonotic disease. In our country, the diagnosis is based on the application of the tuberculin skin test (TST). Conventional culture, from various biological samples, can complement the TST test results. Regarding this, it is possible to perform sampling and subsequent analysis of nasal discharge, milk and tissues. The latter allows the observation of macroscopic lesions, the anatomical location in addition to collect biological samples to be analyzed by bacteriology and histopathology. The aim of this study was to evaluate the presence of M. bovis in samples of nasal secretions, milk and tissues in cattle PAC-positive and characterize gross and microscopic lesions compatible with BTB. A total of 744 samples belonging to 572 cattle from dairy herds in the provinces of Córdoba, Santa Fe and Buenos Aires, were processed. All of them were, during this study, in stage of control of BTB showing a low prevalence (between 0.5 to 4%). About 12.4% (71/572) M. bovis isolations from cattle examined was obtained. These isolations were from tissue samples 36.5% (38/104), followed by milk 10.7% (23/214) and nasal secretions 3.9% (10/254). Bacteriology from milk samples and nasal secretions were of limited effectiveness. On the other hand, tissue analysis was more useful as complementary diagnostic, allowing confirmation of suspected cases of BTB.Instituto de PatobiologíaFil: Garbaccio, Sergio Gabriel. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; ArgentinaFil: Delgado, Fernando Oscar. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; ArgentinaFil: Zumarraga, Martin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; ArgentinaFil: Rodriguez, Liliana Rita. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; ArgentinaFil: Huertas, Pablo Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; ArgentinaFil: Garro, Carlos Javier. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentin

Heterogeneity of prodromal Parkinson symptoms in siblings of Parkinson disease patients

Abstract: A prodromal phase of Parkinson’s disease (PD) may precede motor manifestations by decades. PD patients’ siblings are at higher risk for PD, but the prevalence and distribution of prodromal symptoms are unknown. The study objectives were (1) to assess motor and non-motor features estimating prodromal PD probability in PD siblings recruited within the European PROPAG-AGEING project; (2) to compare motor and non-motor symptoms to the well-established DeNoPa cohort. 340 PD siblings from three sites (Bologna, Seville, Kassel/Goettingen) underwent clinical and neurological evaluations of PD markers. The German part of the cohort was compared with German de novo PD patients (dnPDs) and healthy controls (CTRs) from DeNoPa. Fifteen (4.4%) siblings presented with subtle signs of motor impairment, with MDS-UPDRS-III scores not clinically different from CTRs. Symptoms of orthostatic hypotension were present in 47 siblings (13.8%), no different to CTRs (p = 0.072). No differences were found for olfaction and overall cognition; German-siblings performed worse than CTRs in visuospatial-executive and language tasks. 3/147 siblings had video-polysomnography-confirmed REM sleep behavior disorder (RBD), none was positive on the RBD Screening Questionnaire. 173/300 siblings had <1% probability of having prodromal PD; 100 between 1 and 10%, 26 siblings between 10 and 80%, one fulfilled the criteria for prodromal PD. According to the current analysis, we cannot confirm the increased risk of PD siblings for prodromal PD. Siblings showed a heterogeneous distribution of prodromal PD markers and probability. Additional parameters, including strong disease markers, should be investigated to verify if these results depend on validity and sensitivity of prodromal PD criteria, or if siblings’ risk is not elevated

Study of the B−→Λc+Λˉc−K−B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} decay

The decay $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ is studied in proton-proton collisions at a center-of-mass energy of $\sqrt{s}=13$ TeV using data corresponding to an integrated luminosity of 5 $\mathrm{fb}^{-1}$ collected by the LHCb experiment. In the $\Lambda_{c}^+ K^{-}$ system, the $\Xi_{c}(2930)^{0}$ state observed at the BaBar and Belle experiments is resolved into two narrower states, $\Xi_{c}(2923)^{0}$ and $\Xi_{c}(2939)^{0}$, whose masses and widths are measured to be $$m(\Xi_{c}(2923)^{0}) = 2924.5 \pm 0.4 \pm 1.1 \,\mathrm{MeV}, \\ m(\Xi_{c}(2939)^{0}) = 2938.5 \pm 0.9 \pm 2.3 \,\mathrm{MeV}, \\ \Gamma(\Xi_{c}(2923)^{0}) = \phantom{000}4.8 \pm 0.9 \pm 1.5 \,\mathrm{MeV},\\ \Gamma(\Xi_{c}(2939)^{0}) = \phantom{00}11.0 \pm 1.9 \pm 7.5 \,\mathrm{MeV},$$ where the first uncertainties are statistical and the second systematic. The results are consistent with a previous LHCb measurement using a prompt $\Lambda_{c}^{+} K^{-}$ sample. Evidence of a new $\Xi_{c}(2880)^{0}$ state is found with a local significance of $3.8\,\sigma$, whose mass and width are measured to be $2881.8 \pm 3.1 \pm 8.5\,\mathrm{MeV}$ and $12.4 \pm 5.3 \pm 5.8 \,\mathrm{MeV}$, respectively. In addition, evidence of a new decay mode $\Xi_{c}(2790)^{0} \to \Lambda_{c}^{+} K^{-}$ is found with a significance of $3.7\,\sigma$. The relative branching fraction of $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ with respect to the $B^{-} \to D^{+} D^{-} K^{-}$ decay is measured to be $2.36 \pm 0.11 \pm 0.22 \pm 0.25$, where the first uncertainty is statistical, the second systematic and the third originates from the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb public pages

Measurement of the ratios of branching fractions R(D∗)\mathcal{R}(D^{*}) and R(D0)\mathcal{R}(D^{0})

The ratios of branching fractions $\mathcal{R}(D^{*})\equiv\mathcal{B}(\bar{B}\to D^{*}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(\bar{B}\to D^{*}\mu^{-}\bar{\nu}_{\mu})$ and $\mathcal{R}(D^{0})\equiv\mathcal{B}(B^{-}\to D^{0}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(B^{-}\to D^{0}\mu^{-}\bar{\nu}_{\mu})$ are measured, assuming isospin symmetry, using a sample of proton-proton collision data corresponding to 3.0 fb${ }^{-1}$ of integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The tau lepton is identified in the decay mode $\tau^{-}\to\mu^{-}\nu_{\tau}\bar{\nu}_{\mu}$. The measured values are $\mathcal{R}(D^{*})=0.281\pm0.018\pm0.024$ and $\mathcal{R}(D^{0})=0.441\pm0.060\pm0.066$, where the first uncertainty is statistical and the second is systematic. The correlation between these measurements is $\rho=-0.43$. Results are consistent with the current average of these quantities and are at a combined 1.9 standard deviations from the predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb public pages

Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV

Search for supersymmetry in events with one lepton and multiple jets in proton-proton collisions at root s=13 TeV

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