39 research outputs found
Histone H3K9 Trimethylase Eggless Controls Germline Stem Cell Maintenance and Differentiation
- Author
- A Adamo
- A Ebert
- A Szakmary
- AJ Bannister
- B Brower-Toland
- B Hay
- B Ohlstein
- B Ohlstein
- BA Hay
- C Klattenhoff
- C Schultz
- C Seum
- CM Koch
- D Chen
- D Chen
- D Chen
- D Kirilly
- D Kirilly
- D Kirilly
- D Pasini
- DM McKearin
- E Clough
- E Decotto
- G Pennetta
- G Schotta
- H Lin
- Hong Tang
- J Margolis
- J Mis
- J Muller
- J Yoon
- JA Lessard
- JC Eissenberg
- JC Eissenberg
- Jeff Haug
- Jian Zhou
- JQ Ni
- Jungeun Park
- JZ Maines
- K Tsuneizumi
- Karen Staehling
- L Di Stefano
- L Manseau
- Lei Pan
- M Buszczak
- M Lachner
- M Liu
- M Stabell
- M Van Doren
- MO Casanueva
- Norbert Perrimon
- P Rangan
- PF Lasko
- R Xi
- R Xi
- S Bilodeau
- S Chen
- S Eliazer
- Su Wang
- T Akiyama
- T Kai
- T Xie
- T Xie
- T Xie
- TG Fazzio
- Ting Xie
- TY Tzeng
- William McDowell
- X Shen
- X Song
- X Song
- Xiaoxi Wang
- YH Loh
- Z Guo
- Z Jin
- Publication venue
- Public Library of Science
- Publication date
- 01/12/2011
- Field of study
Get PDFEpigenetic regulation plays critical roles in the regulation of cell proliferation, fate determination, and survival. It has been shown to control self-renewal and lineage differentiation of embryonic stem cells. However, epigenetic regulation of adult stem cell function remains poorly defined. Drosophila ovarian germline stem cells (GSCs) are a productive adult stem cell system for revealing regulatory mechanisms controlling self-renewal and differentiation. In this study, we show that Eggless (Egg), a H3K9 methyltransferase in Drosophila, is required in GSCs for controlling self-renewal and in escort cells for regulating germ cell differentiation. egg mutant ovaries primarily exhibit germ cell differentiation defects in young females and gradually lose GSCs with time, indicating that Egg regulates both germ cell maintenance and differentiation. Marked mutant egg GSCs lack expression of trimethylated H3K9 (H3k9me3) and are rapidly lost from the niche, but their mutant progeny can still differentiate into 16-cell cysts, indicating that Egg is required intrinsically to control GSC self-renewal but not differentiation. Interestingly, BMP-mediated transcriptional repression of differentiation factor bam in marked egg mutant GSCs remains normal, indicating that Egg is dispensable for BMP signaling in GSCs. Normally, Bam and Bgcn interact with each other to promote GSC differentiation. Interestingly, marked double mutant egg bgcn GSCs are still lost, but their progeny are able to differentiate into 16-cell cysts though bgcn mutant GSCs normally do not differentiate, indicating that Egg intrinsically controls GSC self-renewal through repressing a Bam/Bgcn-independent pathway. Surprisingly, RNAi-mediated egg knockdown in escort cells leads to their gradual loss and a germ cell differentiation defect. The germ cell differentiation defect is at least in part attributed to an increase in BMP signaling in the germ cell differentiation niche. Therefore, this study has revealed the essential roles of histone H3K9 trimethylation in controlling stem cell maintenance and differentiation through distinct mechanisms
HE-LHC: The High-Energy Large Hadron Collider – Future Circular Collider Conceptual Design Report Volume 4
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- Abada A.
- Abbrescia M.
- AbdusSalam S. S.
- Abdyukhanov I.
- Abelleira Fernandez J.
- Abramov A.
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- Adzic P. R.
- Agrawal P.
- Aguilar-Saavedra J. A.
- Aguilera-Verdugo J. J.
- Ahnen J. von
- Aiba M.
- Aichinger I.
- Aielli G.
- Akay A.
- Akhundov A.
- Aksakal H.
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- Publication venue
- Springer Verlag
- Publication date
- 09/02/2021
- Field of study
Get PDFIn response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC study covered an energy-frontier hadron collider (FCC-hh), a highest-luminosity high-energy lepton collider (FCC-ee), the corresponding 100 km tunnel infrastructure, as well as the physics opportunities of these two colliders, and a high-energy LHC, based on FCC-hh technology. This document constitutes the third volume of the FCC Conceptual Design Report, devoted to the hadron collider FCC-hh. It summarizes the FCC-hh physics discovery opportunities, presents the FCC-hh accelerator design, performance reach, and staged operation plan, discusses the underlying technologies, the civil engineering and technical infrastructure, and also sketches a possible implementation. Combining ingredients from the Large Hadron Collider (LHC), the high-luminosity LHC upgrade and adding novel technologies and approaches, the FCC-hh design aims at significantly extending the energy frontier to 100 TeV. Its unprecedented centre-of-mass collision energy will make the FCC-hh a unique instrument to explore physics beyond the Standard Model, offering great direct sensitivity to new physics and discoveries
FCC-ee: The Lepton Collider – Future Circular Collider Conceptual Design Report Volume 2
- Author
- Abada A.
- Abbrescia M.
- AbdusSalam S. S.
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- Wilkinson G.
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- Zupan J.
- Zurita J.
- Özcan V.
- Özdemir K.
- Publication venue
- Springer Verlag
- Publication date
- 14/11/2019
- Field of study
Get PDFFCC-ee: The Lepton Collider: Future Circular Collider Conceptual Design Report Volume 2
- Author
- Abada A
- Abbrescia M
- AbdusSalam SS
- Abdyukhanov I
- Abramov A
- Aburaia M
- Acar AO
- Adzic PR
- Agaliotis EL
- Agrawal P
- Aguilar-Saavedra JA
- Aguilera-Verdugo JJ
- Aiba M
- Aichinger I
- Aielli G
- Akay A
- Akhundov A
- Aksakal H
- Alaniz EC
- Albacete JL
- Albergo S
- Alekou A
- Aleksa M
- Aleksan R
- Alexahin Y
- Alia RG
- Alioli S
- Allanach BC
- Allport PP
- Altinli M
- Altmannshofer W
- Ambrosio G
- Amorim D
- Amstutz O
- Anderlini L
- Andreazza A
- Andreini M
- Andriatis A
- Andris C
- Andronic A
- Angelucci M
- Antinori F
- Antipov SA
- Antonelli M
- Antonello M
- Antonioli P
- Antusch S
- Anulli F
- Apolinario L
- Apollinari G
- Apollonio A
- Appelo D
- Appleby RB
- Apyan A
- Apyan A
- Arbey A
- Arbuzov A
- Arduini G
- Ari V
- Arias S
- Armesto N
- Arnaldi R
- Arsenyev SA
- Arzeo M
- Asai S
- Aslanides E
- Assmann RW
- Astapovych D
- Atanasov M
- Atieh S
- Attie D
- Auchmann B
- Audurier A
- Aull S
- Aumon S
- Aune S
- Avino F
- Avrillaud G
- Aydin G
- Azatov A
- Azuelos G
- Azzi P
- Azzolini O
- Azzurri P
- Bacchetta N
- Bacchiocchi E
- Bachacou H
- Baek YW
- Baglin V
- Bai Y
- Baird S
- Baker MJ
- Baldwin MJ
- Ball AH
- Ballarino A
- Banerjee S
- Barber DP
- Barducci D
- Barjhoux P
- Barna D
- Barnafoldi GG
- Barnes MJ
- Barr A
- Bartmann W
- Baryshevsky V
- Barzi E
- Bass SA
- Bastianin A
- Baudouy B
- Bauer F
- Bauer M
- Baumgartner T
- Bautista-Guzman I
- Bayindir C
- Beaudette F
- Bedeschi F
- Beguin M
- Behr JK
- Bellafont I
- Bellagamba L
- Bellegarde N
- Belli E
- Bellingeri E
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- Yilmaz A
- Yilmaz A
- Yoo H-D
- Yost SA
- You T
- Young C
- Yu F
- Yu T-T
- Zaborowska A
- Zadeh SG
- Zadeh SG
- Zahnd M
- Zanetti M
- Zanotto L
- Zawiejski L
- Zeiler P
- Zerlauth M
- Zernov SM
- Zhang C
- Zhang H
- Zhang Y
- Zhang Z
- Zhao Z
- Zhong Y-M
- Zhou D
- Zhou J
- Zhuang P
- Zick G
- Zimmermann F
- Zinn-Justin J
- Zivkovic L
- Zlobin AV
- Zobov M
- Zupan J
- Zurita J
- Publication venue
- SPRINGER HEIDELBERG
- Publication date
- 01/06/2019
- Field of study
Get PDFIn response to the 2013 Update of the European Strategy for Particle Physics, the Future Circular Collider (FCC) study was launched, as an international collaboration hosted by CERN. This study covers a highest-luminosity high-energy lepton collider (FCC-ee) and an energy-frontier hadron collider (FCC-hh), which could, successively, be installed in the same 100 km tunnel. The scientific capabilities of the integrated FCC programme would serve the worldwide community throughout the 21st century. The FCC study also investigates an LHC energy upgrade, using FCC-hh technology. This document constitutes the second volume of the FCC Conceptual Design Report, devoted to the electron-positron collider FCC-ee. After summarizing the physics discovery opportunities, it presents the accelerator design, performance reach, a staged operation scenario, the underlying technologies, civil engineering, technical infrastructure, and an implementation plan. FCC-ee can be built with today’s technology. Most of the FCC-ee infrastructure could be reused for FCC-hh. Combining concepts from past and present lepton colliders and adding a few novel elements, the FCC-ee design promises outstandingly high luminosity. This will make the FCC-ee a unique precision instrument to study the heaviest known particles (Z, W and H bosons and the top quark), offering great direct and indirect sensitivity to new physics
FCC Physics Opportunities: Future Circular Collider Conceptual Design Report Volume 1
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- Abada A
- Abbrescia M
- AbdusSalam SS
- Abdyukhanov I
- Abramov A
- Aburaia M
- Acar AO
- Adzic PR
- Agrawal P
- Aguilar-Saavedra JA
- Aguilera-Verdugo JJ
- Ahnen JV
- Aiba M
- Aichinger I
- Aielli G
- Akay A
- Akhundov A
- Aksakal H
- Alaniz EC
- Albacete JL
- Albergo S
- Alekou A
- Aleksa M
- Aleksan R
- Alexahin Y
- Alia RG
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- Altmannshofer W
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- Wulzer A
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- Yang G
- Yang HJ
- Yao W-M
- Yazgan E
- Yermolchik V
- Yildiz HD
- Yilmaz A
- Yilmaz A
- Yoo H-D
- Yost SA
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- Zaborowska A
- Zadeh SG
- Zadeh SG
- Zahnd M
- Zanetti M
- Zanotto L
- Zawiejski L
- Zeiler P
- Zerlauth M
- Zernov SM
- Zevi Dell Porta G
- Zhang C
- Zhang H
- Zhang Y
- Zhang Z
- Zhao Z
- Zhong Y-M
- Zhou D
- Zhou J
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- Zick G
- Zimmermann F
- Zinn-Justin J
- Zivkovic L
- Zlobin AV
- Zobov M
- Zupan J
- Zurita J
- Publication venue
- 'Springer Fachmedien Wiesbaden GmbH'
- Publication date
- 01/06/2019
- Field of study
Get PDFWe review the physics opportunities of the Future Circular Collider, covering its e+e-, pp, ep and heavy ion programmes. We describe the measurement capabilities of each FCC component, addressing the study of electroweak, Higgs and strong interactions, the top quark and flavour, as well as phenomena beyond the Standard Model. We highlight the synergy and complementarity of the different colliders, which will contribute to a uniquely coherent and ambitious research programme, providing an unmatchable combination of precision and sensitivity to new physics
HE-LHC: The High-Energy Large Hadron Collider: Future Circular Collider Conceptual Design Report Volume 4
- Author
- Abada A
- Abbrescia M
- AbdusSalam SS
- Abdyukhanov I
- Abelleira Fernandez J
- Abramov A
- Aburaia M
- Acar AO
- Adzic PR
- Agrawal P
- Aguilar-Saavedra JA
- Aguilera-Verdugo JJ
- Aiba M
- Aichinger I
- Aielli G
- Akay A
- Akhundov A
- Aksakal H
- Albacete JL
- Albergo S
- Alekou A
- Aleksa M
- Aleksan R
- Alemany Fernandez RM
- Alexahin Y
- Alia RG
- Alioli S
- Alipour Tehrani N
- Allanach BC
- Allport PP
- Altinli M
- Altmannshofer W
- Ambrosio G
- Amorim D
- Amstutz O
- Anderlini L
- Andreazza A
- Andreini M
- Andriatis A
- Andris C
- Andronic A
- Angelucci M
- Antinori F
- Antipov SA
- Antonelli M
- Antonello M
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- Antusch S
- Anulli F
- Apolinario L
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- Apollonio A
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- Arbuzov A
- Arduini G
- Ari V
- Arias S
- Armesto N
- Arnaldi R
- Arsenyev SA
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- Asai S
- Aslanides E
- Assmann RW
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- Auchmann B
- Audurier A
- Aull S
- Aumon S
- Aune S
- Avino F
- Avrillaud G
- Aydin G
- Azatov A
- Azuelos G
- Azzi P
- Azzolini O
- Azzurri P
- Bacchetta N
- Bacchiocchi E
- Bachacou H
- Baek YW
- Baglin V
- Bai Y
- Baird S
- Baker MJ
- Baldwin MJ
- Ball AH
- Ballarino A
- Banerjee S
- Barber DP
- Barducci D
- Barjhoux P
- Barna D
- Barnafoldi GG
- Barnes MJ
- Barr A
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- Barreiro Guimaraes da Costa J
- Bartmann W
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- Bastianin A
- Baudouy B
- Bauer F
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- Baumgartner T
- Bautista-Guzman I
- Bayindir C
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- Bedeschi F
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- de Vivie de Regie JB
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- Honorato CG
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- Jimenez JM
- Jones MA
- Jones OR
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- Jung S
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- Kartal S
- Karyukhin A
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- Katharina Behr J
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- Publication venue
- SPRINGER HEIDELBERG
- Publication date
- 01/07/2019
- Field of study
Get PDFIn response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC study covered an energy-frontier hadron collider (FCC-hh), a highest-luminosity high-energy lepton collider (FCC-ee), the corresponding 100 km tunnel infrastructure, as well as the physics opportunities of these two colliders, and a high-energy LHC, based on FCC-hh technology. This document constitutes the third volume of the FCC Conceptual Design Report, devoted to the hadron collider FCC-hh. It summarizes the FCC-hh physics discovery opportunities, presents the FCC-hh accelerator design, performance reach, and staged operation plan, discusses the underlying technologies, the civil engineering and technical infrastructure, and also sketches a possible implementation. Combining ingredients from the Large Hadron Collider (LHC), the high-luminosity LHC upgrade and adding novel technologies and approaches, the FCC-hh design aims at significantly extending the energy frontier to 100 TeV. Its unprecedented centre-of-mass collision energy will make the FCC-hh a unique instrument to explore physics beyond the Standard Model, offering great direct sensitivity to new physics and discoveries
FCC-hh: The Hadron Collider: Future Circular Collider Conceptual Design Report Volume 3
- Author
- Abada A
- Abbrescia M
- AbdusSalam SS
- Abdyukhanov I
- Abelleira Fernandez J
- Abramov A
- Aburaia M
- Acar AO
- Adzic PR
- Agrawal P
- Aguilar-Saavedra JA
- Aguilera-Verdugo JJ
- Aiba M
- Aichinger I
- Aielli G
- Akay A
- Akhundov A
- Aksakal H
- Albacete JL
- Albergo S
- Alekou A
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- Aleksan R
- Alemany Fernandez RM
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 18/12/2018
- Field of study
Get PDFIn response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC study covered an energy-frontier hadron collider (FCC-hh), a highest-luminosity high-energy lepton collider (FCC-ee), the corresponding 100 km tunnel infrastructure, as well as the physics opportunities of these two colliders, and a high-energy LHC, based on FCC-hh technology. This document constitutes the third volume of the FCC Conceptual Design Report, devoted to the hadron collider FCC-hh. It summarizes the FCC-hh physics discovery opportunities, presents the FCC-hh accelerator design, performance reach, and staged operation plan, discusses the underlying technologies, the civil engineering and technical infrastructure, and also sketches a possible implementation. Combining ingredients from the Large Hadron Collider (LHC), the high-luminosity LHC upgrade and adding novel technologies and approaches, the FCC-hh design aims at significantly extending the energy frontier to 100 TeV. Its unprecedented centre of-mass collision energy will make the FCC-hh a unique instrument to explore physics beyond the Standard Model, offering great direct sensitivity to new physics and discoveries
HE-LHC: The High-Energy Large Hadron Collider
- Author
- Abada A
- Abbrescia M
- AbdusSalam SS
- Abdyukhanov I
- Abelleira Fernandez J
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 18/12/2018
- Field of study
Get PDFIn response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC study covered an energy-frontier hadron collider (FCC-hh), a highest-luminosity high-energy lepton collider (FCC-ee), the corresponding 100 km tunnel infrastructure, as well as the physics opportunities of these two colliders, and a high-energy LHC, based on FCC-hh technology. This document constitutes the third volume of the FCC Conceptual Design Report, devoted to the hadron collider FCC-hh. It summarizes the FCC-hh physics discovery opportunities, presents the FCC-hh accelerator design, performance reach, and staged operation plan, discusses the underlying technologies, the civil engineering and technical infrastructure, and also sketches a possible implementation. Combining ingredients from the Large Hadron Collider (LHC), the high-luminosity LHC upgrade and adding novel technologies and approaches, the FCC-hh design aims at significantly extending the energy frontier to 100 TeV. Its unprecedented centre-of-mass collision energy will make the FCC-hh a unique instrument to explore physics beyond the Standard Model, offering great direct sensitivity to new physics and discoveries
FCC-hh: The Hadron Collider: Future Circular Collider Conceptual Design Report Volume 3
- Author
- Abada A
- Abbrescia M
- AbdusSalam SS
- Abdyukhanov I
- Abelleira Fernandez J
- Abramov A
- Aburaia M
- Acar AO
- Adzic PR
- Agrawal P
- Aguilar-Saavedra JA
- Aguilera-Verdugo JJ
- Aiba M
- Aichinger I
- Aielli G
- Akay A
- Akhundov A
- Aksakal H
- Albacete JL
- Albergo S
- Alekou A
- Aleksa M
- Aleksan R
- Alemany Fernandez RM
- Alexahin Y
- Alia RG
- Alioli S
- Alipour Tehrani N
- Allanach BC
- Allport PP
- Altinli M
- Altmannshofer W
- Ambrosio G
- Amorim D
- Amstutz O
- Anderlini L
- Andreazza A
- Andreini M
- Andriatis A
- Andris C
- Andronic A
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- Antipov SA
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- Zeiler P
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- Zhang C
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- Zhong Y-M
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- Zurita J
- Publication venue
- SPRINGER HEIDELBERG
- Publication date
- 01/07/2019
- Field of study
Get PDFIn response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC study covered an energy-frontier hadron collider (FCC-hh), a highest-luminosity high-energy lepton collider (FCC-ee), the corresponding 100 km tunnel infrastructure, as well as the physics opportunities of these two colliders, and a high-energy LHC, based on FCC-hh technology. This document constitutes the third volume of the FCC Conceptual Design Report, devoted to the hadron collider FCC-hh. It summarizes the FCC-hh physics discovery opportunities, presents the FCC-hh accelerator design, performance reach, and staged operation plan, discusses the underlying technologies, the civil engineering and technical infrastructure, and also sketches a possible implementation. Combining ingredients from the Large Hadron Collider (LHC), the high-luminosity LHC upgrade and adding novel technologies and approaches, the FCC-hh design aims at significantly extending the energy frontier to 100 TeV. Its unprecedented centre of-mass collision energy will make the FCC-hh a unique instrument to explore physics beyond the Standard Model, offering great direct sensitivity to new physics and discoveries
Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures
- Author
- Adams J.D. (John D.)
- Agel J. (Julie)
- Ahn H. (Henry)
- Ahn J. (Jaimo)
- Albers G.H.R. (G.H. Robert)
- Alexander D. (David)
- Alosky R. (Rachel)
- Amirault J.D. (J. David)
- Amundsen A. (Asgeir)
- Anand S. (Sanjeev)
- Anderson C.G. (Christopher G.)
- Anderson L.K. (Linda K.)
- Anderson S.A. (Sarah A.)
- Apostle K. (Kelly)
- Archdeacon M. (Michael)
- Arora V. (Vinod)
- Aurang K. (Kamran)
- Avram V. (Victoria)
- Axelrod T. (Terry)
- Baele J. (Joseph)
- Baker J.K. (Janell K.)
- Bannister E.R. (Evan R.)
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- Ganguly U. (Utsav)
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- Gervais T. (Trevor)
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- Go P.M.N.Y.M. (Peter M.N.Y.M.)
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- Goslings J.C. (Carel)
- Govaert L. (Lonneke)
- Graaf E.J.R. (Eelco) de
- Groenendijk R.P.R. (Richard)
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- Gruen G. (Gary)
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- Gurich R.W. (Richard W.)
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- Hak D. (David)
- Hall J.A. (Jeremy A.)
- Halliday B. (Brett)
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- Hampton L. (Lynne)
- Hanusch B.C. (Birgit C.)
- Harrison M. (Mark)
- Hart C.P. (Cor P.) van der
- Hartog D. (Dennis) den
- Hasselund S. (Sondre)
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- Haverlag R. (Robert)
- Heels-Ansdell D. (Diane)
- Heetveld M.J. (Martin J.)
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- Henderson C. (Corey)
- Henderson E.R. (Eric R.)
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- Hess S. (Shelley)
- Hewitt M. (Michael)
- Hidy J.T. (Jennifer T.)
- Hileman B. (Barbara)
- Hill A.D. (Austin D.)
- Hjorthaug G. (Geir)
- Hoffman J.M. (Jodi M.)
- Hoffman W.H. (W. H.)
- Hollenbeck S.M. (Steven M.)
- Holt M. (Michael)
- Hoogendoorn J. (Jochem)
- Horan A.D. (Annamarie D.)
- Horner G. (Gillian)
- Horwitz D. (Daniel)
- Hoseth T.M. (Tor Magne)
- Howells F. (Fiona)
- Hsu J.R. (Joseph R.)
- Huff R.B. (Roger B.)
- Hull P. (Peter)
- Humphrey C.A. (Catherine A.)
- Hurley M. (Meghan)
- Ianssen T. (Torben)
- Inman D. (Dominic)
- Iorio R. (Richard)
- Irrgang J. (James)
- Jackson L.T. (Lyle T.)
- Jain A. (Arvind)
- Jain N. (Neeraj)
- Jenkins M. (Mark)
- Jenkinson R. (Richard)
- Jennings A. (Andrew)
- Jeray K.J. (Kyle J.)
- Johnson G. (Garth)
- Johnston D. (David)
- Johnston K. (Kelly)
- Jomaas G. (Geir)
- Jones C.B. (Clifford B.)
- Jones V. (Vicki)
- Josaputra H.A. (Hong A.)
- Kain M.S.H. (Michael S.H.)
- Kampen A. (A.) van
- Karges D.E. (David E.)
- Karlsten A. (Anders)
- Karsten T.M. (Thomas)
- Kates S. (Stephen)
- Keeve J.P. (Jonathan P.)
- Keller P. (Paul)
- Ketz J.P. (John P.)
- Khan F. (Farah)
- Khan R.M. (Ryan M.)
- Khanna A. (Angshuman)
- Kibsgård T. (Thomas)
- Kile E. (Evelyn)
- Kingwell S.P. (Stephen P.)
- Knobe M. (Matthias)
- Koppert C.L. (Cees L.)
- Korley R. (Robert)
- Kottam L. (Lucksy)
- Kreder H. (Hans)
- Kregor P. (Philip)
- Kruse K.K. (Kevin K.)
- Kuiken H. (Hans)
- Kunz M. (Monica)
- Lackey W.G. (Wesley G.)
- Lafferty P.M. (Paul M.)
- Lambert S. (Sue)
- Langan J.W. (Justin W.)
- Laughlin R. (Richard)
- Lawendy A.-R. (Abdel-Rahman)
- Lawson D. (Deanna)
- Le T. (Toan)
- Lee J. (Julia)
- Leenen L.P.H.
- Leffler L.C. (Lauren C.)
- Leighton R. (Ross)
- Lemke H.M. (H. Michael)
- Lewis C.G. (Courtland G.)
- Lewis S. (Sophie)
- Li D. (Doug)
- Li M. (Mengnai)
- Lieberman S. (Shane)
- Liem R. (Ronald)
- Lieshout E.M.M. (Esther) van
- Liew A. (Allen)
- Liew S. (Susan)
- Lindenbaum S. (Stephen)
- Linehan C. (Colleen)
- Lobo M.J. (Margaret J.)
- Logishetty R. (Rajanikanth)
- Lona T. (Tarjei)
- Lorenzo M. (Melissa)
- Love D. (David)
- Luther A. (Arlene)
- Ly T.V. (Thuan V.)
- Lyle L. (Lindsey)
- MacDonald S. (Shelley)
- MacLeod M. (Mark)
- Maddock D. (Deborah)
- Marcantonio A.J. (Andrew J.)
- Marston S.B. (Scott B.)
- Mauffrey C. (Cyril)
- May J. (Jedediah)
- McBeth J.C. (Jessica Cooper)
- McCormack R. (Robert)
- McDonald M.D. (Michael D.)
- McIntyre A.W. (Allison W.)
- McKay P. (Paula)
- McKee M.D. (Michael D.)
- McKercher R. (Ross)
- Mehta S. (Samir)
- Meijer J. (Joost)
- Meylaerts S.A.G. (Sven)
- Miller R. (Russell)
- Miller T.J. (Timothy J.)
- Mills K. (Kelli)
- Milner K. (Katrine)
- Mishra V. (Vimlesh)
- Mitchell K. (Khalis)
- Moatshe G. (Gilbert)
- Moaveni A. (Ash)
- Molund M. (Marius)
- Monica J.T. (James T.)
- Moola F. (Farhad)
- Moon K. (Karyn)
- Moon R. (Raely)
- Moore M.M. (Molly M.)
- Mullis B. (Brian)
- Murdoch Z. (Zoe)
- Murnaghan J. (John)
- Murphy R.L. (R. Lee)
- Murtha Y.M. (Yvonne M.)
- Müller O. (Oliver)
- Nam D. (Diane)
- Nanda R. (Rajesh)
- Nanney T. (Tracy)
- Napierala M. (Matthew)
- Nastoff L.A. (Lauren A.)
- Naumetz V. (V.)
- Nauth A. (Aaron)
- Newman H. (Heike)
- Nicolaisen T. (Tor)
- Nies F. (Frank) de
- Nilsen F. (Fredrik)
- Noble K. (Krista)
- Nousiainen M. (Markku)
- O'Malley L.K. (Lawrence K.)
- O'Neil J. (Joseph)
- Oatt A. (Amber)
- Obremskey W. (William)
- Olakkengil D.J. (Davy J)
- Oliver T.M. (Todd M.)
- Oprel P.P. (Pim)
- Out N.J.M. (Nico J.M.)
- Oxner W. (William)
- Pace T.B. (Thomas B.)
- Palla N. (Naveen)
- Pape H.-C. (Hans-Christoph)
- Papp S. (Steve)
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- Patka P. (Peter)
- Payton K. (Krystal)
- Pecorella K. (Kaili)
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- Peters M.E. (Melissa E.)
- Peters R. (Rolf)
- Peterson B. (Brett)
- Pfeifer R. (Roman)
- Pilling L. (Lindsey)
- Pincus P. (Paul)
- Pirpiris M. (Marinis)
- Poelhekke L.M.S.J.
- Pol C. (Carmen) van der
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- Poolman R.W. (Rudolf)
- Porter S.E. (Scott E.)
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- Powell J. (James)
- Prasad A.S. (Amal Shankar)
- Prayson M.J. (Michael J.)
- Price D.M. (Dustin M.)
- Probe R. (Robert)
- Puloski S. (Shannon)
- Rai A. (Anil)
- Rai B.S. (B. Sachidananda)
- Rai K. (Kamal)
- Rajakumar J. (Janakiraman)
- Rangan A. (Amar)
- Reardon G. (Gerald)
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- Reeves C. (Christina)
- Rhemrev S. (Steven)
- Richards J.E. (Justin E.)
- Richardson C.G. (C. Glen)
- Richardson M. (Martin)
- Rieser G.R. (Geoffrey Ryan)
- Riet M. (Martijne) van 't
- Rijbroek B. (Bram)
- Rijcke P.A.R. (Piet)
- Rijna H.
- Ringler J.R. (James R.)
- Ritchie E.D. (Ewan D.)
- Robbins K. (Kristin)
- Roffey D.M. (Darren M.)
- Romero A.W. (Amanda W.)
- Roper E. (Elizabeth)
- Rose G. (Glynis)
- Roukema G.R. (Gert)
- Rubino L.J. (L. Joseph)
- Russ M. (Matthias)
- Rutherford T. (Tori)
- Rydinge J. (Jonas)
- Sage C. (Claire)
- Sagebien C.A. (Carlos A.)
- Sanders D. (David)
- Sanghavi A. (Amir)
- Schaller T.M. (Thomas M.)
- Scheepers J.J. (Joris J.)
- Schemitsch E.H. (Emil H.)
- Schep N.W.L. (Niels)
- Schmidt A.H. (Andrew H.)
- Schreurs B. (Bart)
- Schrickel T. (Tyson)
- Schwappach J. (John)
- Scott T. (Taryn)
- Scrabeck T. (Tyson)
- Segers M.J.M. (Michiel)
- Sems S.A. (Stephen A.)
- Seuffert P. (Patricia)
- Shaer J. (James)
- Sharma A. (Ateet)
- Sharma G. (Gaurav)
- Shell L.E. (Leslie E.)
- Shepard S. (Stephanie)
- Shively K. (Karl)
- Sietsema D.L. (Debra L.)
- Silva H. (Heather)
- Silvis R. (Rob)
- Simmermacher R.K.J.
- Simons M.P.
- Simunovic N. (Nicole)
- Singh S. (Sanjay)
- Siroen M.P.C. (Michiel P.C.)
- Siska P. (Peter)
- Slobogean G.P. (Gerard P.)
- Smedsrud M. (Morten)
- Smits A.B. (Anke B.)
- Snellen J.P. (Jaap P.)
- Snider R.G. (Rebecca G.)
- Specht L.M. (Lawrence M.)
- Sprag S. (Sheila)
- Sprague S. (Sheila)
- Stahel P. (Philip)
- Stassen L.P.S. (Laurents P.S.)
- Stephen D. (David)
- Stinner D. (Daniel)
- Stockmann H. (Heyn)
- Stone T. (Trevor)
- Stringfellow K. (Kenya)
- Strohecker K. (Kent)
- Stull P. (Philip)
- Stødle A. (Are)
- Subash ()
- Sullivan R.J. (Raymond J.)
- Sundaresh D.C. (D. C.)
- Swenson T.K. (Teresa K.)
- Swinton M. (Marilyn)
- Swiontkowski M.F. (Marc )
- Switzer J.A. (Julie A.)
- Tan E.C.T.H. (Edward C.T.H.)
- Tanksley J.A. (John A.)
- Tanner S.L. (Stephanie L.)
- Tannoury C. (Chadi)
- Tarkin I. (Ivan)
- Teasdall R.J. (Robert J.)
- Tetsworth K. (Kevin)
- Tetteroo G.W.M. (Geert)
- Thabane L. (Lehana)
- Theunissen E.B.M. (Evert B.M.)
- Tieszer C. (Christina)
- Tilzey J.F. (John F.)
- Ton L. (Lu)
- Torchia M.E. (Michael E.)
- Tornetta III P. (Paul)
- Torres E.T. (Erick T.)
- Trask K. (Kelly)
- Trenholm J.A. (J. Andrew)
- Trivedi M. (Mittal)
- Trommer A. (Axel)
- Turckan K. (Kahn)
- Tyagi V. (Vivek)
- Tynan M.C. (Martin C.)
- Ugland S. (Stein)
- Vallier H.A. (Heather A.)
- Van Der Brand I. (Igor)
- Van Der Hoeven H. (Henk)
- Van Egmond T. (Teun)
- Van Gaalen S.M. (Steven M.)
- Van Mulken J. (Jeroen)
- Van Vugt A.B. (Arie B.)
- Vang S. (Sandy)
- Verhagen R. (Ronald)
- Verhoeven B. (Bart)
- Verhofstad M.H.J. (Michiel)
- Vermeulen E.G.J. (Erik G.J.)
- Vesterhus E.B. (Elise Berg)
- Vicente M.R. (Milena R.)
- Vis H.M. (Harm) van der
- Viskontas D. (Darius)
- Visser G.A. (Gijs A.)
- Viveiros H. (Helena)
- Vogt M. (Michelle)
- Vries A.C. (Alexander) de
- Vries M.R. (Mark) de
- Vuylsteke R. (Ronald)
- Wadey V. (Veronica)
- Waes O.J.F. (Oscar) van
- Wai E.K. (Eugene K.)
- Walker J.E. (Jane E.)
- Walter S.D. (Stephen D.)
- Wang O. (Otis)
- Ward A. (Angela)
- Watson D.J. (Dylan J.)
- Watson S.T. (Scott T.)
- Weber T. (Timothy)
- Weening B. (Brad)
- Weinerman S. (Stuart)
- Weingarten P. (Peter)
- Weinrauch P. (Patrick)
- Wessel R.N. (Ronald N.)
- Wessem K.J.P. van
- Westberg J.R. (Jerald R.)
- Whatley E. (Erica)
- Whelan D.B. (Daniel B.)
- Wild L.M. (Lisa M.)
- Wille J.C. (Jan)
- Willems W.J. (Jaap)
- Wittich P. (Philippe)
- Wong I. (Ivan)
- Wood G. (Gavin)
- Worman R. (Ripley)
- Wright D.M. (David M.)
- Wyrick J. (John)
- Yach J. (Jeff)
- Yadav V. (Vineet)
- Yang S. (Steven)
- Yee A. (Albert)
- Yen D. (David)
- Yu M. (Michelle)
- Zalzal P. (Paul)
- Zamorano D.P. (David P.)
- Zellar A. (Abby)
- Zhou Q. (Qi)
- Zielinski S.M. (Stephanie)
- Zijl J.A.C. (Jacco A.C.)
- Zohman G. (Gary)
- Zomar M. (Mauri)
- Zurcher A.W. (Arthur W.)
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/05/2018
- Field of study
Get PDFBackground: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo
