849 research outputs found
Humanized Mice Recapitulate Key Features of HIV-1 Infection: A Novel Concept Using Long-Acting Anti-Retroviral Drugs for Treating HIV-1
- Author
- A Manrique
- AM Vandamme
- Anja Van Cauwenberge
- Annette Audigé
- Bart Stoops
- BK Berges
- C Bazzoli
- C Christopherson
- CA Stoddart
- CD Miller
- CF Althaus
- Cheryl A. Stoddart
- CJ Cohen
- CV Fletcher
- Daniel Boden
- Duo Li
- DV Cordery
- E Traggiai
- Erika Schlaepfer
- G van't Klooster
- GE Chittick
- Guenter Kraus
- Gustavo Gers-Huber
- H Goldstein
- JL Heeney
- JM McCune
- JM Molina
- K Sango
- Katie Amssoms
- L Baert
- L Zhang
- LD Shultz
- M Ito
- Marc Nischang
- Mary-Aude Rochat
- MD Marsden
- ML Bonyhadi
- P Kaiser
- PW Denton
- Q Jiang
- R Camacho
- R Namikawa
- R Schrijvers
- Roberto F. Speck
- Roger Sutmuller
- RP Walensky
- S Baenziger
- S Gorantla
- S Reagan-Shaw
- S Taylor
- S Watanabe
- S Watanabe
- SK Choudhary
- SK Choudhary
- Stefan Baenziger
- Stephan Regenass
- TW Chun
- Ursula Hofer
- YV T. Pattery
- Z Fox
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
BACKGROUND: Humanized mice generate a lymphoid system of human origin subsequent to transplantation of human CD34+ cells and thus are highly susceptible to HIV infection. Here we examined the efficacy of antiretroviral treatment (ART) when added to food pellets, and of long-acting (LA) antiretroviral compounds, either as monotherapy or in combination. These studies shall be inspiring for establishing a gold standard of ART, which is easy to administer and well supported by the mice, and for subsequent studies such as latency. Furthermore, they should disclose whether viral breakthrough and emergence of resistance occurs similar as in HIV-infected patients when ART is insufficient.
METHODS/PRINCIPAL FINDINGS: NOD/shi-scid/Îł(c)null (NOG) mice were used in all experimentations. We first performed pharmacokinetic studies of the drugs used, either added to food pellets (AZT, TDF, 3TC, RTV) or in a LA formulation that permitted once weekly subcutaneous administration (TMC278: non-nucleoside reverse transcriptase inhibitor, TMC181: protease inhibitor). A combination of 3TC, TDF and TMC278-LA or 3TC, TDF, TMC278-LA and TMC181-LA suppressed the viral load to undetectable levels in 15/19 (79%) and 14/14 (100%) mice, respectively. In successfully treated mice, subsequent monotherapy with TMC278-LA resulted in viral breakthrough; in contrast, the two LA compounds together prevented viral breakthrough. Resistance mutations matched the mutations most commonly observed in HIV patients failing therapy. Importantly, viral rebound after interruption of ART, presence of HIV DNA in successfully treated mice and in vitro reactivation of early HIV transcripts point to an existing latent HIV reservoir.
CONCLUSIONS/SIGNIFICANCE: This report is a unique description of multiple aspects of HIV infection in humanized mice that comprised efficacy testing of various treatment regimens, including LA compounds, resistance mutation analysis as well as viral rebound after treatment interruption. Humanized mice will be highly valuable for exploring the antiviral potency of new compounds or compounds targeting the latent HIV reservoir
Impacts of the Tropical Pacific/Indian Oceans on the Seasonal Cycle of the West African Monsoon
- Author
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abdulsalam Abdulla
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adiguzel Aytul
- Adler Volker
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Akin Ilina Vasileva
- Albajar Carmen
- Albayrak Elif Asli
- Albergo Sebastiano
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- AldĂĄ JĂșnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
- Alimena Juliette
- Alverson George
- Alves Gilvan
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anderson Ian
- Anderson Jacob
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Androsov Konstantin
- Antonelli Louis
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Arora Sanjay
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asin Ivan
- Askew Andrew
- Aslanoglou Xenofon
- Assran Yasser
- Ata Metin
- Attikis Alexandros
- Aubin Alexandre
- Auffray Etiennette
- Autermann Christian Tobias
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Baarmand Marc M.
- Baber Mark
- Bacchetta Nicola
- Bachmair Felix
- Bachtis Michail
- Baden Drew
- Baffioni Stephanie
- Bagliesi Giuseppe
- Baillon Paul
- Bainbridge Robert
- Bakhshiansohi Hamed
- Bakirci Mustafa Numan
- Ball Austin
- Ban Yong
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Barbieri Richard
- Bargassa Pedrame
- Barge Derek
- Baringer Philip
- Barker Anthony
- Barnes Virgil E.
- Barnett Bruce Arnold
- Barney David
- Barone Luciano
- Barth Christian
- Bartosik Nazar
- Basegmez Suzan
- Battilana Carlo
- Bauerdick Lothar A. T.
- Baumgartel Darin
- Baus Colin
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beaupere Nicolas
- Beernaert Kelly
- Behnamian Hadi
- Behr Joerg
- Behrens Ulf
- BeirĂŁo Da Cruz E Silva CristĂłvĂŁo
- Belforte Stefano
- Beliy Nikita
- Belknap Donald
- Bell Alan James
- Bell Ken W.
- Bellan Riccardo
- Belloni Alberto
- Beluffi Camille
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Bencze Gyorgy
- Bendavid Joshua
- Benedetti Daniele
- Benelli Gabriele
- Benhabib Lamia
- Beni Noemi
- Benitez Jose F.
- Benucci Leonardo
- Benussi Luigi
- Benvenuti Alberto
- Beranek Sarah
- Beretvas Andrew
- Bergauer Thomas
- Berger Joram
- Beri Suman Bala
- Bernardes Cesar Augusto
- Bernardini Jacopo
- Bernet Colin
- Berry Douglas
- Berry Edmund
- Berryhill Jeffrey
- Bertl Willi
- Besancon Marc
- Betchart Burton
- Bethani Agni
- Betts Russell Richard
- Bhardwaj Ashutosh
- Bhat Pushpalatha C.
- Bhatnagar Vipin
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bhawandeep Bhawandeep
- Bhowmik Sandeep
- Bialkowska Helena
- Bian Jian-Guo
- Bianchini Lorenzo
- Bianco Stefano
- Biasini Maurizio
- Biino Cristina
- Bilei Gian Mario
- Bilin Bugra
- Bilki Burak
- Bilmis Selcuk
- Bisello Dario
- Bitioukov Sergei
- Blekman Freya
- Blobel Volker
- Bloch Daniel
- Bloch Philippe
- Bloom Kenneth
- Bluj Michal
- Blumenfeld Barry
- Blyweert Stijn
- Boccali Tommaso
- Bocci Andrea
- Bochenek Joseph
- Bodek Arie
- Bodlak Martin
- Boimska Bozena
- Bolla Gino
- Bolognesi Sara
- Bonacorsi Daniele
- Bonato Alessio
- Bondu Olivier
- Bontenackels Michael
- Boos Edouard
- Bornheim Adolf
- Borras Kerstin
- Bortignon Pierluigi
- Bortoletto Daniela
- Bose Suvadeep
- Bose Tulika
- Botta Cristina
- Boudoul Gaelle
- Bouhali Othmane
- Bourilkov Dimitri
- Boutle Sarah
- Bouvier Elvire
- Bradmiller-Feld John
- Braibant-Giacomelli Sylvie
- Branca Antonio
- Branson James G.
- Breedon Richard
- Breto Guillermo
- Breuker Horst
- Brew Christopher
- Brigliadori Luca
- Brigljevic Vuko
- Brinkerhoff Andrew
- Brinson Jessica
- Brito Lucas
- Broccolo Giuseppe
- Brochero Cifuentes Javier Andres
- Brochet SĂ©bastien
- Brodski Michael
- Brom Jean-Marie
- Brona Grzegorz
- Brooke James John
- Brown Robert M.
- Brownson Eric
- Brun Hugues
- Bruner Christopher
- Bruno Giacomo
- Buchmann Marco-Andrea
- Buchmuller Oliver
- Bucinskaite Inga
- Bunichev Viacheslav
- Bunin Pavel
- Bunkowski Karol
- Bunn Julian
- Buontempo Salvatore
- Burgmeier Armin
- Burkett Kevin
- Burt Kira
- Burton Darren
- Busson Philippe
- Busza Wit
- Butler Joel Nathan
- Butler Philip H.
- Butz Erik
- Bylsma Ben
- BĂ€ni Lukas
- Böser Christian
- Cabrera Andrés
- Cabrillo Iban Jose
- Caebergs Thierry
- Caillol CĂ©cile
- Cakir Altan
- Calabria Cesare
- Calamba Aristotle
- Calderon De La Barca Sanchez Manuel
- Calderon Alicia
- Cali Ivan Amos
- Calligaris Luigi
- Calvert Brian
- Calvo Enrique
- Campagnari Claudio
- Campanini Renato
- Campbell Alan
- Camporesi Tiziano
- Candelise Vieri
- Canelli Maria Florencia
- Cankocak Kerem
- Capiluppi Paolo
- Cappello Gigi
- Cardaci Marco
- Carlin Roberto
- Carlsmith Duncan
- Carlson Benjamin
- Carrillo Montoya Camilo Andres
- Carrillo Moreno Salvador
- Cartiglia Nicolo
- Carvalho Wagner
- Carver Matthew
- Casal Bruno
- Casarsa Massimo
- Casasso Stefano
- Casimiro Linares Edgar
- Castaldi Rino
- Castaneda Hernandez Alfredo
- Castello Roberto
- Castilla-Valdez Heriberto
- Castro Andrea
- Caudron Adrien
- Cavallari Francesca
- Cavallo Francesca Romana
- Cavallo Nicola
- Cavanaugh Richard
- Ceard Ludivine
- Centis Vignali Matteo
- Cepeda Maria
- Cerati Giuseppe Benedetto
- Cerci Salim
- Cerminara Gianluca
- Cerrada Marcos
- Chabert Eric Christian
- Chakaberia Irakli
- Chamizo Llatas Maria
- Chan Kwok Ming
- Chan Matthew
- Chang Paoti
- Chang Sunghyun
- Chang You-Hao
- Chang Yu-Wei
- Chanon Nicolas
- Chao Yuan
- Chaparro Sierra Luisa Fernanda
- Charaf Otman
- Charlot Claude
- Chasco Matthew
- Chasserat Julien
- Chatterjee Avishek
- Chatterjee Kalyanmoy
- Chatterjee Rajdeep Mohan
- Chauhan Sushil
- Chaves Jorge
- Checchia Paolo
- Chen Guo-Ming
- Chen He-Sheng
- Chen Kai-Feng
- Chen Kuan-Hsin
- Chen Mingshui
- Chen Po-Hsun
- Chen Yi
- Cheng Tongguang
- Cherepanov Vladimir
- Chertok Maxwell
- Cheung Harry
- Chhibra Simranjit Singh
- Chierici Roberto
- Chinellato Jose
- Chiochia Vincenzo
- Chiorboli Massimiliano
- Chlebana Frank
- Choi Minkyoo
- Choi Suyong
- Choi Young Kyu
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C.
- Choudhury Somnath
- Christopher Grant
- Chu Jennifer
- Chwalek Thorsten
- Ciangottini Diego
- Ciesielski Robert
- Cihangir Selcuk
- Cimmino Anna
- Ciocci Maria Agnese
- Cittolin Sergio
- Ciulli Vitaliano
- Civinini Carlo
- Claes Daniel R.
- Clare Robert
- Clarida Warren
- Clarke Christopher
- Clement Emyr
- Clerbaux Barbara
- CMS Collaboration
- Cockerill David J. A.
- Codispoti Giuseppe
- Colafranceschi Stefano
- Colaleo Anna
- Cole Joanne
- Colino Nicanor
- Collard Caroline
- Colling David
- Contardo Didier
- Conte Eric
- Contreras-Campana Christian
- Contreras-Campana Emmanuel
- Conway John
- Conway Rylan
- Cooper Seth
- Cornelis Tom
- Correa Martins Junior Marcos
- Cossutti Fabio
- Costa Marco
- Costa Salvatore
- Costantini Silvia
- Costanza Francesco
- Couderc Fabrice
- Coughlan John A.
- Cousins Robert
- Covarelli Roberto
- Cowden Christopher
- Cox Bradley
- Cox Peter Timothy
- Creanza Donato
- Cripps Nicholas
- Crucy Shannon
- Cuevas Javier
- Cuffiani Marco
- Cumalat John Perry
- Curry David
- Cussans David
- CustĂłdio Analu
- Cutts David
- Cwiok Mikolaj
- Czellar Sandor
- D'Agnolo Raffaele Tito
- D'Alessandro Raffaello
- D'Alfonso Mariarosaria
- D'Enterria David
- D'Hondt Jorgen
- D'imperio Giulia
- Da Silveira Gustavo Gil
- Dabrowski Anne
- Daci Nadir
- Dahmes Bryan
- Dahms Torsten
- Dalchenko Mykhailo
- Dall'Osso Martino
- Dallavalle Gaetano-Marco
- Damgov Jordan
- Danielson Thomas
- Das Souvik
- Daskalakis Georgios
- Dasu Sridhara
- Daubie Evelyne
- Dauncey Paul
- David Tinoco Mendes Andre
- Davies Gavin
- de Barbaro Pawel
- De Boer Wim
- De Cosa Annapaola
- De Filippis Nicola
- De Gruttola Michele
- De Guio Federico
- De Jesus Damiao Dilson
- De La Cruz Begona
- De La Cruz-Burelo Eduard
- De Lentdecker Gilles
- De Mattia Marco
- De Moraes Gregores Eduardo
- De Oliveira Martins Carley
- De Palma Mauro
- De Roeck Albert
- de TrocĂłniz Jorge F.
- De Visscher Simon
- De Wolf Eddi A.
- Degano Alessandro
- Deiters Konrad
- Dejardin Marc
- Del Re Daniele
- Del Rocio Vargas Trevino Andrea
- Delaere Christophe
- Delannoy Andrés G.
- Delgado Peris Antonio
- Dell'Orso Roberto
- Della Negra Michel
- Della Ricca Giuseppe
- Demaria Natale
- Demina Regina
- Demiragli Zeynep
- Demortier Luc
- Denegri Daniel
- Depasse Pierre
- Dermenev Alexander
- Descroix Alexis
- Dewanjee Ram Krishna
- Dhingra Nitish
- Di Giovanni Gian Piero
- Di Guida Salvatore
- Di Marco Emanuele
- Di Matteo Leonardo
- Diamond Brendan
- Diemoz Marcella
- Dierlamm Alexander
- Dietz Charles
- Dietz-Laursonn Erik
- Diez Pardos Carmen
- Dildick Sven
- Dilsiz Kamuran
- Dimitrov Anton
- Dinardo Mauro Emanuele
- Dishaw Adam
- Dissertori GĂŒnther
- Dittmann Jay
- Dittmar Michael
- Dittmer Susan
- Dobrzynski Ludwik
- Dobson Marc
- Dobur Didar
- Dodd Laura
- Dogra Sunil
- Dolen James
- Dolinska Ganna
- Dominguez Aaron
- Dominik Wojciech
- DomĂnguez VĂĄzquez Daniel
- Donato Silvio
- DonegĂ Mauro
- Dooling Samantha
- Dordevic Milos
- Dorigo Tommaso
- Dorland Tyler
- Dorney Brian
- Doroba Krzysztof
- Dos Reis Martins Thiago
- Dosselli Umberto
- Dozen Candan
- Draeger Arne-Rasmus
- Dragicevic Marko
- Dragoiu Cosmin
- Dremin Igor
- Driga Olga
- Drozdetskiy Alexey
- Du Pree Tristan
- Du Ran
- Duarte Campderros Jordi
- Duarte Javier
- Dubinin Mikhail
- Duchardt Deborah
- Dudero Phillip Russell
- Dudko Lev
- Dugad Shashikant
- Duggan Daniel
- Dumanoglu Isa
- Dunne Patrick
- Dupont-Sagorin Niels
- Duric Senka
- Durkin Lloyd Stanley
- Dutta Dipanwita
- Dutta Suchandra
- Dutta Valentina
- DĂŒnser Marc
- Eckerlin Guenter
- Ecklund Karl Matthew
- Eckstein Doris
- Edelhoff Matthias
- Eerola Paula
- Eggert Nicholas
- Eichhorn Thomas
- Ekmedzic Marko
- El Mamouni Houmani
- Eller Philipp
- Elliott-Peisert Anna
- Ellison John Anthony
- Ellithi Kamel Ali
- Elmer Peter
- Elvira Victor Daniel
- Eno Sarah Catherine
- Epshteyn Vladimir
- Erbacher Robin
- Erdmann Martin
- Erdmann Wolfram
- Erdogan Yusuf
- Erfle Joachim
- Erö Janos
- Escalante Del Valle Alberto
- Eshaq Yossof
- Eskut Eda
- Etesami Seyed Mohsen
- Eusebi Ricardo
- Evangelou Ioannis
- Evdokimov Olga
- Everaerts Pieter
- Fabbri Fabrizio
- Fabbri Franco
- Fabbro Bernard
- Fabozzi Francesco
- Faccioli Pietro
- Fagot Alexis
- Fahim Ali
- Fan Jiawei
- Fanfani Alessandra
- Fantasia Cory
- FanĂČ Livio
- Farrell Chris
- Fasanella Daniele
- Faulkner James
- Faure Jean-Louis
- Favaro Carlotta
- Favart Denis
- Favart Laurent
- Fay Jean
- Fedi Giacomo
- Fehling David
- Feindt Michael
- Felcini Marta
- Feld Lutz
- Ferapontov Alexey
- Ferbel Thomas
- Ferencek Dinko
- Ferguson Thomas
- Ferguson William
- Fernandez Bedoya Cristina
- Fernandez Menendez Javier
- Fernandez Marcos
- FernĂĄndez Ramos Juan Pablo
- Ferreira Parracho Pedro Guilherme
- Ferretti Roberta
- Ferri Federico
- Ferro Cristina
- Ferro Fabrizio
- Field Richard D.
- Filipovic Nicolas
- Finco Linda
- Finger Jr. Michael
- Finger Miroslav
- Fiore Luigi
- Fiorendi Sara
- Fiori Francesco
- Fischer Robert
- Fisher Matthew
- Fisk Ian
- Flacher Henning
- Flanagan Will
- Flix Jose
- Florent Alice
- Florez Carlos
- Flouris Giannis
- Flowers Kristen
- Flowers Sean
- Flucke Gero
- FlĂŒgge GĂŒnter
- Focardi Ettore
- Folgueras Santiago
- Fonseca De Souza Sandro
- Fontaine Jean-Charles
- Ford William T.
- Forthomme Laurent
- Foudas Costas
- Fouz Maria Cruz
- FoĂ Lorenzo
- Francis Brian
- Franco Sevilla Manuel
- Franzoni Giovanni
- Freeman Jim
- Frensch Felix
- Friedl Markus
- Friis Evan
- Frueboes Tomasz
- Fruehwirth Rudolf
- Fulcher Jonathan
- Funk Wolfgang
- Furic Ivan-Kresimir
- Futyan David
- Gabusi Michele
- Gadrat SĂ©bastien
- Gainer J.
- Galanti Mario
- Gallinaro Michele
- Gallo Elisabetta
- Gamsizkan Halil
- Ganguly Sanmay
- Ganjour Serguei
- Gao Yanyan
- Garabedian Alex
- Garay Garcia Jasone
- Garcia Guillaume
- Garcia-Abia Pablo
- Garcia-Bellido Aran
- Gardner Michael
- Garutti Erika
- Gary J. William
- Gascon Susan
- Gasparini Fabrizio
- Gasparini Ugo
- Gauthier Lucie
- Gavrilenko Mikhail
- Gavrilov Vladimir
- Gay Arnaud
- Gaz Alessandro
- Geenen Heiko
- Geffert Paul
- Geiser Achim
- Geisler Matthias
- Gelé Denis
- Genchev Vladimir
- Gennai Simone
- George Christopher
- Geralis Theodoros
- Gerber Cecilia Elena
- Gerosa Raffaele
- Gershtein Yuri
- Geurts Frank J. M.
- Ghete Vasile Mihai
- Ghezzi Alessio
- Ghosh Saranya
- Giacomelli Paolo
- Giakoumopoulou Viktoria Athina
- Giammanco Andrea
- Giassi Alessandro
- Giffels Manuel
- Gigi Dominique
- Gilbert Andrew
- Gill Karl
- Gilmore Jason
- Giordano Domenico
- Giordano Ferdinando
- Girgis Semiray
- Girone Maria
- Givernaud Alain
- Glege Frank
- Glushkov Ivan
- Gninenko Sergei
- Gobbo Benigno
- Godinovic Nikola
- Godshalk Andrew
- Goebel Kristin
- Goerlach Ulrich
- Goetzmann Christophe
- Goh Junghwan
- Gokbulut Gul
- Goldenzweig Pablo
- Goldouzian Reza
- Goldstein Joel
- Golf Frank
- Golovtsov Victor
- Golubev Nikolai
- Golutvin Igor
- Gomber Bhawna
- Gomez Ceballos Guillelmo
- Gomez Moreno Bernardo
- Gomez Gervasio
- Gomez Jaime
- Gomez Juan Pablo
- Goncharov Maxim
- Gonzalez Caballero Isidro
- Gonzalez Lopez Oscar
- Gonzalez Suarez Rebeca
- Gonzi Sandro
- Goodell Joseph
- Gorbunov Ilya
- Gori Valentina
- Gottschalk Erik
- Goulianos Konstantin
- Gouskos Loukas
- Gouzevitch Maxime
- Govoni Pietro
- Goy Lopez Silvia
- Gozzelino Andrea
- Grab Christoph
- Grandi Claudio
- Granier de Cassagnac Raphael
- Gras Philippe
- Gray Julia
- Gray Lindsey
- Gray Richard
- Graziano Alberto
- Grebenyuk Anastasia
- Green Dan
- Greene Senta
- Gribushin Andrey
- Grimes Mark
- Grippo Maria Teresa
- Gritsan Andrei
- Gronberg Jeffrey
- Grundler Ulysses
- Grunewald Martin
- GrĂŒnendahl Stefan
- Guchait Monoranjan
- Gude Alexander
- Guida Roberto
- Guiducci Luigi
- Guler Yalcin
- Gulhan Doga
- Gundacker Stefan
- Gunnellini Paolo
- Gupta Ruchi
- Gurpinar Emine
- Gurrola Alfredo
- Gurtu Atul
- Gutay Laszlo
- Guthoff Moritz
- Gutsche Oliver
- Gyun Dooyeon
- GĂłrski Maciej
- Görner Martin
- GĂŒlmez Erhan
- GĂŒth Andreas
- Haas Jeff
- Hadjiiska Roumyana
- Hadley Nicholas John
- Hagopian Sharon
- Hagopian Vasken
- Hahn Kristan Allan
- Haj Ahmad Wael
- Hajdu Csaba
- Halkiadakis Eva
- Hall Geoffrey
- Hall-Wilton Richard
- Haller Johannes
- Hamel de Monchenault Gautier
- Hammad Gregory Habib
- Hammer Josef
- Han Jiyeon
- Hanlon Jim
- Hansen Magnus
- Hanson Gail
- Hardenbrook Joshua
- Harder Kristian
- Hare Daryl
- Harel Amnon
- Harper Sam
- Harr Robert
- Harris Philip
- Harris Robert M.
- Hart Andrew
- Hartl Christian
- Hartmann Frank
- Hassan Qamar
- Hatakeyama Kenichi
- Hauk Johannes
- Hauser Jay
- Hauth Thomas
- Haytmyradov Maksat
- Heath Greg P.
- Heath Helen F.
- Hebbeker Thomas
- Hebda Philip
- Hegeman Jeroen
- Heidemann Carsten Andreas
- Heilman Jesse
- Heintz Ulrich
- Heister Arno
- Hempel Maria
- Henderson Conor
- Heracleous Natalie
- Heredia-de La Cruz Ivan
- Hernandez Jose M.
- Hernandez-Almada Alberto
- Herndon Matthew
- Hervé Alain
- Hewamanage Samantha
- Hidas Dean
- Hidas PĂ l
- Hildreth Michael
- Hill Christopher
- Hindrichs Otto
- Hinzmann Andreas Dominik
- Hirosky Robert
- Hirschauer James
- Hits Dmitry
- Hobson Peter R.
- Hoepfner Kerstin
- Hoffmann Malte
- Hofman David Jonathan
- Hohlmann Marcus
- Hollar Jonathan
- Holzner André
- Hong Byung-Sik
- Hooberman Benjamin
- Hoorani Hafeez R.
- Horisberger Roland
- Horvath Dezso
- Hos Ilknur
- Hoss Jan
- Hou George Wei-Shu
- Hreus Tomas
- Hrubec Josef
- Hu Zhen
- Hughes Richard
- Hugon Justin
- Husemann Ulrich
- HÀrkönen Jaakko
- Höhle Felix
- Höing Rebekka Sophie
- Hörmann Natascha
- Iaselli Giuseppe
- Iashvili Ia
- Iaydjiev Plamen
- Ignatenko Mikhail
- Iiyama Yutaro
- Iles Gregory
- Ille Bernard
- Incandela Joe
- Ingram Quentin
- Innocente Vincenzo
- Iorio Alberto Orso Maria
- Isildak Bora
- Ivanov Andrew
- Ivanov Yury
- Ivova Rikova Mirena
- Jacob Jeson
- Jafari Abideh
- Jain Sandhya
- Jain Shilpi
- Jandir Pawandeep
- Janot Patrick
- Janssen Xavier
- Jarry Patrick
- Jarvis Martyn
- Jeitler Manfred
- Jessop Colin
- Jez Pavel
- Jha Manoj
- Jiang Chun-Hua
- Jindariani Sergo
- Jo Mihee
- Johns Willard
- Johnson Kurtis F.
- Johnson Marvin
- Jones Matthew
- Jorda Clara
- Josa Maria Isabel
- Joshi Umesh
- Jung Hannes
- Jung Kurt
- Junkes Alexandra
- Juodagalvis Andrius
- Justus Christopher
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- Vorobiev Igor
- Vorobyev Alexey
- Vorobyev Andrey
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- Vuosalo Carl
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- Wagner-Kuhr Jeannine
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- Wang Dayong
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- Wang Zheng
- Wardle Nicholas
- Wayand Stefan
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- Weber Hendrik
- Weber Martin
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- Weiler Thomas
- Weinberg Marc
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- Weng Yao
- Werner Jeremy Scott
- West Christopher
- Wetzel James
- Whitbeck Andrew
- Whitmore Juliana
- Wickramage Nadeesha
- Wilbur Scott
- Wilken Rachel
- Wilkinson Richard
- Williams Thomas
- Wimpenny Stephen
- Winer Brian L.
- Winn Dave
- Winstrom Lucas
- Wissing Christoph
- Wittich Peter
- Wittmer Bruno
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- Wolf Roger
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- Wollny Heiner
- Womersley William John
- Won Steven
- Wood Darien
- Wood Jeffrey Scott
- Wood John
- Woodard Anna
- Woods Nathaniel
- Worm Steven
- Wright Douglas
- Wulsin Howard Wells
- Wulz Claudia-Elisabeth
- Wyslouch Bolek
- Wöhri Hermine Katharina
- WĂŒrthwein Frank
- Xiao Hong
- Xiao Meng
- Xie Si
- Xie Wei
- Xu Lingshan
- Xu Zijun
- Yagil Avraham
- Yalvac Metin
- Yang Fan
- Yang Mingming
- Yang Yong
- Yazgan Efe
- Yelton John
- Yetkin Taylan
- Yi Kai
- Yilmaz Yetkin
- Yohay Rachel
- Yoo Hwi Dong
- Yoo Jaehyeok
- York Andrew
- You Can
- Yu Intae
- Yu Shin-Shan
- Yumiceva Francisco
- Zabel James
- Zabi Alexandre
- Zablocki Jakub
- Zaganidis Nicolas
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zenoni Florian
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zeyrek Mehmet
- Zhang Jinzhong
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou Wei
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Zvada Marian
- Publication venue
- American Meteorological Society
- Publication date
- 01/08/2011
- Field of study
The current consensus is that drought has developed in the Sahel during the second half of the twentieth century as a result of remote effects of oceanic anomalies amplified by local landâatmosphere interactions. This paper focuses on the impacts of oceanic anomalies upon West African climate and specifically aims to identify those from SST anomalies in the Pacific/Indian Oceans during spring and summer seasons, when they were significant. Idealized sensitivity experiments are performed with four atmospheric general circulation models (AGCMs). The prescribed SST patterns used in the AGCMs are based on the leading mode of covariability between SST anomalies over the Pacific/Indian Oceans and summer rainfall over West Africa. The results show that such oceanic anomalies in the Pacific/Indian Ocean lead to a northward shift of an anomalous dry belt from the Gulf of Guinea to the Sahel as the season advances. In the Sahel, the magnitude of rainfall anomalies is comparable to that obtained by other authors using SST anomalies confined to the proximity of the Atlantic Ocean. The mechanism connecting the Pacific/Indian SST anomalies with West African rainfall has a strong seasonal cycle. In spring (May and June), anomalous subsidence develops over both the Maritime Continent and the equatorial Atlantic in response to the enhanced equatorial heating. Precipitation increases over continental West Africa in association with stronger zonal convergence of moisture. In addition, precipitation decreases over the Gulf of Guinea. During the monsoon peak (July and August), the SST anomalies move westward over the equatorial Pacific and the two regions where subsidence occurred earlier in the seasons merge over West Africa. The monsoon weakens and rainfall decreases over the Sahel, especially in August.Peer reviewe
Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC
- Author
- Acharya Shreyasi
- Adamova Dagmar
- Adolfsson Jonatan
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Al-turany Mohammad
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alfaro Molina Jose Ruben
- Ali Yasir
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altenkamper Lucas
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andreou Dimitra
- Andrews Harry Arthur
- Andronic Anton
- Anguelov Venelin
- Anson Christopher Daniel
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Arnaldi Roberta
- Arnold Oliver Werner
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
- Ball Markus
- Baral Rama Chandra
- Barbano Anastasia Maria
- Barbera Roberto
- Barile Francesco
- Barioglio Luca
- Barnafoldi Gergely Gabor
- Barnby Lee Stuart
- Bartalini Paolo
- Barth Klaus
- Bartsch Esther
- Bashir Butt Jamila
- Bastid Nicole
- Basu Sumit
- Batigne Guillaume
- Batyunya Boris
- Batzing Paul Christoph
- Bautista Guzman Irais
- Bazo Alba Jose Luis
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
- Bellini Francesca
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- Bellwied Rene
- Belyaev Vladimir
- Bencedi Gyula
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- Bercuci Alexandru
- Berdnikov Yaroslav
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- Bertens Redmer Alexander
- Berzano Dario
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- Blume Christoph
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- Boldizsar Laszlo
- Bombara Marek
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- Book Julian Heinz
- Borel Herve
- Borissov Alexander
- Borri Marcello
- Botta Elena
- Bourjau Christian
- Bratrud Lars
- Braun-munzinger Peter
- Bregant Marco
- Broker Theo Alexander
- Broz Michal
- Brucken Erik Jens
- Bruna Elena
- Bruno Giuseppe Eugenio
- Budnikov Dmitry
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- Bufalino Stefania
- Buhler Paul
- Buncic Predrag
- Busch Oliver
- Buthelezi Edith Zinhle
- Buxton Jesse Thomas
- Cabala Jan
- Cabanillas Noris Juan Carlos
- Caffarri Davide
- Caines Helen Louise
- Caliva Alberto
- Calvo Villar Ernesto
- Camerini Paolo
- Capon Aaron Allan
- Carena Francesco
- Carena Wisla
- Carnesecchi Francesca
- Castillo Castellanos Javier Ernesto
- Castro Andrew John
- Casula Ester Anna Rita
- Ceballos Sanchez Cesar
- Chandra Sinjini
- Chang Beomsu
- Chang Wan
- Chapeland Sylvain
- Chartier Marielle
- Chattopadhyay Subhasis
- Chattopadhyay Sukalyan
- Chauvin Alex
- Cheshkov Cvetan Valeriev
- Cheynis Brigitte
- Chibante Barroso Vasco Miguel
- Cho Soyeon
- Chochula Peter
- Chojnacki Marek
- Choudhury Subikash
- Chowdhury Tasnuva
- Christakoglou Panagiotis
- Christensen Christian Holm
- Christiansen Peter
- Chujo Tatsuya
- Chung Suh-urk
- Chunhui Zhang
- Cicalo Corrado
- Cifarelli Luisa
- Cindolo Federico
- Cleymans Jean Willy Andre
- Colamaria Fabio Filippo
- Colella Domenico
- Collu Alberto
- Colocci Manuel
- Concas Matteo
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- Conesa Del Valle Zaida
- Contreras Nuno Jesus Guillermo
- Cormier Thomas Michael
- Corrales Morales Yasser
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- Cortes Maldonado Ismael
- Cortese Pietro
- Cosentino Mauro Rogerio
- Costa Filippo
- Costanza Susanna
- Crkovska Jana
- Crochet Philippe
- Cuautle Flores Eleazar
- Cunqueiro Mendez Leticia
- Dahms Torsten
- Dainese Andrea
- Danisch Meike Charlotte
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- Das Debasish
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- De Caro Annalisa
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- Divia Roberto
- Djuvsland Oeystein
- Dobrigkeit Chinellato David
- Dobrin Alexandru Florin
- Domenicis Gimenez Diogenes
- Dominguez Rosas Edgar
- Donigus Benjamin
- Dordic Olja
- Duarte Galvan Carlos
- Dubey Anand Kumar
- Dubla Andrea
- Ducroux Laurent
- Dudi Sandeep
- Duggal Ashpreet Kaur
- Dukhishyam Mallick
- Dupieux Pascal
- Ehlers Iii Raymond James
- Elia Domenico
- Endress Eric
- Engel Heiko
- Epple Eliane
- Erazmus Barbara Ewa
- Erhardt Filip
- Espagnon Bruno
- Espinoza Beltran Lucina Gabriela
- Eulisse Giulio
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- Evans David
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- Feldkamp Linus
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- Feofilov Grigorii
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- Ferreira Natal Da Luz Pedro Hugo
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- Gianotti Paola
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- Giubilato Piero
- Gladysz-dziadus Ewa
- Glassel Peter
- Gomez Coral Diego Mauricio
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- Gorlich Lidia Maria
- Gotovac Sven
- Grabski Varlen
- Graczykowski Lukasz Kamil
- Graham Katie Leanne
- Greiner Leo Clifford
- Grelli Alessandro
- Grigoras Costin
- Grigoryan Ara
- Grigoryan Smbat
- Grigoryev Vladislav
- Gronefeld Julius Maximilian
- Grosa Fabrizio
- Grosse-oetringhaus Jan Fiete
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- Guerzoni Barbara
- Gulbrandsen Kristjan Herlache
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- Hadjidakis Cynthia Marie
- Hamagaki Hideki
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- Hellbar Ernst
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- Herrmann Florian
- Hess Benjamin Andreas
- Hetland Kristin Fanebust
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- Hohlweger Bernhard
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- Hornung Sebastian
- Hosokawa Ritsuya
- Hristov Peter Zahariev
- Hughes Charles
- Humanic Thomas
- Hussain Nur
- Hussain Tahir
- Hutter Dirk
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- Iga Buitron Sergio Arturo
- Ilkaev Radiy
- Inaba Motoi
- Ippolitov Mikhail
- Islam Md Samsul
- Ivanov Marian
- Ivanov Vladimir
- Izucheev Vladimir
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- Jadlovska Slavka
- Jadlovsky Jan
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- Jimenez Bustamante Raul Tonatiuh
- Jones Peter Graham
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- Kalweit Alexander Philipp
- Kang Ju Hwan
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- Kar Somnath
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- Karavichev Oleg
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- Karczmarczyk Przemyslaw
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- Kebschull Udo Wolfgang
- Keidel Ralf
- Keijdener Darius Laurens
- Keil Markus
- Ketzer Bernhard Franz
- Khabanova Zhanna
- Khan Mohammed Mohisin
- Khan Palash
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- Khanzadeev Alexei
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- Khuntia Arvind
- Kielbowicz Miroslaw Marek
- Kileng Bjarte
- Kim Byungchul
- Kim Daehyeok
- Kim Dong Jo
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- Kim Jiyoung
- Kim Minjung
- Kim Se Yong
- Kim Taesoo
- Kirsch Stefan
- Kisel Ivan
- Kiselev Sergey
- Kisiel Adam Ryszard
- Kiss Gabor
- Klay Jennifer Lynn
- Klein Carsten
- Klein Jochen
- Klein-boesing Christian
- Klewin Sebastian
- Kluge Alexander
- Knichel Michael Linus
- Knospe Anders Garritt
- Kobdaj Chinorat
- Kohler Markus Konrad
- Kollegger Thorsten
- Kondratev Valerii
- Kondratyeva Natalia
- Kondratyuk Evgeny
- Konevskikh Artem
- Konyushikhin Maxim
- Kopcik Michal
- Kour Mandeep
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- Kovalenko Oleksandr
- Kovalenko Vladimir
- Kowalski Marek
- Koyithatta Meethaleveedu Greeshma
- Kralik Ivan
- Kravcakova Adela
- Kreis Lukas
- Krivda Marian
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- Krzewicki Mikolaj
- Kubera Andrew Michael
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- Okubo Tsubasa
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- Oliver Michael Henry
- Onderwaater Jacobus
- Oppedisano Chiara
- Orava Risto
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- Ortiz Velasquez Antonio
- Oskarsson Anders Nils Erik
- Otwinowski Jacek Tomasz
- Oyama Ken
- Ozelin De Lima Pimentel Lais
- Pachmayer Yvonne Chiara
- Pacik Vojtech
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- Pahula Hewage Sandun
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- Patra Rajendra Nath
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- Peng Xinye
- Pereira Da Costa Hugo Denis Antonio
- Pereira Luis Gustavo
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- Poghosyan Martin
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- Poonsawat Wanchaloem
- Pop Amalia
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- Porteboeuf Sarah Julie
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- Pshenichnov Igor
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- Punin Valery
- Putschke Jorn Henning
- Raha Sibaji
- Rajput Sonia
- Rak Jan
- Rakotozafindrabe Andry Malala
- Ramello Luciano
- Rami Fouad
- Ramillien Barret Valerie
- Rana Dhan Bahadur
- Raniwala Rashmi
- Raniwala Sudhir
- Rasanen Sami Sakari
- Rascanu Bogdan Theodor
- Rathee Deepika
- Ratza Viktor
- Ravasenga Ivan
- Read Kenneth Francis
- Redlich Krzysztof
- Rehman Attiq Ur
- Reichelt Patrick Simon
- Reidt Felix
- Ren Xiaowen
- Renfordt Rainer Arno Ernst
- Reshetin Andrey
- Reygers Klaus Johannes
- Riabov Viktor
- Richert Tuva Ora Herenui
- Richter Matthias Rudolph
- Riedler Petra
- Riegler Werner
- Riggi Francesco
- Ristea Catalin-lucian
- Rodriguez Cahuantzi Mario
- Roeed Ketil
- Roehrich Dieter
- Rogochaya Elena
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- Rojas Torres Solangel
- Rokita Przemyslaw Stefan
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- Rosnet Philippe
- Rossi Andrea
- Rotondi Alberto
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- Roy Christelle Sophie
- Roy Pradip Kumar
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- Rui Rinaldo
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- Zhang Yonghong
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- Zhou You
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- Zmeskal Johann
- Zou Shuguang
- Publication venue
- Publication date
- 01/01/2017
- Field of study
Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
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- Abozied Hesham
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- Lohmann Tibor Karl
- Lohse Helmut Alfredo Segovia
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- Lyra Humberto Fenner
- Mabood Waleed
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- Maguire Patrick J.
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- Mahmood Fahad
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- Mallmann Christoph
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- Mambrilla Sara
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- Martins Ana
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- MartĂnez Eunate Ganuza
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- Meead Adullah
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- Nassar Mahmoud A.
- Nasser Sara
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- Ntalouka Maria P.
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- Oludara Mobolaji
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- Omer Mohammed Eltahier Abdalla
- Ong Chon Sum
- Onyeagwara Ngozi
- Onyemaechi Ndubuisi
- Ooi Rucira
- Orecchia Luca
- Ornaghi Sara
- Orsoo Soyombo
- Ortega Eduardo Nieto
- Osborn Tamara
- Oshodi Yusuf
- Osman Hany
- Osman Osama Saeed
- Osterhoff Georg
- Othman Ahmad Faidzal
- Othman Amani Alsayd Abdulsalam
- Othman Rema
- Otify Esraa
- Otokwala Job
- Oung Thida
- Oyinloye Oluwaseun
- Ozair Ahmad
- Ozkan Omer Faruk
- Ozmen Berk Baris
- Paal Peter
- Pachajoa Diana Alejandra Pantoja
- Pacheco Glenda Marina Falcon
- Pacilio Carlo Alberto
- Pacilli Maurizio
- Padmore Greg
- Page Richard
- Paiella Salvatore
- Palacios Nelson Morales
- Palepa Anna
- Palini Gian Marco
- Palmisano Silvia
- Palomba Giuseppe
- Panahi Pedram
- Panda Bijnya
- Pandey Diwakar
- Panduro-Correa Vicky
- Pang Tony
- Paniagua Ladislao Cayetano
- Panieri Eugenio
- Pantuso Gianni
- Papa Adrian
- Papa Mario Virgilio
- Papadoliopoulou Maria
- Papagni Vincenzo
- Papalia Rocco
- Papatheodorou Panayiotis
- Papavasiliou Kyriakos
- Paranjape Charudutt
- Paranyak Mykola
- Paraskevas Kosmas I.
- Paraskevopoulos Konstantinos
- Parini Sara
- Park James
- Parker Dominic
- Parker Robert
- Parmar Chetan
- Parray Fazl
- Parry James
- Parvez Elena
- Parwaiz Hammad
- Pascale Angelo
- Pascale Giovanni
- Pascale Marco Maria
- Pascarella Giuseppe
- Paspala Anna
- Pata Francesco
- Patel Panna
- Patel Tapan
- Patkar Shraddha
- Patrone Renato
- Pattacini Gianmaria Casoni
- Payne Rachel
- Pazmiño Patricio Andrés Freile
- Peckham-Cooper Adam
- Pecoraro Felice
- Pedini Domiziana
- Pejkova Sofija
- Pekcici Mevlut Recep
- Pellacani Arrigo
- Pellini Raul
- Pellino Gianluca
- Peltrini Roberto
- Peral Ana
- Perez-Chrzanowska Hanna
- Perfecto Arkaitz
- Peristeri Dimitra
- Perivoliotis Konstantinos
- Peros Georgios
- Perra Teresa
- Perrone Gennaro
- Perrotta Gerardo
- Persad Amit
- Pertea Mihaela
- Pessaux Patrick
- Petagna Lorenzo
- Petersen Maria Laura
- Petrone Patrizio
- Petrucciani NiccolĂČ
- Petruzzi Gerardo
- Pettigrove K.L.
- Phillips Jonathan
- Picardi Biagio
- Picchetto Andrea
- Picciariello Arcangelo
- Picciochi Maria
- Pickett Gwynedd
- Picotti Veronica
- Pieteris Linas
- Pigeolet Manon
- Pilkington Isobel
- Pillerstorff Robert
- Pineda Ana MejĂa
- Pinkney Thomas
- Pinney L.
- Pinotti Enrico
- Pinto Romina
- Piozzi Guglielmo NiccolĂČ
- Pira Biagia La
- Pires Robinson Esteves
- Pirola Giacomo Maria
- Pirozzi Brunella Maria
- Pirrello Roberto
- Pirzada Muhammad Taqi
- Pissaridou Maria Katerina
- Pitcher Meron
- Pitoni Sara
- Pizzini Paolo
- Pk Parvathy
- Plata-Bello Julio
- Pockney Peter
- Podda Mauro
- Poillucci Gaetano
- Pollok Joerg Matthias
- Pontecorvi Emanuele
- Porcu Alberto
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- Potten Stephanie
- Pournaras Dimitri
- Power Nicholas
- Prada Carlos
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- Pramesh C.S.
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- Prodromidou Anastasia
- Proud David
- Prucher Gian Marco
- Prusty Lydia
- Pu Jingya Jane
- Pucher Philip
- Punjabi Prakash P
- Puri Ajay
- Purich Kieran
- PĂ©rez Beatriz GĂłmez
- PĂ©rez-BertĂłlez Sonia
- Qader Kawthar
- Qin Kirby R.
- Quadri Oladeji
- Quaresima Silvia
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- Rabie Mohamed
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- Rodrigues Sara Castanheira
- Rodriguez H. Alejandro
- Rodriguez Magdiel
- Rodriguez-Lopez Mario
- RodrĂguez Lorena Varela
- Rokohl Alexander Christopher
- Roland Christina L
- Rolinger Jens
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- Schröder Lars
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- Sebai Amine
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- Seenivasagam Rajkumar Kottayasamy
- Segalini Edoardo
- Segaren Neil
- Segaren Nicholas
- Seglenieks Richard
- Segura-Sampedro Juan José
- Seguya Amina
- Seidu Anwar Sadat
- Seiwerth Ingmar
- SekuliÄ Aleksandar
- Semple Abigail
- Sen Comert
- Senanayake Kithsiri Janakantha
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- Seneviratne Sanjeewa
- Senni Carlotta
- Sensi Bruno
- Seraj Shaikh Sanjid
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- Serra Margherita
- Serra Marta Lopes
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- Shaban Naseebah
- Shaddad Ebrahim
- Shaerf Daniel
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- Shah Hemina
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- Shah Karishma
- Shah Pritik A
- Shah Vinay
- Shaikh Shafaque
- Shalaby Mostafa
- Shalhoub Joseph
- Shamim Shahzad
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- Sharma Shilpa
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- Sheen Jonathon
- Shehata Sherif
- Shehta Ahmed
- Sheik Shahila
- Sheikh Eman
- Shekleton Florence
- Shelat Vishal
- Shelmerdine Lauren
- Sherif Ahmed Elshawadfy
- Shiban Ehab
- Shiota Masaki
- Shirazi Ahmed
- Shiwani Haaris
- Shmukler Daniel
- Shokor Muntaser Abu
- Sholadoye Tunde T.
- Shoukrie Shoukrie I. M.
- Shrestha Rashmit
- Siboe Mark
- Sica Giuseppe
- Siddig Esra
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- Simoes Joana
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- SimÔes Joana Filipa Ferreira
- Singer Georg
- Singh Abhinav
- Singh Baljit
- Singh Kathryn
- Singh Rajdeep
- Singh Tanveer
- Sinnerton Robert
- Siragusa Leandro
- Sivaprakasam Rajesh
- Skipworth Richard Je
- Slavchev Mihail
- Sleem Adham
- Smati Ismail
- Smelt Jeremy
- Smith A.
- Smolle-Juettner Freyja-Maria
- Sodhai Vivek
- Sofi Khalid
- Sohrabi Catrin
- Soibiharry Adaiah
- Sokolov Manol
- Solaini Leonardo
- Sole Oriol Martin
- Sole-Sedeno Josep M.
- Soljic Martina
- Solli Piergiorgio
- Soon Wai Cheong
- Sorbi Flavia
- Sotiropoulou Maria
- Sotudeh Mohadeseh
- Souadka Amine
- Soucheiron Maria Coronas
- Soytas Mustafa
- Sozzi Giulio
- Sparavigna Marco
- Spartalis Michael
- Spellar Kayleigh
- Spiers Harry V. M.
- Spina Alfio
- Spriano Giuseppe
- Squiers John
- Stabler Robert
- Stamatakis Emmanouil
- Stamatis Konstantinos
- Starr Nichole
- Stather Philip
- Stevens Sean
- Stevenson Andrew
- Stewart Grant D.
- Stijns Jasper
- Stogowski Piotr Tomasz
- Stoleriu Mircea Gabriel
- Stoyanov Vladislav
- Street John
- Strotmann Johanna Josefine
- Stroumpoulis Konstantinos
- Su Yu-Xiong
- Suarez Sara Busto
- Subramani Yamini
- Subramaniam Sentilnathan
- Sue-Chue-Lam Colin
- Suer Muhammed Salih
- Sulaiman Bilal
- Sultania Mahesh
- Sundarraju Shalini
- Sungurtekin Hulya
- Suresh Sreelakshmi
- Surya Ilham Utama
- Swed Sarya
- Syllaios Athanasios
- Symeonidis Dimitrios
- SzabĂłmihĂĄlyovĂĄ KatarĂna
- Szakmany Tamas
- Szatmary Peter
- Sztipits TamĂĄs
- Szyluk Karol
- SĂĄ-Marta Eduarda
- Sånchez Alberto Cabañero
- SĂĄnchez Rosa
- Sånchez-Guillén Luis
- SĂŒleyman Marlen
- Tadic Boris
- Taha Anas
- Taha-Mehlitz Stephanie
- Tailor Bhavesh
- Taj Eldeen Samaher Taj Eldeen Hassan
- Takeda Flavio Roberto
- Takkenberg Marijn
- Talat Nabila
- Tallon-Aguilar Luis
- Talwar Rishi
- Tamayo Beatriz Villota
- Tamburello Sara
- Tamini NicolĂČ
- Tammo Ămer
- Tamoos Khalil
- Tampaki Ekaterini Christina
- Tampakis Athanasios
- Tan Chih Ying
- Tan Shawn Jia Hwang
- Tanal Mert
- Tanas Yousef
- Tang Alethea
- Tang Yita
- Tani Sobhana Iftekhar
- Tantraworasin Apichat
- Tantri Aida Rosita
- Tapia-Herrero Ana-MarĂa
- Tarek Ahmed
- Tariq Aiman
- Tarle Marko
- Tarsitano Achille
- Tartaglia Dario
- Tartaglia Nicola
- Tashkandi Wail
- Taskiran Cagatay
- Tatar Cihad
- Tatsis Dimitris
- Tawalbeh Ra'Fat
- Tawiah Augustine
- Tebha Sameer
- Techapongsatorn Suphakarn
- Teixeira Pedro
- Tejero-Pintor Francisco J.
- Tellez Karla Susana Martin
- Tellez Luis Garcia-Sancho
- Thaha Mohamed Adhnan
- Thakar Sumit
- Thaw May Htoo
- Theivendran Kanthan
- Thekkinkattil Dinesh
- Theochari Nikoletta
- Theodoropoulos George
- Theophilidou Elena
- Thereska Dariel
- Thiruchandran Gajendiran
- Thomakos Nikolaos
- Thomas Bradley
- Thomas Jerin Jose
- Thuduvage Vasanthika
- Thumbadoo Ruben
- Tian Sarah
- Tidjane Anisse
- Tirloni Luca
- Toia Francesca
- Tokidis Evripidis
- Tokocin Merve
- Tolani Musliu Adetola
- Toma Elena Adelina
- Tomasicchio Giovanni
- Tomlinson James
- Tonini Valeria
- Torre Beatrice
- Torregrosa Cristina
- Torun Bahar Canbay
- Tottman R.
- Tousidonis Manuel
- Trabulsi Nora
- Tranca Sebastian
- Trebol Jacobo
- Trejo-Avila Mario
- Triantafyllou Alexandra
- Triantafyllou Tania
- Trifunovski Aleksandar
- Tripathi Manjul
- Tripathi Prashant
- Tripathy Sujit
- Trivik-Barrientos Felipe
- Trostchansky Ivan
- Trulson Alexander
- Trungu Sokol
- Truss Adam
- Tsakiridis Ioannis
- Tsakiridis Nikolaos
- Tsiantoula Paraskevi
- Tsironis Dimitrios
- Tsolakidis Alexandros
- Tsoulfas Georgios
- Tucker Olga
- Tuech Jean Jacques
- Turan Alparslan
- Turi Stefano
- Turna Akif
- Turrado-Rodriguez Victor
- Turri Giulia
- Tutino Roberta
- Tuyishime Eugene
- Tzelves Lazaros
- Tzima Ioanna
- Tzimas George
- Ubiali Paolo
- Ubom Akaninyene Eseme
- Ugwu Aloy Okechukwu
- Ugwu Ebere
- Ugwu Ifeanyichukwu
- Ul Huda Maria Noor
- Ulas Ali Bilal
- Uldry Emilie
- Ulgur Hanife Seyda
- Ulkucu Attila
- Ulman Elif Akbas
- Ulman Hilmican
- UlutaĆ Mehmet EĆref
- Underwood Kirk
- Unsworth Richard
- Uprak Tevfik Kivilcim
- Urriza Pablo Vallés
- Usman Muhammad
- Usman Mustapha Ibrahim
- Vaassen Lauretta
- Vaccara Vincenzo La
- Vagena Xanthoula
- Vagge Aldo
- Vailas Michail
- Valadez Andrea Estefania Cueto
- Valadez Tania Abigail Cueto
- Valanci Sofia
- Valdespino Cristina Puentes
- Valeanu Liana
- Valioulis Ioannis
- Valladares Sergio ChĂĄvez
- Vallve-Bernal Marc
- Van Acker Jill
- Van Den Eynde Jef
- Van Goor Harry
- Van Vliet Helen
- Van Wyk Naomi Natasha
- Vanni Camilla
- Vas Aurelia
- Vasarhelyi Edward
- Vaschetti Roberto
- Vassiliu Panteleimon
- Vatansever Dogan
- Vatish Jamie
- Vaughan-Shaw Peter G.
- Vaysburg Dennis
- Veglia Antonella
- Velten Markus
- VelĂĄzquez Maria Jose Martinez
- Venkatappa Sunil Kumar
- Venketeswaran Meenakshi
- Venskutonis Donatas
- Verbic Milena Senica
- Verdi Daunia
- Vergara-Fernandez Omar
- Verhoeff Kevin
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Verre Luigi
- Vida Lucian
- Vidya Raghavan
- Viglietta Edoardo
- Vijay Vardhini
- Vijgen Guy
- VilarĂł Blanca Capdevila
- Villanueva Julio
- Vilz Tim O.
- Vincent Elizabeth
- Vinci Danilo
- Viola Simona
- Violante Tommaso
- Vishnoi Jeewan Ram
- Vissapragada Ravi
- Vivancos Laura Guillamon
- Vives Josep Maria Muñoz
- Vizzielli Giuseppe
- Vohra Lubna
- Vokshi Ismail
- Vosinakis Christos
- Våsquez Javier Alberto Gutiérrez
- VĂĄzquez Gil
- VĂĄzquez Irene Ortega
- VÇcÇraĆu Andrei Bogdan
- Wade Ryckie
- Wafi Omar
- Wagner Gabriela
- Wallis Christopher
- Wanjara Samuel
- Waqar Shahzad Hussain
- Warden Claire
- Warner Christian
- Wasim D.
- Wason Shaun
- Wasserman Isaac
- Watcyn-Jones Tom
- Waterson Ben
- Watson David
- Watson Matthew
- Weber Clemens
- Wheatstone P.
- Wheeler James
- Wheldon Luke
- White Michelle
- White Stuart
- White William
- Wickramasinghe Dakshitha
- Widmer Lukas Werner
- Wiedemann Dominik
- Wiesinger Clemens Georg
- Wijekoon Naveen
- Wijenayake Wasantha
- Wijeyaratne Manuk
- Wijeysundera Duminda
- Wiles Matthew
- Wilkin Richard
- Wilkins Alex
- Wilkins James
- William Tinka George
- Williams Omolara Modupe
- Williams Shekinah
- Windsor John
- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
- Wu Fiona
- Wurm Markus
- Xenaki Sofia
- Yadev Ip
- Yahaya Ahmad Shuib
- Yakubu Mustapha
- Yang Wah
- Yanik Ăzge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- ZarĂĄnd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha HorĂĄcio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ăvila Clara Castro
- ĂlgĂ„ Andreas
- Ăakici Mehmet Ăaǧlar
- Ăelik Enes
- Ăelik Meryem Nur
- Ăzçay Necdet
- Ćevik HĂŒsnĂŒ
- Ć antak Goran
- Ć imko KristiĂĄn
- ĆœateckĂœ Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and lowâmiddle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of âsingle-useâ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for lowâmiddle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both highâ and lowâmiddleâincome countries
Primary osseous Burkitt lymphoma with nodal and intracardiac metastases in a child
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/03/2017
- Field of study
Burkitt lymphoma (BL) is the most frequent non-Hodgkin lymphoma in pediatric patients, accounting for approximately 34% of the cases of lymphoma in children. This subtype of non-Hodgkin lymphoma was first described in 1958 as a monoclonal proliferation of B cell lymphocytes. Cardiac involvement of BL in association with osseous compromise and lymphadenopathy is rare and poorly documented. We report a case of femur primary BL in an 8-year-old boy with metastatic cardiac involvement, retroperitoneal and iliofemoral lymphadenopathy, and hepatosplenomegaly. We highlight the diagnostic challenge in a patient with clinical nonspecific findings and systemic disease
Experimental Investigations on the Tribological Effects of Alumina-Nanofluids in a Through-Flow-Test-Rig
- Publication venue
- Digital Commons@Georgia Southern
- Publication date
- 01/10/2015
- Field of study
This paper was published in the STLE-Tribology Frontiers Conference
Exploratory Research Work on Tribological Effects of Nanofluids
- Publication venue
- Digital Commons@Georgia Southern
- Publication date
- 01/05/2011
- Field of study
This paper was published in the Proc. of STLE 2011 Annual Meeting
NeuropatĂa autonĂłmica diabĂ©tica cardiovascular
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/03/2013
- Field of study
La neuropatĂa autonĂłmica diabĂ©tica cardiovascular es un trastorno en el cual una alteraciĂłn en la regulaciĂłn del sistema nervioso cardiovascular, por parte del sistema nervioso autĂłnomo, desemboca en una constelaciĂłn de sĂntomas, que pueden ir desde intolerancia al ejercicio hasta muerte sĂșbita. Si bien no se conoce su prevalencia exacta, se estima que es alta en pacientes diabĂ©ticos, particularmente en aquellos con diabetes de larga data y con presencia de otras comorbilidades. Su reconocimiento temprano puede facilitar el manejo de estos pacientes y a su vez disminuir los costos asociados a pruebas e intervenciones innecesarias con el objetivo de evitar complicaciones asociadas con la enfermedad
Erectile Dysfunction Among HIV Patients Undergoing Highly Active Antiretroviral Therapy: Dyslipidemia as a Main Risk Factor
- Author
- Publication venue
- 'Wiley'
- Publication date
- 24/03/2014
- Field of study
Objective: To assess the prevalence and risk factors of erectile dysfunction (ED) in HIV patients from the HIV clinic of a tertiary referral center in Mexico City.
Design: Prevalence was obtained from crossâsectional studies, and the International Index of Erectile Function (IIEF), a standardized method, was used to assess ED.
Methods: A crossâsectional study was performed in the HIV clinic. Participants completed the IIEF to allow ED assessment. Information on demographics, clinical and HIVârelated variables was retrieved from their medical records.
Results: One hundred and nine patients were included, with a mean age of 39.9â±â8.8 years. ED was present in 65.1% of the individuals. Patients had been diagnosed with HIV for a mean of 92.7â±â70.3 months and had undergone a mean 56.4â±â45.5 months of HAART. The only variable associated with ED in the univariate analysis was dyslipidemia, and this association was also found in the multivariate analysis (Pâ=â0.01).
Conclusions: ED is highly prevalent in HIV patients. Dyslipidemia should be considered as a risk factor for ED in HIV patients. RomeroâVelez G, LiskerâCervantes A, VilledaâSandoval CI, Sotomayor de Zavaleta M, OlveraâPosada D, SierraâMadero JG, ArreguinâCamacho LO, and CastillejosâMolina RA. Erectile dysfunction among HIV patients undergoing highly active antiretroviral therapy: Dyslipidemia as a main risk factor. Sex Med 2014;2:24â30
Multiplicity dependence of light (anti-)nuclei production in pâPb collisions at sNN=5.02 TeV
- Author
- Acharya Shreyasi
- Adamova Dagmar
- Adhya Souvik Priyam
- Adler Alexander
- Adolfsson Jonatan
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahmad Shakeel
- Ahn Sang Un
- Akindinov Alexander
- Al-turany Mohammad
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alfanda Haidar Mas'ud
- Alfaro Molina Jose Ruben
- Ali Bushra
- Ali Yasir
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altenkamper Lucas
- Altsybeev Igor
- Anaam Mustafa Naji
- Andrei Cristian
- Andreou Dimitra
- Andrews Harry Arthur
- Andronic Anton
- Angeletti Massimo
- Anguelov Venelin
- Anson Christopher Daniel
- Anticic Tome
- Antinori Federico
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- Aphecetche Laurent Bernard
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- Ullaland Kjetil
- Umaka Ejiro Naomi
- Uras Antonio
- Usai Gianluca
- Utrobicic Antonija
- Vala Martin
- Valle Nicolo'
- Vallero Sara
- Van Der Kolk Naomi
- Van Doremalen Lennart
- Van Leeuwen Marco
- Vande Vyvre Pierre
- Varga Dezso
- Varga Zoltan
- Varga-kofarago Monika
- Vargyas Marton
- Varma Raghava
- Vasileiou Maria
- Vasiliev Andrey
- Vazquez Doce Oton
- Vazquez Rueda Omar
- Vechernin Vladimir
- Veen Annelies Marianne
- Vercellin Ermanno
- Vergara Limon Sergio
- Vermunt Lucas Anne
- Vernet Renaud
- Vertesi Robert
- Vickovic Linda
- Viinikainen Jussi Samuli
- Vilakazi Zabulon
- Villalobos Baillie Orlando
- Villatoro Tello Abraham
- Vino Gioacchino
- Vinogradov Alexander
- Virgili Tiziano
- Vislavicius Vytautas
- Vodopyanov Alexander
- Volkel Benedikt
- Volkl Martin Andreas
- Voloshin Kirill
- Voloshin Sergey
- Volpe Giacomo
- Von Haller Barthelemy
- Vorobyev Ivan
- Voscek Dominik
- Vrlakova Janka
- Wagner Boris
- Watanabe Yosuke
- Weber Michael
- Weber Steffen Georg
- Wegrzynek Adam Tadeusz
- Weiser Dennis Franz
- Wenzel Sandro Christian
- Wessels Johannes Peter
- Widmann Eberhard
- Wiechula Jens
- Wikne Jon
- Wilk Grzegorz Andrzej
- Wilkinson Jeremy John
- Willems Guido Alexander
- Willsher Emily Jade
- Windelband Bernd Stefan
- Witt William Edward
- Wu Yitao
- Xu Ran
- Yalcin Kuzu Serpil
- Yamakawa Kosei
- Yang Shiming
- Yano Satoshi
- Yasin Zafar
- Yin Zhongbao
- Yokoyama Hiroki
- Yoo In Kwon
- Yoon Jin Hee
- Yuan Shiming
- Yuncu Alperen
- Yurchenko Volodymyr
- Zaccolo Valentina
- Zaman Ali
- Zampolli Chiara
- Zardoshti Nima
- Zarochentsev Andrey
- Zavada Petr
- Zavyalov Nikolay
- Zbroszczyk Hanna Paulina
- Zhalov Mikhail
- Zhang Xiaoming
- Zhang Zuman
- Zhao Chengxin
- Zherebchevskii Vladimir
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
- Zhou Zhuo
- Zhu Jianhui
- Zhu Ya
- Zichichi Antonino
- Zimmermann Markus Bernhard
- Zinovjev Gennady
- Zurlo Nicola
- Publication venue
- Publication date
- 01/01/2019
- Field of study
The measurement of the deuteron and anti-deuteron production in the rapidity range â1 < y < 0 as a function of transverse momentum and event multiplicity in pâPb collisions at âsNN = 5.02 TeV is presented. (Anti-)deuterons are identified via their specific energy loss dE/dx and via their time-of- flight. Their production in pâPb collisions is compared to pp and PbâPb collisions and is discussed within the context of thermal and coalescence models. The ratio of integrated yields of deuterons to protons (d/p) shows a significant increase as a function of the charged-particle multiplicity of the event starting from values similar to those observed in pp collisions at low multiplicities and approaching those observed in PbâPb collisions at high multiplicities. The mean transverse particle momenta are extracted from the deuteron spectra and the values are similar to those obtained for p and particles. Thus, deuteron spectra do not follow mass ordering. This behaviour is in contrast to the trend observed for non-composite particles in pâPb collisions. In addition, the production of the rare 3He and 3He nuclei has been studied. The spectrum corresponding to all non-single diffractive p-Pb collisions is obtained in the rapidity window â1 < y < 0 and the pT-integrated yield dN/dy is extracted. It is found that the yields of protons, deuterons, and 3He, normalised by the spin degeneracy factor, follow an exponential decrease with mass number
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