SOBREPESO EN EL LACTANTE DEL ÁREA METROPOLITANA DE MONTERREY, N.L., MEXICO

La etapa Lactante es una alternativa de abordaje en la lucha contra la obesidad. Se ha demostrado que existe una relación entre el exceso de peso en ésta etapa, con las principales problemas de salud pública; con base en lo anterior, es necesario buscar factores modificables en el comportamiento de los encargados del cuidado del infante y del equipo de salud para crear conductas que propicien el adecuado desarrollo del individuo. El objetivo de éste estudio es determinar la prevalencia del exceso de peso en lactantes del área metropolitana de Monterrey, a partir de usuarios del programa de atención del niño sano del IMSS, provenientes de seis unidades de medicina familiar. Se estudiaron 400 lactantes a través de la medición de peso y talla, para clasificarlos mediante las tablas diagnósticas nutricionales de la NCHS-CDC/OMS. Se obtuvo una prevalencia del exceso de peso de los lactantes estudiados equivalente al 43.23%. Mostrando que el exceso de peso representa un problema de salud pública creciente en México, el cual requiere el replanteamiento de los programas preventivos en éste sector demográfico, buscando aquellos niños que están adquiriendo patrones patológicos de comportamiento en su ingesta alimentaria. AbstractThe infant stage is an alternative in boarding the struggle against obesity. There has been demonstrated that a relation exists between overweight in this period with the current issues of public health. Due to this, it is necessary to search for adjustable factors in the carers and health team, in order to create appropriate behaviour that propitiates suiable development of the individual. The objective in this study was to determine the prevalence of overweight in Monterrey’s metropolitan area infants who assist the healthy child program from six primary health care units of the Mexican Institute of Social Security. There were studied 400 children under a year of age, to whom they there was realized measurement of weight and height, qualifying by means of the diagnostic nutritional tables of the NCHS-CDC/OMS. The results of this study show that the prevalence rates of excess body weight in infants under a year old in Monterrey’s Metropolitan area are 43.23%. There is a clear that excess body weight represents a problem of public health in México, which needs the rethinking of the preventive programs in this one population sector, in search of those children that are acquiring pathological bosses of behavior in food ingestionPalabras Clave: Lactante, prevalencia, exceso de peso, sobrepeso, obesidad, niños menores de un año

HEMOGLOBINA GLUCOSILADA: PRUEBA DE LABORATORIO NECESARIA PARA EL CONTROL METABOLICO DE PACIENTES MEXICANOS CON DIABETES MELLITUS TIPO 2.

Además de la determinación de glucosa en sangre en ayunas (FBG), la prueba de hemoglobinaglucosilada (HbA1c) es un indicador que evalúa el grado de control metabólico de todo pacientecon diabetes mellitus tipo 2. Aunque ambas pruebas se determinan rutinariamente en muchospaíses en el mundo, para el buen control metabólico del paciente diabético, en las instituciones desalud en México solo se basan en la prueba de FBG. Conocer si los pacientes con diabetes queacudían al Hospital No. 25, IMSS en Monterrey para su control clínico (después de una evaluaciónfísica basada solamente en la prueba de FBG), estuvieron bajo un buen o mal control metabólico.Se llevo a cabo un estudio de serie de casos en el cual se midieron las concentraciones de FBG yde HbA1c en 93 pacientes diabéticos bajo tratamiento (46 mujeres y 47 hombres, con un promediode edad de 54 años) que acudían a la consulta externa del Hospital No. 25. Para evaluar el nivelde control metabólico se usaron los criterios de la Asociación Americana de Diabetes (ADA) (lacual recomienda que los niveles de HbA1c deben ser mantenidos < 7.0%) y el criterio Europeo(que recomienda que los niveles de HbA1c deben ser mantenidos < 7.6%). Las determinaciones deFBG se realizaron en el Hospital No. 25 y las de HbA1c en el Centro de Investigación Biomédicadel Noreste (CIBIN). De acuerdo a la prueba de FBG, los médicos clínicos detectaron que el 52%de los pacientes tuvieron cifras 140 mg/dl (mal control metabólico). Por otro lado, utilizando laprueba de HbA1c, los 93 pacientes (100%) registraron niveles > a 8.0%. La prueba de HbA1cmostró que todos los pacientes tuvieron un mal control metabólico. Por lo tanto, es prioritario quelas autoridades implementen rutinariamente la prueba de HbAc1 en las instituciones de salud deMéxico y especialmente en Nuevo León dado que este Estado posee la mayor tasa de mortalidadpor diabetes (45%) a nivel nacional.AbstractGlycosylated hemoglobin (HbA1c) is a blood test that gives an estimate of the average blood sugar(glucose) for the previous three months. The fasting blood glucose (FBG) and HbA1cdeterminations give a well idea about the metabolic control of the diabetics. Both tests aredetermined routinely in many countries but into the Mexican Institutes of Health only the FBG test iscarried out for this purpose. The aim of this study was to know if non-insulin-dependent diabeticmellitus (NIDDM) outpatients attending in a clinical hospital of the IMSS after the physicianevaluation based only on the FBG test were under a good or bad metabolic control. At the sametime, we carried out the HbA1c test independently of the physician evaluation in order to know if theNIDDM patients were well evaluated. A serial case study was undertaken in which concentrations ofFBG and HbA1c were measured in 93 diabetics (under treatment) at the outpatient clinic of theIMSS in Monterrey, Mexico. A structured, self-administrated questionnaire was used to obtain dataon age, gender, duration of diabetes, a recent history of polydipsia, polyuria and polyphagia, height,weight, blood pressure, treatment kind, and BMI. The American Diabetic Association (ADA)(currently recommends that the HbA1c be maintained under 7.0%) and the European criteria(currently recommends that the HbA1c be maintained under 7.6%) were used to evaluate the levelof metabolic control. The 93 patients had HbA1C levels higher than 8.0% and FBG levels between63 and 300 mg/dl. According to ADA criteria and European criteria all the patients were out of goodmetabolic control. These points towards the HbA1c and FBG confirm the doubts about theusefulness of FBG values as a tool for assessing metabolic control. These results suggest a lowlevel in the practice of monitoring indicators in NIDDM. We suggest that the HbA1c test must betaken in account by the Mexican Institutes of Health to improve a better metabolic control in theirdiabetic patients.Palabras Clave: Diabetes, Tipo 2, Hemoglobina glucosilada, Diabetes, Type 2, Glycosylated hemoglobi

Evaluación de la fatiga en pacientes con artritis psoriásica y su asociación con otras variables de la enfermedad

Objetivo: evaluar la frecuencia de fatiga en pacientes con APs y su asociación con otras variables de la enfermedad

Linguistic and maternal genetic diversity are not correlated in Native Mexicans

Mesoamerica, defined as the broad linguistic and cultural area from middle southern Mexico to Costa Rica, might have played a pivotal role during the colonization of the American continent. The Mesoamerican isthmus has constituted an important geographic barrier that has severely restricted gene flow between North and South America in pre-historical times. Although the Native American component has been already described in admixed Mexican populations, few studies have been carried out in native Mexican populations. In this study, we present mitochondrial DNA (mtDNA) sequence data for the first hypervariable region (HVR-I) in 477 unrelated individuals belonging to 11 different native populations from Mexico. Almost all of the Native Mexican mtDNAs could be classified into the four pan-Amerindian haplogroups (A2, B2, C1, and D1); only two of them could be allocated to the rare Native American lineage D4h3. Their haplogroup phylogenies are clearly star-like, as expected from relatively young populations that have experienced diverse episodes of genetic drift (e.g., extensive isolation, genetic drift, and founder effects) and posterior population expansions. In agreement with this observation, Native Mexican populations show a high degree of heterogeneity in their patterns of haplogroup frequencies. Haplogroup X2a was absent in our samples, supporting previous observations where this clade was only detected in the American northernmost areas. The search for identical sequences in the American continent shows that, although Native Mexican populations seem to show a closer relationship to North American populations, they cannot be related to a single geographical region within the continent. Finally, we did not find significant population structure in the maternal lineages when considering the four main and distinct linguistic groups represented in our Mexican samples (Oto-Manguean, Uto-Aztecan, Tarascan, and Mayan), suggesting that genetic divergence predates linguistic diversification in Mexico

Measurement of the cross-section and charge asymmetry of WW bosons produced in proton-proton collisions at s=8\sqrt{s}=8 TeV with the ATLAS detector

This paper presents measurements of the $W^+ \rightarrow \mu^+\nu$ and $W^- \rightarrow \mu^-\nu$ cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS experiment at the LHC and correspond to a total integrated luminosity of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the 1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured with an uncertainty between 0.002 and 0.003. The results are compared with predictions based on next-to-next-to-leading-order calculations with various parton distribution functions and have the sensitivity to discriminate between them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables, submitted to EPJC. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13

Evaluation of the effects of erythritol on gene expression in Brucella abortus

Bacteria of the genus Brucella have the unusual capability to catabolize erythritol and this property has been associated with their virulence mainly because of the presence of erythritol in bovine foetal tissues and because the attenuated S19 vaccine strain is the only Brucella strain unable to oxydize erythritol. In this work we have analyzed the transcriptional changes produced in Brucella by erythritol by means of two high throughput approaches: RNA hybridization against a microarray containing most of Brucella ORF's constructed from the Brucella ORFeome and next generation sequencing of Brucella mRNA in an Illumina GAIIx platform. The results obtained showed the overexpression of a group of genes, many of them in a single cluster around the ery operon, able to co-ordinately mediate the transport and degradation of erythritol into three carbon atoms intermediates that will be then converted into fructose-6P (F6P) by gluconeogenesis. Other induced genes participating in the nonoxidative branch of the pentose phosphate shunt and the TCA may collaborate with the ery genes to conform an efficient degradation of sugars by this route. On the other hand, several routes of amino acid and nucleotide biosynthesis are up-regulated whilst amino acid transport and catabolism genes are down-regulated. These results corroborate previous descriptions indicating that in the presence of erythritol, this sugar was used preferentially over other compounds and provides a neat explanation of the the reported stimulation of growth induced by erythritol

Paleobiology of titanosaurs: reproduction, development, histology, pneumaticity, locomotion and neuroanatomy from the South American fossil record

Fil: García, Rodolfo A.. Instituto de Investigación en Paleobiología y Geología. Museo Provincial Carlos Ameghino. Cipolletti; ArgentinaFil: Salgado, Leonardo. Instituto de Investigación en Paleobiología y Geología. General Roca. Río Negro; ArgentinaFil: Fernández, Mariela. Inibioma-Centro Regional Universitario Bariloche. Bariloche. Río Negro; ArgentinaFil: Cerda, Ignacio A.. Instituto de Investigación en Paleobiología y Geología. Museo Provincial Carlos Ameghino. Cipolletti; ArgentinaFil: Carabajal, Ariana Paulina. Museo Carmen Funes. Plaza Huincul. Neuquén; ArgentinaFil: Otero, Alejandro. Museo de La Plata. Universidad Nacional de La Plata; ArgentinaFil: Coria, Rodolfo A.. Instituto de Paleobiología y Geología. Universidad Nacional de Río Negro. Neuquén; ArgentinaFil: Fiorelli, Lucas E.. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica. Anillaco. La Rioja; Argentin

A basal lithostrotian titanosaur (Dinosauria: Sauropoda) with a complete skull: Implications for the evolution and paleobiology of titanosauria

We describe Sarmientosaurus musacchioi gen. et sp. nov., a titanosaurian sauropod dinosaur from the Upper Cretaceous (Cenomanian - Turonian) Lower Member of the Bajo Barreal Formation of southern Chubut Province in central Patagonia, Argentina. The holotypic and only known specimen consists of an articulated, virtually complete skull and part of the cranial and middle cervical series. Sarmientosaurus exhibits the following distinctive features that we interpret as autapomorphies: (1) maximum diameter of orbit nearly 40% rostrocaudal length of cranium; (2) complex maxilla - lacrimal articulation, in which the lacrimal clasps the ascending ramus of the maxilla; (3) medial edge of caudal sector of maxillary ascending ramus bordering bony nasal aperture with low but distinct ridge; (4) ´tongue-like´ ventral process of quadratojugal that overlaps quadrate caudally; (5) separate foramina for all three branches of the trigeminal nerve; (6) absence of median venous canal connecting infundibular region to ventral part of brainstem; (7) subvertical premaxillary, procumbent maxillary, and recumbent dentary teeth; (8) cervical vertebrae with ´strut-like´ centroprezygapophyseal laminae; (9) extremely elongate and slender ossified tendon positioned ventrolateral to cervical vertebrae and ribs. The cranial endocast of Sarmientosaurus preserves some of the most complete information obtained to date regarding the brain and sensory systems of sauropods. Phylogenetic analysis recovers the new taxon as a basal member of Lithostrotia, as the most plesiomorphic titanosaurian to be preserved with a complete skull. Sarmientosaurus provides a wealth of new cranial evidence that reaffirms the close relationship of titanosaurs to Brachiosauridae. Moreover, the presence of the relatively derived lithostrotian Tapuiasaurus in Aptian deposits indicates that the new Patagonian genus represents a ´ghost lineage´ with a comparatively plesiomorphic craniodental form, the evolutionary history of which is missing for at least 13 million years of the Cretaceous. The skull anatomy of Sarmientosaurus suggests that multiple titanosaurian species with dissimilar cranial structures coexisted in the early Late Cretaceous of southern South America. Furthermore, the new taxon possesses a number of distinctive morphologies - such as the ossified cervical tendon, extremely pneumatized cervical vertebrae, and a habitually downward- facing snout - that have rarely, if ever, been documented in other titanosaurs, thus broadening our understanding of the anatomical diversity of this remarkable sauropod clade. The latter two features were convergently acquired by at least one penecontemporaneous diplodocoid, and may represent mutual specializations for consuming low-growing vegetation.Fil: Martínez, Rubén Darío. Universidad Nacional de la Patagonia; ArgentinaFil: Lamanna, Matthew C.. Carnegie Museum Of Natural History; Estados UnidosFil: Novas, Fernando Emilio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "bernardino Rivadavia"; ArgentinaFil: Ridgely, Ryan C.. Ohio University College Of Osteopathic Medicine; Estados UnidosFil: Casal, Gabriel. Universidad Nacional de la Patagonia; ArgentinaFil: Martínez, Javier E.. Hospital Regional de Comodoro Rivadavia; ArgentinaFil: Vita, Javier R.. Resonancia Magnética Borelli; ArgentinaFil: Witmer, Lawrence M.. Ohio University College Of Osteopathic Medicine; Estados Unido

Consensus on complementary feeding from the Latin American Society for Pediatric Gastroenterology, Hepatology and Nutrition: COCO 2023

Abstract Complementary feeding (CF) is defined as infant feeding that complements breastfeeding or, alternatively, breastfeeding with a breast milk substitute, and is a process that goes beyond simply providing guidance on what and how to introduce foods. The information provided by health professionals should be up-to-date and evidence-based. There are different guidelines or position papers at the international level, which, although most of the recommendations may be applicable, there are some others that require regionalization or adaptation to the conditions and reality of each area. The Nutrition working group of the Latin American Society of Pediatric Gastroenterology, Hepatology and Nutrition convened a group of experts, representatives from each of the countries that make up the society, with the objective of developing a consensus on CA, incorporating, when possible, local information that adapts to the reality of the region. The purpose of this document is to show the results of this work. Through Delphi methodology, a total of 34 statements or statements regarding relevant aspects of CA were evaluated, discussed and voted upon.Resumen La alimentación complementaria (AC) se define como la alimentación de los lactantes que complementa a la lactancia materna o en su defecto, a la lactancia con un sucedáneo de la leche materna, y es un proceso que va más allá de simplemente una guía sobre qué y cómo introducir los alimentos. La información brindada por parte de los profesionales de la salud debe ser actualizada y basada en evidencia. Existen diferentes guías o documentos de posición a nivel internacional, que, aunque la mayoría de las recomendaciones pueden ser aplicables, hay algunas otras que requieren una regionalización o adecuación a las condiciones y realidad de cada zona. El grupo de trabajo de Nutrición de la Sociedad Latinoamericana de Gastroenterología, Hepatología y Nutrición Pediátrica convocó a un grupo de expertos, representantes de cada uno de los países que conforman la sociedad, con el objetivo de desarrollar un consenso sobre la AC, que incorporó cuando así fue posible, información local que se adapte a la realidad de la región. El objetivo de este documento es mostrar los resultados de dicho trabajo. A través de metodología Delphi, se evaluaron, discutieron y votaron un total de 34 declaraciones o enunciados con respecto a aspectos relevantes de la AC

Searches for Ultra-High-Energy Photons at the Pierre Auger Observatory

The Pierre Auger Observatory, being the largest air-shower experiment in the world, offers an unprecedented exposure to neutral particles at the highest energies. Since the start of data taking more than 18 years ago, various searches for ultra-high-energy (UHE, $E\gtrsim10^{17}\,\text{eV}$) photons have been performed: either for a diffuse flux of UHE photons, for point sources of UHE photons or for UHE photons associated with transient events like gravitational wave events. In the present paper, we summarize these searches and review the current results obtained using the wealth of data collected by the Pierre Auger Observatory.Comment: Review article accepted for publication in Universe (special issue on ultra-high energy photons