Is It Safe to Perform Lung Surgery During the Coronavirus Pandemic?

Background: Coronavirus disease (COVID-19) patients are rapidly growing in our community. Patients with compromised lungs and older age are supposedly at high risk of poor outcomes with COVID-19. We aimed to evaluate the COVID-19 impact on lung surgery during this pandemic at our hospital. Methodology: This is a retrospective study of all lung surgery patients at our hospital in Boca Raton over three months (February to April 2020). All patients who remained for at least one-day inpatient post-lung surgery were assessed to see if they had an increased incidence of coronavirus infection during the hospital stay or at the follow-up office visit. Results: A total of 44 patients underwent thoracic surgery. It was found that there was no incidence of coronavirus infection in these patients. Conclusion: With adequate precautions, older patients can undergo lung surgery during this pandemic. There was no incidence of COVID-19 found among the patients during the hospital stay or at the first follow-up in the office. Also, the postoperative course was not adversely affected. Keywords: covid-19; lung cancer; lung surgery; thoracic surgery

Bile Leak following Laparoscopic Cholecystectomy due to Perforated Duodenal Ulcer in Patient with Roux-en-Y Gastric Bypass

Background and Aims. Screening for gastric diseases in symptomatic outpatients with conventional esophagogastroduodenoscopy (C-EGD) is expensive and has poor compliance. We aimed to explore the efficiency and safety of magnetic-controlled capsule gastroscopy (MCCG) in symptomatic outpatients who refused C-EGD. Methods. We performed a retrospective study of 76794 consecutive symptomatic outpatients from January 2014 to October 2019. A total of 2318 adults () in the MCCG group who refused C-EGD were matched with adults in the C-EGD group using propensity-score matching (PSM). The detection rates of abnormalities were analyzed to explore the application of MCCG in symptomatic patients. Results. Our study demonstrated a prevalence of gastric ulcers (GUs) in patients with functional dyspepsia- (FD-) like symptoms of 8.14%. The detection rate of esophagitis and Barrett’s esophagus was higher in patients with typical gastroesophageal reflux disease (GERD) symptoms than in patients in the other four groups (). The detection rates of gastric ulcers in the five groups (abdominal pain, bloating, heartburn, follow-up, and bleeding) were significantly different (). The total detection rate of gastric ulcers in symptomatic patients was 9.7%. A total of 7 advanced carcinomas were detected by MCCG and confirmed by endoscopic or surgical biopsy. The advanced gastric cancer detection rate was not significantly different between the MCCG group and the C-EGD matched group in terms of nonhematemesis GI bleeding (2 vs. 2, ). In addition, the overall focal lesion detection rate in the MCCG group was superior to that in the C-EGD matched group (224 vs. 184, ). MCCG gained a clinically meaningful small bowel diagnostic yield of 54.8% (17/31) out of 31 cases of suspected small bowel bleeding. No patient reported capsule retention at the two-week follow-up. Conclusion. MCCG is well tolerated, safe, and technically feasible and has a considerable diagnostic yield. The overall gastric diagnostic yield of gastric focal lesions with MCCG was comparable to that with C-EGD. MCCG offered a supplementary diagnosis in patients who had a previously undiagnostic C-EGD, indicating that MCCG could play an important role in the routine monitoring and follow-up of outpatient. MCCG shows its safety and efficiency in symptomatic outpatient applications

Analysing Sound Environment and Architectural Characteristics of Libraries through Indoor Soundscape Framework

This study presents the indoor soundscape framework in detail by describing the variables and factors that form an indoor soundscape study. The main objective is to introduce a new indoor soundscaping framework and systematically explain the variables that contribute to the overall evaluation of an indoor soundscape. Hence, the dependencies of physical and psychoacoustical factors of the sound environment and the spatial factors of the built entity are statistically tested. The new indoor soundscaping framework leads to an overarching evaluation perspective of enclosed sound environments, combining objective room acoustics research and noise control engineering with architectural analysis. Therefore, it is hypothesised that case spaces with certain plan organisations, volumetric relations, and spatial referencing lead to differentiated sound pressure level (SPL) and loudness (N) values. SPL and N parametric variances of the sound environments are discussed through the statistical findings with respect to the architectural characteristics of each library case space. The results show that the relation between crowd level variances and sound environment parametric values is statistically significant. It is also found that increasing the atrium height and atrium void volume, the atrium’s presence as a common architectural element, and its interpenetrating reference and domain containment results in unwanted variances and acoustic formations, leading to high SPL and N values

eSport – Phenomenon of a generation : the expanding market of the computer and video game industry in Europe

nicht vorhande

Serum Lipopolysaccharide-Binding Protein Concentrations in Trauma Victims

Background: In low concentrations, lipopolysaccharide-binding protein (LBP), an acute-phase protein recognizing lipopolysaccharide (LPS), catalyzes its transfer to the cellular receptor consisting of CD14 and Toll-like receptor-4. Previous studies have documented increased serum LBP concentrations in patients with sepsis, systemic inflammatory response syndrome (SIRS), or acute pancreatitis and after cardiopulmonary bypass. No prior studies have examined LBP expression in trauma victims. We hypothesized that admission LBP plasma concentrations are predictive of outcome (mortality) in trauma. This study assessed time-dependent changes in serum LBP concentrations in trauma patients soon after injury. Methods: A prospective, single-institution, observational cohort study of 121 adult trauma patients (age ≥17 years) with moderate to severe injury who required hospitalization. The trauma patients were male in 79.6% of the cases and had a mean age of 43.0 ± 20.6 years. The mean injury severity score (ISS) was 23 ± 12, and the crystalloid resuscitation volume given in the first 24 h averaged 6,640 ± 3,729 mL. Informed consent was obtained on admission, and blood samples were drawn on admission and at 24 h postadmission. Prospective data were collected for daily SIRS score, multiple organ dysfunction score (MODS), and sequential organ failure assessment (SOFA) score, complications, and outcomes. Plasma concentrations of LBP were measured by enzyme-linked immunosorbent assay. Results: Sixty patients (48.8% of the study cohort) required emergency surgical intervention and sustained a substantial intraoperative blood loss (mean 1,404 ± 2,757 mL). The hospital mortality rate was 16.3% (20 patients). The mean intensive care unit stay was 8.9 ± 16.4 days, and the hospital stay was 14.8 ± 19.6 days. The patients had a significantly higher serum concentrations of LBP on admission (mean 28.0 ± 25.3 mg/L; range 2–100 mg/L) than did control subjects (mean 6.2 ± 2.1 mg/L; range 1.3–12.8 mg/L; p < 0.01), similar to the plasma concentrations previously reported in septic patients. A significant increase in LBP concentration was noted at 24 h (mean 72.3 ± 45.7 mg/L; range 8–210 mg/L; p < 0.05). The admission LBP concentration was significantly greater in nonsurvivors than in survivors. However, after controlling for age and ISS, the admission LBP concentration did not predict death.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/63423/1/sur.2006.7.251.pd

Operational characteristics of the superconducting high flux plasma generator Magnum-PSI

\u3cp\u3eThe interaction of intense plasma impacting on the wall of a fusion reactor is an area of high and increasing importance in the development of electricity production from nuclear fusion. In the Magnum-PSI linear device, an axial magnetic field confines a high density, low temperature plasma produced by a wall stabilized DC cascaded arc into an intense magnetized plasma beam directed onto a target. The experiment has shown its capability to reach conditions that enable fundamental studies of plasma-surface interactions in the regime relevant for fusion reactors such as ITER: 10\u3csup\u3e23\u3c/sup\u3e–10\u3csup\u3e25\u3c/sup\u3e m\u3csup\u3e−2\u3c/sup\u3es\u3csup\u3e−1\u3c/sup\u3e hydrogen plasma flux densities at 1–5 eV for tens of seconds by using conventional electromagnets. Recently the machine was upgraded with a superconducting magnet, enabling steady-state magnetic fields up to 2.5 T, expanding the operational space to high fluence capabilities for the first time. Also the diagnostic suite has been expanded by a new 4-channel resistive bolometer array and ion beam analysis techniques for surface analysis after plasma exposure of the target. A novel collective Thomson scattering system has been developed and will be implemented on Magnum-PSI. In this contribution, the current status, capabilities and performance of Magnum-PSI are presented.\u3c/p\u3