Cáncer de cuello uterino en las mujeres del municipio de San José del Guaviare

El cáncer de cuello uterino es un tipo de cáncer que se origina en la parte inferior del útero, la mayoría de los casos de cáncer de cuello uterino son causados por el virus del papiloma humano (VPH) y generalmente se desarrollan lentamente. Con esta propuesta se busca implementar estrategias para disminuir la tasa de mortalidad de cáncer de cuello uterino en las mujeres del municipio de San José del Guaviare. Para garantizar el proyecto se tiene previsto la aprobación y colaboración por parte de la alcaldía municipal, secretaria de salud y el Hospital de San José de Guaviare. El objetivo de este estudio es describir las diferentes actividades creadas para la promoción de la salud y prevención de la enfermedad. En el municipio de San José de Guaviare presenta una de las tasas manas altas del departamento de Guaviare y a nivel Nacional de 12,89 por 100.000 habitantes Se implementan estrategias para reducir la tasa de mortalidad de cáncer de cuello uterino mediante charlas educativas, canalización de mujeres de 25 a 69 años para la realización de exámenes de detección temprana como la citología y prueba de VPH, también la vacunación a todas la niñas de 9 a 17 años, con la vacuna tetravalente contra el VPH y educar a los padres en la importancia de la administración de esta vacuna ya que es más efectiva administrarla en este periodo de vida porque aún no están en contacto con el virus. La base de esta investigación se responde mediante el (ASIS) Análisis de Situación de Salud del municipio y las metas propuestas del plan decenal de salud pública 2022-2031, en busca de establecer una red de información acerca de la prevención y detección temprana del cáncer de cuello uterino en la población de las mujeres del San José del Guaviare y lograr disminuir la tasa de mortalidad garantizando la mejor calidad de vida a las habitantes del municipio.Cervical cancer is a type of cancer that originates in the lower part of the uterus, most cases of cervical cancer are caused by the human papillomavirus (HPV) and usually develops slowly. This proposal seeks to implement strategies to reduce the mortality rate of cervical cancer in women in the municipality of San José del Guaviare. To guarantee the project, the approval and collaboration of the municipal mayor's office, the health secretary and the San José de Guaviare Hospital are expected. The objective of this study is to describe the different activities created for the promotion of health and disease prevention. In the municipality of San José de Guaviare, it has one of the highest rates in the department of Guaviare and at a national level of 12.89 per 100,000 inhabitants. Strategies are implemented to reduce the mortality rate of cervical cancer through educational talks, channeling of women from 25 to 69 years of age to carry out early detection tests such as cytology and HPV testing, as well as vaccination of all girls from 9 to 17 years of age with the quadrivalent HPV vaccine and educate parents on the importance of the administration of this vaccine since it is more effective to administer it in this period of life because they are not yet in contact with the virus The basis of this research is answered through the (ASIS) Health Situation Analysis of the municipality and the proposed goals of the ten-year public health plan 2022-2031, seeking to establish an information network about the prevention and early detection of cancer of the cervix in the population of women from San José del Guaviare and to reduce the mortality rate, guaranteeing the best quality of life for the inhabitants of the municipality

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Search for supersymmetry in events with one lepton and multiple jets in proton-proton collisions at root s=13 TeV

Peer reviewe

Search for anomalous couplings in boosted WW/WZ -> l nu q(q)over-bar production in proton-proton collisions at root s=8TeV

Peer reviewe

Colombian consensus recommendations for diagnosis, management and treatment of the infection by SARS-COV-2/ COVID-19 in health care facilities - Recommendations from expert´s group based and informed on evidence

La Asociación Colombiana de Infectología (ACIN) y el Instituto de Evaluación de Nuevas Tecnologías de la Salud (IETS) conformó un grupo de trabajo para desarrollar recomendaciones informadas y basadas en evidencia, por consenso de expertos para la atención, diagnóstico y manejo de casos de Covid 19. Estas guías son dirigidas al personal de salud y buscar dar recomendaciones en los ámbitos de la atención en salud de los casos de Covid-19, en el contexto nacional de Colombia

Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial.

BACKGROUND: Remote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown to reduce myocardial infarct size in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). We investigated whether remote ischaemic conditioning could reduce the incidence of cardiac death and hospitalisation for heart failure at 12 months. METHODS: We did an international investigator-initiated, prospective, single-blind, randomised controlled trial (CONDI-2/ERIC-PPCI) at 33 centres across the UK, Denmark, Spain, and Serbia. Patients (age >18 years) with suspected STEMI and who were eligible for PPCI were randomly allocated (1:1, stratified by centre with a permuted block method) to receive standard treatment (including a sham simulated remote ischaemic conditioning intervention at UK sites only) or remote ischaemic conditioning treatment (intermittent ischaemia and reperfusion applied to the arm through four cycles of 5-min inflation and 5-min deflation of an automated cuff device) before PPCI. Investigators responsible for data collection and outcome assessment were masked to treatment allocation. The primary combined endpoint was cardiac death or hospitalisation for heart failure at 12 months in the intention-to-treat population. This trial is registered with ClinicalTrials.gov (NCT02342522) and is completed. FINDINGS: Between Nov 6, 2013, and March 31, 2018, 5401 patients were randomly allocated to either the control group (n=2701) or the remote ischaemic conditioning group (n=2700). After exclusion of patients upon hospital arrival or loss to follow-up, 2569 patients in the control group and 2546 in the intervention group were included in the intention-to-treat analysis. At 12 months post-PPCI, the Kaplan-Meier-estimated frequencies of cardiac death or hospitalisation for heart failure (the primary endpoint) were 220 (8·6%) patients in the control group and 239 (9·4%) in the remote ischaemic conditioning group (hazard ratio 1·10 [95% CI 0·91-1·32], p=0·32 for intervention versus control). No important unexpected adverse events or side effects of remote ischaemic conditioning were observed. INTERPRETATION: Remote ischaemic conditioning does not improve clinical outcomes (cardiac death or hospitalisation for heart failure) at 12 months in patients with STEMI undergoing PPCI. FUNDING: British Heart Foundation, University College London Hospitals/University College London Biomedical Research Centre, Danish Innovation Foundation, Novo Nordisk Foundation, TrygFonden

Search for new phenomena in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum in pp collisions at √s=13 TeV

Search results are presented for physics beyond the standard model in final states with two opposite-charge, same-flavor leptons, jets, and missing transverse momentum. The data sample corresponds to an integrated luminosity of 35.9 fb−1 of proton-proton collisions at s√=13 TeV collected with the CMS detector at the LHC in 2016. The analysis uses the invariant mass of the lepton pair, searching for a kinematic edge or a resonant-like excess compatible with the Z boson mass. The search for a kinematic edge targets production of particles sensitive to the strong force, while the resonance search targets both strongly and electroweakly produced new physics. The observed yields are consistent with the expectations from the standard model, and the results are interpreted in the context of simplified models of supersymmetry. In a gauge mediated supersymmetry breaking (GMSB) model of gluino pair production with decay chains including Z bosons, gluino masses up to 1500–1770 GeV are excluded at the 95% confidence level depending on the lightest neutralino mass. In a model of electroweak chargino-neutralino production, chargino masses as high as 610 GeV are excluded when the lightest neutralino is massless. In GMSB models of electroweak neutralino-neutralino production, neutralino masses up to 500-650 GeV are excluded depending on the decay mode assumed. Finally, in a model with bottom squark pair production and decay chains resulting in a kinematic edge in the dilepton invariant mass distribution, bottom squark masses up to 980–1200 GeV are excluded depending on the mass of the next-to-lightest neutralino

Search for electroweak production of charginos and neutralinos in multilepton final states in proton-proton collisions at root s=13 TeV

Results are presented from a search for the direct electroweak production of charginos and neutralinos in signatures with either two or more leptons (electrons or muons) of the same electric charge, or with three or more leptons, which can include up to two hadronically decaying tau leptons. The results are based on a sample of protonproton collision data collected at p s = 13TeV, recorded with the CMS detector at the LHC, corresponding to an integrated luminosity of 35.9 fb1. The observed event yields are consistent with the expectations based on the standard model. The results are interpreted in simpli ed models of supersymmetry describing various scenarios for the production and decay of charginos and neutralinos. Depending on the model parameters chosen, mass values between 180GeV and 1150 GeV are excluded at 95% CL. These results signi cantly extend the parameter space probed for these particles in searches at the LHC. In addition, results are presented in a form suitable for alternative theoretical interpretations.Sponsoring Consortium for Open Access Publishing in Particle Physic

Caracterización sociodemográfica de cuidadores de niños en situación de discapacidad del Instituto Técnico Guaimaral en San José de Cúcuta

Objective To make a socio-demographical characterization of family caregivers of children in situation of chronic disabling disease, from Instituto Tecnico Guaimaral during the second semester of 2013. Methodology A descriptive, transversal and quantitative approach was conducted. The study included 264 caregivers who were selected by non-probalistic sampling. After verifying the compliance of the inclusive criteria, the caregivers were applied the instrument: Characterization of caregivers of people with chronic diseases. Results 94,2% were female, aged between 36 and 59 years (61,4%), married (48,1%) and housewives (72,7%) with incomplete high school (32,2%). A significant percentage of caregivers had been playing their role since the time of diagnosis of the disease (83,0%), 89,0% of the sample had an experience of more than three years and 95,9% spent more than 7 hours in their care activity. Conclusion The findings of the study are consistent with data reported in previous studies and pointed out in the literature by other authors, where the c graphic variables studied determine a similar profile of the caregiver.Objetiv Realizar una caracterización socio-demográfica de los cuidadores familiares de niños en situación de enfermedad crónica discapacitante del Instituto Técnico Guaimaral durante el segundo semestre del 2013. Metodología Se realizó un estudio con abordaje cuantitativo, de tipo descriptivo transversal. Fueron seleccionados mediante muestreo no probabilístico 264 cuidadores a quienes, verificado el cumplimiento de criterios de inclusión, se les aplicó el instrumento denominado:Caracterización de cuidadores de enfermos crónicos. Resultados El 94,2% eran mujeres, con edades comprendidas entre los 36 y 59 años (61,4%); casados (48,1%), amas de casa (72,7%) y con bachillerato incompleto (32,2%). Un porcentaje significativo de los cuidadores venía desempeñando su rol desde el momento del diagnóstico de la enfermedad (83,0%), el 89,0% tenía una experiencia de más de tres años y el 95,9% con dedicación mayor de 7 horas a su actividad de cuidado. Conclusión Los resultados son acordes con los datos reportados en estudios previos y lo señalado en la bibliografía por otros autores donde la mográficas estudiadas determinan un perfil similar del cuidador

Caracterización sociodemográfica de cuidadores de niños en situación de discapacidad del Instituto Tecnológico Guaimaral en San Jose de Cúcuta

El 94,2% eran mujeres, con edades comprendidas entre los 36 y 59 años (61,4%); casados (48,1%), amas de casa (72,7%) y con bachillerato incompleto (32,2%). Un porcentaje significativo de los cuidadores venía desempeñando su rol desde el momento del diagnóstico de la enfermedad (83,0%), el 89,0% tenía una experiencia de más de tres años y el 95,9% con dedicación mayor de 7 horas a su actividad de cuidado.Realizar una caracterización socio-demográfica de los cuidadores familiares de niños en situación de enfermedad crónica discapacitante del Instituto Técnico Guaimaral durante el segundo semestre del 2013. Metodología: Se realizó un estudio con abordaje cuantitativo, de tipo descriptivo transversal. Fueron seleccionados mediante muestreo no probabilístico 264 cuidadores a quienes, verificado el cumplimiento de criterios de inclusión, se les aplicó el instrumento denominado: Caracterización de cuidadores de enfermos crónicos. Abstract To make a socio-demographical characterization of family caregivers of children in situation of chronic disabling disease, from Instituto Tecnico Guaimaral during the second semester of 2013. Methodology: A descriptive, transversal and quantitative approach was conducted. The study included 264 caregivers who were selected by non-probalistic sampling. After verifying the compliance of the inclusive criteria, the caregivers were applied the instrument: Characterization of caregivers of people with chronic diseases.Universidad Libre Seccional Pereir