Avaliação da eficácia da psicoterapia on-line versus presencial no tratamento de transtornos de humor

Na intricada teia dos transtornos do humor, onde milhões enfrentam desafios globais, a depressão e o transtorno bipolar se destacam, demandando compreensão profunda e estratégias personalizadas. A persistente tristeza e os episódios extremos de humor, permeados por fatores externos, tornam o diagnóstico e tratamento essenciais, reverberando não só no indivíduo, mas nas redes sociais. Psicoterapia, presencial ou on-line, emerge como um componente crucial, oferecendo um espaço seguro e conveniência. Trata-se de uma pesquisa cujo estudo foi objetivo avaliar a avaliação da eficácia das psicoterapias on-line e presencial no tratamento de transtornos de humor. Para isso, se realizou uma revisão sistemática de literatura utilizando as bases de dados Medical Literature Analysis and Retrieval System On-line (MEDLINE), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Scientific Electronic Library On-line (SCIELO). Após análise e interpretação qualitativa dos resultados, concluiu-se que a psicoterapia on-line, especialmente a Terapia Cognitivo-Comportamental online (eTCC), apresentou maior eficácia no tratamento de transtornos de humor, enfatizando a ansiedade, em comparação com abordagens presenciais. A evidência consistente de uma redução nos sintomas ansiosos em diversos grupos de pacientes e condições clínicas ressaltou os benefícios dessa modalidade, incluindo a redução de custos sociais e econômicos, maior alcance clínico e melhorias globais nos sintomas

Supplement: "Localization and broadband follow-up of the gravitational-wave transient GW150914" (2016, ApJL, 826, L13)

This Supplement provides supporting material for Abbott et al. (2016a). We briefly summarize past electromagnetic (EM) follow-up efforts as well as the organization and policy of the current EM follow-up program. We compare the four probability sky maps produced for the gravitational-wave transient GW150914, and provide additional details of the EM follow-up observations that were performed in the different bands

Localization and broadband follow-up of the gravitational-wave transient GW150914

A gravitational-wave (GW) transient was identified in data recorded by the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) detectors on 2015 September 14. The event, initially designated G184098 and later given the name GW150914, is described in detail elsewhere. By prior arrangement, preliminary estimates of the time, significance, and sky location of the event were shared with 63 teams of observers covering radio, optical, near-infrared, X-ray, and gamma-ray wavelengths with ground- and space-based facilities. In this Letter we describe the low-latency analysis of the GW data and present the sky localization of the first observed compact binary merger. We summarize the follow-up observations reported by 25 teams via private Gamma-ray Coordinates Network circulars, giving an overview of the participating facilities, the GW sky localization coverage, the timeline, and depth of the observations. As this event turned out to be a binary black hole merger, there is little expectation of a detectable electromagnetic (EM) signature. Nevertheless, this first broadband campaign to search for a counterpart of an Advanced LIGO source represents a milestone and highlights the broad capabilities of the transient astronomy community and the observing strategies that have been developed to pursue neutron star binary merger events. Detailed investigations of the EM data and results of the EM follow-up campaign are being disseminated in papers by the individual teams

Comparative effectiveness of autologous hematopoietic stem cell transplant vs fingolimod, natalizumab, and ocrelizumab in highly active relapsing-remitting multiple sclerosis

Importance: Autologous hematopoietic stem cell transplant (AHSCT) is available for treatment of highly active multiple sclerosis (MS). Objective: To compare the effectiveness of AHSCT vs fingolimod, natalizumab, and ocrelizumab in relapsing-remitting MS by emulating pairwise trials. Design, Setting, and Participants: This comparative treatment effectiveness study included 6 specialist MS centers with AHSCT programs and international MSBase registry between 2006 and 2021. The study included patients with relapsing-remitting MS treated with AHSCT, fingolimod, natalizumab, or ocrelizumab with 2 or more years study follow-up including 2 or more disability assessments. Patients were matched on a propensity score derived from clinical and demographic characteristics. Exposure: AHSCT vs fingolimod, natalizumab, or ocrelizumab. Main outcomes: Pairwise-censored groups were compared on annualized relapse rates (ARR) and freedom from relapses and 6-month confirmed Expanded Disability Status Scale (EDSS) score worsening and improvement. Results: Of 4915 individuals, 167 were treated with AHSCT; 2558, fingolimod; 1490, natalizumab; and 700, ocrelizumab. The prematch AHSCT cohort was younger and with greater disability than the fingolimod, natalizumab, and ocrelizumab cohorts; the matched groups were closely aligned. The proportion of women ranged from 65% to 70%, and the mean (SD) age ranged from 35.3 (9.4) to 37.1 (10.6) years. The mean (SD) disease duration ranged from 7.9 (5.6) to 8.7 (5.4) years, EDSS score ranged from 3.5 (1.6) to 3.9 (1.9), and frequency of relapses ranged from 0.77 (0.94) to 0.86 (0.89) in the preceding year. Compared with the fingolimod group (769 [30.0%]), AHSCT (144 [86.2%]) was associated with fewer relapses (ARR: mean [SD], 0.09 [0.30] vs 0.20 [0.44]), similar risk of disability worsening (hazard ratio [HR], 1.70; 95% CI, 0.91-3.17), and higher chance of disability improvement (HR, 2.70; 95% CI, 1.71-4.26) over 5 years. Compared with natalizumab (730 [49.0%]), AHSCT (146 [87.4%]) was associated with marginally lower ARR (mean [SD], 0.08 [0.31] vs 0.10 [0.34]), similar risk of disability worsening (HR, 1.06; 95% CI, 0.54-2.09), and higher chance of disability improvement (HR, 2.68; 95% CI, 1.72-4.18) over 5 years. AHSCT (110 [65.9%]) and ocrelizumab (343 [49.0%]) were associated with similar ARR (mean [SD], 0.09 [0.34] vs 0.06 [0.32]), disability worsening (HR, 1.77; 95% CI, 0.61-5.08), and disability improvement (HR, 1.37; 95% CI, 0.66-2.82) over 3 years. AHSCT-related mortality occurred in 1 of 159 patients (0.6%). Conclusion: In this study, the association of AHSCT with preventing relapses and facilitating recovery from disability was considerably superior to fingolimod and marginally superior to natalizumab. This study did not find evidence for difference in the effectiveness of AHSCT and ocrelizumab over a shorter available follow-up time

Localization and Broadband Follow-up of the Gravitational-wave Transient GW150914

A gravitational-wave (GW) transient was identified in data recorded by the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) detectors on 2015 September 14. The event, initially designated G184098 and later given the name GW150914, is described in detail elsewhere. By prior arrangement, preliminary estimates of the time, significance, and sky location of the event were shared with 63 teams of observers covering radio, optical, near-infrared, X-ray, and gamma-ray wavelengths with ground- and space-based facilities. In this Letter we describe the low-latency analysis of the GW data and present the sky localization of the first observed compact binary merger. We summarize the follow-up observations reported by 25 teams via private Gamma-ray Coordinates Network circulars, giving an overview of the participating facilities, the GW sky localization coverage, the timeline, and depth of the observations. As this event turned out to be a binary black hole merger, there is little expectation of a detectable electromagnetic (EM) signature. Nevertheless, this first broadband campaign to search for a counterpart of an Advanced LIGO source represents a milestone and highlights the broad capabilities of the transient astronomy community and the observing strategies that have been developed to pursue neutron star binary merger events. Detailed investigations of the EM data and results of the EM follow-up campaign are being disseminated in papers by the individual teams. </p

Localization and broadband follow-up of the gravitational-wave transient GW150914

A gravitational-wave transient was identified in data recorded by the Advanced LIGO detectors on 2015 September 14. The event candidate, initially designated G184098 and later given the name GW150914, is described in detail elsewhere. By prior arrangement, preliminary estimates of the time, significance, and sky location of the event were shared with 63 teams of observers covering radio, optical, near-infrared, X-ray, and gamma-ray wavelengths with ground- and space-based facilities. In this Letter we describe the low-latency analysis of the gravitational wave data and present the sky localization of the first observed compact binary merger. We summarize the follow-up observations reported by 25 teams via private Gamma-ray Coordinates Network Circulars, giving an overview of the participating facilities, the gravitational wave sky localization coverage, the timeline and depth of the observations. As this event turned out to be a binary black hole merger, there is little expectation of a detectable electromagnetic signature. Nevertheless, this first broadband campaign to search for a counterpart of an Advanced LIGO source represents a milestone and highlights the broad capabilities of the transient astronomy community and the observing strategies that have been developed to pursue neutron star binary merger events. Detailed investigations of the electromagnetic data and results of the electromagnetic follow-up campaign will be disseminated in the papers of the individual teams

EFEITOS DA QUEIMA DE RESÍDUOS DO SOLO SOB ATRIBUTOS QUÍMICOS DE UM LATOSSOLO VERMELHO DISTRÓFICO DO CERRADO

O fogo é um instrumento de manejo em diversos tipos de ecossistemas, já que atua como importante agente mineralizador do solo. O objetivo deste trabalho foi comparar ocomparar o efeito da queima de resíduos sobre as propriedades quimicas do Latossolo vermelho distrófico do Cerrado. O ambiente estudado foi uma lavoura de milho, sendo composta de quatro sistemas de manejo: manejo sem queima de resíduos não revolvimento do solo (SSQNR) e manejo sem queima e revolvimento do solo (SSQR); manejo com queima de resíduos não revolvimento do solo (SCQNR) e queima de resíduos com revolvimento do solo (SCQR). Para a determinação dos atributos químicos, o teor de carbono orgânico e matéria orgânica do solo, foram coletadas amostras de solo na profundidade de 0,0-0,05 e de 0,10-0,20 m. Não houve interação entre os tipos de manejo de solo para os nutrientes K, Al, Ca, Mg, para as relações Ca+Mg, H+Al, matéria orgânica (MO), carbono orgânico (CO) e saturação por Al (m%) em função da queima, houve diferença significativa, entre as camadas do solo para os teores de MO, K, Ca, Mg, Al, Ca+Mg e CO (Tukey, 5%).Palavras-chave: queimada, fertilidade do solo, manejo cultural. EFFECTS OF FIRE IN CHEMICAL ATTRIBUTES OF A RED LATOSOL CERRADO DYSTROPHICABSTRACTFire is a management tool for various types of ecosystems, it acts as an important soil mineralization agent. The objective of this study was to compare the effect of burning under the ground in two areas of cultivation. The study setting was a corn crop, consisting of four management systems: soil without revolved not burning (SSQNR) and upturned soil without burning (SSQR); a soil with no upturned burning (SCQNR) and an upturned soil with burning (SCQR). To determine the chemical properties, organic carbon content and soil organic matter, soil samples were collected in depth from 0.0-0.05 and 0.10-0.20 m. There was no interaction between the types of soil management for nutrients K, Al, Ca, Mg, Ca + Mg for relationships, H + Al, MO, CO and Al saturation (m%). As a function of burning, there was significant difference when used the Tukey test at 5% probability relative depth to the organic matter, K, Ca, Mg, Al, Ca + Mg and CO.Keywords: burned, soil fertility, cultural management. DOI: http://dx.doi.org/10.14583/2318-7670.v04n04a0