Composite carbon materials from winery composted waste for the treatment of effluents contaminated with ketoprofen and 2-nitrophenol

The present work consisted of preparing and characterizing composite carbon materials (WRCC) from raw winery residues (WR) activated with zinc chloride to produce a carbon adsorbent. The WRCC was used for the adsorption of emerging contaminants in aqueous media. The WRCC presented a morphology with favorable characteristics for the adsorption process, giving an abundant porous structure with pores of different sizes. The results show the WRCC's effectiveness, presenting surface area values (227 m2 g-1) and total pore volume (0.175 cm3 g-1). The general order kinetic model predicted the experimental curves sufficiently. The Sips model better described the two adsorbates' equilibrium data, with maximum adsorption capacities of 376.0 and 119.6 mg g-1 for 2-nitrophenol and ketoprofen, respectively. The WRCC carbon material was also highly efficient, with maximum removal of 81.4% and 94% in 1000 mg L-1 of the compounds 2-nitrophenol and ketoprofen. Finally, the prepared material has essential characteristics that make it an efficient adsorbent in treating effluents with emerging contaminants

Digit Ratio Predicts Sense of Direction in Women

The relative length of the second-to-fourth digits (2D:4D) has been linked with prenatal androgen in humans. The 2D:4D is sexually dimorphic, with lower values in males than females, and appears to correlate with diverse measures of behavior. However, the relationship between digit ratio and cognition, and spatial cognition in particular, has produced mixed results. In the present study, we hypothesized that spatial tasks separating cue conditions that either favored female or male strategies would examine this structure-function correlation with greater precision. Previous work suggests that males are better in the use of directional cues than females. In the present study, participants learned a target location in a virtual landscape environment, in conditions that contained either all directional (i.e., distant or compass bearing) cues, or all positional (i.e., local, small objects) cues. After a short delay, participants navigated back to the target location from a novel starting location. Males had higher accuracy in initial search direction than females in environments with all directional cues. Lower digit ratio was correlated with higher accuracy of initial search direction in females in environments with all directional cues. Mental rotation scores did not correlate with digit ratio in either males or females. These results demonstrate for the first time that a sex difference in the use of directional cues, i.e., the sense of direction, is associated with more male-like digit ratio.National Science Foundation (U.S.) (NSF ECCS-1028319)National Science Foundation (U.S.) (NSF Graduate Student Fellowship)Mary Elisabeth Rennie Endowment for Epilepsy Researc

Scopolamine Administration Modulates Muscarinic, Nicotinic and NMDA Receptor Systems

Studies on the effect of scopolamine on memory are abundant but so far only regulation of the muscarinic receptor (M1) has been reported. We hypothesized that levels of other cholinergic brain receptors as the nicotinic receptors and the N-methyl-D-aspartate (NMDA) receptor, known to be involved in memory formation, would be modified by scopolamine administration

Ubiquitous molecular substrates for associative learning and activity-dependent neuronal facilitation.

Recent evidence suggests that many of the molecular cascades and substrates that contribute to learning-related forms of neuronal plasticity may be conserved across ostensibly disparate model systems. Notably, the facilitation of neuronal excitability and synaptic transmission that contribute to associative learning in Aplysia and Hermissenda, as well as associative LTP in hippocampal CA1 cells, all require (or are enhanced by) the convergence of a transient elevation in intracellular Ca2+ with transmitter binding to metabotropic cell-surface receptors. This temporal convergence of Ca2+ and G-protein-stimulated second-messenger cascades synergistically stimulates several classes of serine/threonine protein kinases, which in turn modulate receptor function or cell excitability through the phosphorylation of ion channels. We present a summary of the biophysical and molecular constituents of neuronal and synaptic facilitation in each of these three model systems. Although specific components of the underlying molecular cascades differ across these three systems, fundamental aspects of these cascades are widely conserved, leading to the conclusion that the conceptual semblance of these superficially disparate systems is far greater than is generally acknowledged. We suggest that the elucidation of mechanistic similarities between different systems will ultimately fulfill the goal of the model systems approach, that is, the description of critical and ubiquitous features of neuronal and synaptic events that contribute to memory induction

Colonial lives of the carceral archipelago: rethinking the neoliberal security state

Mass incarceration, police brutality, and border controls are part and parcel of the everyday experiences of marginalized and racialized communities across the world. Recent scholarship in international relations, sociology, and geography has examined the prevalence of these coercive practices through the prism of “disciplinary,” “penal,” or “authoritarian” neoliberalism. In this collective discussion, we argue that although this literature has brought to the fore neoliberalism's reliance on state violence, it has yet to interrogate how these carceral measures are linked to previous forms of global racial ordering. To rectify this moment of “colonial unknowing,” the collective discussion draws on decolonial approaches, Indigenous studies, and theories of racial capitalism. It demonstrates that “new” and “neoliberal” forms of domestic control must be situated within the global longue durée of racialized and colonial accumulation by dispossession. By mapping contemporary modes of policing, incarceration, migration control, and surveillance onto earlier forms of racial–colonial subjugation, we argue that countering the violence of neoliberalism requires more than nostalgic appeals for a return to Keynesianism. What is needed is abolition—not just of the carceral archipelago, but of the very system of racial capitalism that produces and depends on these global vectors of organized violence and abandonment. L'incarcération de masse, la brutalité policière et les contrôles aux frontières constituent une partie intégrante des expériences quotidiennes des communautés marginalisées et racialisées du monde entier. Des études récentes en relations internationales, en sociologie et en géographie ont examiné la prévalence de ces pratiques coercitives par le prisme du néolibéralisme « disciplinaire », « pénal » ou « autoritaire ». Dans cet article, nous soutenons que bien que cette littérature ait mis en évidence la dépendance du néolibéralisme à la violence étatique, elle ne s'est pas encore interrogée sur le lien entre ces mesures carcérales et les formes précédentes d'ordre racial mondial. Cet article s'appuie sur le féminisme noir, les approches décoloniales, les études indigènes et les théories de capitalisme racial pour rectifier cette « ignorance coloniale » marquante. Il démontre que les formes « nouvelles » et « néolibérales » de contrôle national doivent se situer dans la longue durée globale de l'accumulation racialisée et coloniale par dépossession. Nous associons les modes contemporains de maintien de l'ordre, d'incarcération, de contrôle migratoire et de surveillance à des formes antérieures d'assujettissement racial/colonial pour soutenir que contrer la violence du néolibéralisme exige davantage que des appels nostalgiques au retour du keynésianisme. Ce qu'il faut, c'est une abolition : non seulement de l'archipel carcéral, mais aussi du système de capitalisme racial en lui-même qui produit et dépend de ces vecteurs globaux de violence organisée et d'abandon. El encarcelamiento masivo, la brutalidad policial y los controles fronterizos forman parte de las experiencias cotidianas de las comunidades marginadas y racializadas de todo el mundo. Estudios recientes en RI, Sociología y Geografía han examinado la prevalencia de estas prácticas coercitivas a través del prisma del neoliberalismo “disciplinario,” “penal” o “autoritario.” En este artículo, sostenemos que, si bien esta literatura puso en primer plano la dependencia del neoliberalismo de la violencia estatal, aún tiene que cuestionar la manera en que estas medidas carcelarias se vinculan a formas anteriores de ordenamiento racial global. Para rectificar este momento de “desconocimiento colonial,” el artículo recurre al feminismo negro, a los abordajes descoloniales, a los estudios indígenas y a las teorías del capitalismo racial. Demuestra que las formas “nuevas” y “neoliberales” de control interno se deben situar dentro de la longue durée global de la acumulación por desposesión racializada y colonial. Al trazar un mapa de los modos contemporáneos de vigilancia policial, encarcelamiento, control de la migración y vigilancia sobre las formas anteriores de subyugación racial-colonial, sostenemos que contrarrestar la violencia del neoliberalismo requiere algo más que apelaciones nostálgicas de retorno al keynesianismo. Lo que se necesita es la abolición, no solo del archipiélago carcelario, sino también del propio sistema de capitalismo racial que produce y depende de estos vectores globales de violencia y abandono organizados

Evolutionary origins of human handedness : evaluating contrasting hypotheses

Variation in methods and measures, resulting in past dispute over the existence of population handedness in nonhuman great apes, has impeded progress into the origins of human right-handedness and how it relates to the human hallmark of language. Pooling evidence from behavioral studies, neuroimaging and neuroanatomy, we evaluate data on manual and cerebral laterality in humans and other apes engaged in a range of manipulative tasks and in gestural communication. A simplistic human/animal partition is no longer tenable, and we review four (nonexclusive) possible drivers for the origin of population-level right-handedness: skilled manipulative activity, as in tool use; communicative gestures; organizational complexity of action, in particular hierarchical structure; and the role of intentionality in goal-directed action. Fully testing these hypotheses will require developmental and evolutionary evidence as well as modern neuroimaging data.Publisher PDFPeer reviewe