319 research outputs found

    Five years on: research, development and changing practice

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    Impact of intrauterine growth restriction on cerebral and renal oxygenation and perfusion during the first 3 days after birth

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    Intrauterine growth restriction (IUGR) is associated with a higher incidence of perinatal complications as well as cardiovascular and renal diseases later on. A better insight into the disease mechanisms underlying these sequalae is important in order to identify which IUGR infants are at a higher risk and find strategies to improve their outcome. In this prospective case–control study we examined whether IUGR had any effect on renal and cerebral perfusion and oxygen saturation in term neonates. We integrated near-infrared spectroscopy (NIRS), echocardiographic, Doppler and renal function data of 105 IUGR infants and 105 age/gender-matched controls. Cerebral and renal regional oxygen saturation values were measured by NIRS during the first 12 h after birth. Echocardiography alongside Doppler assessment of renal and anterior cerebral arteries were performed at 6, 24, 48 and 72 h of age. Glomerular and tubular functions were also assessed. We found a left ventricular dysfunction together with a higher cerebral oxygen saturation and perfusion values in the IUGR group. IUGR term infants showed a higher renal oxygen saturation and a reduced oxygen extraction together with a subclinical renal damage, as indicated by higher values of urinary neutrophil gelatinase-associated lipocalin and microalbumin. These data suggest that some of the haemodynamic changes present in growth-restricted foetuses may persist postnatally. The increased cerebral oxygenation may suggest an impaired transition to normal autoregulation as a consequence of intra-uterine chronic hypoxia. The higher renal oxygenation may reflect a reduced renal oxygen consumption due to a subclinical kidney damage

    Essentially Optimal Robust Secret Sharing with Maximal Corruptions

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    In a tt-out-of-nn robust secret sharing scheme, a secret message is shared among nn parties who can reconstruct the message by combining their shares. An adversary can adaptively corrupt up to tt of the parties, get their shares, and modify them arbitrarily. The scheme should satisfy privacy, meaning that the adversary cannot learn anything about the shared message, and robustness, meaning that the adversary cannot cause the reconstruction procedure to output an incorrect message. Such schemes are only possible in the case of an honest majority, and here we focus on unconditional security in the maximal corruption setting where n=2t+1n = 2t+1. In this scenario, to share an mm-bit message with a reconstruction failure probability of at most 2−k2^{-k}, a known lower-bound shows that the share size must be at least m+km + k bits. On the other hand, all prior constructions have share size that scales linearly with the number of parties nn, and the prior state-of-the-art scheme due to Cevallos et al. (EUROCRYPT \u2712) achieves m+O~(k+n)m + \widetilde{O}(k + n). In this work, we construct the first robust secret sharing scheme in the maximal corruption setting with n=2t+1n=2t+1, that avoids the linear dependence between share size and the number of parties nn. In particular, we get a share size of only m+O~(k)m + \widetilde{O}(k) bits. Our scheme is computationally efficient and relies on approximation algorithms for the minimum graph bisection problem

    Nearly Optimal Robust Secret Sharing against Rushing Adversaries

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    Robust secret sharing is a strengthening of standard secret sharing that allows the shared secret to be recovered even if some of the shares being used in the reconstruction have been adversarially modified. In this work, we study the setting where out of all the nn shares, the adversary is allowed to adaptively corrupt and modify tt shares, where n=2t+1n = 2t+1. Further, we deal with \textit{rushing} adversaries, meaning that the adversary is allowed to see the honest parties\u27 shares before modifying its own shares. It is known that when n=2t+1n = 2t+1, to share a secret of length mm bits and recover it with error less than 2−sec⁥2^{-\sec}, shares of size at least m+sec⁥m+\sec bits are needed. Recently, Bishop, Pastro, Rajaraman, and Wichs (EUROCRYPT 2016) constructed a robust secret sharing scheme with shares of size m+O(sec⁡⋅polylog(n,m,sec⁥))m + O(\sec\cdot\textrm{polylog}(n,m,\sec)) bits that is secure in this setting against non-rushing adversaries. Later, Fehr and Yuan (EUROCRYPT 2019) constructed a scheme that is secure against rushing adversaries, but has shares of size m+O(sec⁡⋅nϔ⋅polylog(n,m,sec⁥))m + O(\sec\cdot n^{\epsilon}\cdot \textrm{polylog}(n,m,\sec)) bits for an arbitrary constant Ï”>0\epsilon > 0. They also showed a variant of their construction with share size m+O(sec⁡⋅polylog(n,m,sec⁥))m + O(\sec\cdot\textrm{polylog}(n,m,\sec)) bits, but with super-polynomial reconstruction time. We present a robust secret sharing scheme that is secure against rushing adversaries, has shares of size m+O(sec⁥log⁥n(log⁥n+log⁥m))m+O(\sec \log{n} (\log{n}+\log{m})) bits, and has polynomial-time sharing and reconstruction. Central to our construction is a polynomial-time algorithm for a problem on semi-random graphs that arises naturally in the paradigm of local authentication of shares used by us and in the aforementioned work

    Standalone vertex ïŹnding in the ATLAS muon spectrometer

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    A dedicated reconstruction algorithm to find decay vertices in the ATLAS muon spectrometer is presented. The algorithm searches the region just upstream of or inside the muon spectrometer volume for multi-particle vertices that originate from the decay of particles with long decay paths. The performance of the algorithm is evaluated using both a sample of simulated Higgs boson events, in which the Higgs boson decays to long-lived neutral particles that in turn decay to bbar b final states, and pp collision data at √s = 7 TeV collected with the ATLAS detector at the LHC during 2011

    Measurements of Higgs boson production and couplings in diboson final states with the ATLAS detector at the LHC

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    Measurements are presented of production properties and couplings of the recently discovered Higgs boson using the decays into boson pairs, H →γ Îł, H → Z Z∗ →4l and H →W W∗ →lÎœlÎœ. The results are based on the complete pp collision data sample recorded by the ATLAS experiment at the CERN Large Hadron Collider at centre-of-mass energies of √s = 7 TeV and √s = 8 TeV, corresponding to an integrated luminosity of about 25 fb−1. Evidence for Higgs boson production through vector-boson fusion is reported. Results of combined ïŹts probing Higgs boson couplings to fermions and bosons, as well as anomalous contributions to loop-induced production and decay modes, are presented. All measurements are consistent with expectations for the Standard Model Higgs boson

    Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

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    The inclusive and dijet production cross-sections have been measured for jets containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The measurements use data corresponding to an integrated luminosity of 34 pb^-1. The b-jets are identified using either a lifetime-based method, where secondary decay vertices of b-hadrons in jets are reconstructed using information from the tracking detectors, or a muon-based method where the presence of a muon is used to identify semileptonic decays of b-hadrons inside jets. The inclusive b-jet cross-section is measured as a function of transverse momentum in the range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet cross-section is measured as a function of the dijet invariant mass in the range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets and the angular variable chi in two dijet mass regions. The results are compared with next-to-leading-order QCD predictions. Good agreement is observed between the measured cross-sections and the predictions obtained using POWHEG + Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet cross-section. However, it does not reproduce the measured inclusive cross-section well, particularly for central b-jets with large transverse momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final version published in European Physical Journal

    Measurement of the top quark-pair production cross section with ATLAS in pp collisions at \sqrt{s}=7\TeV

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    A measurement of the production cross-section for top quark pairs(\ttbar) in pppp collisions at \sqrt{s}=7 \TeV is presented using data recorded with the ATLAS detector at the Large Hadron Collider. Events are selected in two different topologies: single lepton (electron ee or muon Ό\mu) with large missing transverse energy and at least four jets, and dilepton (eeee, ΌΌ\mu\mu or eΌe\mu) with large missing transverse energy and at least two jets. In a data sample of 2.9 pb-1, 37 candidate events are observed in the single-lepton topology and 9 events in the dilepton topology. The corresponding expected backgrounds from non-\ttbar Standard Model processes are estimated using data-driven methods and determined to be 12.2±3.912.2 \pm 3.9 events and 2.5±0.62.5 \pm 0.6 events, respectively. The kinematic properties of the selected events are consistent with SM \ttbar production. The inclusive top quark pair production cross-section is measured to be \sigmattbar=145 \pm 31 ^{+42}_{-27} pb where the first uncertainty is statistical and the second systematic. The measurement agrees with perturbative QCD calculations.Comment: 30 pages plus author list (50 pages total), 9 figures, 11 tables, CERN-PH number and final journal adde

    Measurement of the top quark pair cross section with ATLAS in pp collisions at √s=7 TeV using final states with an electron or a muon and a hadronically decaying τ lepton

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    A measurement of the cross section of top quark pair production in proton-proton collisions recorded with the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 7 TeV is reported. The data sample used corresponds to an integrated luminosity of 2.05 fb -1. Events with an isolated electron or muon and a τ lepton decaying hadronically are used. In addition, a large missing transverse momentum and two or more energetic jets are required. At least one of the jets must be identified as originating from a b quark. The measured cross section, σtt-=186±13(stat.)±20(syst.)±7(lumi.) pb, is in good agreement with the Standard Model prediction

    Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment

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    This paper describes an analysis of the angular distribution of W->enu and W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with the ATLAS detector at the LHC in 2010, corresponding to an integrated luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and the missing transverse energy, the W decay angular distribution projected onto the transverse plane is obtained and analysed in terms of helicity fractions f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw > 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour, are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017 +/- 0.030, where the first uncertainties are statistical, and the second include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables, revised author list, matches European Journal of Physics C versio
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