LAS REFORMAS BASADAS EN ESTÁNDARES: UN CAMINO EQUIVOCADO

There have been important changes in the way of thinking and Management of education. Maybe the  change that has had the greatest impact in educational policy, has been the turn towards the change towards the measurement of achievement and it’s relation to standards. The purpose of this article is to show that if  what is wanted is to improve education, the adoption of a Standards Based approach is a wrong track. The article is organized into two parts. The first part presents 12 critical observations on Standard Based Reforms. The second part is a review of educational research on the subject.En las últimas décadas han ocurrido importantes cambios en la manera de pensar, gestionar la educación. Quizá el cambio que ha causado más impacto, en la política educativa, ha sido el giro hacia la medición del rendimiento académico y su vinculación a estándares. El propósito de este artículo es el de mostrar que si se quiere mejorar la educación, el  adoptar una política educativa de Reformas Basadas en Estándares es optar por un camino equivocado.  El artículo esta organizado en dos partes. En la primera se presentan 12 observaciones criticas relativas a las Reformas Basadas en Estándares y la segunda parte consiste en una revisión de investigaciones en las cuales se analiza el impacto de esta política. &nbsp

El precio de la evaluación estandarizada: la pérdida de calidad y la segmentación social

La calidad de la educación y sus concepciones y prácticas de evaluación son las preocupaciones centrales del autor del presente artículo. Su objetivo es mostra como las pruebas estandarizadas referidas a norma, como las de los sistemas de evaluación centralizadas, no sirven para los propósitos que se le atribuyen socialamente, ya que no informan acerca de la calidad de la educación. El llama atención al poder desmesurado dado a los instrumentos estandarizados de medición en la evaluación y la gestión del sistema educativo, argumentando que, al contrário de lo esperado, ellos fomentan la desigualdad y disminuyen la calidad de la educación

High-contrast imaging constraints on gas giant planet formation - The Herbig Ae/Be star opportunity

Planet formation studies are often focused on solar-type stars, implicitly considering our Sun as reference point. This approach overlooks, however, that Herbig Ae/Be stars are in some sense much better targets to study planet formation processes empirically, with their disks generally being larger, brighter and simply easier to observe across a large wavelength range. In addition, massive gas giant planets have been found on wide orbits around early type stars, triggering the question if these objects did indeed form there and, if so, by what process. In the following I briefly review what we currently know about the occurrence rate of planets around intermediate mass stars, before discussing recent results from Herbig Ae/Be stars in the context of planet formation. The main emphasis is put on spatially resolved polarized light images of potentially planet forming disks and how these images - in combination with other data - can be used to empirically constrain (parts of) the planet formation process. Of particular interest are two objects, HD100546 and HD169142, where, in addition to intriguing morphological structures in the disks, direct observational evidence for (very) young planets has been reported. I conclude with an outlook, what further progress we can expect in the very near future with the next generation of high-contrast imagers at 8-m class telescopes and their synergies with ALMA.Comment: Accepted by Astrophysics and Space Science as invited short review in special issue about Herbig Ae/Be stars; 12 pages incl. 5 figures, 2 tables and reference

Near-infrared imaging and spectroscopy of the nuclear region of the disturbed Virgo cluster spiral NGC 4438

We present near-infrared VLT ISAAC imaging and spectroscopy of the peculiar Virgo galaxy NGC 4438, whose nucleus has been classified as a LINER. The data are supplemented by mid-infrared imaging, and compared to previous WFPC2 HST broadband images. Images and position-velocity maps of the [Fe II] and H2 line emissions are presented and compared with the distribution of the optical narrow-line region and radio features. Our results show that shocks (possibly driven by a radio jet) contribute to an important fraction of the excitation of [Fe II], while X-ray heating from a central AGN may be responsible for the H2 excitation. We address the question whether the outflow has an AGN or a starburst origin by providing new estimates of the central star formation rate and the kinetic energy associated with the gas. By fitting a Sersic bulge, an exponential disc and a compact nuclear source to the light distribution, we decomposed NGC 4438's light distribution and found an unresolved nuclear source at 0.8 arcsec resolution with M_K = -18.7 and J-H = 0.69. Our measured bulge velocity dispersion, 142 km/s, together with the standard M_bh-sigma relation, suggests a central black hole mass of log(M_bh/Msun) ~ 7.0. The stellar kinematics measured from the near-infrared CO lines shows a strong peak in the velocity dispersion of 178 km/s in the central 0.5 arcsec, which is possible kinematic evidence of a central black hole. We calculated a general expression for the integrated Sersic profile flux density in elliptical geometry, including the case of 'disky' isophotes.Comment: 13 pages, 12 figures. Affiliation added. Higher resolution image

Sequential planet formation in the HD 100546 protoplanetary disk?

Context. The disk around the Herbig Ae star, HD 100546, shows structures that suggest the presence of two companions in the disk at ~10 and ~70 AU. The outer companion seems to be in the act of formation. Aims. Our aims are to provide constraints on the age of the planets in HD 100546 and to explore the potential evidence for sequential planet formation in transition disks such as HD 100546. Methods. We compare the recent resolved continuum observations of the disk around HD 100546 with the results of dust evolution simulations using an analytical prescription for the shapes of gaps carved by massive planets. Results. An inner pressure bump must have been present since early in the disk lifetime to have good agreement between the dust evolution models and the continuum observations of HD 100546. This pressure bump may have resulted from the presence of a very massive planet (~20 MJup), which formed early in the inner disk (r ~ 10 AU). If only this single planet exists, the disk is likely to be old, comparable to the stellar age (~5−10 Myr). Another possible explanation is an additional massive planet in the outer disk (r ~ 70 AU): either a low-mass outer planet (≲ 5 MJup) injected at early times, or a higher mass outer planet (≳15 MJup) formed very recently, traps the right amount of dust in pressure bumps to reproduce the observations. In the latter case, the disk could be much younger (~3.0 Myr). Conclusions. In the case in which two massive companions are embedded in the disk around HD 100546, as suggested in the literature, the outer companion could be at least ≳2.5 Myr younger than the inner companion

Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma

[Excerpt] Multiple myeloma (MM) is the third most common hematological malignancy, after Non-Hodgkin Lymphoma and Leukemia. MM is generally preceded by Monoclonal Gammopathy of Undetermined Significance (MGUS) [1], and epidemiological studies have identified older age, male gender, family history, and MGUS as risk factors for developing MM [2]. The somatic mutational landscape of sporadic MM has been increasingly investigated, aiming to identify recurrent genetic events involved in myelomagenesis. Whole exome and whole genome sequencing studies have shown that MM is a genetically heterogeneous disease that evolves through accumulation of both clonal and subclonal driver mutations [3] and identified recurrently somatically mutated genes, including KRAS, NRAS, FAM46C, TP53, DIS3, BRAF, TRAF3, CYLD, RB1 and PRDM1 [3,4,5]. Despite the fact that family-based studies have provided data consistent with an inherited genetic susceptibility to MM compatible with Mendelian transmission [6], the molecular basis of inherited MM predisposition is only partly understood. Genome-Wide Association (GWAS) studies have identified and validated 23 loci significantly associated with an increased risk of developing MM that explain ~16% of heritability [7] and only a subset of familial cases are thought to have a polygenic background [8]. Recent studies have identified rare germline variants predisposing to MM in KDM1A [9], ARID1A and USP45 [10], and the implementation of next-generation sequencing technology will allow the characterization of more such rare variants. [...]French National Cancer Institute (INCA) and the Fondation Française pour la Recherche contre le Myélome et les Gammapathies (FFMRG), the Intergroupe Francophone du Myélome (IFM), NCI R01 NCI CA167824 and a generous donation from Matthew Bell. This work was supported in part through the computational resources and staff expertise provided by Scientific Computing at the Icahn School of Medicine at Mount Sinai. Research reported in this paper was supported by the Office of Research Infrastructure of the National Institutes of Health under award number S10OD018522. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors thank the Association des Malades du Myélome Multiple (AF3M) for their continued support and participation. Where authors are identified as personnel of the International Agency for Research on Cancer / World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policy or views of the International Agency for Research on Cancer / World Health Organizatio

Why Are Outcomes Different for Registry Patients Enrolled Prospectively and Retrospectively? Insights from the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF).

Background: Retrospective and prospective observational studies are designed to reflect real-world evidence on clinical practice, but can yield conflicting results. The GARFIELD-AF Registry includes both methods of enrolment and allows analysis of differences in patient characteristics and outcomes that may result. Methods and Results: Patients with atrial fibrillation (AF) and ≥1 risk factor for stroke at diagnosis of AF were recruited either retrospectively (n = 5069) or prospectively (n = 5501) from 19 countries and then followed prospectively. The retrospectively enrolled cohort comprised patients with established AF (for a least 6, and up to 24 months before enrolment), who were identified retrospectively (and baseline and partial follow-up data were collected from the emedical records) and then followed prospectively between 0-18 months (such that the total time of follow-up was 24 months; data collection Dec-2009 and Oct-2010). In the prospectively enrolled cohort, patients with newly diagnosed AF (≤6 weeks after diagnosis) were recruited between Mar-2010 and Oct-2011 and were followed for 24 months after enrolment. Differences between the cohorts were observed in clinical characteristics, including type of AF, stroke prevention strategies, and event rates. More patients in the retrospectively identified cohort received vitamin K antagonists (62.1% vs. 53.2%) and fewer received non-vitamin K oral anticoagulants (1.8% vs . 4.2%). All-cause mortality rates per 100 person-years during the prospective follow-up (starting the first study visit up to 1 year) were significantly lower in the retrospective than prospectively identified cohort (3.04 [95% CI 2.51 to 3.67] vs . 4.05 [95% CI 3.53 to 4.63]; p = 0.016). Conclusions: Interpretations of data from registries that aim to evaluate the characteristics and outcomes of patients with AF must take account of differences in registry design and the impact of recall bias and survivorship bias that is incurred with retrospective enrolment. Clinical Trial Registration: - URL: http://www.clinicaltrials.gov . Unique identifier for GARFIELD-AF (NCT01090362)