Flora survey on Hiltaba Station and Gawler Ranges National Park: vascular plants, macrofungi, lichens, and bryophytes

In September 2012, five staff members of the State Herbarium of South Australia, Department of Environment, Water and Natural Resources (DEWNR), participated in a two week survey on Hiltaba Station and Gawler Ranges National Park. These staff collected vascular plants and cryptogams as part of the Bush Blitz Survey program. The primary survey effort was focussed on Hiltaba Station where records were made at 134 sites. Across the two properties the survey resulted in the collection of 782 plant specimens, plus a further 524 plant sighting records. The collections were supplemented by 136 vascular plant tissue samples collected in silica gel desiccant for future DNA analysis. A total of 88 plant taxa* were newly recorded for the Hiltaba Nature Foundation property during the 2012 Bush Blitz Survey. This comprised 36 vascular plant taxa and 52 cryptogams (26 bryophytes, 22 lichens, and 4 macrofungi). In the Gawler Ranges National Park, 21 plant taxa were recorded for the first time, comprising 12 vascular plant taxa and 9 cryptogams. The surveys have made a significant contribution to our knowledge of the flora on both properties.P.J. Lang, J. Kellermann, G.H. Bell, H.B. Cros

The Millennium Galaxy Catalogue: the space density and surface brightness distribution(s) of galaxies

We recover the joint and individual space density and surface brightness distribution(s) of galaxies from the Millennium Galaxy Catalogue. The MGC is a local survey spanning 30.9 sq deg and probing approximately one--two mag/sq arcsec deeper than either the Two-Degree Field Galaxy Redshift Survey (2dFGRS) or the Sloan Digital Sky Survey (SDSS). The MGC contains 10,095 galaxies to B_mgc < 20 mag with 96 per cent spectroscopic completeness. We implement a joint luminosity-surface brightness step-wise maximum likelihood method to recover the bivariate brightness distribution (BBD) inclusive of most selection effects. Integrating the BBD over surface brightness we recover the following Schechter function parameters: phi* = (0.0177 +/- 0.0015) h^3 Mpc^{-3}, M_{B}* - 5 log h = (-19.60 +/- 0.04) mag and alpha =-1.13 +/- 0.02. Compared to the 2dFGRS (Norberg et al 2002) we find a consistent M* value but a slightly flatter faint-end slope and a higher normalisation, resulting in a final luminosity density j_{b_J} = (1.99 +/- 0.17) x 10^8 h L_{odot} Mpc^{-3}. The MGC surface brightness distribution is a well bounded Gaussian at the M* point with phi* = (3.5 +/- 0.1) x 10^{-2} h^3 Mpc^{-3}, mu^{e*} = (21.90 +/- 0.01) mag/sq arcsec and sigma_{ln R_e} = 0.35 +/- 0.01. The characteristic surface brightness for luminous systems is invariant to M_{B} - 5 log h ~ -19 mag faintwards of which it moves to lower surface brightness. Higher resolution (FWHM 26 mag/sq arcsec in the B-band) observations of the local universe are now essential to probe to lower luminosity and lower surface brightness levels. [abridged]Comment: Accepted for publication in MNRAS, 26 pages with 21 figures (some degraded). A full pdf version, along with MGC data release, is available from the MGC website at, http://www.eso.org/~jliske/mg

An examination of biochemical parameters and their association with response to ketogenic dietary therapies

Objective: In the absence of specific metabolic disorders, accurate predictors of response to ketogenic dietary therapies (KDTs) for treating epilepsy are largely unknown. We hypothesized that specific biochemical parameters would be associated with the effectiveness of KDT in humans with epilepsy. The parameters tested were β-hydroxybutyrate, acetoacetate, nonesterified fatty acids, free and acylcarnitine profile, glucose, and glucose-ketone index (GKI). Methods: Biochemical results from routine blood tests conducted at baseline prior to initiation of KDT and at 3-month follow-up were obtained from 13 adults and 215 children with KDT response data from participating centers. One hundred thirty-two (57%) of 228 participants had some data at both baseline and 3 months; 52 (23%) of 228 had data only at baseline; 22 (10%) of 228 had data only at 3 months; and 22 (10%) of 228 had no data. KDT response was defined as ≥50% seizure reduction at 3-month follow-up. Results: Acetyl carnitine at baseline was significantly higher in responders (p < 0.007). It was not associated with response at 3-month follow-up. There was a trend for higher levels of free carnitine and other acylcarnitine esters at baseline and at 3-month follow-up in KDT responders. There was also a trend for greater differences in levels of propionyl carnitine and in β-hydroxybutyrate measured at baseline and 3-month follow-up in KDT responders. No other biochemical parameters were associated with response at any time point. Significance: Our finding that certain carnitine fractions, in particular baseline acetyl carnitine, are positively associated with greater efficacy of KDT is consistent with the theory that alterations in energy metabolism may play a role in the mechanisms of action of KDT. Go here for SF

Are galaxies with AGN a transition population?

We present the results of an analysis of a well-selected sample of galaxies with active and inactive galactic nuclei from the Sloan Digital Sky Survey, in the range 0.01 < z < 0.16. The SDSS galaxy catalogue was split into two classes of active galaxies, Type~2 AGN and composites, and one set of inactive, star-forming/passive galaxies. For each active galaxy, two inactive control galaxies were selected by matching redshift, absolute magnitude, inclination, and radius. The sample of inactive galaxies naturally divides into a red and a blue sequence, while the vast majority of AGN hosts occur along the red sequence. In terms of H-alpha equivalent width, the population of composite galaxies peaks in the valley between the two modes, suggesting a transition population. However, this effect is not observed in other properties such as colour-magnitude space, or colour-concentration plane. Active galaxies are seen to be generally bulge-dominated systems, but with enhanced H-alpha emission compared to inactive red-sequence galaxies. AGN and composites also occur in less dense environments than inactive red-sequence galaxies, implying that the fuelling of AGN is more restricted in high-density environments. These results are therefore inconsistent with theories in which AGN host galaxies are a `transition' population. We also introduce a systematic 3D spectroscopic imaging survey, to quantify and compare the gaseous and stellar kinematics of a well-selected, distance-limited sample of up to 20 nearby Seyfert galaxies, and 20 inactive control galaxies with well-matched optical properties. The survey aims to search for dynamical triggers of nuclear activity and address outstanding controversies in optical/IR imaging surveys.Comment: 12 pages, 8 figures, accepted by MNRA

Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility

Multiple sclerosis (MS) is an inflammatory disease of the CNS that is characterized by BBB dysfunction and has a much higher incidence in females. Compared with other strains of mice, EAE in the SJL mouse strain models multiple features of MS, including an enhanced sensitivity of female mice to disease; however, the molecular mechanisms that underlie the sex- and strain-dependent differences in disease susceptibility have not been described. We identified sphingosine-1-phosphate receptor 2 (S1PR2) as a sex- and strain-specific, disease-modifying molecule that regulates BBB permeability by destabilizing adherens junctions. S1PR2 expression was increased in disease-susceptible regions of the CNS of both female SJL EAE mice and female patients with MS compared with their male counterparts. Pharmacological blockade or lack of S1PR2 signaling decreased EAE disease severity as the result of enhanced endothelial barrier function. Enhanced S1PR2 signaling in an in vitro BBB model altered adherens junction formation via activation of Rho/ROCK, CDC42, and caveolin endocytosis-dependent pathways, resulting in loss of apicobasal polarity and relocation of abluminal CXCL12 to vessel lumina. Furthermore, S1PR2-dependent BBB disruption and CXCL12 relocation were observed in vivo. These results identify a link between S1PR2 signaling and BBB polarity and implicate S1PR2 in sex-specific patterns of disease during CNS autoimmunity

The zCOSMOS Redshift Survey: the role of environment and stellar mass in shaping the rise of the morphology-density relation from z~1

For more than two decades we have known that galaxy morphological segregation is present in the Local Universe. It is important to see how this relation evolves with cosmic time. To investigate how galaxy assembly took place with cosmic time, we explore the evolution of the morphology-density relation up to redshift z~1 using about 10000 galaxies drawn from the zCOSMOS Galaxy Redshift Survey. Taking advantage of accurate HST/ACS morphologies from the COSMOS survey, of the well-characterised zCOSMOS 3D environment, and of a large sample of galaxies with spectroscopic redshift, we want to study here the evolution of the morphology-density relation up to z~1 and its dependence on galaxy luminosity and stellar mass. The multi-wavelength coverage of the field also allows a first study of the galaxy morphological segregation dependence on colour. We further attempt to disentangle between processes that occurred early in the history of the Universe or late in the life of galaxies. The zCOSMOS field benefits of high-resolution imaging in the F814W filter from the Advanced Camera for Survey (ACS). We use standard morphology classifiers, optimised for being robust against band-shifting and surface brightness dimming, and a new, objective, and automated method to convert morphological parameters into early, spiral, and irregular types. We use about 10000 galaxies down to I_AB=22.5 with a spectroscopic sampling rate of 33% to characterise the environment of galaxies up to z~1 from the 100 kpc scales of galaxy groups up to the 100 Mpc scales of the cosmic web. ABRIDGEDComment: 23 pages, 12 figures, accepted for publication in Astronomy and Astrophysic

Galaxy Stellar Mass Assembly between 0.2<z<2 from the S-COSMOS survey

We follow the galaxy stellar mass assembly by morphological and spectral type in the COSMOS 2-deg^2 field. We derive the stellar mass functions and stellar mass densities from z=2 to z=0.2 using 196,000 galaxies selected at F(3.6 micron) > 1 microJy with accurate photometric redshifts (sigma_((zp-zs)/(1+zs))=0.008 at i<22.5). Using a spectral classification, we find that z~1 is an epoch of transition in the stellar mass assembly of quiescent galaxies. Their stellar mass density increases by 1.1 dex between z=1.5-2 and z=0.8-1 (Delta t ~2.5 Gyr), but only by 0.3 dex between z=0.8-1 and z~0.1 (Delta t ~ 6 Gyr). Then, we add the morphological information and find that 80-90% of the massive quiescent galaxies (log(M)~11) have an elliptical morphology at z<0.8. Therefore, a dominant mechanism links the shutdown of star formation and the acquisition of an elliptical morphology in massive galaxies. Still, a significant fraction of quiescent galaxies present a Spi/Irr morphology at low mass (40-60% at log(M)~9.5), but this fraction is smaller than predicted by semi-analytical models using a ``halo quenching'' recipe. We also analyze the evolution of star-forming galaxies and split them into ``intermediate activity'' and ``high activity'' galaxies. We find that the most massive ``high activity'' galaxies end their high star formation rate phase first. Finally, the space density of massive star-forming galaxies becomes lower than the space density of massive elliptical galaxies at z<1. As a consequence, the rate of ``wet mergers'' involved in the formation of the most massive ellipticals must decline very rapidly at z<1, which could explain the observed slow down in the assembly of these quiescent and massive sources.Comment: 37 pages, 29 figures, accepted for publication in Ap

Single-molecule experiments in biological physics: methods and applications

I review single-molecule experiments (SME) in biological physics. Recent technological developments have provided the tools to design and build scientific instruments of high enough sensitivity and precision to manipulate and visualize individual molecules and measure microscopic forces. Using SME it is possible to: manipulate molecules one at a time and measure distributions describing molecular properties; characterize the kinetics of biomolecular reactions and; detect molecular intermediates. SME provide the additional information about thermodynamics and kinetics of biomolecular processes. This complements information obtained in traditional bulk assays. In SME it is also possible to measure small energies and detect large Brownian deviations in biomolecular reactions, thereby offering new methods and systems to scrutinize the basic foundations of statistical mechanics. This review is written at a very introductory level emphasizing the importance of SME to scientists interested in knowing the common playground of ideas and the interdisciplinary topics accessible by these techniques. The review discusses SME from an experimental perspective, first exposing the most common experimental methodologies and later presenting various molecular systems where such techniques have been applied. I briefly discuss experimental techniques such as atomic-force microscopy (AFM), laser optical tweezers (LOT), magnetic tweezers (MT), biomembrane force probe (BFP) and single-molecule fluorescence (SMF). I then present several applications of SME to the study of nucleic acids (DNA, RNA and DNA condensation), proteins (protein-protein interactions, protein folding and molecular motors). Finally, I discuss applications of SME to the study of the nonequilibrium thermodynamics of small systems and the experimental verification of fluctuation theorems. I conclude with a discussion of open questions and future perspectives.Comment: Latex, 60 pages, 12 figures, Topical Review for J. Phys. C (Cond. Matt

Understanding the factors that determine workplace coaching effectiveness: a systematic literature review

Meta-analytic results have established that workplace coaching is effective, however, little is known about the determinants of coaching effectiveness. This paper reports an inclusive systematic literature review, covering the quantitative and qualitative research on workplace coaching. We focus on seven promising areas in the current workplace coaching literature that emerged by the synthesis of 117 empirical studies: self-efficacy, coaching motivation, goal orientation, trust, interpersonal attraction, feedback intervention, and supervisory support. The major contribution of our paper is the systematic integration of well-established theoretical constructs in the workplace coaching context and the new insights we provide in the synthesis of these literatures. Based on our review we provide specific recommendations to be addressed in future research, including recommended research methodologies, which we propose will significantly progress the field of workplace coaching theory and practice

The state of the Martian climate

60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes