Anxiety and cognitive bias in children and young people who stutter

Psychologists recognise various forms of anxiety, such as generalized anxiety disorder, separation anxiety and social phobia. People who stutter are at risk of elevated levels of anxiety, especially social phobia. Recent research has suggested that anxiety may be caused and maintained by cognitive biases such as preferentially allocating attention towards threat stimuli. These biases can be re-trained using cognitive bias modification with resulting improvements in levels of anxiety. In the present study, we measured different forms of anxiety and attentional bias for faces among 8-18 year olds attending the Michael Palin Centre for treatment for stuttering. The clients and their parent(s) completed the child and parent versions, respectively, of the Screen for Childhood Anxiety Related Emotional Disorders (SCARED), which provides an overall anxiety score and sub-scores, with clinical cut-offs, for generalized anxiety disorder, separation anxiety, social phobia, school avoidance and panic. The clients also performed a computerised measure of attentional bias for faces, using schematic stimuli. Levels of anxiety were higher than in the general population, and prevalence increased with age. There was a significant correlation between SCARED scores produced by clients and their parents. Socially anxious participants showed a bias towards sad faces

Gauge Boson - Gauge Boson Scattering in Theories with Large Extra Dimensions

We consider the scattering amplitudes of the form V_1 V_2 -> V_3 V_4, where V_i=\gamma, Z, W or g(=gluon) are the Standard Model gauge bosons, due to graviton exchange in Kaluza-Klein theories with large extra dimensions. This leads to a number of experimentally viable signatures at high energy leptonic and hadronic colliders. We discuss the observability or future limits on the scale of the gravitational interactions (m_D), that may be obtained at an e+e- Next Linear Collider (NLC) and at the LHC, by studying some of these type of gauge boson scattering processes. We find that the attainable limits through these type of processes are: m_D > 3 TeV at the NLC and m_D > 6 TeV at the LHC.Comment: 27 pages, plain latex, 7 figures embadded in the text using epsfi

Graviton Production By Two Photon and Electron-Photon Processes In Kaluza-Klein Theories With Large Extra Dimensions

We consider the production of gravitons via two photon and electron-photon fusion in Kaluza-Klein theories which allow TeV scale gravitational interactions. We show that at electron-positron colliders, the processes l+l- -> l+ l- graviton, with l=e, mu, can lead to a new signal of low energy gravity of the form l+l- -> l+l- + missing energy which is well above the Standard Model background. For example, with two extra dimensions at the Next Linear Collider with a center of mass energy of 500 or 1000 GeV, hundreds to thousands such l+ l- graviton events may be produced if the scale of the gravitational interactions, M_D, is around a few TeV. At a gamma-electron collider, more stringent bounds may be placed on M_D via the related reaction e^-\gamma -> e^- graviton. For instance, if a 1TeV electron positron collider is converted to an electron-photon collider, a bound of ~10TeV may be placed on the scale M_D if the number of extra dimensions delta=2 while a bound of ~4TeV may be placed if delta=4.Comment: 25 pages 6 figures, minor changes made in the text and changes in reference

Moderate threat causes longer lasting disruption to processing in anxious individuals

Anxiety is associated with increased attentional capture by threat. Previous studies have used simultaneous or briefly separated (<1 s) presentation of threat distractors and target stimuli. Here, we tested the hypothesis that high trait anxious participants would show a longer time window within which distractors cause disruption to subsequent task processing, and that this would particularly be observed for stimuli of moderate or ambiguous threat value. A novel temporally separated emotional distractor task was used. Face or house distractors were presented for 250 ms at short (∼1.6 s) or long (∼3 s) intervals prior to a letter string comprising Xs or Ns. Trait anxiety was associated with slowed identification of letter strings presented at long intervals after face distractors with part surprise/part fear expressions. In other words, these distractors had an impact on high anxious individuals' speed of target identification seconds after their offset. This was associated with increased activity in the fusiform gyrus and amygdala and reduced dorsal anterior cingulate recruitment. This pattern of activity may reflect impoverished recruitment of reactive control mechanisms to damp down stimulus-specific processing in subcortical and higher visual regions. These findings have implications for understanding how threat-related attentional biases in anxiety may lead to dysfunction in everyday settings where stimuli of moderate, potentially ambiguous, threat value such as those used here are fairly common, and where attentional disruption lasting several seconds may have a profound impact

Effect of trait anxiety on prefrontal control mechanisms during emotional conflict

International audienceConverging evidence points to a link between anxiety proneness and altered emotional functioning, including threat-related biases in selective attention and higher susceptibility to emotionally ambiguous stimuli. However, during these complex emotional situations, it remains unclear how trait anxiety affects the engagement of the prefrontal emotional control system and particularly the anterior cingulate cortex (ACC), a core region at the intersection of the limbic and prefrontal systems. Using an emotional conflict task and functional magnetic resonance imaging (fMRI), we investigated in healthy subjects the relations between trait anxiety and both regional activity and functional connectivity (psychophysiological interaction) of the ACC. Higher levels of anxiety were associated with stronger task-related activation in ACC but with reduced functional connectivity between ACC and lateral prefrontal cortex (LPFC). These results support the hypothesis that when one is faced with emotionally incompatible information, anxiety leads to inefficient high-order control, characterized by insufficient ACC-LPFC functional coupling and increases, possibly compensatory, in activation of ACC. Our findings provide a deeper understanding of the pathophysiology of the neural circuitry underlying anxiety and may offer potential treatment markers for anxiety disorders

Dijet Production at Hadron Colliders in Theories with Large Extra Dimensions

We consider the production of high invariant mass jet pairs at hadron colliders as a test for TeV scale gravitational effects. We find that this signal can probe effective Planck masses of about 10 TeV at the LHC with center of mass energy of 14 TeV and 1.5 TeV at the Tevatron with center of mass energy of 2 TeV. These results are compared to analogous scattering processes at leptonic colliders.Comment: 15 pages with 3 figure

Attentional and interpretative biases in appearance concern: An investigation of biases in appearance-related information processing

The present study examined associations between high levels of appearance concern and information processing biases in interpretation and attention. An opportunity sample (N = 79) categorised ambiguous stimuli as related or unrelated to appearance. Participants then responded to the same stimuli in a modified visual dot-probe task assessing attentional bias. Participant responses were assessed in relation to level of appearance concern. The results indicated a valence specific bias towards interpretation of ambiguous stimuli as negative and appearance-related in individuals with higher levels of concern. There was also evidence of attentional bias towards information perceived as appearance-related in participants with higher levels of appearance concern. The study findings suggest that association between appearance-orientated information processing biases and level of appearance concern; this association may lead to mutually reinforcing bias and concern. © 2010 Elsevier Ltd. All rights reserved

Predictive uncertainty in auditory sequence processing

Copyright © 2014 Hansen and Pearce. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms

Probing the unparticle signal in b→db \to d penguin processes

We investigate the effect of unparticles in the pure $b \to d$ penguin processes $B^0 \to K^0 \bar K^0$ and $B^{+,0} \to \phi \pi^{+,0}$. Since these processes receive dominant contributions due to the {\it top} quark in the loop, direct and mixing-induced CP asymmetry parameters in these processes are expected to be vanishingly small in the standard model. We find that due to the unparticle effect sizable nonzero CP violation could be possible in these channels.Comment: 12 pages, 4 figures, version to appear in Phys. Lett.

Interpretation of ambiguous situations: evidence for a dissociation between social and physical threat in Williams syndrome

There is increasing evidence that Williams syndrome (WS) is associated with elevated anxiety that is non-social in nature, including generalised anxiety and fears. To date very little research has examined the cognitive processes associated with this anxiety. In the present research, attentional bias for non-social threatening images in WS was examined using a dot-probe paradigm. Participants were 16 individuals with WS aged between 13 and 34 years and two groups of typically developing controls matched to the WS group on chronological age and attentional control ability respectively. The WS group exhibited a significant attention bias towards threatening images. In contrast, no bias was found for group matched on attentional control and a slight bias away from threat was found in the chronological age matched group. The results are contrasted with recent findings suggesting that individuals with WS do not show an attention bias for threatening faces and discussed in relation to neuroimaging research showing elevated amygdala activation in response to threatening non-social scenes in WS