56 research outputs found
Supersymmetric Leptogenesis
We study leptogenesis in the supersymmetric standard model plus the seesaw.
We identify important qualitative differences that characterize supersymmetric
leptogenesis with respect to the non-supersymmetric case. The lepton number
asymmetries in fermions and scalars do not equilibrate, and are related via a
non-vanishing gaugino chemical potential. Due to the presence of new anomalous
symmetries, electroweak sphalerons couple to winos and higgsinos, and QCD
sphalerons couple to gluinos, thus modifying the corresponding chemical
equilibrium conditions. A new constraint on particles chemical potentials
corresponding to an exactly conserved -charge, that also involves the number
density asymmetry of the heavy sneutrinos, appears. These new ingredients
determine the matrices that mix up the density asymmetries of the
lepton flavours and of the heavy sneutrinos. We explain why in all temperature
ranges the particle thermodynamic system is characterized by the same number of
independent quantities. Numerical differences with respect to usual treatment
remain at the level.Comment: 30 pages, 2 figures. Typos corrected, one reference added. Version
published in JCA
Doubly Coexisting Dark Matter Candidates in an Extended Seesaw Model
We examine how a scenario of coexisting two-particle dark mater can be
realized in the extended seesaw model, which we have proposed previously to
accommodate small neutrino masses and low scale leptogenesis with an
introduction of singlet Majorana neutrino and singlet scalar . We now
impose the discrete symmetry and introduce new
renormalizable interaction terms with a new heavy singlet scalar particle
so as for previously introduced and to be doubly coexisting
dark matter candidates. Depending on the mass spectrum of the two dark matter
candidates, the annihilation process either or
is of particular interest because the annihilation
cross sections for the processes can be so large that the relic abundance of
decaying particle should get lowered, which in turn makes the constraints on
its parameter space relaxed, compared with the case of one and only one dark
matter candidate. We discuss the implications of the dark matter detection
through the scattering off the nucleus of the detecting material on our
scenarios for dark matter candidates. We also study the implications for the
search of invisible Higgs decay at LHC, which may serve as a probe of our
scenario for dark matter.Comment: modified to renormalizable model
Observational Constraints on Chaplygin Quartessence: Background Results
We derive the constraints set by several experiments on the quartessence
Chaplygin model (QCM). In this scenario, a single fluid component drives the
Universe from a nonrelativistic matter-dominated phase to an accelerated
expansion phase behaving, first, like dark matter and in a more recent epoch
like dark energy. We consider current data from SNIa experiments, statistics of
gravitational lensing, FR IIb radio galaxies, and x-ray gas mass fraction in
galaxy clusters. We investigate the constraints from this data set on flat
Chaplygin quartessence cosmologies. The observables considered here are
dependent essentially on the background geometry, and not on the specific form
of the QCM fluctuations. We obtain the confidence region on the two parameters
of the model from a combined analysis of all the above tests. We find that the
best-fit occurs close to the CDM limit (). The standard
Chaplygin quartessence () is also allowed by the data, but only at
the level.Comment: Replaced to match the published version, references update
Linear and non-linear perturbations in dark energy models
I review the linear and second-order perturbation theory in dark energy
models with explicit interaction to matter in view of applications to N-body
simulations and non-linear phenomena. Several new or generalized results are
obtained: the general equations for the linear perturbation growth; an
analytical expression for the bias induced by a species-dependent interaction;
the Yukawa correction to the gravitational potential due to dark energy
interaction; the second-order perturbation equations in coupled dark energy and
their Newtonian limit. I also show that a density-dependent effective dark
energy mass arises if the dark energy coupling is varying.Comment: 12 pages, submitted to Phys. Rev; v2: added a ref. and corrected a
typ
Cosmological consequences of a Chaplygin gas dark energy
A combination of recent observational results has given rise to what is
currently known as the dark energy problem. Although several possible
candidates have been extensively discussed in the literature to date the nature
of this dark energy component is not well understood at present. In this paper
we investigate some cosmological implications of another dark energy candidate:
an exotic fluid known as the Chaplygin gas, which is characterized by an
equation of state , where is a positive constant. By assuming
a flat scenario driven by non-relativistic matter plus a Chaplygin gas dark
energy we study the influence of such a component on the statistical properties
of gravitational lenses. A comparison between the predicted age of the universe
and the latest age estimates of globular clusters is also included and the
results briefly discussed. In general, we find that the behavior of this class
of models may be interpreted as an intermediary case between the standard and
CDM scenarios.Comment: 7 pages, 5 figures, to appear in Phys. Rev.
Design, Synthesis and Characterization of N-oxide-containing Heterocycles with In vivo Sterilizing Antitubercular Activity
Tuberculosis, caused by the Mycobacterium tuberculosis (Mtb), is the infectious disease
responsible for the highest number of deaths worldwide. Herein, 22 new N-oxide-
containing compounds were synthesized followed by in vitro and in vivo evaluation of
their antitubercular potential against Mtb. Compound 8 was found to be the most
promising compound, with MIC90 values of 1.10 and 6.62 μM against active and non-
replicating Mtb, respectively. Additionally, we carried out in vivo experiments to confirm
the safety and efficacy of compound 8; the compound was found to be orally bioavailable
and highly effective leading to the reduction of the number of Mtb to undetected levels in
a mouse model of infection. Microarray-based initial studies on the mechanism of action
suggest that compound 8 blocks the process of translation. Altogether, these results
indicated benzofuroxan derivative 8 to be a promising lead compound for the
development of a novel chemical class of antitubercular drugs
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