Impacts of Climate Change on Volcanic Stratospheric Injections: Comparison of 1-D and 3-D Plume Model Projections

©2019. American Geophysical Union. All Rights Reserved. Explosive volcanic eruptions are one of the most important driver of climate variability. Yet, we still lack a fundamental understanding of how climate change may affect future eruptions. Here, we use an ensemble of simulations by 1-D and 3-D volcanic plume models spanning a large range of eruption source and atmospheric conditions to assess changes in the dynamics of future eruptive columns. Our results shed new light on differences between the predictions of 1-D and 3-D plume models. Furthermore, both models suggest that as a result of ongoing climate change, for tropical eruptions, (i) higher eruption intensities will be required for plumes to reach the upper troposphere/lower stratosphere and (ii) the height of plumes currently reaching the upper troposphere/lower stratosphere or above will increase. We discuss the implications of these results for the climatic impacts of future eruptions. Our simulations can directly inform climate model experiments on climate-volcano feedback.T.J.A.acknowledges funding from the Royal Society through a Newton International Fellowship (Grant NIF⧵R1⧵-180809).M. C. acknowledges CINECA Award N. HP10BRDK2T (2017) for high-performance computing resources used for testing the ASHEEcode; the FISR 2016 “Centro di studioe monitoraggio dei rischi naturalidellItalia centrale” project framework,managed by the Italian National Institute of Geophysics and Volcanology (INGV) and funded by the Italian Ministry of Education,University and Research; and the European Unions Horizon 2020 research and innovation program under Grant Agreement 731070. T. J.A. and A.M.J. acknowledge support from the Natural Sciences and Engineering Research Council of Canada during completion of this work

Impact of global warming on the rise of volcanic plumes and implications for future volcanic aerosol forcing

©2016. American Geophysical Union. All Rights Reserved. Volcanic eruptions have a significant impact on climate when they inject sulfur gases into the stratosphere. The dynamics of eruption plumes is also affected by climate itself, as atmospheric stratification impacts plumes' height. We use an integral plume model to assess changes in volcanic plume maximum rise heights as a consequence of global warming, with atmospheric conditions from an ensemble of global climate models, using three representative concentration pathways (RCP) scenarios. Predicted changes in atmospheric temperature profiles decrease the heights of tropospheric and lowermost stratospheric volcanic plumes and increase the tropopause height, for the RCP4.5 and RCP8.5 scenarios in the coming three centuries. Consequently, the critical mass eruption rate required to cross the tropopause increases by up to a factor of 3 for tropical regions and up to 2 for high-latitude regions. A number of recent lower stratospheric plumes, mostly in the tropics (e.g., Merapi, 2010), would be expected to not cross the tropopause starting from the late 21st century, under RCP4.5 and RCP8.5 scenarios. This effect could result in a ≃5–25% decrease in the average SO2 flux into the stratosphere carried by small plumes, the frequency of which is larger than the rate of decay of volcanic stratospheric aerosol, and a ≃2–12% decrease of the total flux. Our results suggest the existence of a positive feedback between climate and volcanic aerosol forcing. Such feedback may have minor implications for global warming rate but can prove to be important to understand the long-term evolution of volcanic atmospheric inputs

Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal

BACKGROUND: Characteristic symptoms of malaria include recurrent fever attacks and neurodegeneration, signs that are also found in patients with a hyperactive Nalp3 inflammasome. Plasmodium species produce a crystal called hemozoin that is generated by detoxification of heme after hemoglobin degradation in infected red blood cells. Thus, we hypothesized that hemozoin could activate the Nalp3 inflammasome, due to its particulate nature reminiscent of other inflammasome-activating agents. METHODOLOGY/PRINCIPAL FINDINGS: We found that hemozoin acts as a proinflammatory danger signal that activates the Nalp3 inflammasome, causing the release of IL-1beta. Similar to other Nalp3-activating particles, hemozoin activity is blocked by inhibiting phagocytosis, K(+) efflux and NADPH oxidase. In vivo, intraperitoneal injection of hemozoin results in acute peritonitis, which is impaired in Nalp3-, caspase-1- and IL-1R-deficient mice. Likewise, the pathogenesis of cerebral malaria is dampened in Nalp3-deficient mice infected with Plasmodium berghei sporozoites, while parasitemia remains unchanged. SIGNIFICANCE/CONCLUSIONS: The potent pro-inflammatory effect of hemozoin through inflammasome activation may possibly be implicated in plasmodium-associated pathologies such as cerebral malaria

Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal

BACKGROUND: Characteristic symptoms of malaria include recurrent fever attacks and neurodegeneration, signs that are also found in patients with a hyperactive Nalp3 inflammasome. Plasmodium species produce a crystal called hemozoin that is generated by detoxification of heme after hemoglobin degradation in infected red blood cells. Thus, we hypothesized that hemozoin could activate the Nalp3 inflammasome, due to its particulate nature reminiscent of other inflammasome-activating agents. METHODOLOGY/PRINCIPAL FINDINGS: We found that hemozoin acts as a proinflammatory danger signal that activates the Nalp3 inflammasome, causing the release of IL-1beta. Similar to other Nalp3-activating particles, hemozoin activity is blocked by inhibiting phagocytosis, K(+) efflux and NADPH oxidase. In vivo, intraperitoneal injection of hemozoin results in acute peritonitis, which is impaired in Nalp3-, caspase-1- and IL-1R-deficient mice. Likewise, the pathogenesis of cerebral malaria is dampened in Nalp3-deficient mice infected with Plasmodium berghei sporozoites, while parasitemia remains unchanged. SIGNIFICANCE/CONCLUSIONS: The potent pro-inflammatory effect of hemozoin through inflammasome activation may possibly be implicated in plasmodium-associated pathologies such as cerebral malaria

Taphonomic Criteria for Identifying Iberian Lynx Dens in Quaternary Deposits

For decades, taphonomists have dedicated their efforts to assessing the nature of the massive leporid accumulations recovered at archaeological sites in the northwestern Mediterranean region. Their interest lying in the fact that the European rabbit constituted a critical part of human subsistence during the late Pleistocene and early Holocene. However, rabbits are also a key prey in the food webs of Mediterranean ecosystems and the base of the diet for several specialist predators, including the Iberian lynx (Lynx pardinus). For this reason, the origin of rabbit accumulations in northwestern Mediterranean sites has proved a veritable conundrum. Here, we present the zooarchaeological and taphonomic study of more than 3000 faunal and 140 coprolite remains recovered in layer IIIa of Cova del Gegant (Catalonia, Spain). Our analysis indicates that this layer served primarily as a den for the Iberian lynx. The lynxes modified and accumulated rabbit remains and also died at the site creating an accumulation dominated by the two taxa. However, other agents and processes, including human, intervened in the final configuration of the assemblage. Our study contributes to characterizing the Iberian lynx fossil accumulation differentiating between the faunal assemblages accumulated by lynxes and hominins

Search for dark matter at √s=13 TeV in final states containing an energetic photon and large missing transverse momentum with the ATLAS detector

Results of a search for physics beyond the Standard Model in events containing an energetic photon and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. As the number of events observed in data, corresponding to an integrated luminosity of 36.1 fb−1 of proton–proton collisions at a centre-of-mass energy of 13 TeV, is in agreement with the Standard Model expectations, model-independent limits are set on the fiducial cross section for the production of events in this final state. Exclusion limits are also placed in models where dark-matter candidates are pair-produced. For dark-matter production via an axial-vector or a vector mediator in the s-channel, this search excludes mediator masses below 750–1200 GeV for dark-matter candidate masses below 230–480 GeV at 95% confidence level, depending on the couplings. In an effective theory of dark-matter production, the limits restrict the value of the suppression scale M∗ to be above 790 GeV at 95% confidence level. A limit is also reported on the production of a high-mass scalar resonance by processes beyond the Standard Model, in which the resonance decays to Zγ and the Z boson subsequently decays into neutrinos