Global Hopf bifurcation in the ZIP regulatory system

Regulation of zinc uptake in roots of Arabidopsis thaliana has recently been modeled by a system of ordinary differential equations based on the uptake of zinc, expression of a transporter protein and the interaction between an activator and inhibitor. For certain parameter choices the steady state of this model becomes unstable upon variation in the external zinc concentration. Numerical results show periodic orbits emerging between two critical values of the external zinc concentration. Here we show the existence of a global Hopf bifurcation with a continuous family of stable periodic orbits between two Hopf bifurcation points. The stability of the orbits in a neighborhood of the bifurcation points is analyzed by deriving the normal form, while the stability of the orbits in the global continuation is shown by calculation of the Floquet multipliers. From a biological point of view, stable periodic orbits lead to potentially toxic zinc peaks in plant cells. Buffering is believed to be an efficient way to deal with strong transient variations in zinc supply. We extend the model by a buffer reaction and analyze the stability of the steady state in dependence of the properties of this reaction. We find that a large enough equilibrium constant of the buffering reaction stabilizes the steady state and prevents the development of oscillations. Hence, our results suggest that buffering has a key role in the dynamics of zinc homeostasis in plant cells.Comment: 22 pages, 5 figures, uses svjour3.cl

Generalized N=1 Orientifold Compactifications and the Hitchin functionals

The four-dimensional N=1 supergravity theories arising in compactifications of type IIA and type IIB on generalized orientifold backgrounds with background fluxes are discussed. The Kahler potentials are derived for reductions on SU(3) structure orientifolds and shown to consist of the logarithm of the two Hitchin functionals. These are functions of even and odd forms parameterizing the geometry of the internal manifold, the B-field and the dilaton. The superpotentials induced by background fluxes and the non-Calabi-Yau geometry are determined by a reduction of the type IIA and type IIB fermionic actions on SU(3) and generalized SU(3) x SU(3) manifolds. Mirror spaces of Calabi-Yau orientifolds with electric and part of the magnetic NS-NS fluxes are conjectured to be certain SU(3) x SU(3) structure manifolds. Evidence for this identification is provided by comparing the generalized type IIA and type IIB superpotentials.Comment: 57 pages, references adde

Geometric Transitions on non-Kaehler Manifolds

This article is based on the author's PhD--thesis. We study geometric transitions on the supergravity level using the basic idea of arXiv:hep-th/0403288, where a pair of non-Kaehler backgrounds was constructed, which are related by a geometric transition. Here we embed this idea into an orientifold setup as suggested in arXiv:hep-th/0511099. The non-Kaehler backgrounds we obtain in type IIA are non-trivially fibered due to their construction from IIB via T-duality with Neveu-Schwarz flux. We demonstrate that these non-Kaehler manifolds are not half-flat and show that a symplectic structure exists on them at least locally. We also review the construction of new non-Kaehler backgrounds in type I and heterotic theory as proposed in arXiv:hep-th/0408192. They are found by a series of T- and S-duality and can be argued to be related by geometric transitions as well. A local toy model is provided that fulfills the flux equations of motion in IIB and the torsional relation in heterotic theory, and that is consistent with the U-duality relating both theories. For the heterotic theory we also propose a global solution that fulfills the torsional relation because it is similar to the Maldacena-Nunez background.Comment: 127 pages, based on PhD-thesis, v2 some references added, this version to appear in Fort. Phy

The Most Probable Size of the Universe

It has recently been suggested, by Firouzjahi, Sarangi, and Tye, that string-motivated modifications of the Hartle-Hawking wave function predict that our Universe came into existence from "nothing" with a de Sitter-like spacetime geometry and a spacetime curvature similar to that of "low-scale" models of Inflation. This means, however, that the Universe was quite large at birth. It would be preferable for the initial scale to be close to the string scale, or perhaps the Planck scale. The problem with this, however, is to explain how any initial homogeneity is preserved during the pre-inflationary era, so that Inflation can indeed begin. Here we modify a suggestion due to Linde and assume that the Universe was born with the topology of a torus; however, we propose that the size of the torus is to be predicted by the FST wave function. The latter does predict an initial size for the torus at about the string scale, and it also predicts a pre-inflationary spacetime geometry such that chaotic mixing preserves any initial homogeneity until Inflation can begin at a relatively low scale.Comment: References added; accepted by Nuclear Physics

Pre-Inflationary Spacetime in String Cosmology

Seiberg and Witten have shown that the non-perturbative stability of string physics on conformally compactified spacetimes is related to the behaviour of the areas and volumes of certain branes as the brane is moved towards infinity. If, as is particularly natural in quantum cosmology, the spatial sections of an accelerating cosmological model are flat and compact, then the spacetime is on the brink of disaster: it turns out that the version of inflationary spacetime geometry with toral spatial sections is marginally stable in the Seiberg-Witten sense. The question is whether the system remains stable before and after Inflation, when the spacetime geometry is distorted away from the inflationary form but still has flat spatial sections. We show that it is indeed possible to avoid disaster, but that requiring stability at all times imposes non-trivial conditions on the spacetime geometry of the early Universe in string cosmology. This in turn allows us to suggest a candidate for the structure which, in the earliest Universe, forbids cosmological singularities.Comment: Final version to appear in NPB, 27 pages including 1 eps figur

Accidental Inflation in String Theory

We show that inflation in type IIB string theory driven by the volume modulus can be realized in the context of the racetrack-based Kallosh-Linde model (KL) of moduli stabilization. Inflation here arises through the volume modulus slow-rolling down from a flat hill-top or inflection point of the scalar potential. This situation can be quite generic in the landscape, where by uplifting one of the two adjacent minima one can turn the barrier either to a flat saddle point or to an inflection point supporting eternal inflation. The resulting spectral index is tunable in the range of 0.93 < n_s < 1, and there is only negligible production of primordial gravitational waves r < 10^{-6}. The flatness of the potential in this scenario requires fine-tuning, which may be justified taking into account the exponential reward by volume factors preferring the regions of the universe with the maximal amount of slow-roll inflation. This consideration leads to a tentative prediction of the spectral index $n_s\approx 0.95$ or $n_s \approx 0.93$ depending on whether the potential has a symmetry phi -> - phi or not.Comment: 15 pages, 6 figures, LaTeX, uses RevTex

LSST: from Science Drivers to Reference Design and Anticipated Data Products

(Abridged) We describe here the most ambitious survey currently planned in the optical, the Large Synoptic Survey Telescope (LSST). A vast array of science will be enabled by a single wide-deep-fast sky survey, and LSST will have unique survey capability in the faint time domain. The LSST design is driven by four main science themes: probing dark energy and dark matter, taking an inventory of the Solar System, exploring the transient optical sky, and mapping the Milky Way. LSST will be a wide-field ground-based system sited at Cerro Pach\'{o}n in northern Chile. The telescope will have an 8.4 m (6.5 m effective) primary mirror, a 9.6 deg$^2$ field of view, and a 3.2 Gigapixel camera. The standard observing sequence will consist of pairs of 15-second exposures in a given field, with two such visits in each pointing in a given night. With these repeats, the LSST system is capable of imaging about 10,000 square degrees of sky in a single filter in three nights. The typical 5$\sigma$ point-source depth in a single visit in $r$ will be $\sim 24.5$ (AB). The project is in the construction phase and will begin regular survey operations by 2022. The survey area will be contained within 30,000 deg$^2$ with $\delta<+34.5^\circ$, and will be imaged multiple times in six bands, $ugrizy$, covering the wavelength range 320--1050 nm. About 90\% of the observing time will be devoted to a deep-wide-fast survey mode which will uniformly observe a 18,000 deg$^2$ region about 800 times (summed over all six bands) during the anticipated 10 years of operations, and yield a coadded map to $r\sim27.5$. The remaining 10\% of the observing time will be allocated to projects such as a Very Deep and Fast time domain survey. The goal is to make LSST data products, including a relational database of about 32 trillion observations of 40 billion objects, available to the public and scientists around the world.Comment: 57 pages, 32 color figures, version with high-resolution figures available from https://www.lsst.org/overvie