138 research outputs found

    Modeling a run-around heat and moisture exchanger using two counter/cross flow exchangers

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    In this study, a numerical model is developed for determining coupled heat and moisture transfer in a run-around membrane energy exchanger (RAMEE) using two counter/cross flow exchangers and with a salt solution of MgCl2 as the coupling fluid. The counter/cross flow exchanger is a counter-flow exchanger with cross-flow inlet and outlet headers. The model is two-dimensional, steady-state and based on the physical principles of conservation of momentum, energy, and mass. The finite difference method is used in this model to discretize the governing equations. The heat transfer model is validated with effectiveness correlations in the literature. It is shown that the difference between the numerical model and correlations is less than ¡À2% and ¡À2.5% for heat exchangers and run around heat exchangers (RAHE), respectively. The simultaneous heat and moisture transfer model is validated with data from another model and experiments. The inter-model comparison shows a difference of less than 1%. The experimental validation shows an average discrepancy of 1% to 17% between the experimental and numerical data for overall total effectiveness. At lower NTUs the numerical and experimental results show better agreement (e.g. within 1-4% at NTU=4). The model for RAHE is used to develop new effectiveness correlations for the geometrically more complex counter/cross flow heat exchangers and RAHE systems. The correlations are developed to predict the response of the exchangers and overall system to the change of different design characteristics as it is determined by the model. Discrepancies between the simulated and correlated results are within ¡À2% for both the heat exchangers and the RAHE systems. It is revealed by the model that the overall effectiveness of the counter/cross flow RAMEE depends on the entrance ratio (the ratio of the length of the inlet and outlet headers to the length of the exchanger, xi/x0), aspect ratio (the ratio of the height to the length of the exchanger, y0/x0), number of heat transfer units (NTU), heat capacity rate ratio (Cr*), number of mass transfer units (NTUm), and the mass flow rate ratio of pure salt in desiccant solution to dry air (m*). Beside these dimensionless parameters, the performance of the RAMEE system is affected by the liquid-air flow configuration and the operating inlet temperature and humidity. This study concludes that the maximum effectiveness of the RAMEE system with two counter/cross flow exchangers occurs when NTU and NTUm are large (e.g. greater than 10). At any NTU, the overall effectiveness of the RAMEE system increases with Cr* until it reaches a maximum value when Cr*= . Increasing Cr* above causes the overall effectiveness to decrease slightly. Therefore, to achieve the maximum overall effectiveness of the system, Cr* must be close to . is a function of NTU and operating conditions e.g., with NTU=10, and under AHRI summer and winter operating conditions, respectively. The exchangers in the RAMEE system are needed to have a small aspect ratio (e.g. y0/x

    Adsorptive removal of siloxanes from biogas : recent advances in catalyst reusability and water content effect

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    Altres ajuts: acords transformatius de la UABThe valorization of biogas as a renewable energy source faces a major obstacle regarding its purification. Siloxane is one of the impurities that cause problems such as damages to equipment of combustion engines, turbines, and boilers used for biogas conversion to heat and electricity. In this review, adsorption for siloxane removal is widely discussed, with two specific approaches: adsorbents sensitivity to water and regeneration, two essential points for industrial application. Thus, determining factors in adsorbents capacity, reusability, and water tolerance including textural properties, surface functional groups, and hydrophobicity are deeply analyzed. Studies oriented to the optimization of traditional adsorbents such as activated carbon, silica gel, and aluminosilicates as well as newly emerging adsorbents such as metal organic frameworks, graphene oxides, and waste-derived materials are studied in detail in terms of reusability and water tolerance. Although activated carbon is commercially used, its low selectivity, pore blockage due to siloxane polymerization, and unsuccessful regeneration make it disadvantageous. Silica gel, however, shows better reusability as a result of less adsorbent-adsorbate dissociation energy. In addition, aluminosilicates, despite its low adsorption capacity, proved to be more practical for real biogas due to their high hydrophobicity. Graphene oxide cost and energy efficiency in their synthesis make them more industrially appealing candidates despite their low adsorption capacity. Finally, metal organic frameworks demonstrated high selectivity, high adsorption capacity, and more efficient regeneration and therefore have more advantages and less drawbacks, although the number of published studies is still limited

    Effects of Preemptive and Preventive intravenous Paracetamol on postoperative pain and opioid consumption in patients undergoing laparoscopic nephrectomy

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    Background: Adequate pain control is a goal in post operative recovery. However opioids provide good analgesic effects, their side effects such as postoperative nausea and vomiting (PONV) limit their administration. Intravenous Paracetamol as a safe and well tolerated drug with lower side effects can be used instead of opioids for pain management.Objectives: The aim of this study is to compare preemptive or preventive administration of paracetamol with placebo group to investigate its effects on pain control and opioid consumption in patients undergoing laparoscopic nephrectomy.Patients and Methods: Ninety patients were randomly divided to three groups. Preemptive group received 1 gr paracetamol in 100 ml normal saline 30 minutes before induction of anesthesia, Preventive group received 1 gr paracetamol in 100 ml normal saline before closure of the skin and placebo group just received 100 ml normal saline. Post surgical pain was assessed using Verbal Rating Scale (VRS). Pethidine 0.25 mg/kg was administered and repeated each 10 minutes to control pain. Pain scores, total dose of opioid and symptoms like nausea and vomiting were recorded. Results: Preemptive and Preventive groups had lower pain scores than placebo group. Opioid consumption and PONV were significantly higher in placebo group. No significant differences were observed between Preemptive and Preventive groups.Conclusion: IV Paracetamol can provide an adequate pain control with low side effects and may be an effective choice in management of post operative pain in patients undergoing laparoscopic nephrectom

    The Effective Factors on the Formation of Scrap Learning in In-Service Training: A qualitative study

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    Introduction: In training courses, all the materials learned will not always be transmitted to the workplace because of some effective factors. The aim of this study was to determine the effective factors on the formation of scrap learning in in-service training. Method: This descriptive qualitative study was conducted using conventional content analysis. Data were collected using semi-structured interviews. The participants were all employees and workers of the copper industry in Kerman province. According to the data saturation level, 16 of them were selected using purposive sampling. Data were analyzed using qualitative content analysis. The validity of the research findings was confirmed using assessment methods by members and multi-stratified data sources. Results: The effective factors on the formation of scrap learning were classified into three categories: individual factors (attitude, learner readiness, professional ethics, and motivation), organizational factors (organizational support and working environment conditions), and educational factors (need assessment and evaluation, training strategies, and content of the course). Conclusion: Regardless of the attitude, motivation, and professional ethics of the participants, the lack of attention to their readiness for learning, lack of necessary support, lack of facilities and equipment, lack of attention to the employees' needs, and the results of evaluations are the most important factors that prohibit the application of the materials learned in the workplace. Keywords: Scrap learning, In-service training courses, Employees, Kerman copper industry, Qualitative researc

    Sensing of Alzheimer’s Disease and Multiple Sclerosis Using Nano-Bio Interfaces

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    It is well understood that patients with different diseases may have a variety of specific proteins (e.g., type, amount, and configuration) in their plasmas. When nanoparticles (NPs) are exposed to these plasmas, the resulting coronas may incorporate some of the disease-specific proteins. Using gold (Au) NPs with different surface properties and corona composition, we have developed a technology for the discrimination and detection of two neurodegenerative diseases, Alzheimer's disease (AD) and multiple sclerosis (MS). Applying a variety of techniques, including UV-visible spectra, colorimetric response analyses and liquid chromatography-tandem mass spectrometry, we found the corona-NP complexes, obtained from different human serums, had distinct protein composition, including some specific proteins that are known as AD and MS biomarkers. The colorimetric responses, analyzed by chemometrics and statistical methods, demonstrate promising capabilities of the technology to unambiguously identify and discriminate AD and MS. The developed colorimetric technology might enable a simple, inexpensive and rapid detection/discrimination of neurodegenerative diseases. KEYWORDS: Alzheimer’s disease; colorimetric technology; disease-specific protein corona; gold nanoparticles; multiple sclerosi

    Burden of cancer in the Eastern Mediterranean Region, 2005-2015: findings from the Global Burden of Disease 2015 Study

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    Fitzmaurice C, Alsharif U, El Bcheraoui C, et al. Burden of cancer in the Eastern Mediterranean Region, 2005-2015: findings from the Global Burden of Disease 2015 Study. INTERNATIONAL JOURNAL OF PUBLIC HEALTH. 2018;63(Suppl. 1):151-164.To estimate incidence, mortality, and disability-adjusted life years (DALYs) caused by cancer in the Eastern Mediterranean Region (EMR) between 2005 and 2015. Vital registration system and cancer registry data from the EMR region were analyzed for 29 cancer groups in 22 EMR countries using the Global Burden of Disease Study 2015 methodology. In 2015, cancer was responsible for 9.4% of all deaths and 5.1% of all DALYs. It accounted for 722,646 new cases, 379,093 deaths, and 11.7 million DALYs. Between 2005 and 2015, incident cases increased by 46%, deaths by 33%, and DALYs by 31%. The increase in cancer incidence was largely driven by population growth and population aging. Breast cancer, lung cancer, and leukemia were the most common cancers, while lung, breast, and stomach cancers caused most cancer deaths. Cancer is responsible for a substantial disease burden in the EMR, which is increasing. There is an urgent need to expand cancer prevention, screening, and awareness programs in EMR countries as well as to improve diagnosis, treatment, and palliative care services

    Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

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    Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to end preventable child deaths by 2030—we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000–2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained rates of 25 or fewer child deaths per 1,000 live births by 2017, and that 58% of child deaths between 2000 and 2017 in these countries could have been averted in the absence of geographical inequality. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations

    Mapping child growth failure across low- and middle-income countries

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    Child growth failure (CGF), manifested as stunting, wasting, and underweight, is associated with high 5 mortality and increased risks of cognitive, physical, and metabolic impairments. Children in low- and middle-income countries (LMICs) face the highest levels of CGF globally. Here we illustrate national and subnational variation of under-5 CGF indicators across LMICs, providing 2000–2017 annual estimates mapped at a high spatial resolution and aggregated to policy-relevant administrative units and national levels. Despite remarkable declines over the study period, many LMICs remain far from the World Health 10 Organization’s ambitious Global Nutrition Targets to reduce stunting by 40% and wasting to less than 5% by 2025. Large disparities in prevalence and rates of progress exist across regions, countries, and within countries; our maps identify areas where high prevalence persists even within nations otherwise succeeding in reducing overall CGF prevalence. By highlighting where subnational disparities exist and the highest-need populations reside, these geospatial estimates can support policy-makers in planning locally 15 tailored interventions and efficient directing of resources to accelerate progress in reducing CGF and its health implications

    Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2.5 air pollution, 1990-2019 : an analysis of data from the Global Burden of Disease Study 2019

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    Background Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2.5 originating from ambient and household air pollution.Methods We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM2.5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure-response curve from the extracted relative risk estimates using the MR-BRT (meta-regression-Bayesian, regularised, trimmed) tool. The estimated curve was linked to ambient and household PM2.5 exposures from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, and estimates of the attributable burden (population attributable fractions and rates per 100 000 population of deaths and disability-adjusted life-years) for 204 countries from 1990 to 2019 were calculated. We also assessed the role of changes in exposure, population size, age, and type 2 diabetes incidence in the observed trend in PM2.5-attributable type 2 diabetes burden. All estimates are presented with 95% uncertainty intervals.Findings In 2019, approximately a fifth of the global burden of type 2 diabetes was attributable to PM2.5 exposure, with an estimated 3.78 (95% uncertainty interval 2.68-4.83) deaths per 100 000 population and 167 (117-223) disability-adjusted life-years (DALYs) per 100 000 population. Approximately 13.4% (9.49-17.5) of deaths and 13.6% (9.73-17.9) of DALYs due to type 2 diabetes were contributed by ambient PM2.5, and 6.50% (4.22-9.53) of deaths and 5.92% (3.81-8.64) of DALYs by household air pollution. High burdens, in terms of numbers as well as rates, were estimated in Asia, sub-Saharan Africa, and South America. Since 1990, the attributable burden has increased by 50%, driven largely by population growth and ageing. Globally, the impact of reductions in household air pollution was largely offset by increased ambient PM2.5.Interpretation Air pollution is a major risk factor for diabetes. We estimated that about a fifth of the global burden of type 2 diabetes is attributable PM2.5 pollution. Air pollution mitigation therefore might have an essential role in reducing the global disease burden resulting from type 2 diabetes. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.Peer reviewe

    Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2.5 air pollution, 1990-2019 : An analysis of data from the Global Burden of Disease Study 2019

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    Background Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2·5 originating from ambient and household air pollution. Methods We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM2·5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure–response curve from the extracted relative risk estimates using the MR-BRT (meta-regression—Bayesian, regularised, trimmed) tool. The estimated curve was linked to ambient and household PM2·5 exposures from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, and estimates of the attributable burden (population attributable fractions and rates per 100 000 population of deaths and disability-adjusted life-years) for 204 countries from 1990 to 2019 were calculated. We also assessed the role of changes in exposure, population size, age, and type 2 diabetes incidence in the observed trend in PM2·5-attributable type 2 diabetes burden. All estimates are presented with 95% uncertainty intervals. Findings In 2019, approximately a fifth of the global burden of type 2 diabetes was attributable to PM2·5 exposure, with an estimated 3·78 (95% uncertainty interval 2·68–4·83) deaths per 100 000 population and 167 (117–223) disability-adjusted life-years (DALYs) per 100 000 population. Approximately 13·4% (9·49–17·5) of deaths and 13·6% (9·73–17·9) of DALYs due to type 2 diabetes were contributed by ambient PM2·5, and 6·50% (4·22–9·53) of deaths and 5·92% (3·81–8·64) of DALYs by household air pollution. High burdens, in terms of numbers as well as rates, were estimated in Asia, sub-Saharan Africa, and South America. Since 1990, the attributable burden has increased by 50%, driven largely by population growth and ageing. Globally, the impact of reductions in household air pollution was largely offset by increased ambient PM2·5. Interpretation Air pollution is a major risk factor for diabetes. We estimated that about a fifth of the global burden of type 2 diabetes is attributable PM2·5 pollution. Air pollution mitigation therefore might have an essential role in reducing the global disease burden resulting from type 2 diabetes
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