Una Nueva Metodología Para El Análisis Palinológico De Muestras Coprológicas En Vertebrados Polinizadores A New Methodology For The Palynological Analysis Of Feces

We described a method to analyze pollen samples from nectarivore bats’ hez. With this protocol is possible to extract the grain of pollen without strong chemicals and in a less time. We present the advantages this protocol has in front of conventional techniques used to carry out palynologycal analysis.Describimos un método para analizar muestras de polen en heces de murciélagos nectarívoros, optimizando el análisis palinológico sin el uso de químicos fuertes y en menor tiempo, demostrando las ventajas de nuestro protocolo frente a las técnicas convencionales de análisis de dietas de animales nectarívoros

Palinomorfos del cuaternario sobre el valle del rio san eugenio (risaralda, colombia)

Quantitative analysis of the palynological observations in an archaeological settlement between Late Pleistocene to Early Holocene in Santa Rosa de Cabal, Risaralda Colombia. A total of 71 samples were analysed over volcanic soils La pochola01 (47 samples) and La pochola02 (25 samples). The radiocarbon result dated the oldest simple which is 13.540±60 years B.P in the 105 cm (Late Pleistocene) and the earliest simple which was 6743±45 years B.P in the 57 cm, (Early Holocene). Diversified, well preserved palynofloras were recognized. A total of 61 species were described, including species of the, Pteridophytos (11 species), Pinopsida (1species) and Angiosperm (50species). This paper aims to contribute an increase to the knowledge of the Quaternary palynoflora in the middle Cauca.Un análisis cualitativo de las observaciones palinológicas realizadas sobre un yacimiento arqueológico entre el Pleistoceno tardío hasta el Holoceno temprano sobre Santa rosa de Cabal, Risaralda Colombia fue llevado a cabo como parte de una reconstrucción paleoecológica, dentro de la cual se analizaron un total de 71 muestras a partir de dos núcleos suelos volcánicos, La pochola 01 (47 muestras) y la pochola 02 (25 muestras).Con base en los datos de 14C obtenidos de la Pochola 01 se pudo establecer que la edad más antigua es de 13.540±60 años A.P, en los 105 cm (Pleistoceno tardío) y la edad más reciente 6743±45 años a.P en los 57 cm, (Holoceno medio). Los resultados muestran que la preservación de los granos de polen en suelos volcánicos es alta,la diversidad y buena preservación. Un total de 67 especies fueron descritas dentro de las cuales se encuentran representantes de clases, Pteridophytos (11 especies), Pinopsida (1especies) y Angiospermas (50 especies).Mediante este documento se pretende incrementar y contribuir al conocimiento palinológico del Cuaternario en la región del Cauca Medio

Wireless wine: estimación de rendimiento y ubicación de sensores para la predicción de heladas en los viñedos

Los productores de viñedos han estado reuniendo información operacional significativa sobre sus campos, y las fincas más avanzadas pueden producir varios años de datos sobre cómo se ha plantado, regado, fertilizado y cómo han madurado las uvas. A pesar de esta riqueza de datos operacionales, hoy en día no existe ninguna herramienta que pueda complementar y gestionar eficientemente estos datos para (1) proporcionar una previsión precisa del rendimiento y (2) predecir los efectos destructivos de los eventos de heladas. La previsión del rendimiento es el proceso para estimar la cantidad de producción de uva para cada sección de un campo en términos de kilos por unidad de superficie. El primer objetivo de WirelessWine es desarrollar una solución basada en el “aprendizaje de máquinas” lista para usar, que combine la riqueza de la información operativa de los productores, los datos meteorológicos regionales, las estaciones meteorológicas a nivel de campo y los dispositivos de IoT desplegados directamente en el campo para proporcionar una previsión precisa del rendimiento. En la región de Mendoza, las heladas han hecho que la producción de uva de 2016 sea un 40% inferior a la de 2015. Los productores pueden combatir un evento de heladas calentando el campo, pero tienen que saber que el evento de heladas viene con un par de horas de anticipación. Los pronósticos meteorológicos a escala regional no proporcionan la precisión necesaria para predecir de manera fiable los eventos de heladas. El segundo objetivo del WirelessWine es identificar, de forma iterativa, la ubicación de los sensores (en el follaje, en el racimo, a diferentes alturas, etc.) que permite la predicción más precisa del evento de helada.EEA MendozaFil: Dujovne, Diego. Universidad Diego Portales. Facultad de Ingeniería. Escuela de Informática y Telecomunicaciones; ChileFil: Watteyne, Thomas. Institut National de Recherche en Informatique et en Automatique (INRIA); FranciaFil: Mercado, Gustavo. Universidad Tecnológica Nacional. Facultad Regional Mendoza. Grupo en Tecnologías de la Información y las Comunicaciones Departamento de Electrónica (GridTICs); ArgentinaFil: Diedrichs, Ana. Universidad Tecnológica Nacional. Facultad Regional Mendoza. Grupo en Tecnologías de la Información y las Comunicaciones Departamento de Electrónica (GridTICs); ArgentinaFil: Taffernaberry, Juan Carlos. Universidad Tecnológica Nacional. Facultad Regional Mendoza. Grupo en Tecnologías de la Información y las Comunicaciones Departamento de Electrónica (GridTICs); ArgentinaFil: Perez Peña, Jorge Esteban. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Mendoza; Argentin

Respuesta de 10 cultivares de maíz a la densidad de población en tres localidades del centro mexiquense

SE LOGRÓ ESTABLECER LA RESPUESTA DE 10 CULTIVARES DE MAÍZ A LA DENSIDAD DE POBLACIÓN EN TRES LOCALIDADES DEL CENTRO DEL ESTADO DE MÉXICO.La densidad de población es uno de los principales factores que contribuyen a incrementar el rendimiento de grano en maíz. El presente trabajo se estableció en 2013 en tres localidades del centro del Estado de México, México para evaluar el rendimiento de grano y sus componentes principales en diez cultivares de maíz en tres densidades de población. Los tres ensayos se establecieron en campo en un diseño experimental de bloques completos al azar con tres repeticiones en un arreglo de parcelas divididas: en las parcelas grandes se distribuyeron las densidades de población y en las chicas los cultivares. Hubo diferencias significativas (p= 0.01) entre cultivares en las 13 variables registradas, en densidad de población éstas lo fueron en longitud de mazorca, diámetro de mazorca, peso de olote, peso de grano por planta, y rendimiento de grano. Un incremento en la densidad de población disminuyó el número y el peso de grano por planta pero a 104 167 plantas ha-1 el rendimiento fue de10.03 t ha-1. Con P204W se obtuvo la mayor producción de grano (10 t ha-1), pero éste no difirió estadísticamente de IC 2010, AS-MJ9082, H-40 y AS-723. El análisis de componentes principales explicó 65.94% de la variación total original, en éste se observó una alta correlación entre rendimiento de grano, granos por planta, índice de prolificidad y peso de olote

Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen

Drug-induced liver injury (DILI) development is commonly associated with acetaminophen (APAP) overdose, where glutathione scavenging leads to mitochondrial dysfunction and hepatocyte death. DILI is a severe disorder without effective late-stage treatment, since N-acetyl cysteine must be administered 8 h after overdose to be efficient. Ammonia homeostasis is altered during liver diseases and, during DILI, it is accompanied by decreased glycine N-methyltransferase (GNMT) expression and S-adenosylmethionine (AdoMet) levels that suggest a reduced methionine cycle. Anti-miR-873-5p treatment prevents cell death in primary hepatocytes and the appearance of necrotic areas in liver from APAP-administered mice. In our study, we demonstrate a GNMT and methionine cycle activity restoration by the anti-miR-873-5p that reduces mitochondrial dysfunction and oxidative stress. The lack of hyperammoniemia caused by the therapy results in a decreased urea cycle, enhancing the synthesis of polyamines from ornithine and AdoMet and thus impacting the observed recovery of mitochondria and hepatocyte proliferation for regeneration. In summary, anti-miR-873-5p appears to be an effective therapy against APAP-induced liver injury, where the restoration of GNMT and the methionine cycle may prevent mitochondrial dysfunction while activating hepatocyte proliferative response.We thank Ministerio de Ciencia e Innovación, Programa Retos-Colaboración RTC2019- 007125-1 (for J.S. and M.L.M.-C.); Instituto de Salud Carlos III: Proyectos de Investigación en Salud DTS20/00138 (for J.S. and M.L.M.-C.), PI20/00690 (for R.J.) and PT20/000127 (for M.I.L.); CIBERehd: EHD21TRF01/2022 (to M.L.M.-C.); Departamento de Industria del Gobierno Vasco (for M.L.M.-C.); Ministerio de Ciencia, Innovación y Universidades MICINN: PID2020-117116RB-I00 and RTI2018- 096759-1-100 integrado en el Plan Estatal de Investigación Cientifica y Técnica y Innovación, cofinanciado con Fondos FEDER (for M.L.M.-C. and T.C.D., respectively); BIOEF (Basque Foundation for Innovation and Health Research); Asociación Española contra el Cáncer (AECC) (to M.L.M.-C., T.C.D.); AECC: GCTRA18006CARR (to A.C.); Fundación Científica de la Asociación Española Contra el Cancer (AECC Scientific Foundation) Rare Tumor Calls 2017 (for M.L.M.); La Caixa Foundation Program (for M.L.M.); BFU2015-70067-REDC, BFU2016-77408-R and BES-2017-080435 (MINECO/FEDER, UE); Ministerio de Ciencia, Innovación y universidades PID2019-108787RB-100 (to A.C.), PID2019- 109055RB-I00 (L.A.M.-C.), PID2020-117941RB-100 (to F.J.C.); Spanish Ministry of Economy and Competitiveness Grants BFU2013-47531-R and BFU2016-77408-R (L.A.M.-C.) and the FIGHT-CNNM2 project from the EJP RD Joint Transnational Call (JTC2019) (Ref. AC19/00073) (for L.A.M.-C.); Comunidad de Madrid: EXOHEP-CM S2017/BMD-3727 and NanoLiver-CM Y2018/NMT-4949 co-funded by European Structural and Investment Fund and COST Action CA17112 (to F.J.C.); Vencer el Cáncer Foundation (to A.C.); European Research Council: Consolidator Grant 819242 (to A.C.); CIBERONC and CIBERehd were funded by the Instituto de Salud Carlos III and Cofunded by FEDER funds. Partial funding for open access charge: Universidad de Málag

Psychosocial risk profiles to address future health emergencies: a country study during the COVID-19 lockdown period in Colombia

IntroductionThe different strategies used worldwide to curb the COVID-19 pandemic between 2020 and 2021 had a negative psychosocial impact, which was disproportionately higher for socially and economically vulnerable groups. This article seeks to identify the psychosocial impact of the confinement period during the COVID-19 pandemic for the Colombian population by identifying profiles that predict the levels of different mental health indicators (feelings of fear, positive emotions or feelings during free time, and work impact) and based on them, characterize the risk factors and protection that allows us to propose guidelines for prevention or recovery from future health emergencies.MethodsThis is an observational, cross-sectional, retrospective ex post facto study. Multistage cluster probabilistic sampling and binary logistic regression analysis were used to predict extreme levels of various mental health indicators based on psychosocial indicators of the COVID-19 confinement period and to identify risk and protection factors,ResultsA relationship was established between the combination of some of the different psychosocial factors evaluated (this combination being the predictive profile identified) with each of the three main variables: feeling of fear (n = 8,247; R = 0.32; p = 0.00; Poverall = 62.4%; overall = 0.25; 1-overall = 1.00), positive emotions or feelings during free time (n = 6,853; R = 0.25; p = 0.00; Poverall = 59.1%; overall = 0.18; 1-overall = 1.00) and labour impact (n = 4,573; R = 0.47; p = 0.63; Poverall = 70.4%; overall = 0.41; 1-overall = 1.00), with social vulnerability determined by sociodemographic factors that were common in all profiles (sex, age, ethnicity and socioeconomic level) and conditions associated with job insecurity (unemployed, loss of health insurance and significant changes to job’s requirements) and place of residence (city).ConclusionFor future health emergencies, it is necessary to (i) mitigate the socio-employment impact from emergency containment measures in a scaled and differentiated manner at the local level, (ii) propose prevention and recovery actions through psychosocial and mental health care accessible to the entire population, especially vulnerable groups, (iii) Design and implement work, educational and recreational adaptation programs that can be integrated into confinement processes

Azimuthal anisotropy of charged jet production in root s(NN)=2.76 TeV Pb-Pb collisions

We present measurements of the azimuthal dependence of charged jet production in central and semi-central root s(NN) = 2.76 TeV Pb-Pb collisions with respect to the second harmonic event plane, quantified as nu(ch)(2) (jet). Jet finding is performed employing the anti-k(T) algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero nu(ch)(2) (jet) is observed in semi-central collisions (30-50% centrality) for 20 <p(T)(ch) (jet) <90 GeV/c. The azimuthal dependence of the charged jet production is similar to the dependence observed for jets comprising both charged and neutral fragments, and compatible with measurements of the nu(2) of single charged particles at high p(T). Good agreement between the data and predictions from JEWEL, an event generator simulating parton shower evolution in the presence of a dense QCD medium, is found in semi-central collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe

Forward-central two-particle correlations in p-Pb collisions at root s(NN)=5.02 TeV

Two-particle angular correlations between trigger particles in the forward pseudorapidity range (2.5 2GeV/c. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B. V.Peer reviewe

Event-shape engineering for inclusive spectra and elliptic flow in Pb-Pb collisions at root(NN)-N-S=2.76 TeV

Peer reviewe

Outcomes of elective liver surgery worldwide: a global, prospective, multicenter, cross-sectional study

Background: The outcomes of liver surgery worldwide remain unknown. The true population-based outcomes are likely different to those vastly reported that reflect the activity of highly specialized academic centers. The aim of this study was to measure the true worldwide practice of liver surgery and associated outcomes by recruiting from centers across the globe. The geographic distribution of liver surgery activity and complexity was also evaluated to further understand variations in outcomes. Methods: LiverGroup.org was an international, prospective, multicenter, cross-sectional study following the Global Surgery Collaborative Snapshot Research approach with a 3-month prospective, consecutive patient enrollment within January–December 2019. Each patient was followed up for 90 days postoperatively. All patients undergoing liver surgery at their respective centers were eligible for study inclusion. Basic demographics, patient and operation characteristics were collected. Morbidity was recorded according to the Clavien–Dindo Classification of Surgical Complications. Country-based and hospital-based data were collected, including the Human Development Index (HDI). (NCT03768141). Results: A total of 2159 patients were included from six continents. Surgery was performed for cancer in 1785 (83%) patients. Of all patients, 912 (42%) experienced a postoperative complication of any severity, while the major complication rate was 16% (341/2159). The overall 90-day mortality rate after liver surgery was 3.8% (82/2,159). The overall failure to rescue rate was 11% (82/ 722) ranging from 5 to 35% among the higher and lower HDI groups, respectively. Conclusions: This is the first to our knowledge global surgery study specifically designed and conducted for specialized liver surgery. The authors identified failure to rescue as a significant potentially modifiable factor for mortality after liver surgery, mostly related to lower Human Development Index countries. Members of the LiverGroup.org network could now work together to develop quality improvement collaboratives