19 research outputs found
SOME RISK MANAGEMENT PRACTICES AMONG THE BEEF CATTLE FARMERS OF THE NORTH WEST PROVINCE OF CAMEROON: EFFECT ON TECHNOLOGY DISSEMINATION
The North West Province of Cameroon is one of the four provinces that account for 90 % of Cameroon's estimated 6 million cattle heads. The cattle production in the area involves the rural poor population who are associated with a reluctance to take risks, presumably because risk taking would jeopardize their subsistence. That being the case, it becomes imperative to know what risk management methods they use. The overall objective of this study was to identify and examine the risk management practiced by the beef cattle farmers in the North West Province of Cameroon so as to determine their effects on technology dissemination. The beef cattle farmers were selected for the survey on the basis of their involvement in beef cattle farming. The researchers visited the selected farmers at their homesteads / farmsteads to collect the required information using a structured questionnaire. Quantitative data were analyzed using simple descriptive statistics while qualitative ones were analyzed using percentages and frequency counts. Eighty one percent of the respondents followed a mixed agro pastoral strategy in which cattle production was combined with crop farming. More than 90 % of the respondents had secondary economic activities other than crop farming. This is a major means of spreading risk across economic sectors and geographical space, and securing alternative sources of income. Sixty five percent of the respondents go on transhumance during the dry season for search of water and pasture for their animals. The cattle farmers relied on the use of their traditional cattle species that are more drought and disease resistant. Cattle and small ruminants were kept by more than 60 % of the respondents, subdivided into herds for risk avoidance, proper management and hand deticking.Livestock Production/Industries, Risk and Uncertainty,
Obesity phenotypes in urban and rural Cameroonians: a cross-sectional study
BACKGROUND: Despite the increasing prevalence of diabetes and other health consequences of obesity, little is known on the metabolic profile across categories of body mass index (BMI) among African populations. We therefore assessed the prevalence and distribution of body size phenotypes among urban and rural Cameroonians. METHODS: Adults (n=1628; 41% rural dwellers) aged 24-74 years in 1994 provided data on BMI and metabolic health, defined on the basis of elevated levels of blood pressure (BP); triglycerides, fasting plasma glucose (FPG), and insulin resistance as assessed with homeostasis model assessment (HOMA). Cross-classification of BMI categories and metabolic status (healthy/unhealthy) created six groups. Metabolic measures include elevated blood pressure; elevated triglycerides ([greater than or equal to]150 mg/dL or 1.69mmo/L), elevated fasting plasma glucose ([greater than or equal to]100 mg/dl or 5.6 mmol/L or documented use of antidiabetic medications), and elevated homeostasis model assessment of insulin resistance value (HOMA-IR>90th percentile). RESULTS: A total of 25.2% of participants were overweight yet metabolically healthy (<1 abnormality) and 10.1% were obese yet metabolically healthy, whereas 1.4% were normal weight but metabolically abnormal ([greater than or equal to]2 abnormalities). Proportion of rural dwellers with abnormal metabolic phenotype across normal-weight, overweight, obese categories were 2.9%, 0.8% and 0.3%, respectively; and 0 .3%, 2.2% and 2.6% among urban dwellers. Metabolically abnormal participants increased linearly across BMI categories (p<0.001). BMI categories and metabolic status interacted to affect age, gender, BMI, FPG, triglycerides, and BP status distributions (all p<0.04). Metabolic status and residence (rural vs. urban) interacted to influence the distribution across BMI categories of diastolic BP, BMI, waist circumference, fasting and 2-hour glucose, triglycerides, HOMA-IR, and prevalent diabetes (all p<0.005), with differential occurrence of BMI categories and metabolic status among urban and rural participants. CONCLUSIONS: Metabolic healthy obesity and obesity with a favorable cardiometabolic profile are not uncommon among Cameroonians, including among rural dwellers; but the latter group tended to have a better profile
Harnessing Schistosoma -associated metabolite changes in the human host to identify biomarkers of infection and morbidity: where are we and what should we do next?
Schistosomiasis is the second most widespread parasitic disease affecting humans. A key component of today’s infection control measures is the diagnosis and monitoring of infection, informing individual- and community-level treatment. However, newly acquired infections and/or low parasite burden are still difficult to diagnose reliably. Furthermore, even though the pathological consequence of schistosome egg sequestration in host tissues is well described, the evidence linking egg burden to morbidity is increasingly challenged, making it inadequate for pathology monitoring. In the last decades, omics-based instruments and methods have been developed, adjusted, and applied in parasitic research. In particular, the profiling of the most reliable determinants of phenotypes, metabolites by metabolomics, emerged as a powerful boost in the understanding of basic interactions within the human host during infection. As such, the fine detection of host metabolites produced upon exposure to parasites such as Schistosoma spp. and the ensuing progression of the disease are believed to enable the identification of Schistosoma spp. potential biomarkers of infection and associated pathology. However, attempts to provide such a comprehensive understanding of the alterations of the human metabolome during schistosomiasis are rare, limited in their design when performed, and mostly inconclusive. In this review, we aimed to briefly summarize the most robust advances in knowledge on the changes in host metabolic profile during Schistosoma infections and provide recommendations for approaches to optimize the identification of metabolomic signatures of human schistosomiasis
Effect of pre-partum feed supplementation on post-partum ovarian activity, milk production and calf growth of small holder dairy cattle in Cameroon
Seventy-two cows were selected for an on-farm
study on the effect of feed supplementation before calving
on milk production, ovarian activity and calf growth of
Holstein, indigenous Red Fulani cows and their crosses. Prepartum
feed supplementation was done using cotton seed cake
(80 %), maize (18 %), bone meal (1 %) and kitchen salt (1 %
NaCl). Supplementation levels consisted of a low supplementation
fed at 1 kg per animal per day and high supplementation
fed at 2 kg per animal per day. In addition, Red Fulani cows
received the supplements in two different ways namely a prepartum
supplementation consisting of 1 kg per cow per day
and pre- and post-partum supplementation consisting of 1 kg
per cow per day before calving and 1 kg per cow per day postpartum
up to 30 days after calving. Blood samples were
analysed using ELISA Progesterone kits to determine the
length of post-partum anoestrus. Results show that prepartum
levels of feeding did not have any effect (P>0.05)
on body condition score (BCS) at 12 weeks after calving, calf
birth weight, average daily weight gain of calves, milk production
and post-partum anoestrus. High BCS at calving was
shown to influence BCS at 12 weeks of lactation. Holstein
cows had bigger calves (P<0.01) at birth (45 kg) compared to
traditional cows (36 kg) and crosses (34 kg). There was little
benefit of pre-partum supplementation on the parameters investigated
in this study. Consequently, low income farmers are
advised to concentrate their efforts of supplementation early in
lactation.The International
Atomic Energy Agency (IAEA) and the African Development Bank.http://link.springer.com/journal/112502015-10-30hj201
Effect of cow parity and synchronization method with PGF2α on conception rates of Bos indicus cows in Cameroon
The objective of this work was to evaluate the
effect of two synchronization methods with prostaglandins
F2α (PGF2α) on heifers and multiparous cows. Fourty-three
Bos indicus cows (white and Red Fulani) were divided into
four groups in a two-by-two factorial structure, parity x method
of synchronization. The synchronization methods
consisted of a two-dose regime which involved injection of
animals on day 0 with PGF2α (Lutalyse) at 5 ml per cow
intramuscularly. On day 11, the injection was repeated at the
same dosage. On day 14 (72 h after the second injection), a
fixed-time artificial insemination (AI) was done. On day 15
(96 h after the second injection), a second insemination was
done. The one-and-a-half-dose regime consisted of an injection
similar to the first treatment mentioned above on day 0.
Thereafter, cows were observed for heat, and anyone showing
heat was inseminated. A second dose was given on day 11 to
all animals not having shown any heat. A fixed-time AI was
done on days 14 and 15. Blood samples were collected on the
day 0 of insemination for each cow while day 11 and day 21
after insemination. Progesterone was analysed by means of standard ELISA progesterone kits to determine its profiles
after insemination. Results show no evidence of the effect of
treatments on conception rates (P>0.05). Similarly, heifers
and multiparous cows had similar conception rates
(P>0.05). Between 3 weeks and 3 months of pregnancy, there
was a loss of embryos of 28 % in heifers and 20 % in
multiparous cows, but the difference between the two groups
was not significant (P>0.05). It recommended that farmers do
not synchronize animals with poor body condition score
(BCS). They should also monitor weight gains of heifers,
remove them from the herd when they have been mixed with
young growing bulls and put them in a breeding herd. The
two-dose regime is better to be used in areas where the
inseminator cannot easily be available.http://link.springer.com/journal/112502016-01-31hb201
Fasting insulin sensitivity indices are not better than routine clinical variables at predicting insulin sensitivity among Black Africans: a clamp study in sub-Saharan Africans
BACKGROUND: We aimed to evaluate the predictive utility of common fasting insulin sensitivity indices, and non-laboratory surrogates [BMI, waist circumference (WC) and waist-to-height ratio (WHtR)] in sub-Saharan Africans without diabetes. METHODS: We measured fasting glucose and insulin, and glucose uptake during 80/mU/m2/min euglycemic clamp in 87 Cameroonians (51 men) aged (SD) 34.6 (11.4) years. We derived insulin sensitivity indices including HOMA-IR, quantitative insulin sensitivity check index (QUICKI), fasting insulin resistance index (FIRI) and glucose-to-insulin ratio (GIR). Indices and clinical predictors were compared to clamp using correlation tests, robust linear regressions and agreement of classification by sex-specific thirds. RESULTS: The mean insulin sensitivity was M =10.5+/-3.2mg/kg/min. Classification across thirds of insulin sensitivity by clamp matched with non-laboratory surrogates in 30-48% of participants, and with fasting indices in 27-51%, with kappa statistics ranging from 0.10 to 0.26. Fasting indices correlated significantly with clamp (/r/=0.23-0.30), with GIR performing less well than fasting insulin and HOMA-IR (both p <0.02). BMI, WC and WHtR were equal or superior to fasting indices (/r/=0.38-0.43). Combinations of fasting indices and clinical predictors explained 25-27% of variation in clamp values. CONCLUSION: Fasting insulin sensitivity indices are modest predictors of insulin sensitivity measured by euglycemic clamp, and do not perform better than clinical surrogates in this population
Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants
© The Author(s) 2018. Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean diastolic blood pressure (DBP) and prevalence of raised blood pressure by sex and 10-year age group from 20-29 years to 70-79 years in each study, taking into account complex survey design and survey sample weights, where relevant. We used a linear mixed effect model to quantify the association between (probittransformed) prevalence of raised blood pressure and age-group- and sex-specific mean blood pressure. We calculated the contributions of change in mean SBP and DBP, and of change in the prevalence-mean association, to the change in prevalence of raised blood pressure. Results: In 2005-16, at the same level of population mean SBP and DBP, men and women in South Asia and in Central Asia, the Middle East and North Africa would have the highest prevalence of raised blood pressure, and men and women in the highincome Asia Pacific and high-income Western regions would have the lowest. In most region-sex-age groups where the prevalence of raised blood pressure declined, one half or more of the decline was due to the decline in mean blood pressure. Where prevalence of raised blood pressure has increased, the change was entirely driven by increasing mean blood pressure, offset partly by the change in the prevalence-mean association. Conclusions: Change in mean blood pressure is the main driver of the worldwide change in the prevalence of raised blood pressure, but change in the high-blood-pressure tail of the distribution has also contributed to the change in prevalence, especially in older age groups
SOME RISK MANAGEMENT PRACTICES AMONG THE BEEF CATTLE FARMERS OF THE NORTH WEST PROVINCE OF CAMEROON: EFFECT ON TECHNOLOGY DISSEMINATION
The North West Province of Cameroon is one of the four provinces that account for 90 % of Cameroon's estimated 6 million cattle heads. The cattle production in the area involves the rural poor population who are associated with a reluctance to take risks, presumably because risk taking would jeopardize their subsistence. That being the case, it becomes imperative to know what risk management methods they use. The overall objective of this study was to identify and examine the risk management practiced by the beef cattle farmers in the North West Province of Cameroon so as to determine their effects on technology dissemination. The beef cattle farmers were selected for the survey on the basis of their involvement in beef cattle farming. The researchers visited the selected farmers at their homesteads / farmsteads to collect the required information using a structured questionnaire. Quantitative data were analyzed using simple descriptive statistics while qualitative ones were analyzed using percentages and frequency counts. Eighty one percent of the respondents followed a mixed agro pastoral strategy in which cattle production was combined with crop farming. More than 90 % of the respondents had secondary economic activities other than crop farming. This is a major means of spreading risk across economic sectors and geographical space, and securing alternative sources of income. Sixty five percent of the respondents go on transhumance during the dry season for search of water and pasture for their animals. The cattle farmers relied on the use of their traditional cattle species that are more drought and disease resistant. Cattle and small ruminants were kept by more than 60 % of the respondents, subdivided into herds for risk avoidance, proper management and hand deticking