661 research outputs found
Effect of human leukocyte antigen heterozygosity on infectious disease outcome: The need for allele-specific measures
- Author
- A Martin
- AV Hill
- AV Hill
- AVS Hill
- DJ Penn
- DJ Penn
- DL Hartl
- DM Williams
- DP McManus
- FJ Kallman
- J Tang
- JE McDonagh
- KJ Jeffery
- M Aidoo
- M Asti
- M Carrington
- M Carrington
- MR Thursz
- MS Kruskall
- MT Dorak
- N Takahata
- P Wordsworth
- PC Doherty
- PC Doherty
- PO Flores-Villanueva
- PW Hedrick
- PW Hedrick
- R McLeod
- RA Kaslow
- RA Kaslow
- RM Zinkernagel
- S Jean
- W van Eden
- Publication venue
- BioMed Central
- Publication date
- 01/01/2003
- Field of study
BACKGROUND: Doherty and Zinkernagel, who discovered that antigen presentation is restricted by the major histocompatibility complex (MHC, called HLA in humans), hypothesized that individuals heterozygous at particular MHC loci might be more resistant to particular infectious diseases than the corresponding homozygotes because heterozygotes could present a wider repertoire of antigens. The superiority of heterozygotes over either corresponding homozygote, which we term allele-specific overdominance, is of direct biological interest for understanding the mechanisms of immune response; it is also a leading explanation for the observation that MHC loci are extremely polymorphic and that these polymorphisms have been maintained through extremely long evolutionary periods. Recent studies have shown that in particular viral infections, heterozygosity at HLA loci was associated with a favorable disease outcome, and such findings have been interpreted as supporting the allele-specific overdominance hypothesis in humans. METHODS: An algebraic model is used to define the expected population-wide findings of an epidemiologic study of HLA heterozygosity and disease outcome as a function of allele-specific effects and population genetic parameters of the study population. RESULTS: We show that overrepresentation of HLA heterozygotes among individuals with favorable disease outcomes (which we term population heterozygote advantage) need not indicate allele-specific overdominance. On the contrary, partly due to a form of confounding by allele frequencies, population heterozygote advantage can occur under a very wide range of assumptions about the relationship between homozygote risk and heterozygote risk. In certain extreme cases, population heterozygote advantage can occur even when every heterozygote is at greater risk of being a case than either corresponding homozygote. CONCLUSION: To demonstrate allele-specific overdominance for specific infections in human populations, improved analytic tools and/or larger studies (or studies in populations with limited HLA diversity) are necessary
Surveillance of testicular microlithiasis?: Results of an UK based national questionnaire survey
- Author
- Publication venue
- BioMed Central
- Publication date
- 01/03/2006
- Field of study
BACKGROUND: The association of testicular microlithiasis with testicular tumour and the need for follow-up remain largely unclear. METHODS: We conducted a national questionnaire survey involving consultant BAUS members (BAUS is the official national organisation (like the AUA in USA) of the practising urologists in the UK and Ireland), to provide a snapshot of current attitudes towards investigation and surveillance of patients with testicular microlithiasis. RESULTS: Of the 464 questionnaires sent to the BAUS membership, 263(57%) were returned. 251 returns (12 were incomplete) were analysed, of whom 173(69%) do and 78(31%) do not follow-up testicular microlithiasis. Of the 173 who do follow-up, 119(69%) follow-up all patients while 54(31%) follow-up only a selected group of patients. 172 of 173 use ultra sound scan while 27(16%) check tumour makers. 10(6%) arrange ultrasound scan every six months, 151(88%) annually while 10(6%) at longer intervals. 66(38%) intend to follow-up these patients for life while, 80(47%) until 55 years of age and 26(15%) for up to 5 years. 173(68.9%) believe testicular microlithiasis is associated with CIS in < 1%, 53(21%) think it is between 1&10% while 7(3%) believe it is > 10%. 109(43%) believe those patients who develop a tumour, will have survival benefit with follow-up while 142(57%) do not. Interestingly, 66(38%) who follow-up these patients do not think there is a survival benefit. CONCLUSION: There is significant variability in how patients with testicular microlithiasis are followed-up. However a majority of consultant urologists nationally, believe surveillance of this patient group confers no survival benefit. There is a clear need to clarify this issue in order to recommend a coherent surveillance policy
The development and piloting of the graduate assessment of preparedness for practice (GAPP) questionnaire
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 23/09/2016
- Field of study
Introduction Most new dental graduates in the UK begin their professional career following a year in dental foundation training (DFT). There has been little investigation of how prepared they feel for independent general dental practice across all four domains of the General Dental Councilâs curriculum âPreparing for practiceâ. This paper describes the development of the Graduate Assessment of Preparedness for Practice (GAPP) questionnaire to address this. Methodology The GAPP questionnaire was developed and piloted using a cohort of educational supervisors (ESs) and foundation dentists (FDs). The questionnaire comprised three parts, the first of which collected respondent demographic data. The second was based on Preparing for practice and was used to develop 34 âcompetence areasâ and required a tick-box response on a 7âcategory Likert Scale. The third comprised free text questions in order to further explore the subjectâs responses. Results Pilot feedback was positive, the statements were felt to be clear and unambiguous, allowing them sufficient scope to state their position. The pilot study informed small cosmetic changes to the GAPP questionnaire and inclusion of a âcommentsâ column for respondents to qualify their responses. The pilot results indicated that both FDs and their ESs felt that at ten months of DFT, the FDs were very well prepared for independent general dental practice. Discussion The paper describes the important considerations relating to the reliability and validity of the GAPP questionnaire. Conclusions GAPP appears to be a suitable questionnaire to measure preparedness of new graduates with a degree of reliability and validity. The instrument is designed to be simple to complete and provides a useful analytical instrument for both self-assessment of competence and for wider use within dental education
Feelings of women after the diagnosis of type 2 diabetes
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
IL-15 Participates in the Respiratory Innate Immune Response to Influenza Virus Infection
- Author
- A Onu
- AC Hocke
- B Morandi
- CH Shen
- Charles J. Cole
- David L. Rose
- DL Woodland
- DW Chae
- E Assarsson
- E Vivier
- ED Kilbourne
- EF Castillo
- EF Castillo
- F Mattei
- FJ Kos
- FJ Kos
- George Kassiotis
- H Kobayashi
- J Barlic
- J McGill
- J Stein-Streilein
- JC Sun
- JE Crowe Jr
- JR Groom
- K Kitaya
- K Yamaji
- KA Benton
- Katherine C. Verbist
- KC Verbist
- KG Elpek
- KH Grabstein
- Kimberly D. Klonowski
- L Denney
- LP Ho
- LP Perera
- M Matrosovich
- Mary B. Field
- MK Kennedy
- N Azimi
- ND Huntington
- O Mandelboim
- P Allavena
- P Caufour
- PC Doherty
- R Ahmad
- R Gazit
- R Koka
- R Meazza
- RA Fouchier
- RJ Hogan
- RR Kulkarni
- S Dubois
- S Muro
- T Walzer
- TA Fehniger
- TA Stoklasek
- TI Arnon
- TM Doherty
- V Budagian
- W Allan
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
Following influenza infection, natural killer (NK) cells function as interim effectors by suppressing viral replication until CD8 T cells are activated, proliferate, and are mobilized within the respiratory tract. Thus, NK cells are an important first line of defense against influenza virus. Here, in a murine model of influenza, we show that virally-induced IL-15 facilitates the trafficking of NK cells into the lung airways. Blocking IL-15 delays NK cell entry to the site of infection and results in a disregulated control of early viral replication. By the same principle, viral control by NK cells can be therapeutically enhanced via intranasal administration of exogenous IL-15 in the early days post influenza infection. In addition to controlling early viral replication, this IL-15-induced mobilization of NK cells to the lung airways has important downstream consequences on adaptive responses. Primarily, depletion of responding NK1.1+ NK cells is associated with reduced immigration of influenza-specific CD8 T cells to the site of infection. Together this work suggests that local deposits of IL-15 in the lung airways regulate the coordinated innate and adaptive immune responses to influenza infection and may represent an important point of immune intervention
A multi-disciplinary education process related to the discharging of children from hospital when the child has been diagnosed with type 1 diabetes - a qualitative study
- Author
- A Mol
- A Wennick
- AB Lewin
- AM Delamater
- Anita Lundqvist
- C Pihoker
- C Webb
- D Kyne-Grzebalski
- DL Hatton
- FJ Cameron
- GA Forsander
- H Kyngas
- I Hallstrom
- I Hallstrom
- Inger Hallström
- J McDougal
- J Reed
- J Silverstein
- JA Ahern
- KL Lemanek
- L Lowes
- L Lowes
- L Nuutila
- Lisbeth Jönsson
- M Clayton
- M Grey
- MBD Ferri
- MMLL Carpentier
- NFCM Woods
- PG Swift
- RCMA Kreuger
- S Clement
- S Sjöblad
- SV Llahana
- T Simell
- TC Skinner
- UH Graneheim
- YJ Doherty
- Publication venue
- BioMed Central
- Publication date
- 01/01/2010
- Field of study
<p>Abstract</p> <p>Background</p> <p>Worldwide, insulin-dependent type 1 diabetes is one of the most frequently diagnosed long-term endocrine disorders found in children and the incidences of this diseased is still increasing. In Sweden the routines are, according to national guidelines, when the child is diagnosed with type 1 diabetes, the child and its family remains at the hospital for about two weeks. There is limited knowledge about how a diabetes team handles a child and its family from admission to discharge, therefore the purpose of this study was to seek a deeper understanding of how the diabetes team's parent/child education process works, from admission to discharge, among families with a child newly diagnosed with type 1 diabetes.</p> <p>Methods</p> <p>Qualitative data collection was used. Four focus-group interviews, with a sample of three diabetes teams from different paediatric hospitals in the south western part of Sweden, were conducted and the data recorded on tape and then analysed using qualitative content analysis.</p> <p>Results</p> <p>The results indicate that achieving a status of self-care on the part of the patient is the goal of the diabetes education programme. Part of the programme is aimed at guiding the child and its parents towards self-help through the means of providing them with knowledge of the disease and its treatment to enable the whole family to understand the need for cooperation in the process. To do this requires an understanding, by the diabetes team, of the individualities of the family in order to gain an overall picture.</p> <p>Conclusion</p> <p>The results of this study show that the diabetes education programme is specifically designed for each family using the internationally recommended clinical practice guidelines with its specific aims and objectives. Achieving the families' willingness to assist in the self-care of the child care is the goal of the parent education process. To achieve this, the paediatric diabetes specialist nurse and the diabetes specialist paediatrician immediately and deliberately start the process of educating the family using a programme designed to give them the necessary knowledge and skills they will need to manage their child's type 1 diabetes at home.</p
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogana T
- Akesson TPA
- Akimoto G
- Akimov AV
- Akiyama A
- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angerami A
- Anghinolfi F
- Anh TV
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Arce ATH
- Archambault JP
- Arfaoui S
- Arguin J-F
- Arik E
- Arik M
- Armbruster AJ
- Arnaez O
- Arnault C
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Asfandiyarov R
- Ask S
- Asman B
- Asner D
- Asquith L
- Assamagan K
- Astbury A
- Astvatsatourov A
- Atoian G
- Aubert B
- Auge E
- Augsten K
- Aurousseau M
- Austin N
- Avolio G
- Avramidou R
- Axen D
- Ay C
- Azuelos G
- Azuma Y
- Baak MA
- Baccaglioni G
- Bacci C
- Bach AM
- Bachacou H
- Bachas K
- Bachy G
- Backes M
- Backhaus M
- Badescu E
- Bagnaia P
- Bahinipati S
- Bai Y
- Bailey DC
- Bain T
- Baines JT
- Baker MD
- Baker OK
- Baker S
- Banas E
- Banerjee P
- Banerjee S
- Banfi D
- Bangert A
- Bansal V
- Bansil HS
- Barajas CAC
- Barak L
- Baranov SP
- Barashkou A
- Barber T
- Barberio EL
- Barberis D
- Barbero M
- Bardin DY
- Barillari T
- Barisonzi M
- Barklow T
- Barlow N
- Barnett BM
- Barnett RM
- Baroncelli A
- Barone G
- Barr AJ
- Barreiro F
- Barrera CO
- Barrillon P
- Bartoldus R
- Barton AE
- Bartsch D
- Bartsch V
- Bates RL
- Batkova L
- Batley JR
- Battaglia A
- Battistin M
- Battistoni G
- Bauer F
- Bawa HS
- Beare B
- Beau T
- Beauchemin PH
- Beccherle R
- Bechtle P
- Beck GA
- Beck HP
- Beckingham M
- Becks KH
- Beddall A
- Beddall AJ
- Bedikian S
- Bednyakov VA
- Bee CP
- Begel M
- Behera PK
- Beimforde M
- Belanger-Champagne C
- Belenguer MJ
- Bell PJ
- Bell WH
- Bella G
- Bella LA
- Bellagamba L
- Bellina F
- Bellomo M
- Belloni A
- Beloborodova O
- Belotskiy K
- Beltramello O
- Ben Ami S
- Benary O
- Benchekroun D
- Benchouk C
- Bendel M
- Benekos N
- Benhammou Y
- Benjamin DP
- Benoit M
- Bensinger JR
- Benslama K
- Bentvelsen S
- Beretta M
- Berge D
- Berger N
- Berghaus F
- Berglund E
- Beringer J
- Bernardet K
- Bernat P
- Bernhard R
- Bernius C
- Berry T
- Bertin A
- Bertinelli F
- Bertolucci F
- Besana MI
- Besson N
- Bethke S
- Bhimji W
- Bianchi RM
- Bianco M
- Biebel O
- Bieniek SP
- Bierwagen K
- Biesiada J
- Biglietti M
- Bilokon H
- Bindi M
- Binet S
- Bingul A
- Bini C
- Biscarat C
- Bitenc U
- Black KM
- Blair RE
- Blanchard J-B
- Blanchot G
- Blazek T
- Blocker C
- Blocki J
- Blondel A
- Blum W
- Blumenschein U
- Bobbink GJ
- Bobrovnikov VB
- Bocchetta SS
- Bocci A
- Boddy CR
- Boehler M
- Boek J
- Boelaert N
- Boeriu OEV
- Boeser S
- Bogaerts JA
- Bogdanchikov A
- Bogouch A
- Bohm C
- Boisvert V
- Bold T
- Boldea V
- Bolnet NM
- Bona M
- Bondarenko VG
- Bondioli M
- Boonekamp M
- Boorman G
- Booth CN
- Bordoni S
- Borer C
- Borisov A
- Borissov G
- Borjanovic I
- Borroni S
- Bos K
- Boscherini D
- Bosman M
- Boterenbrood H
- Botterill D
- Bouchami J
- Boudreau J
- Bouhova-Thacker EV
- Bourdarios C
- Bousson N
- Boveia A
- Boyd J
- Boyko IR
- Bozhko NI
- Bozovic-Jelisavcic I
- Bracinik J
- Braem A
- Branchini P
- Brandenburg GW
- Brandt A
- Brandt G
- Brandt O
- Bratzler U
- Brau B
- Brau JE
- Braun HM
- Brelier B
- Bremer J
- Brenner R
- Bressler S
- Breton D
- Britton D
- Brochu FM
- Brock I
- Brock R
- Brodbeck TJ
- Brodet E
- Broggi F
- Bromberg C
- Brooijmans G
- Brooks WK
- Brown G
- Brown H
- Bruncko D
- Bruneliere R
- Brunet S
- Bruni A
- Bruni G
- Bruschi M
- BScher V
- Buanes T
- Bucci F
- Buchanan J
- Buchanan NJ
- Buchholz P
- Buckingham RM
- Buckley AG
- Buda SI
- Budagov IA
- Budick B
- Bueso XP
- Bugge L
- Buira-Clark D
- Bulekov O
- Bunse M
- Buran T
- Burckhart H
- Burdin S
- Burgess T
- Burke S
- Busato E
- Bussey P
- Buszello CP
- Butin F
- Butler B
- Butler JM
- Buttar CM
- Butterworth JM
- Buttinger W
- Caballero J
- Caforio D
- Cakir IT
- Cakir O
- Calafiura P
- Calderini G
- Calfayan P
- Calkins R
- Caloba LP
- Caloi R
- Calvet D
- Calvet S
- Camarri P
- Cambiaghi M
- Cameron D
- Camilocci ES
- Campana S
- Campanelli M
- Canale V
- Canelli F
- Canepaa A
- Cantero J
- Capasso L
- Caprini I
- Caprini M
- Capriotti D
- Capua M
- Caputo R
- Caramarcu C
- Cardarelli R
- Carli T
- Carlino G
- Carminati L
- Caron B
- Caron S
- Carter AA
- Carter JR
- Carvalho J
- Casadei D
- Casado MP
- Cascella M
- Caso C
- Castaneda-Miranda E
- Castanheira MTD
- Castillo LRF
- Castro NF
- Cataldi G
- Cataneo F
- Catinaccio A
- Catmore JR
- Cattai A
- Cattani G
- Caughron S
- Cauz D
- Cavalcanti TP
- Cavalleri P
- Cavalli D
- Cavalli-Sforza M
- Cavasinni V
- Ceradini F
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cetin SA
- Cevenini F
- Chafaq A
- Chakraborty D
- Chan K
- Chapleau B
- Chapman JD
- Chapman JW
- Chareyre E
- Charlton DG
- Chavda V
- Cheatham S
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chelstowska MA
- Chen C
- Chen H
- Chen S
- Chen T
- Chen X
- Cheng S
- Cheong ALF
- Cheplakov A
- Chepurnov VF
- Chernyatin V
- Cheu E
- Cheung SL
- Chevalier L
- Chiefari G
- Chikovani L
- Childers JT
- Chilingarov A
- Chiodini G
- Chizhov MV
- Choudalakis G
- Chouridou S
- Christidi IA
- Christov A
- Chromek-Burckhart D
- Chu ML
- Chudoba J
- Ciapetti G
- Ciba K
- Ciftci AK
- Ciftci R
- Cinca D
- Cindro V
- Ciobotaru MD
- Cioccaa C
- Ciocio A
- Cirilli M
- Citterio M
- Ciubancan M
- Clark A
- Clark PJ
- Cleland W
- Clemens JC
- Clement B
- Clement C
- Clifft RW
- Coadou Y
- Cobal M
- Coccaro A
- Cochran J
- Codina EP
- Coe P
- Cogan JG
- Coggeshall J
- Cogneras E
- Cojocaru CD
- Colas J
- Colijn AP
- Collaboration ATLAS
- Collard C
- Collins NJ
- Collins-Tooth C
- Collot J
- Colon G
- Coniavitis E
- Conidi MC
- Consonni M
- Consorti V
- Constantinescu S
- Conta C
- Conventi F
- Cook J
- Cooke M
- Cooper BD
- Cooper-Sarkar AM
- Copic K
- Cornelissen T
- Corradi M
- Correia AMH
- Corriveau F
- Corso-Radu A
- Cortes-Gonzalez A
- Cortiana G
- Costa G
- Costa MJ
- Costanzo D
- Costin T
- Cote D
- Courneyea L
- Cowan G
- Cowden C
- Cox BE
- Cranmer K
- Cranshaw J
- Crepe-Renaudin S
- Crescioli F
- Cristinziani M
- Crosetti G
- Crupi R
- Cuciuc C-M
- Curatolo M
- Curtis CJ
- Curull XE
- Cwetanski P
- Czirr H
- Czyczula Z
- D'Auria S
- D'Onofrio M
- D'Orazio A
- Da Costa JBG
- Da Costa JGPF
- Da Silva PVM
- Da Via C
- Dabrowski W
- Dai T
- Dallapiccola C
- Daly CH
- Dam M
- Damazio DO
- Dameri M
- Damiani DS
- Danielsson HO
- Dannheim D
- Dao V
- Darbo G
- Darlea GL
- Daum C
- Dauvergne JP
- Davey W
- Davidek T
- Davidson N
- Davidson R
- Davies E
- Davies M
- Davison AR
- Davygora Y
- Dawe E
- Dawson I
- Dawson JW
- Daya-Ishmukhametova RK
- de Asmundis R
- De Castro S
- De Cecco S
- De Graat J
- De Groot N
- De Jong P
- De la Hoz SG
- De la Taille C
- De la Torre H
- De Lima JGR
- De Lotto B
- De Mora L
- De Nooij L
- De Pedis D
- De Regie JBDV
- De Renstrom PAB
- De Salvo A
- De Sanctis U
- De Santo A
- De K
- Dean S
- Debbe R
- Dedovich DV
- Degenhardt J
- Dehchar M
- Del Papa C
- Del Peso J
- Del Prete T
- Deliyergiyev M
- Dell'Acqua A
- Dell'Asta L
- Della Pietra M
- Della Porta GZ
- della Volpe D
- Delmastro M
- Delpierre P
- Delruelle N
- Delsart PA
- Deluca C
- Demers S
- Demichev M
- Demirkoz B
- Deng J
- Deng W
- Denis RDS
- Denisov SP
- Derendarz D
- Derkaoui JE
- Derue F
- Dervan P
- Desch K
- Devetak E
- Deviveiros PO
- Dewhurst A
- DeWilde B
- Dhaliwal S
- Dhullipudi R
- Di Ciaccio A
- Di Ciaccio L
- Di Girolamo A
- Di Girolamo B
- Di Luise S
- Di Mattia A
- Di Micco B
- Di Nardo R
- Di Simone A
- Di Sipio R
- Diaz MA
- Diblen F
- Diehl EB
- Dietrich J
- Dietzscha TA
- Diglio S
- Dingfelder J
- Dionisi C
- Dita P
- Dita S
- Dittus F
- Djama F
- Djobava T
- do Vale MAB
- Do ValleWemans A
- Doan TKO
- Dobbs M
- Dobinson R
- Dobos D
- Dobson E
- Dobson M
- Dodd J
- Doglioni C
- Doherty T
- Dohmae T
- Doi Y
- Dolejsi J
- Dolenc I
- Dolezal Z
- Dolgoshein BA
- Donadelli M
- Donega M
- Donini J
- Donszelmann TC
- Dopke J
- Doria A
- Dos Anjos A
- Dos Santos DR
- Dosil M
- Dotti A
- Dova MT
- Dowell JD
- Doxiadis AD
- Doyle AT
- Drasal Z
- Drees J
- Dressnandt N
- Drevermann H
- Driouichi C
- Dris M
- Dubbert J
- Dubbs T
- Dube S
- Duchovni E
- Duckeck G
- Dudarev A
- Dudziak F
- Duehrssen M
- Duerdoth IP
- Dueren M
- Duflot L
- Dufour M-A
- Dunford M
- Duxfield R
- Dwuznik M
- Dydak F
- Ebenstein WL
- Ebke J
- Eckert S
- Eckweiler S
- Edmonds K
- Edwards CA
- Edwards NC
- Ehrenfeld W
- Ehrich T
- Eifert T
- Eigen G
- Einsweiler K
- Eisenhandler E
- Ekelof T
- El Kacimi M
- El Moursli RC
- Ellert M
- Elles S
- Ellinghaus F
- Ellis K
- Ellis N
- Elmsheuser J
- Elsing M
- Emeliyanov D
- Engelmann R
- Engl A
- Epp B
- Eppig A
- Erdmann J
- Ereditato A
- Eriksson D
- Ernst J
- Ernst M
- Ernwein J
- Errede D
- Errede S
- Ertel E
- Escalier M
- Eschrich IG
- Escobar C
- Esposito B
- Etienne F
- Etienvre AI
- Etzion E
- Evangelakou D
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- Yilmaz M
- Yoosootiniya R
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- Zhemchugov A
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- Zieminska D
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- Zinonos Z
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- Zitoun R
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- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of âs = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pTâ„20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60â€pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2â€{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Ackers M
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogan T
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Alam MS
- Albrand S
- Aleksa M
- Aleksandrov IN
- Aleppo M
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso J
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Andari N
- Andeen T
- Anders CF
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angerami A
- Anghinolfi F
- Anh TV
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Observation of associated near-side and away-side long-range correlations in âsNN=5.02ââTeV proton-lead collisions with the ATLAS detector
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdel Khalek S
- Abdelalim AA
- Abdinov O
- Aben R
- Abi B
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- Acharya BS
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- Ahlen SP
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- Alam MA
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- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
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- Alexandre G
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- Aliev M
- Alimonti G
- Alison J
- Allbrooke BM
- Allison LJ
- Allport PP
- Allwood-Spiers SE
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- Yamanaka T
- Yamauchi K
- Yamazaki T
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- Yang UK
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- Yanush S
- Yao L
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- Yen AL
- Yilmaz M
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- Yorita K
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- Yoshihara K
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- Young CJ
- Youssef S
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- Yu J
- Yuan L
- Yurkewicz A
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- Zaidan R
- Zaitsev AM
- Zambito S
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zenin O
- ZeniĆĄ T
- Zerwas D
- Zevi Della Porta G
- Zhang D
- Zhang H
- Zhang J
- Zhang L
- Zhang X
- Zhang Z
- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- ZivkoviÄ L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- American Physical Society
- Publication date
- 01/01/2012
- Field of study
Two-particle correlations in relative azimuthal angle (ÎÏ) and pseudorapidity (Îη) are measured in âsNN=5.02ââTeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1ââÎŒb-1 of data as a function of transverse momentum (pT) and the transverse energy (ÎŁETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Îη|<5) ânear-sideâ (ÎÏâŒ0) correlation that grows rapidly with increasing ÎŁETPb. A long-range âaway-sideâ (ÎÏâŒÏ) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ÎŁETPb, is found to match the near-side correlation in magnitude, shape (in Îη and ÎÏ) and ÎŁETPb dependence. The resultant ÎÏ correlation is approximately symmetric about Ï/2, and is consistent with a dominant cosâĄ2ÎÏ modulation for all ÎŁETPb ranges and particle pT
Measurement of the cross-section of high transverse momentum vector bosons reconstructed as single jets and studies of jet substructure in pp collisions at âs = 7 TeV with the ATLAS detector
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdinov O
- Aben R
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Abulaitia Y
- Acharya BS
- Adamczyk L
- Adams DL
- Addy TN
- Adelman J
- Adomeit S
- Adye T
- Agatonovic-Jovin T
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- Budagov IA
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- Burmeister I
- Busato E
- Bussey P
- Bustos ACF
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- Butler B
- Butler JM
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- Butterworth JM
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- Calderini G
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- Castelli A
- Castillo Gimenez V
- Castillo IS
- Castillo LRF
- Castillo LRF
- Castro NF
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- Chelkov GA
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- Chen Y
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- Chernyatin V
- Cheu E
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- Chiarella V
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- Chromek-Burckhart D
- Chu ML
- Chudoba J
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- Cortes-Gonzalez A
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- Da Costa JGPF
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- Da Cunha Sargedas De Sousa MJ
- Da Via C
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- Dafinca A
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- Dale O
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- De Castro S
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- De la Torre H
- de Lima DEF
- de Lima DEF
- De Lorenzi F
- De Mendizabal JB
- De Nooij L
- De Pedis D
- De Regie JBDV
- de Renstrom PAB
- De Salvo A
- De Sanctis U
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- Dechenaux B
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- Degenhardt J
- Deigaard I
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- Del Prete T
- Delemontex T
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- Dell'Acqua A
- Dell'Asta L
- Della Pietra M
- della Porta GZ
- della Volpe D
- Delmastro M
- Delsart PA
- Deluca C
- Demers S
- Demichev M
- Demilly A
- Demirkoz B
- Denisov SP
- Derendarz D
- Derkaoui JE
- Derue F
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- Deviveiros PO
- Dewhurst A
- Dhaliwal S
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- Di Domenico A
- Di Donato C
- Di Girolamo A
- Di Girolamo B
- Di Mattia A
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- Di Simone A
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- Djama F
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- do Vale MAB
- Doan TKO
- Dobos D
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- Doglioni C
- Doherty T
- Dohmae T
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- Dueren M
- Duflot L
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- Dwuznik M
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- Edson W
- Edwards NC
- Ehrenfeld W
- Eifert T
- Eigen G
- Einsweiler K
- Ekelof T
- El Kacimi M
- El Moursli A
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- Ellert M
- Elles S
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- Emeliyanov D
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- Enari Y
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- Endner OC
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- Endo M
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- Engelmann R
- Engelmann R
- Erdmann J
- Erdmann J
- Ereditato A
- Ereditato A
- Eriksson D
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- Ernis G
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- Ernst J
- Ernst J
- Ernst M
- Ernst M
- Ernwein J
- Ernwein J
- Errede D
- Errede D
- Errede S
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- Ertel E
- Ertel E
- Escalier M
- Escalier M
- Esch H
- Esch H
- Escobar C
- Escobar C
- Espinal Curull X
- Espinal Curull X
- Esposito B
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- Etienne F
- Etienne F
- Etienvre AI
- Etienvre AI
- Etzion E
- Etzion E
- Evans H
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- Fabbri L
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- Facini G
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- Fakhrutdinov RM
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- Faltova J
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- Farooque T
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- Farrell S
- Farrell S
- Farrington SM
- Farrington SM
- Farthouat P
- Farthouat P
- Fassi F
- Fassi F
- Fassnacht P
- Fassnacht P
- Fassouliotis D
- Fassouliotis D
- Favareto A
- Favareto A
- Fayard L
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- Federic P
- Federic P
- Fedin OL
- Fedin OL
- Fedorko W
- Fedorko W
- Fehling-Kaschek M
- Fehling-Kaschek M
- Feigl S
- Feigl S
- Feligioni L
- Feligioni L
- Feng C
- Feng C
- Feng EJ
- Feng EJ
- Feng H
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- Fenyuk AB
- Fenyuk AB
- Fernando W
- Fernando W
- Ferrag S
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- Ferrando BMS
- Ferrando J
- Ferrando J
- Ferrara V
- Ferrara V
- Ferrari A
- Ferrari A
- Ferrari P
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- Ferrari R
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- Ferrer A
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- Ferrere D
- Ferrere D
- Ferretti C
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- Fiascaris M
- Fiascaris M
- Fiedler F
- Fiedler F
- Filipcic A
- Filipcic A
- Filipuzzi M
- Filipuzzi M
- Filthaut F
- Filthaut F
- Fincke-Keeler M
- Fincke-Keeler M
- Finelli KD
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- Fiolhais MCN
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- Fiorini L
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- Firan A
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- Fischer J
- Fischer J
- Fisher MJ
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- Fitzgerald EA
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- Flechl M
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- Fleck I
- Fleck I
- Fleischmann P
- Fleischmann P
- Fleischmann S
- Fleischmann S
- Fletcher G
- Fletcher G
- Fletcher GT
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- Flick T
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- Floderus A
- Floderus A
- Florez Bustos AC
- Flowerdew MJ
- Flowerdew MJ
- Formica A
- Formica A
- Forti A
- Forti A
- Fortin D
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- Fournier D
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- Fox H
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- Francavilla P
- Francavilla P
- Franchini M
- Franchini M
- Franchino S
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- Francis D
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- Franklin M
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- Franz S
- Franz S
- Fraternali M
- Fraternali M
- Fratin S
- Fratina S
- French ST
- French ST
- Friedrich C
- Friedrich C
- Friedrich F
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- Froidevaux D
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- Frost JA
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- Fukunaga C
- Fukunaga C
- Fulsom BG
- Fulsom BG
- Fuster J
- Fuster J
- Gabaldon C
- Gabaldon C
- Gabizon O
- Gabizon O
- Gabrielli A
- Gabrielli A
- Gabrielli A
- Gabrielli A
- Gadatsch S
- Gadatsch S
- Gadomski S
- Gadomski S
- Gagliardi G
- Gagliardi G
- Gagnon P
- Gagnon P
- Galea C
- Galea C
- Galhardo B
- Galhardo B
- Gallas EJ
- Gallas EJ
- Gallo V
- Gallo V
- Gallop BJ
- Gallop BJ
- Gallus P
- Gallus P
- Galster G
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- Gan KK
- Gan KK
- Gandrajula RP
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- Gao J
- Gao YS
- Gao YS
- Gaob J
- Garberson F
- Garberson F
- Garcia Navarro JE
- Garcia Navarro JE
- Garcia BRM
- Garcia C
- Garcia C
- Garcia JAB
- Garcia-Sciveres M
- Garcia-Sciveres M
- Gardner RW
- Gardner RW
- Garelli N
- Garelli N
- Garonne V
- Garonne V
- Garrido MDMC
- Gatti C
- Gatti C
- Gaudio G
- Gaudio G
- Gaur B
- Gaur B
- Gauthier L
- Gauthier L
- Gauzzi P
- Gauzzi P
- Gavrilenko IL
- Gavrilenko IL
- Gay C
- Gay C
- Gaycken G
- Gaycken G
- Gazis EN
- Gazis EN
- Ge P
- Ge P
- Gecse Z
- Gecse Z
- Gee CNP
- Gee CNP
- Geerts DAA
- Geerts DAA
- Geich-Gimbel C
- Geich-Gimbel C
- Gellerstedt K
- Gellerstedt K
- Gemme C
- Gemme C
- Gemmell A
- Gemmell A
- Genest MH
- Genest MH
- Gentile S
- Gentile S
- George M
- George M
- George S
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- Gerbaudo D
- Gerbaudo D
- Gershon A
- Gershon A
- Ghazlane H
- Ghazlane H
- Ghodbane N
- Ghodbane N
- Giacobbe B
- Giacobbe B
- Giagu S
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- Giangiobbe V
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- Giannetti P
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- Gianotti F
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- Gibbard B
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- Gibson SM
- Gibson SM
- Gilchriese M
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- Gillam TPS
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- Gillberg D
- Gillberg D
- Gillman AR
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- Gingrich DM
- Gingrich M
- Giokaris N
- Giokaris N
- Giordani MP
- Giordani MP
- Giordano R
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- Giorgi FM
- Giorgi FM
- Giraud PF
- Giraud PF
- Giugni D
- Giugni D
- Giuliani C
- Giuliani C
- Giunta M
- Giunta M
- Gjelsten BK
- Gjelsten BK
- Gkialas I
- Gkialas I
- Gladilin LK
- Gladilin LK
- Glasman C
- Glasman C
- Glatzer J
- Glatzer J
- Glazov A
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- Goddard JR
- Goddard JR
- Godfrey J
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- Goeringer C
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- Goessling C
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- Gonalo R
- Goncalo R
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- Gonzalez Parra G
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- Gonzalez-Sevilla S
- Goossens L
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- Gorbounov PA
- Gorbounov PA
- Gordon HA
- Gordon HA
- Gorelov I
- Gorelov I
- Gorini B
- Gorini B
- Gorini E
- Gorini E
- Gorisek A
- Gorisek A
- Gornicki E
- Gornicki E
- Goshaw AT
- Goshaw AT
- Gostkin MI
- Gostkin MI
- Gouighri M
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- Goujdami D
- Goujdami D
- Goulette MP
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- Goussiou AG
- Goussiou AG
- Goy C
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- Gozpinar S
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- Grabas HMX
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- Graber L
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- Grafstroem P
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- Gramling J
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- Grancagnolo S
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- Grassi V
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- Gratchev V
- Gratchev V
- Gray HM
- Gray HM
- Graziani E
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- Grebenyuk OG
- Grebenyuk OG
- Greenwood ZD
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- Gregor IM
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- Griffiths J
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- Grillo AA
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- Griso SP
- Grivaz J-F
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- Grohs JP
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2014
- Field of study
This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to all-hadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of âs = 7 TeV;{\rm Te}{\rm V}andcorrespondtoanintegratedluminosityof4.6\;{\rm f}{{{\rm b}}^{-1}}.ThemeasurementisperformedbyreconstructingtheboostedWorZbosonsinsinglejets.ThereconstructedjetmassisusedtoidentifytheWandZbosons,andajetsubstructuremethodbasedonenergyclusterinformationinthejetcentreâofâmassframeisusedtosuppressthelargemultiâjetbackground.ThecrossâsectionforeventswithahadronicallydecayingWorZboson,withtransversemomentum{{p}_{{\rm T}}}\gt 320\;{\rm Ge}{\rm V}andpseudorapidity|\eta |\lt 1.9,ismeasuredtobe{{\sigma }_{W+Z}}=8.5\pm 1.7$ pb and is compared to next-to-leading-order calculations. The selected events are further used to study jet grooming techniques
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