1,558 research outputs found
Air/water interfacial waves with a droplet at the tip of their crest
In nature, it is common to observe water wave crests with a droplet at their tip. This fascinating configuration remains unexplained from the physical point of view. The present study explores such a unique local configuration numerically. Solitary waves that propagate at the interface between two layers of irrotational fluids are considered. Extending the work of Guan et al. [âA local model for the limiting configuration of interfacial solitary waves,â J. Fluid Mech. 921, A9 (2021)], the density ratio has been decreased to a very small value equal to 0.001, which is close to the air/water density ratio at sea level (0.0013). A highly accurate solution for the limiting configuration of solitary waves is obtained by solving the irrotational Euler equations using the boundary integral method and Newton's iterations. It is confirmed that the limiting configuration consisting of a droplet sitting on a crest with a [Formula: see text] angle exists for very small density ratios. This limiting configuration obviously does not exist for surface waves with a void on the top, thus stressing the crucial role played by the air. The droplet is stationary in a frame of reference moving with the wave and experiences intense shear at its tip. From the energy point of view, the formation of a crest with a droplet is accompanied by a remarkable drop of kinetic and potential energies of water in the vicinity of the crest. Furthermore, we present a simple set of scaling relations for the fall of the droplet
New and simple algorithms for stable flow problems
Stable flows generalize the well-known concept of stable matchings to markets
in which transactions may involve several agents, forwarding flow from one to
another. An instance of the problem consists of a capacitated directed network,
in which vertices express their preferences over their incident edges. A
network flow is stable if there is no group of vertices that all could benefit
from rerouting the flow along a walk.
Fleiner established that a stable flow always exists by reducing it to the
stable allocation problem. We present an augmenting-path algorithm for
computing a stable flow, the first algorithm that achieves polynomial running
time for this problem without using stable allocation as a black-box
subroutine. We further consider the problem of finding a stable flow such that
the flow value on every edge is within a given interval. For this problem, we
present an elegant graph transformation and based on this, we devise a simple
and fast algorithm, which also can be used to find a solution to the stable
marriage problem with forced and forbidden edges.
Finally, we study the stable multicommodity flow model introduced by
Kir\'{a}ly and Pap. The original model is highly involved and allows for
commodity-dependent preference lists at the vertices and commodity-specific
edge capacities. We present several graph-based reductions that show
equivalence to a significantly simpler model. We further show that it is
NP-complete to decide whether an integral solution exists
Hidden Conformal Symmetry of Extremal Kerr-Bolt Spacetimes
We show that extremal Kerr-Bolt spacetimes have a hidden conformal symmetry.
In this regard, we consider the wave equation of a massless scalar field
propagating in extremal Kerr-Bolt spacetimes and find in the "near region", the
wave equation in extremal limit can be written in terms of the
quadratic Casimir. Moreover, we obtain the microscopic entropy of the extremal
Kerr-Bolt spacetimes also we calculate the correlation function of a
near-region scalar field and find perfect agreement with the dual 2D CFT.Comment: 13 page
Kerr/CFT, dipole theories and nonrelativistic CFTs
We study solutions of type IIB supergravity which are SL(2,R) x SU(2) x
U(1)^2 invariant deformations of AdS_3 x S^3 x K3 and take the form of products
of self-dual spacelike warped AdS_3 and a deformed three-sphere. One of these
backgrounds has been recently argued to be relevant for a derivation of
Kerr/CFT from string theory, whereas the remaining ones are holographic duals
of two-dimensional dipole theories and their S-duals. We show that each of
these backgrounds is holographically dual to a deformation of the DLCQ of the
D1-D5 CFT by a specific supersymmetric (1,2) operator, which we write down
explicitly in terms of twist operators at the free orbifold point. The
deforming operator is argued to be exactly marginal with respect to the
zero-dimensional nonrelativistic conformal (or Schroedinger) group - which is
simply SL(2,R)_L x U(1)_R. Moreover, in the supergravity limit of large N and
strong coupling, no other single-trace operators are turned on. We thus propose
that the field theory duals to the backgrounds of interest are nonrelativistic
CFTs defined by adding the single Schroedinger-invariant (1,2) operator
mentioned above to the original CFT action. Our analysis indicates that the
rotating extremal black holes we study are best thought of as finite
right-moving temperature (non-supersymmetric) states in the above-defined
supersymmetric nonrelativistic CFT and hints towards a more general connection
between Kerr/CFT and two-dimensional non-relativistic CFTs.Comment: 48+8 pages, 4 figures; minor corrections and references adde
Estimation of the solubility parameters of model plant surfaces and agrochemicals: a valuable tool for understanding plant surface interactions
Background
Most aerial plant parts are covered with a hydrophobic lipid-rich cuticle, which is the interface between the plant organs and the surrounding environment. Plant surfaces may have a high degree of hydrophobicity because of the combined effects of surface chemistry and roughness. The physical and chemical complexity of the plant cuticle limits the development of models that explain its internal structure and interactions with surface-applied agrochemicals. In this article we introduce a thermodynamic method for estimating the solubilities of model plant surface constituents and relating them to the effects of agrochemicals.
Results
Following the van Krevelen and Hoftyzer method, we calculated the solubility parameters of three model plant species and eight compounds that differ in hydrophobicity and polarity. In addition, intact tissues were examined by scanning electron microscopy and the surface free energy, polarity, solubility parameter and work of adhesion of each were calculated from contact angle measurements of three liquids with different polarities. By comparing the affinities between plant surface constituents and agrochemicals derived from (a) theoretical calculations and (b) contact angle measurements we were able to distinguish the physical effect of surface roughness from the effect of the chemical nature of the epicuticular waxes. A solubility parameter model for plant surfaces is proposed on the basis of an increasing gradient from the cuticular surface towards the underlying cell wall.
Conclusions
The procedure enabled us to predict the interactions among agrochemicals, plant surfaces, and cuticular and cell wall components, and promises to be a useful tool for improving our understanding of biological surface interactions
The Guinea-Bissau Family of Mycobacterium tuberculosis Complex Revisited
The Guinea-Bissau family of strains is a unique group of the Mycobacterium tuberculosis complex that, although genotypically closely related, phenotypically demonstrates considerable heterogeneity. We have investigated 414 M. tuberculosis complex strains collected in Guinea-Bissau between 1989 and 2008 in order to further characterize the Guinea-Bissau family of strains. To determine the strain lineages present in the study sample, binary outcomes of spoligotyping were compared with spoligotypes existing in the international database SITVIT2. The major circulating M. tuberculosis clades ranked in the following order: AFRI (nâ=â195, 47.10%), Latin-American-Mediterranean (LAM) (nâ=â75, 18.12%), ill-defined T clade (nâ=â53, 12.8%), Haarlem (nâ=â37, 8.85%), East-African-Indian (EAI) (nâ=â25, 6.04%), Unknown (nâ=â12, 2.87%), Beijing (nâ=â7, 1.68%), X clade (nâ=â4, 0.96%), Manu (nâ=â4, 0.97%), CAS (nâ=â2, 0.48%). Two strains of the LAM clade isolated in 2007 belonged to the Cameroon family (SIT61). All AFRI isolates except one belonged to the Guinea-Bissau family, i.e. they have an AFRI_1 spoligotype pattern, they have a distinct RFLP pattern with low numbers of IS6110 insertions, and they lack the regions of difference RD7, RD8, RD9 and RD10, RD701 and RD702. This profile classifies the Guinea-Bissau family, irrespective of phenotypic biovar, as part of the M. africanum West African 2 lineage, or the AFRI_1 sublineage according to the spoligtyping nomenclature. Guinea-Bissau family strains display a variation of biochemical traits classically used to differentiate M. tuberculosis from M. bovis. Yet, the differential expression of these biochemical traits was not related to any genes so far investigated (narGHJI and pncA). Guinea-Bissau has the highest prevalence of M. africanum recorded in the African continent, and the Guinea-Bissau family shows a high phylogeographical specificity for Western Africa, with Guinea-Bissau being the epicenter. Trends over time however indicate that this family of strains is waning in most parts of Western Africa, including Guinea-Bissau (pâ=â0.048)
pTcGW plasmid vectors 1.1 version: a versatile tool for Trypanosoma cruzi gene characterisation
The effects of using the PReDicT Test to guide the antidepressant treatment of depressed patients: study protocol for a randomised controlled trial
Background
Antidepressant medication is commonly used to treat depression. However, many patients do not respond to the first medication prescribed and improvements in symptoms are generally only detectable by clinicians 4â6 weeks after the medication has been initiated. As a result, there is often a long delay between the decision to initiate an antidepressant medication and the identification of an effective treatment regimen.
Previous work has demonstrated that antidepressant medications alter subtle measures of affective cognition in depressed patients, such as the appraisal of facial expression. Furthermore, these cognitive effects of antidepressants are apparent early in the course of treatment and can also predict later clinical response. This trial will assess whether an electronic test of affective cognition and symptoms (the Predicting Response to Depression Treatment Test; PReDicT Test) can be used to guide antidepressant treatment in depressed patients and, therefore, hasten treatment response compared to a control group of patients treated as usual.
Methods/design
The study is a randomised, two-arm, multi-centre, open-label, clinical investigation of a medical device, the PReDicT Test. It will be conducted in five European countries (UK, France, Spain, Germany and the Netherlands) in depressed patients who are commencing antidepressant medication. Patients will be randomised to treatment guided by the PReDicT Test (PReDicT arm) or to Treatment as Usual (TaU arm). Patients in the TaU arm will be treated as per current standard guidelines in their particular country. Patients in the PReDicT arm will complete the PReDicT Test after 1 (and if necessary, 2) weeks of treatment. If the test indicates non-response to the treatment, physicians will be advised to immediately alter the patientâs antidepressant therapy by dose escalation or switching to another compound. The primary outcome of the study is the proportion of patients showing a clinical response (defined as 50% or greater decrease in baseline scores of depression measured using the Quick Inventory of Depressive Symptoms â Self-Rated questionnaire) at week 8. Health economic and acceptability data will also be collected and analysed.
Discussion
This trial will test the clinical efficacy, cost-effectiveness and acceptability of using the novel PReDicT Test to guide antidepressant treatment selection in depressed patients
X-ray emission from the Sombrero galaxy: discrete sources
We present a study of discrete X-ray sources in and around the
bulge-dominated, massive Sa galaxy, Sombrero (M104), based on new and archival
Chandra observations with a total exposure of ~200 ks. With a detection limit
of L_X = 1E37 erg/s and a field of view covering a galactocentric radius of ~30
kpc (11.5 arcminute), 383 sources are detected. Cross-correlation with Spitler
et al.'s catalogue of Sombrero globular clusters (GCs) identified from HST/ACS
observations reveals 41 X-rays sources in GCs, presumably low-mass X-ray
binaries (LMXBs). We quantify the differential luminosity functions (LFs) for
both the detected GC and field LMXBs, whose power-low indices (~1.1 for the
GC-LF and ~1.6 for field-LF) are consistent with previous studies for
elliptical galaxies. With precise sky positions of the GCs without a detected
X-ray source, we further quantify, through a fluctuation analysis, the GC LF at
fainter luminosities down to 1E35 erg/s. The derived index rules out a
faint-end slope flatter than 1.1 at a 2 sigma significance, contrary to recent
findings in several elliptical galaxies and the bulge of M31. On the other
hand, the 2-6 keV unresolved emission places a tight constraint on the field
LF, implying a flattened index of ~1.0 below 1E37 erg/s. We also detect 101
sources in the halo of Sombrero. The presence of these sources cannot be
interpreted as galactic LMXBs whose spatial distribution empirically follows
the starlight. Their number is also higher than the expected number of cosmic
AGNs (52+/-11 [1 sigma]) whose surface density is constrained by deep X-ray
surveys. We suggest that either the cosmic X-ray background is unusually high
in the direction of Sombrero, or a distinct population of X-ray sources is
present in the halo of Sombrero.Comment: 11 figures, 5 tables, ApJ in pres
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
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