A micromachined freestanding terahertz absorber with an array of metallic patches

An array of square metallic patches on a thin suspended dielectric layer is introduced as an effective terahertz absorber. The suspended structure is placed on a metalized substrate and the device exhibits metamaterial behavior at specific frequencies determined by the size of the patches. It is feasible to place patches with different sizes in an array formation for a broadband absorber. In array configuration, individual elements induce distinct resonances yielding narrow band absorption regions. Design of the absorber is described using electromagnetic simulations. The absorber structure was fabricated on a silicon wafer using standard microfabrication techniques. The characteristics of the absorber were measured using a terahertz time domain spectroscope. The measured data match well the simulations indicating strong absorption peaks in a band of 0.5-2 THz

Vancomycın resıstant enterococcus bacteremıa ın a patıent wıth Pneumocystis jiroveci pneumonıa, granulocystıc sarcoma and acute respıratory dıstress syndrome

In this case report we aimed to present a patient with granulocytic sarcomaa, neutropenic fever, ARDS and Pneumocystis jirovecii pneumoniae that was hospitalized in our intensive care unit. The patient recovered and  then developed vancomycin resistant enterococci (VRE) bacteremia due to port catheter during follow up. The patient had risk factors for VRE bacteremia and he was administered linezolide without removing the catheter. He was discharged with recovery.Key words: Granulocystic sarcoma, Pneumocystis jiroveci pneumoniae, vancomycin resistant enterococci, (VRE

First records of anomalously white harbour porpoises (Phocoena phocoena) in the Turkish seas with a global review

Dede, Ayhan/0000-0002-7712-615X; YESILCICEK, TUNCAY/0000-0002-3236-8227; Tonay, Arda M./0000-0003-2718-9328; Kose, Ozay/0000-0002-3565-160XWOS: 000320413100012Three anomalously white harbour porpoises (Phocoena phocoena) were reported in Turkish Seas. One of them was bycaught on 19 June 2011 in bottom gill nets off the eastern coast of the Turkish Black Sea. the second one was observed four times in May and early June 2012 in the Istanbul Strait. the last one was stranded alive on 7 July 2012 in the Istanbul Strait. Records (published and unpublished) of anomalously white harbour porpoises in the world were reviewed. in total, 34 records were found from the world seas: the Black Sea, North Sea, Baltic Sea, North Atlantic Ocean and North Eastern Pacific Ocean. According to these records, three patterns of pigmentation were suggested.Recep Tayym Erdogan UniversityRecep Tayyip Erdogan University [BAP 2010.103 03 2]; Istanbul UniversityIstanbul University [BAP 184761, BAP 27942]The authors thank S. Berrow, O K. Didockson, K. Flannery, PG H Evans, A. Gob, Z. Gunelidze, I Hasselmeier, L Hutchings, W Keener, C.C. Kinze, L Morison, S. Pezeril, D. Quigley, K Robinson, D. Schulte, R Sears, A. U for observation data and old photos, A. Beird for photos, A.E. Kutukcu for video in Istanbul Strait, E. Danyer and I Aytemiz for necropsy report, H Bayar for necropsy assistance, 13 Topaloglu for photos of case 3 and logistic, S. Akmermer, K Akmermer and U. Akmermer for help in Size, L Eadie, T de Haas, N. Tonay and Kirecburnu's fishermen in Istanbul, Coast Guard for cooperation in IU/TUDAV Cetacean Stranding Network; V. Onar and P.S C. Turetken for help in fixation case 3, P Korkmazel, K. Guzey/ANIMA for colour grading and video time warping, B. Ozturk, P Gol'din and D Fertl for their valuable advises; A A Ozturk, R. Bilgin, C. Torso for their contributions during editing Case I study was supported by Recep Tayym Erdogan University, Scientific Research Project (BAP 2010.103 03 2). Case 2 study was supported by Istanbul University, Scientific Research Pealed (BAP 184761 Case 3 preserving and exhibit was provided by Istanbul University, Scientific Research Project (BAP 27942

The Advocate - June 8, 1961

Original title (1951-1987)--The Advocate: official publication of the Archdiocese of Newark (N.J.)

Vancomycin versus Linezolid in the Treatment of Methicillin-Resistant Staphylococcus aureus Meningitis

Abstract Background: Vancomycin is the mainstay of treatment for methicillin-resistant Staphylococcus aureus (MRSA) meningitis. However, successful outcomes with linezolid have not been reported in a large series of patients. We conducted a single-center retrospective cohort study to compare vancomycin with linezolid in the treatment of MRSA meningitis. Methods: We extracted data and outcomes for all adult patients (age > 18 years) with culture-proved MRSA meningitis who received vancomycin or linezolid between January 2006 and June 2011. A definite diagnosis of meningitis was based on the isolation of MRSA in at least one cerebrospinal fluid (CSF) culture and findings in CSF that are typical of the infection. Linezolid was given intravenously (IV) at a dosage of 600 mg q12h and vancomycin IV at 500 mg q6h. Results: A total of 8 patients with MRSA meningitis (5 male, 3 female; age [mean -SD] 61.6 -13.2 years) received vancomycin and 9 patients (7 male, 2 female; age 59.1 -15.6 years) received linezolid. All isolated strains of MRSA were susceptible to both vancomycin and linezolid. The rates of microbiologic success with linezolid or vancomycin, in terms of clearance of MRSA from CSF on day 5, were 7/9 and 2/8 (p = 0.044, Fisher exact test). No severe adverse events occurred in either treatment arm of the study. One-month survival of the patients in whom treatment was successful microbiologically was 2/2 in the vancomycin-treated group and 4/7 in the linezolidtreated group. Minimum inhibitory concentration (MIC) data for vancomycin were available for 5/6 treatment failures with vancomycin, and vancomycin MIC values of these five strains were 2 mg/L. Conclusion: Analysis of the findings in the limited cohorts in our study suggests that linezolid is superior to vancomycin for treating MRSA meningitis, especially in cases in which there is a high MIC (2 mg/L) for vancomycin. A clinical study involving larger cohorts may increase the evidence available in relation to this question

Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins

Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other classes, such as neurotoxins (e.g., anatoxin-a) and cytotoxins (e.g., cylindrospermopsin) due to their potency. Most studies examine the relationship between individual toxin variants and environmental factors, such as nutrients, temperature and light. In summer 2015, we collected samples across Europe to investigate the effect of nutrient and temperature gradients on the variability of toxin production at a continental scale. Direct and indirect effects of temperature were the main drivers of the spatial distribution in the toxins produced by the cyanobacterial community, the toxin concentrations and toxin quota. Generalized linear models showed that a Toxin Diversity Index (TDI) increased with latitude, while it decreased with water stability. Increases in TDI were explained through a significant increase in toxin variants such as MC-YR, anatoxin and cylindrospermopsin, accompanied by a decreasing presence of MC-LR. While global warming continues, the direct and indirect effects of increased lake temperatures will drive changes in the distribution of cyanobacterial toxins in Europe, potentially promoting selection of a few highly toxic species or strains.Peer reviewe

Koagülaz negatif stafilokoklarda "slime" faktörünün, araştırılması ve antibiyotik duyarlılıklarının belirlenmesi

Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.ÖZET Son yıllarda KNS'lar tarafından "slime" üretiminin artan virülansm bir göstergesi olarak kullanılabileceği düşüncesi in-vitro teknikle "slime" üretimi ve aderans çalışmalarını gündeme getirmiştir. Bu çalışmada Ege Üniversitesi Tıp Fakültesi Mikrobiyoloji Laboratuvarma Mart 1996 - Nisan 1997 tarihleri arasında yollanan intravenöz kateterlerden soyutlanan 29, DAPD sıvılarında 14 ve BOS şantı bulunan olgulardan soyutlanan 7 KNS kökeni incelendi. Kontrol grubu olarak hastane personeli dışındaki bireylerden rastlantısal olarak alınan deri sürüntülerinden soyutlanan 50 KNS kökeni kullanıldı. Çalışma ve kontrol grubundaki olgular "slime" varlığı açısından hem kalitatif hem kantitatif olarak değerlendirildi ve antibiyotik duyarlılıkları araştırıldı. Çalışma grubundaki 50 KNS kökeninin 30'unda (%60), kontrol grubundaki 50 KNS kökeninin 8'sında (%12) "slime" varlığı saptandı. Bu fark istatistiksel olarak da anlamlı bulundu. "Slime": varlığı hem tüp yöntemiyle hem de spektrofotometrik yöntemle incelendiğinde, her iki yöntem sonuçlarının paralellik gösterdiği saptandı. Çalışma ve kontrol grubunda tüm KNS kökenleri vankomisin ve teikoplanine duyarlı bulundu. "Slime" oluşumu ile antibiyotik direnç oranları ve MİK değerleri arasında istatistiksel olarak anlamlı fark saptanmadı. Birçok çalışma "slime" üretiminin enfeksiyonla ilişkili bir gösterge olduğunu ve "slime" üreten KNS kökenlerinin, "slime" üretmeyenlere göre daha zor eradike edilebildiğini göstermiştir. Bu açıdan enfeksiyon etkeni olan KNS'lerin "slime" üretme yeteneği hakkında bilgi sahibi olmak klinisyenlere sağaltım yaklaşımını belirlemede yardımcı olacaktır. 37 l'l>, l'mc^r.;,. ili S /; » ti,.;

Ahlakın biyolojik açıklamaları ve altruizmin felsefi bir analizi

The main purpose of my thesis is to show that morality is not unique to humans and it does not separate humans from nature. To that end I first discuss the issue of emotions to emphasize that biological accounts are more significant than cultural ones. Then, I focus on the notion of altruism that I find central to morality. In this part, I examine different approaches to altruism and try to reveal that the emotion of empathy is the main motivation behind altruistic behavior. I touch upon the mechanisms underlying empathy and defend a multilayered structure for empathy. Also by appealing to evidence of altruistic behavior in other animal species, I present that there is a continuity of morality between humans and other animals. The phenomenon of morality is about how we get in touch with our environment. Here, the environment is the other individuals with which we interrelatedly constitute a social structure. This structure provides us a less distressed life time compared to a solitary lifestyle. The way such a social structure works is not coincidental or arbitrary. It relies on the emotions that motivate social and moral behavior, and they are the result of a long evolutionary history. Accordingly, the concept of altruism seems to be the most pivotal element of morality because the structure can continue to exist only in an interrelated manner, and this interrelation requires altruistic characteristics. .Thesis (M.S.) -- Graduate School of Social Sciences. Philosophy