3,118 research outputs found

    Ambiente virtual de aprendizaje como herramienta didáctica para el aprendizaje de la robótica educativa en estudiantes del grado décimo del I.C.S desde un enfoque holístico transformador

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    Con base en la problemática que presentaban los estudiantes del grado décimo del Instituto Colombo Sueco I.C.S localidad 1 Bogotá, relacionada con el área de tecnología e informática, específicamente con la temática de robótica educativa, se diseñó e implementó un Ambiente Virtual de Aprendizaje con el fin de mejorar significativamente el proceso de enseñanza aprendizaje en la construcción de robots teleoperadores enfocados en los insectoides. El A.V.A estuvo orientado por el Modelo Pedagógico Holístico Transformador del Dr. Giovanni Iafrancesco Villegas a través de la plataforma Moodle, cuyo contenido es un software libre que permite la creación de módulos estructurados con actividades específicas esenciales en el diseño de ambientes virtuales. La investigación benefició a los estudiantes de los niveles básica y media y educadores-mediadores que enseñaron la temática de robótica educativa ya que ampliaron sus conocimientos frente al tema, tuvieron a su disposición el (AVA) diseñado específicamente para tal fin, que además cumplió el propósito de ser un instrumento para gestionar procesos de enseñanza aprendizaj

    Ambiente virtual de aprendizaje como herramienta didáctica para el aprendizaje de la robótica educativa en estudiantes del grado décimo del I.C.S desde un enfoque holístico transformador

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    Con base en la problemática que presentaban los estudiantes del grado décimo del Instituto Colombo Sueco I.C.S localidad 1 Bogotá, relacionada con el área de tecnología e informática, específicamente con la temática de robótica educativa, se diseñó e implementó un Ambiente Virtual de Aprendizaje con el fin de mejorar significativamente el proceso de enseñanza aprendizaje en la construcción de robots teleoperadores enfocados en los insectoides. El A.V.A estuvo orientado por el Modelo Pedagógico Holístico Transformador del Dr. Giovanni Iafrancesco Villegas a través de la plataforma Moodle, cuyo contenido es un software libre que permite la creación de módulos estructurados con actividades específicas esenciales en el diseño de ambientes virtuales. La investigación benefició a los estudiantes de los niveles básica y media y educadores-mediadores que enseñaron la temática de robótica educativa ya que ampliaron sus conocimientos frente al tema, tuvieron a su disposición el (AVA) diseñado específicamente para tal fin, que además cumplió el propósito de ser un instrumento para gestionar procesos de enseñanza aprendizaj

    Importance of university teacher behaviour in the faculty of health science

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    BackgroundWe describe the results from the questionnaire of Tuncel concerning the behaviour of university teachers, since university students believe they have influenced their academic achievement.AimsThe objective of this study was to reveal which behaviours of university teachers were most appreciated by the students in the first year of the studies taught at the Faculty of Health Sciences of Universidad Rey Juan Carlos in Madrid (Degrees in Medicine, Nursing, Physiotherapy, Dentistry, Psychology and Occupational Therapy).Methods 540 first-year students from the Health Sciences degree participated. An exploratory factor analysis of the items was performed and the internal consistency was studied using Cronbach’s alpha.ResultsStudents placed the most importance on the following areas: “Emotional aptitude of the university teacher”, “University teacher-student interaction”, “Achievement of teaching objectives”, “Connection between the teaching of theory and practical components”, “Organization and planning of teaching” and “Correct students and providing them with information on their progress and evolution”. It should be noted that affective factors and the relationship and close interaction with students were the areas most demanded and valued by the students.ConclusionMaking the teaching process more effective is an important goal of educational research. But few researchers take into account the point of view of the students and are primarily involved in determining the behaviour of university teachers. Therefore our aim in this study was to find out their opinions. We wanted to know which attitudes are the most valued by students of the Rey Juan Carlos University (Madrid, Spain) studying for degrees in the health sciences program. Once identified, we will be able to use this information to identify teaching strategies that could improve the minimum academic requirements of the university

    Trends in primary total hip arthroplasty in Spain from 2001 to 2008: Evaluating changes in demographics, comorbidity, incidence rates, length of stay, costs and mortality

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    <p>Abstract</p> <p>Background</p> <p>Hip arthroplasties is one of the most frequent surgical procedures in Spain and are conducted mainly in elderly subjects. We aim to analyze changes in incidence, co-morbidity profile, length of hospital stay (LOHS), costs and in-hospital mortality (IHM) of patients undergoing primary total hip arthroplasty (THA) over an 8-year study period in Spain.</p> <p>Methods</p> <p>We selected all surgical admissions in individuals aged ≥40 years who had received a primary THA (ICD-9-CM procedure code 81.51) between 2001 and 2008 from the National Hospital Discharge Database. Age- and sex-specific incidence rates, LOHS, costs and IHM were estimated for each year. Co-morbidity was assessed using the Charlson comorbidity index.</p> <p>Multivariate analysis of time trends was conducted using Poisson regression. Logistic regression models were conducted to analyze IHM.</p> <p>Results</p> <p>We identified a total of 161,791 discharges of patients having undergone THA from 2001 to 2008. Overall crude incidence had increased from 99 to 105 THA per 100.000 inhabitants from 2001 to 2008 (p < 0.001). In 2001, 81% of patients had a Charlson Index of 0, 18.4% of 1-2, and 0.6% > 2 and in 2008, the prevalence of 1-2 or >2 had increased to 20.4% and 1.1% respectively (p < 0.001). The mean LOHS was 13 days in 2001 and decreased to 10.45 days in 2008 (p < 0.001). During the period studied, the mean cost per patient increased from 6,634 to 9,474 Euros. Multivariate analysis shows that from 2001 to 2008 the incidence of THA hospitalizations has significantly increased for both sexes and only men showed a significant reduction in IHM after THA.</p> <p>Conclusions</p> <p>The current study provides clear and valid data indicating increased incidence of primary THA in Spain from 2001 to 2008 with concomitant reductions in LOHS, slight reduction IHM, but a significant increase in cost per patient. The health profile of the patient undergoing a THA seems to be worsening in Spain.</p

    Application of FMEA as support in the preventive maintenance of the pneumatic machine norbar

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    This paper aims to identify the use of the Failure Mode and Effect Analysis (FMEA) tool as a support for the preventive maintenance of the Pneutorque Norbar machine, as well as in the strategic maintenance planning applied. A bibliographic study was carried out to contextualize the subject, followed by a case study. The research demonstrates how the development of an equipment failure analysis process, identifying the results obtained through the FMEA tool with the Statistical Process Control (CEP). For this, we analyzed this method in the process of maintenance and support of the Pneutorque Norbar machine, intending to obtain satisfactory results in the improvement of the maintenance planning process

    Comportamientos del profesor universitario y éxito académico de los estudiantes de los grados de maestro de infantil y primaria

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     It´s disturbing to think about the idea that the teacher can lead a student to achieve great successes or, on the contrary, beat him academically. It´s for this reason that it´s necessary to explore the behavior of teaching professionals, from the point of view of the student, to know which ones they consider that will impact positively on their academic success. In order to this, a sample of 486 pupils from grades Primary Education Teachers (199) and Primary (287) in the Faculty of Education of Albacete (University of Castilla La Mancha) Education was analized. A questionnaire (Tuncel, 2009) (from few questions and the type of response ) was applied and, using a Factor Analysis Exploratory, there were found six dimensions to which the students gave the highest importance: "Emotional aptitude of teachers " ; " Teacher-student interaction " ; " Achieving the goals of education" , "Connecting between teaching of theory and practices " ; "Planning and organization of teaching " ; "Correct and provide information to students about their advance and progress." Es inquietante la idea de pensar que el profesor puede conseguir que un alumno alcance grandes éxitos o que, por el contrario se hunda académicamente.Es por ello por lo que se hace necesario explorar los comportamientos de los profesionales de la enseñanza en la Educación superior, desde el punto de vista del alumno, para conocer cuáles son los que ellos consideran que repercutirán de forma positiva en su éxito académico.Para ello se contó con una muestra de 486 alumnos, pertenecientes a los grados de Maestros de Educación Infantil (199) y Educación Primaria (287) en la Facultad de Educación de Albacete (Universidad de Castilla la Mancha).Se aplicó  un cuestionario (Tuncel, 2009)  y mediante un Análisis Factorial exploratorio, aparecieron seis dimensiones a las cuales los alumnos le otorgaron la mayor importancia, siendo estas: “Aptitud emocional de los profesores”; “Interacción profesor-alumno”; “Lograr y conseguir los objetivos de la enseñanza”, “Conexión durante la instrucción de la teoría con las practicas”; “Planificación y organización  de la docencia”; “Corregir y proporcionar informaciones a los alumnos de sus avances y progresos”

    La vid silvestre en México. Actualidades y potencial

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    En ocho capítulos se aborda el estado del arte de la vid silvestre en MéxicoEl estudio de las especies vegetales nativas de México representa un reto que cada día más investigadores mexicanos asumen. Durante muchos años, el apoyo a la investigación pública ha sido mínimo; desde el punto de vista agronómico es insuficiente para avanzar a la velocidad que requiere nuestro país para afrontar problemas de producción y distribución de alimentos. Por esa razón, entre otras, me es grato presentar esta obra que compila parte de los trabajos de la Red de Vid Silvestre patrocinada por el Sistema Nacional de Recursos Fitogenéticos (sinarefi) dependiente de la sagarpa; trabajos apuntalados por investigadores que sin pertenecer a la red han colaborado en el estudio de las plantas del género Vitis. En este libro se muestra el potencial del país para aprovechar el recurso vid, empleado desde antes de la conquista española por nativos mexicanos que conocían sus bondades. Es necesario continuar el avance en el conocimiento de este recurso, por ello el presente libro pretende invitar a toda persona interesada en contribuir con el rescate y conservación de las vides mexicanas. Los autores y editores, así como las instituciones en donde laboramos y aquellas que patrocinan estas investigaciones, esperamos se cumpla este objetivo y que el lector, alumno, profesor, investigador, público en general, disfrute esta lectura y, sobre todo, se interese en el recurso VitisSEP, SINAREFI, UAEME

    Host adaptive immunity deficiency in severe pandemic influenza

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    INTRODUCTION: Pandemic A/H1N1/2009 influenza causes severe lower respiratory complications in rare cases. The association between host immune responses and clinical outcome in severe cases is unknown. METHODS: We utilized gene expression, cytokine profiles and generation of antibody responses following hospitalization in 19 critically ill patients with primary pandemic A/H1N1/2009 influenza pneumonia for identifying host immune responses associated with clinical outcome. Ingenuity pathway analysis 8.5 (IPA) (Ingenuity Systems, Redwood City, CA) was used to select, annotate and visualize genes by function and pathway (gene ontology). IPA analysis identified those canonical pathways differentially expressed (P < 0.05) between comparison groups. Hierarchical clustering of those genes differentially expressed between groups by IPA analysis was performed using BRB-Array Tools v.3.8.1. RESULTS: The majority of patients were characterized by the presence of comorbidities and the absence of immunosuppressive conditions. pH1N1 specific antibody production was observed around day 9 from disease onset and defined an early period of innate immune response and a late period of adaptive immune response to the virus. The most severe patients (n = 12) showed persistence of viral secretion. Seven of the most severe patients died. During the late phase, the most severe patient group had impaired expression of a number of genes participating in adaptive immune responses when compared to less severe patients. These genes were involved in antigen presentation, B-cell development, T-helper cell differentiation, CD28, granzyme B signaling, apoptosis and protein ubiquitination. Patients with the poorest outcomes were characterized by proinflammatory hypercytokinemia, along with elevated levels of immunosuppressory cytokines (interleukin (IL)-10 and IL-1ra) in serum. CONCLUSIONS: Our findings suggest an impaired development of adaptive immunity in the most severe cases of pandemic influenza, leading to an unremitting cycle of viral replication and innate cytokine-chemokine release. Interruption of this deleterious cycle may improve disease outcome.The study was scientifically sponsored by the Spanish Society for Critical Care Medicine (SEMICYUC). Funding: MICCIN-FIS/JCYL-IECSCYL-SACYL (Spain): Programa de Investigación Comisionada en Gripe, GR09/0021-EMER07/050- PI081236-RD07/0067. CIHR-NIH-Sardinia Recherché-LKSF Canada support DJK.S

    Spanish cohort of VEXAS syndrome : clinical manifestations, outcome of treatments and novel evidences about UBA1 mosaicism

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    The vacuoles, E1-enzyme, X linked, autoinflammatory and somatic (VEXAS) syndrome is an adult-onset autoinflammatory disease (AID) due to postzygotic UBA1 variants. To investigate the presence of VEXAS syndrome among patients with adult-onset undiagnosed AID. Additional studies evaluated the mosaicism distribution and the circulating cytokines. Gene analyses were performed by both Sanger and amplicon-based deep sequencing. Patients' data were collected from their medical charts. Cytokines were quantified by Luminex. Genetic analyses of enrolled patients (n=42) identified 30 patients carrying UBA1 pathogenic variants, with frequencies compatible for postzygotic variants. All patients were male individuals who presented with a late-onset disease (mean 67.5 years; median 67.0 years) characterised by cutaneous lesions (90%), fever (66.7%), pulmonary manifestations (66.7%) and arthritis (53.3%). Macrocytic anaemia and increased erythrocyte sedimentation rate and ferritin were the most relevant analytical abnormalities. Glucocorticoids ameliorated the inflammatory manifestations, but most patients became glucocorticoid-dependent. Positive responses were obtained when targeting the haematopoietic component of the disease with either decitabine or allogeneic haematopoietic stem cell transplantation. Additional analyses detected the UBA1 variants in both haematopoietic and non-haematopoietic tissues. Finally, analysis of circulating cytokines did not identify inflammatory mediators of the disease. Thirty patients with adult-onset AID were definitively diagnosed with VEXAS syndrome through genetic analyses. Despite minor interindividual differences, their main characteristics were in concordance with previous reports. We detected for the first time the UBA1 mosaicism in non-haematopoietic tissue, which questions the previous concept of myeloid-restricted mosaicism and may have conceptual consequences for the disease mechanisms

    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

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    BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
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