Construction, validation and, visualization of a web-based nomogram to identify the best candidates for primary tumor resection in advanced cutaneous melanoma patients

BackgroundExisting studies have shown whether primary site resection (PSR) in cutaneous melanoma (CM) patients with stage IV is controversial. Our study aimed to identify the clinical characteristics of CM patients with stage IV who benefited from PSR on a population-based study.MethodsWe retrospectively reviewed stage IV CM patients in the Surveillance, Epidemiology, and End Results (SEER) database from 2004 to 2015. Patients were divided into surgical and non-surgical groups according to whether PSR was performed or not. According to the median cancer-specific survival (CSS) time of the non-surgery group, the surgical group was divided into the surgery-benefit group and the non-surgery-benefit group. Multivariate cox regression analysis was used to explore independent CSS prognostic factors in the surgical group. Then, based on the independent prognostic factors of the surgical group, we established a web-based nomogram based on logistics regression.ResultsA total of 574 stage IV CM patients were included in our study, and 491 (85.60%) patients were included in the surgical group. The clinical characteristics (benefit group and non-benefit group) included age, M stage, lesion location, and ulceration status. These independent prognostic factors were includeed to construct a web-based nomogram.ConclusionsWe constructed a web-based nomogram. This model was suitable for identifying the best candidates suitable for PSR in stage IV CM patients

Measurement of the tt̄W and tt̄Z production cross sections in pp collisions at √s = 8 TeV with the ATLAS detector

The production cross sections of top-quark pairs in association with massive vector bosons have been measured using data from pp collisions at s√ = 8 TeV. The dataset corresponds to an integrated luminosity of 20.3 fb−¹ collected by the ATLAS detector in 2012 at the LHC. Final states with two, three or four leptons are considered. A fit to the data considering the tt̄W and tt̄Z processes simultaneously yields a significance of 5.0σ (4.2σ) over the background-only hypothesis for tt¯Wtt¯W (tt̄Z) production. The measured cross sections are σtt̄W = 369 + 100−91 fb and σtt̄Z = 176 + 58−52 fb. The background-only hypothesis with neither tt̄W nor tt̄Z production is excluded at 7.1σ. All measurements are consistent with next-to-leading-order calculations for the tt̄W and tt̄Z processes

Measurement of the photon identification efficiencies with the ATLAS detector using LHC Run-1 data

© 2016, CERN for the benefit of the ATLAS collaboration.The algorithms used by the ATLAS Collaboration to reconstruct and identify prompt photons are described. Measurements of the photon identification efficiencies are reported, using 4.9 fb- 1 of pp collision data collected at the LHC at s=7 TeV and 20.3 fb- 1 at s=8 TeV. The efficiencies are measured separately for converted and unconverted photons, in four different pseudorapidity regions, for transverse momenta between 10 GeV and 1.5 TeV. The results from the combination of three data-driven techniques are compared to the predictions from a simulation of the detector response, after correcting the electromagnetic shower momenta in the simulation for the average differences observed with respect to data. Data-to-simulation efficiency ratios used as correction factors in physics measurements are determined to account for the small residual efficiency differences. These factors are measured with uncertainties between 0.5% and 10% in 7 TeV data and between 0.5% and 5.6% in 8 TeV data, depending on the photon transverse momentum and pseudorapidity

Search for squarks and gluinos in final states with jets and missing transverse momentum at root s=13 TeV with the ATLAS detector

SCOAP

Charged-particle distributions in pp interactions at √s = 8 TeV measured with the ATLAS detector

This paper presents measurements of distributions of charged particles which are produced in proton– proton collisions at a centre-of-mass energy of √s = 8 TeV and recorded by the ATLAS detector at the LHC. A special dataset recorded in 2012 with a small number of interactions per beam crossing (below 0.004) and corresponding to an integrated luminosity of 160 µb−1 was used. A minimumbias trigger was utilised to select a data sample of more than 9 million collision events. The multiplicity, pseudorapidity, and transverse momentum distributions of charged particles are shown in different regions of kinematics and chargedparticle multiplicity, including measurements of final states at high multiplicity. The results are corrected for detector effects and are compared to the predictions of various Monte Carlo event generator models which simulate the full hadronic final state

Analysis on the Difference of Reconstructed Soil Moisture Content in a Grassland Open-Pit Mining Area of China

To reveal the variability of different reconstructed soil ratios and different vegetation growth grades on the water holding capacity of recon-structed soil, the most suitable ratio of reconstructed soil materials was explored. Taking the inner dump of Shengli mining area in Inner Mongolia of China as the research area, the reconstructed soil of reclaimed land was investigated and sampled. One-way analysis of variance was used to analyze the difference of the moisture content of the reconstructed soil, and the reasons for the difference were discussed. The results showed that: (1) Among the different soil reconstructions, soil moisture content was higher when soil reconstructions were rock and soil stripping material: coal gangue: fly ash = 3:4:3. The soil moisture content of un-reclaimed land was mostly at a high level when the soil reconstruction method was rock and soil stripping material; and the soil moisture content was not at the highest level when the vegetation growth grade was higher. This indicates that it was not the case that the better the vegetation growth condition was, the higher the soil moisture content was. (2) In the case where the soil reconstruction method was rock and soil stripping material: coal gangue = 2:3, the soil moisture content of the reclaimed land decreased with the reduction of tillage frequency when the vegetation growth condition was optimal (vegetation growth grade was 4). (3) In the case where the soil reconstruction method was rock and soil stripping material: coal gangue: fly ash = 3:4:3, when the vegetation growth condition was better (vegetation growth grade was 3 and 4), the soil moisture content of the re-claimed land was highest when it was tilled once every 15 days. It was also found in combination with other soil reconstruction methods that it was not always the case that the higher the frequency of tillage, the higher the soil moisture content. The study of coal gangue, fly ash and rocky soil stripping as topsoil substitute materials with their different ratios on reconstructed soil provides support for the reclamation work in topsoil scarce mines and provides technical reference for the ecological restoration project of grassland open-pit mines in the same climate zone

Analysis on the Difference of Reconstructed Soil Moisture Content in a Grassland Open-Pit Mining Area of China

To reveal the variability of different reconstructed soil ratios and different vegetation growth grades on the water holding capacity of recon-structed soil, the most suitable ratio of reconstructed soil materials was explored. Taking the inner dump of Shengli mining area in Inner Mongolia of China as the research area, the reconstructed soil of reclaimed land was investigated and sampled. One-way analysis of variance was used to analyze the difference of the moisture content of the reconstructed soil, and the reasons for the difference were discussed. The results showed that: (1) Among the different soil reconstructions, soil moisture content was higher when soil reconstructions were rock and soil stripping material: coal gangue: fly ash = 3:4:3. The soil moisture content of un-reclaimed land was mostly at a high level when the soil reconstruction method was rock and soil stripping material; and the soil moisture content was not at the highest level when the vegetation growth grade was higher. This indicates that it was not the case that the better the vegetation growth condition was, the higher the soil moisture content was. (2) In the case where the soil reconstruction method was rock and soil stripping material: coal gangue = 2:3, the soil moisture content of the reclaimed land decreased with the reduction of tillage frequency when the vegetation growth condition was optimal (vegetation growth grade was 4). (3) In the case where the soil reconstruction method was rock and soil stripping material: coal gangue: fly ash = 3:4:3, when the vegetation growth condition was better (vegetation growth grade was 3 and 4), the soil moisture content of the re-claimed land was highest when it was tilled once every 15 days. It was also found in combination with other soil reconstruction methods that it was not always the case that the higher the frequency of tillage, the higher the soil moisture content. The study of coal gangue, fly ash and rocky soil stripping as topsoil substitute materials with their different ratios on reconstructed soil provides support for the reclamation work in topsoil scarce mines and provides technical reference for the ecological restoration project of grassland open-pit mines in the same climate zone

Synthesis, Structure, and Photocatalytic Activity of TiO2-Montmorillonite Composites

In the present study, TiO2-montmorillonite (MMT) composites were synthesized hydrothermally under variable conditions, including the TiO2/MMT mass ratio, reaction pH, reaction temperature, and dwelling time. These samples were determined by X-ray photoelectron spectrometry (XPS), ultraviolet–visible spectroscopy% (UV-Vis DRS), electrochemical impedance spectroscopy (EIS), transient photocurrent responses, photoluminescence (PL) spectra, electron paramagnetic resonance (EPR), and N2 adsorption–desorption isotherms. The photocatalytic activity was evaluated as the ability to promote the visible-light-driven degradation of 30 mg/L of aqueous methylene blue, which was maximized for the composite with a TiO2 mass ratio of 30 wt% prepared at a pH of 6, a reaction temperature of 160 °C, and a dwelling time of 24 h (denoted as 30%-TM), which achieved a methylene blue removal efficiency of 95.6%, which was 4.9 times higher than that of pure TiO2. The unit cell volume and crystallite size of 30%-TM were 92.43 Å3 and 9.28 nm, respectively, with a relatively uniform distribution of TiO2 particles on the MMT’s surface. In addition, 30%-TM had a large specific surface area, a strong light absorption capacity, and a high Ti3+ content among the studied catalysts. Thus, the present study provides a basis for the synthesis of composites with controlled structures

Synthesis, Structure, and Photocatalytic Activity of TiO₂-Montmorillonite Composites

In the present study, TiO2-montmorillonite (MMT) composites were synthesized hydrothermally under variable conditions, including the TiO2/MMT mass ratio, reaction pH, reaction temperature, and dwelling time. These samples were determined by X-ray photoelectron spectrometry (XPS), ultraviolet–visible spectroscopy% (UV-Vis DRS), electrochemical impedance spectroscopy (EIS), transient photocurrent responses, photoluminescence (PL) spectra, electron paramagnetic resonance (EPR), and N2 adsorption–desorption isotherms. The photocatalytic activity was evaluated as the ability to promote the visible-light-driven degradation of 30 mg/L of aqueous methylene blue, which was maximized for the composite with a TiO2 mass ratio of 30 wt% prepared at a pH of 6, a reaction temperature of 160 °C, and a dwelling time of 24 h (denoted as 30%-TM), which achieved a methylene blue removal efficiency of 95.6%, which was 4.9 times higher than that of pure TiO2. The unit cell volume and crystallite size of 30%-TM were 92.43 Å3 and 9.28 nm, respectively, with a relatively uniform distribution of TiO2 particles on the MMT’s surface. In addition, 30%-TM had a large specific surface area, a strong light absorption capacity, and a high Ti3+ content among the studied catalysts. Thus, the present study provides a basis for the synthesis of composites with controlled structures