724 research outputs found

    WEB PRESENCE AND STRUCTURE EVALUATION OF THE EUROPEAN NATIONAL LIBRARIES’ WEBSITES: A STUDY

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    The purpose of this study is to evaluate European national libraries’ websites on the basis of webometrics. It also analyze the structure of the selected European national libraries’ websites on the basis of number of checkpoints. On the basis of number of web indicators such as number of webpages, in-links, rich content files, publications in Google Scholar and WISER, web presence of the selected European national libraries’ websites were examined. For collection of webometrics data Google search engine and Check PageRank tool were used. To evaluate structure’s attributes, a checklist was drafted which is based on published literature and guidelines. This paper highlights that most of the European national libraries have sound web presence having large number of webpages, in-links and rich content files. It also reveals that most of the European national libraries’ websites have users’ friendly structure except few national libraries’ websites. Therefore, there is a need to conduct regular observation to find out the utility of website among users’ group

    WEB PRESENCE AND STRUCTURE EVALUATION OF THE EUROPEAN NATIONAL LIBRARIES’ WEBSITES: A STUDY

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    The purpose of this study is to evaluate European national libraries’ websites on the basis of webometrics. It also analyze the structure of the selected European national libraries’ websites on the basis of number of checkpoints. On the basis of number of web indicators such as number of webpages, in-links, rich content files, publications in Google Scholar and WISER, web presence of the selected European national libraries’ websites were examined. For collection of webometrics data Google search engine and Check PageRank tool were used. To evaluate structure’s attributes, a checklist was drafted which is based on published literature and guidelines. This paper highlights that most of the European national libraries have sound web presence having large number of webpages, in-links and rich content files. It also reveals that most of the European national libraries’ websites have users’ friendly structure except few national libraries’ websites. Therefore, there is a need to conduct regular observation to find out the utility of website among users’ group

    Gastrin-Releasing Peptide and Glucose Metabolism Following Pancreatitis

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    Background Gastrin-releasing peptide (GRP) is a pluripotent peptide that has been implicated in both gastrointestinal inflammatory states and classical chronic metabolic diseases such as diabetes. Abnormal glucose metabolism (AGM) after pancreatitis, an exemplar inflammatory disease involving the gastrointestinal tract, is associated with persistent low-grade inflammation and altered secretion of pancreatic and gut hormones as well as cytokines. While GRP is involved in secretion of many of them, it is not known whether GRP has a role in AGM. Therefore, we aimed to investigate the association between GRP and AGM following pancreatitis. Methods Fasting blood samples were collected to measure GRP, blood glucose, insulin, amylin, glucagon, pancreatic polypeptide (PP), somatostatin, cholecystokinin, gastric-inhibitory peptide (GIP), gastrin, ghrelin, glicentin, glucagon-like peptide-1 and 2, oxyntomodulin, peptide YY (PYY), secretin, vasoactive intestinal peptide, tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein (MCP)-1, and interleukin-6. Modified Poisson regression analysis and linear regression analyses were conducted. Four statistical models were used to adjust for demographic, metabolic, and pancreatitis-related risk factors. Results A total of 83 individuals after an episode of pancreatitis were recruited. GRP was significantly associated with AGM, consistently in all four models (P -trend < 0.05), and fasting blood glucose contributed 17% to the variance of GRP. Further, GRP was significantly associated with glucagon (P < 0.003), MCP-1 (P < 0.025), and TNF-α (P < 0.025) - consistently in all four models. GRP was also significantly associated with PP and PYY in three models (P < 0.030 for both), and with GIP and glicentin in one model (P = 0.001 and 0.024, respectively). Associations between GRP and other pancreatic and gut hormones were not significant. Conclusion GRP is significantly increased in patients with AGM after pancreatitis and is associated with increased levels of pro-inflammatory cytokines, as well as certain pancreatic and gut hormones. Detailed mechanistic studies are now warranted to investigate the exact role of GRP in derangements of glucose homeostasis following pancreatitis

    Cytogenetic analysis of two species of genus Protosticta from Himachal Pradesh, India

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    367-369Cytogenetically, out of 262 species, only three species of family Platystictidae has been reported worldwide. Present study has been undertaken to study chromosome complement and its characterization of more species of this family. Cytogenetic analyses of Protosticta sanguinostigma Fraser, 1992 and Protosticta uncata Fraser, 1931 of family Platystictidae, collected from Andretta, Himachal Pradesh, India have been carried out on the basis of conventional staining, C-banding and silver nitrate staining. Both the species possess n=13m as haploid chromosome number and X0-XX sex determining mechanism. One large bivalent is present in all the meiotic stages of P. sanguinostigma which is considered as the species specific character. Chromosome complement of both the species shows variation in distribution of C-bands and Nucleolar organizer regions (NORs). Cytologically, both the species have been described for the first time

    U-Pb single grain zircon ages for Sanbagawa Metamorphic Rocks in central Shikoku (Japan): the Sanbagawa Belt re-united

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    The high-P/low-T Sanbagawa Metamorphic Belt that traverses SW Japan, has been subdivided into two belts thought to have been metamorphosed at ca. 120 Ma and at ca. 65 Ma (‘Sanbagawa Metamorphic Rocks’ and ‘Shimanto Metamorphic Rocks’). The subdivision was based on the assumption that metamorphism occurred at ca. 116 Ma, largely based on an early Rb-Sr isotope study and zircon data obtained for the eclogite unit of the Sanbagawa Belt, whereas in some parts of the belt detrital zircons of late Cretaceous age (90-80 Ma) were discovered. Analysis of detrital zircons sampled from two sites within the area considered to expose the older ‘Sanbagawa Metamorphic Rocks’, including the area investigated by the Rb-Sr study, reveals the presence of zircons younger than 95 Ma in all samples and some grains as young as 80 ± 4 Ma. It is therefore concluded that the Sanbagawa Belt is one single tectonic entity that formed in the Late Cretaceous though it contains older components, including fossiliferous clasts, older basic meta-volcanics and eclogite units that may record earlier metamorphic events

    COVID-19 Disrupted Provision and Utilization of Health and Nutrition Services in Uttar Pradesh, India: Insights From Service Providers, Household Phone Surveys, and Administrative Data

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    BACKGROUND: The coronavirus (COVID-19) pandemic may substantially affect health systems, but little primary evidence is available on disruption of health and nutrition services. OBJECTIVES: This study aimed to 1) determine the extent of disruption in provision and utilization of health and nutrition services induced by the pandemic in Uttar Pradesh, India; and 2) identify how adaptations were made to restore service provision in response to the pandemic. METHODS: We conducted longitudinal surveys with frontline workers (FLWs, n = 313) and mothers of children \u3c 2 y old (n = 659) in December 2019 (in-person) and July 2020 (by phone). We also interviewed block-level managers and obtained administrative data. We examined changes in service provision and utilization using Wilcoxon matched-pairs signed-rank tests. RESULTS: Compared with prepandemic, service provision reduced substantially during lockdown (83-98 percentage points, pp), except for home visits and take-home rations (∼ 30%). Most FLWs (68%-90%) restored service provision in July 2020, except for immunization and hot cooked meals (\u3c 10%). Administrative data showed similar patterns of disruption and restoration. FLW fears, increased workload, inadequate personal protective equipment (PPE), and manpower shortages challenged service provision. Key adaptations made to provide services were delivering services to beneficiary homes (∼ 40%-90%), social distancing (80%), and using PPE (40%-50%) and telephones for communication (∼ 20%). On the demand side, service utilization reduced substantially (40-80 pp) during the lockdown, but about half of mothers received home visits and food supplementation. Utilization for most services did not improve after the lockdown, bearing the challenges of limited travel (30%), nonavailability of services (26%), and fear of catching the virus when leaving the house (22%) or meeting service providers (14%). CONCLUSIONS: COVID-19 disrupted the provision and use of health and nutrition services in Uttar Pradesh, India, despite adaptations to restore services. Strengthening logistical support, capacity enhancement, performance management, and demand creation are needed to improve service provision and utilization during and post-COVID-19

    Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

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    Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

    Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

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    A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV
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