Mathematical modeling of thermal stabilization of vertical wells on high performance computing systems

Temperature stabilization of oil and gas wells is used to ensure stability and prevent deformation of a subgrade estuary zone. In this work, we consider the numerical simulation of thermal stabilization using vertical seasonal freezing columns. A mathematical model of such problems is described by a time-dependent temperature equation with phase transitions from water to ice. The resulting equation is a standard nonlinear parabolic equation. Numerical implementation is based on the finite element method using the package Fenics. After standard purely implicit approximation in time and simple linearization, we obtain a system of linear algebraic equations. Because the size of freezing columns are substantially less than the size of the modeled area, we obtain mesh refinement near columns. Due to this, we get a large system of equations which are solved using high performance computing systems.Comment: 9 pages, 5 figure

Aligning the CMS Muon Chambers with the Muon Alignment System during an Extended Cosmic Ray Run

Peer reviewe

Measurement of the inclusive W± and Z/γ* cross sections in the e and μ decay channels in pp collisions at √s=7 TeV with the ATLAS detector

The production cross sections of the inclusive Drell-Yan processes W-+/- -> l nu and Z/gamma* -> ll (l = e, mu) are measured in proton-proton collisions at root s = 7 TeV with the ATLAS detector. The cross sections are reported integrated over a fiducial kinematic range, extrapolated to the full range, and also evaluated differentially as a function of the W decay lepton pseudorapidity and the Z boson rapidity, respectively. Based on an integrated luminosity of about 35 pb(-1) collected in 2010, the precision of these measurements reaches a few percent. The integrated and the differential W-+/- and Z/gamma* cross sections in the e and mu channels are combined, and compared with perturbative QCD calculations, based on a number of different parton distribution sets available at next-to-next-to-leading order

New Biocides Based on <i>N</i>⁴-Alkylcytidines: Effects on Microorganisms and Application for the Protection of Cultural Heritage Objects of Painting

The rapid increase in the antibiotic resistance of microorganisms, capable of causing diseases in humans as destroying cultural heritage sites, is a great challenge for modern science. In this regard, it is necessary to develop fundamentally novel and highly active compounds. In this study, a series of N4-alkylcytidines, including 5- and 6-methylcytidine derivatives, with extended alkyl substituents, were obtained in order to develop a new generation of antibacterial and antifungal biocides based on nucleoside derivatives. It has been shown that N4-alkyl 5- or 6-methylcytidines effectively inhibit the growth of molds, isolated from the paintings in the halls of the Ancient Russian Paintings of the State Tretyakov Gallery, Russia, Moscow. The novel compounds showed activity similar to antiseptics commonly used to protect works of art, such as benzalkonium chloride, to which a number of microorganisms have acquired resistance. It was also shown that the activity of N4-alkylcytidines is comparable to that of some antibiotics used in medicine to fight Gram-positive bacteria, including resistant strains of Staphylococcus aureus and Mycobacterium smegmatis. N4-dodecyl-5- and 6-methylcytidines turned out to be the best. This compound seems promising for expanding the palette of antiseptics used in painting, since quite often the destruction of painting materials is caused by joint fungi and bacteria infection

Design of Cx26-H and Cx26-Wt groups.

<p>Note: Cx26-Wt (IVS1+1G>A non-carriers) is shown in blue, Cx26-H (IVS1+1G>A carriers) is shown in red; bilateral arrows show the compared subgroups; ♀ – female, ♂ – male.</p

The correlation of increase of hearing thresholds according to age in individuals with genotype IVS1+1G>A/wt.

<p>Note: Y-axis – hearing thresholds (dB), X-axis – age in years; <i>r_s</i> – the Spearman's rank correlation coefficient, <i>p</i> – statistical significance of Spearman's rank correlation; blue circles – individuals with <i>GJB2</i> genotype wt/wt, red squares – individuals heterozygous for mutation (genotype IVS1+1G>A/wt); blue line shows the absence of hearing thresholds correlation with age in individuals with <i>GJB2</i> genotype wt/wt, red line – the linear regression of increase in hearing thresholds according to age in individuals with <i>GJB2</i> genotype IVS1+1G>A/wt; A – ♀ female, B – ♂ male.</p

Mutation analysis of <i>GJB2</i> gene.

<p>Note: * The frequency of <i>GJB2</i> genotypes was calculated in random sample; in bold are <i>GJB2</i> genotypes selected for comparative analysis of hearing thresholds.</p