203 research outputs found
Cultivating Interdisciplinary Foreign Language Talents in Higher Education in Western China under the Background of the āB&Rā
There is an increasing demand for interdisciplinary foreign language talents who master multiple foreign languages and cultures, innovation ability, and management ability, especially under the āBelt and Roadā background. However, cultivating interdisciplinary foreign language talents in western China is facing many dilemmas. In order to meet the interdisciplinary foreign language talents demand of the international economic development along the āBelt and Roadā, the author puts forward some strategies based on symbiosis theory adopting a comparative method. This article aims to explore methods of cultivating interdisciplinary foreign language talents in higher education in western China and supply high-quality interdisciplinary foreign language talents for the āBelt and Roadā
The ground state entanglement in the model
In this paper, we investigate spin entanglement in the model defined on
a -dimensional bipartite lattice. The concurrence, a measure of the
entanglement between two spins, is analyzed. We prove rigorously that the
ground state concurrence reaches maximum at the isotropic point. For
dimensionality , the concurrence develops a cusp at the isotropic
point and we attribute it to the existence of magnetic long-range order.Comment: 5 pages, 2 figure
Anomalous thermoelectric effects of ZrTe in and beyond the quantum limit
Thermoelectric effects are more sensitive and promising probes to topological
properties of emergent materials, but much less addressed compared to other
physical properties. Zirconium pentatelluride (ZrTe) has inspired active
investigations recently because of its multiple topological nature. We study
the thermoelectric effects of ZrTe in a magnetic field and find several
anomalous behaviors. The Nernst response has a steplike profile near zero field
when the charge carriers are electrons only, suggesting the anomalous Nernst
effect arising from a nontrivial profile of Berry curvature. Both the
thermopower and Nernst signal exhibit exotic peaks in the strong-field quantum
limit. At higher magnetic fields, the Nernst signal has a sign reversal at a
critical field where the thermopower approaches to zero. We propose that these
anomalous behaviors can be attributed to the Landau index inversion, which is
resulted from the competition of the dependence of the Dirac-type
Landau bands and linear- dependence of the Zeeman energy ( is the
magnetic field). Our understanding to the anomalous thermoelectric properties
in ZrTe opens a new avenue for exploring Dirac physics in topological
materials.Comment: 6 pages, 4 figure
DependData: data collection dependability through three-layer decision-making in BSNs for healthcare monitoring
Recently, there have been extensive studies on applying security and privacy protocols in Body Sensor Networks (BSNs) for patient healthcare monitoring (BSN-Health). Though these protocols provide adequate security to data packets, the collected data may still be compromised at the time of acquisition and before aggregation/storage in the severely resource-constrained BSNs. This leads to data collection frameworks being meaningless or undependable, i.e., an undependable BSN-Health. We study data dependability concerns in the BSN-Health and propose a data dependability verification framework named DependData with the objective of verifying data dependability through the decision-making in three layers. The 1st decision-making (1-DM) layer verifies signal-level data at each health sensor of the BSN locally to guarantee that collected signals ready for processing and transmission are dependable so that undependable processing and transmission in the BSN can be avoided. The 2nd decision-making (2-DM) layer verifies data before aggregation at each local aggregator (like clusterhead) of the BSN to guarantee that data received for aggregation is dependable so that undependable data aggregation can be avoided. The 3rd decision-making (3-DM) layer verifies the stored data before the data appears to a remote healthcare data user to guarantee that data available to the owner end (such as smartphone) is dependable so that undependable information viewing can be avoided. Finally, we evaluate the performance of DependData through simulations regarding 1-DM, 2-DM, and 3-DM and show that up to 92% of data dependability concerns can be detected in the three layers. To the best of our knowledge, DependData would be the first framework to address data dependability aside from current substantial studies of security and privacy protocols. We believe the three layers decision-making framework would attract a wide range of applications in the future
Analysis and Prediction of Translation Rate Based on Sequence and Functional Features of the mRNA
Protein concentrations depend not only on the mRNA level, but also on the translation rate and the degradation rate. Prediction of mRNA's translation rate would provide valuable information for in-depth understanding of the translation mechanism and dynamic proteome. In this study, we developed a new computational model to predict the translation rate, featured by (1) integrating various sequence-derived and functional features, (2) applying the maximum relevance & minimum redundancy method and incremental feature selection to select features to optimize the prediction model, and (3) being able to predict the translation rate of RNA into high or low translation rate category. The prediction accuracies under rich and starvation condition were 68.8% and 70.0%, respectively, evaluated by jackknife cross-validation. It was found that the following features were correlated with translation rate: codon usage frequency, some gene ontology enrichment scores, number of RNA binding proteins known to bind its mRNA product, coding sequence length, protein abundance and 5ā²UTR free energy. These findings might provide useful information for understanding the mechanisms of translation and dynamic proteome. Our translation rate prediction model might become a high throughput tool for annotating the translation rate of mRNAs in large-scale
Search for dark matter produced in association with bottom or top quarks in ās = 13 TeV pp collisions with the ATLAS detector
A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fbā1 of protonāproton collision data recorded by the ATLAS experiment at ās = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990ā2021: a systematic analysis for the Global Burden of Disease Study 2021
Background: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, and attributable burden of disease for 88 risk factors in 204 countries and territories and 811 subnational locations, from 1990 to 2021. Methods: The GBD 2021 risk factor analysis used data from 54 561 total distinct sources to produce epidemiological estimates for 88 risk factors and their associated health outcomes for a total of 631 riskāoutcome pairs. Pairs were included on the basis of data-driven determination of a riskāoutcome association. Age-sex-location-year-specific estimates were generated at global, regional, and national levels. Our approach followed the comparative risk assessment framework predicated on a causal web of hierarchically organised, potentially combinative, modifiable risks. Relative risks (RRs) of a given outcome occurring as a function of risk factor exposure were estimated separately for each riskāoutcome pair, and summary exposure values (SEVs), representing risk-weighted exposure prevalence, and theoretical minimum risk exposure levels (TMRELs) were estimated for each risk factor. These estimates were used to calculate the population attributable fraction (PAF; ie, the proportional change in health risk that would occur if exposure to a risk factor were reduced to the TMREL). The product of PAFs and disease burden associated with a given outcome, measured in disability-adjusted life-years (DALYs), yielded measures of attributable burden (ie, the proportion of total disease burden attributable to a particular risk factor or combination of risk factors). Adjustments for mediation were applied to account for relationships involving risk factors that act indirectly on outcomes via intermediate risks. Attributable burden estimates were stratified by Socio-demographic Index (SDI) quintile and presented as counts, age-standardised rates, and rankings. To complement estimates of RR and attributable burden, newly developed burden of proof risk function (BPRF) methods were applied to yield supplementary, conservative interpretations of riskāoutcome associations based on the consistency of underlying evidence, accounting for unexplained heterogeneity between input data from different studies. Estimates reported represent the mean value across 500 draws from the estimate's distribution, with 95% uncertainty intervals (UIs) calculated as the 2Ā·5th and 97Ā·5th percentile values across the draws. Findings: Among the specific risk factors analysed for this study, particulate matter air pollution was the leading contributor to the global disease burden in 2021, contributing 8Ā·0% (95% UI 6Ā·7ā9Ā·4) of total DALYs, followed by high systolic blood pressure (SBP; 7Ā·8% [6Ā·4ā9Ā·2]), smoking (5Ā·7% [4Ā·7ā6Ā·8]), low birthweight and short gestation (5Ā·6% [4Ā·8ā6Ā·3]), and high fasting plasma glucose (FPG; 5Ā·4% [4Ā·8ā6Ā·0]). For younger demographics (ie, those aged 0ā4 years and 5ā14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20Ā·7% [13Ā·9ā27Ā·7]) and environmental and occupational risks (decrease of 22Ā·0% [15Ā·5ā28Ā·8]), coupled with a 49Ā·4% (42Ā·3ā56Ā·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. Age-standardised global DALY rates attributable to high BMI and high FPG rose considerably (15Ā·7% [9Ā·9ā21Ā·7] for high BMI and 7Ā·9% [3Ā·3ā12Ā·9] for high FPG) over this period, with exposure to these risks increasing annually at rates of 1Ā·8% (1Ā·6ā1Ā·9) for high BMI and 1Ā·3% (1Ā·1ā1Ā·5) for high FPG. By contrast, the global risk-attributable burden and exposure to many other risk factors declined, notably for risks such as child growth failure and unsafe water source, with age-standardised attributable DALYs decreasing by 71Ā·5% (64Ā·4ā78Ā·8) for child growth failure and 66Ā·3% (60Ā·2ā72Ā·0) for unsafe water source. We separated risk factors into three groups according to trajectory over time: those with a decreasing attributable burden, due largely to declining risk exposure (eg, diet high in trans-fat and household air pollution) but also to proportionally smaller child and youth populations (eg, child and maternal malnutrition); those for which the burden increased moderately in spite of declining risk exposure, due largely to population ageing (eg, smoking); and those for which the burden increased considerably due to both increasing risk exposure and population ageing (eg, ambient particulate matter air pollution, high BMI, high FPG, and high SBP). Interpretation: Substantial progress has been made in reducing the global disease burden attributable to a range of risk factors, particularly those related to maternal and child health, WaSH, and household air pollution. Maintaining efforts to minimise the impact of these risk factors, especially in low SDI locations, is necessary to sustain progress. Successes in moderating the smoking-related burden by reducing risk exposure highlight the need to advance policies that reduce exposure to other leading risk factors such as ambient particulate matter air pollution and high SBP. Troubling increases in high FPG, high BMI, and other risk factors related to obesity and metabolic syndrome indicate an urgent need to identify and implement interventions
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