8 research outputs found
Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells
- Author
- Adrian Liston
- Alasdair Coles
- Alastair Compston
- An Goris
- Barnaby Fiddes
- Boon
- Bénédicte Dubois
- Carr
- Comabella
- Dendrou
- Di He
- Dooley
- Ellyard
- Eshel
- Field
- Fraussen
- Garcia de Vinuesa
- George Wang
- Gerritse
- Good
- Goris
- Guiducci
- Hauser
- Howard
- Ide Smets
- Jacobson
- James Dooley
- Jellis
- Joanne Jones
- Josselyn E Garcia-Perez
- Jostins
- Kawabe
- Khoury
- Klara Mallants
- Li
- Liu
- Maria Ban
- Maurano
- Montalban
- Moutsianas
- Niino
- Onouchi
- Patsopoulos
- Raj
- Raychaudhuri
- Reichardt
- Sawcer
- Schubert
- Stephanie Humblet-Baron
- Stephen Sawcer
- Summers deLuca
- Tangye
- The Australia and New Zealand Multiple Sclerosis Genetics Consortium
- The International Multiple Sclerosis Genetics Consortium
- The International Multiple Sclerosis Genetics Consortium and The Wellcome Trust Case Control Consortium 2
- Tomer
- Tone
- Vazgiourakis
- Wenjia Liao
- Yanaba
- Yoshizaki
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- Field of study
A robust pipeline with high replication rate for detection of somatic variants in the adaptive immune system as a source of common genetic variation in autoimmune disease
- Author
- Adrian Liston
- Alioto
- Allegretta
- An Goris
- Annemarie Van Nieuwenhuijze
- Battistini
- Beck
- Bénédicte Dubois
- Cai
- Chiu
- Cibulskis
- Dendrou
- Dooley
- Dou
- Forbes
- Genovese
- Haegele
- Hilven
- Ifergan
- Itan
- Jaiswal
- Kelly Hilven
- Kemppinen
- Klara Mallants
- Koboldt
- Koskela
- Labalette
- Li
- Li
- Li
- Lies Van Horebeek
- Lo
- Magerus-Chatinet
- Mass
- McKenna
- Paula Savola
- Plunkett
- Polman
- Rajala
- Sala Frigerio
- Sandmann
- Satu Mustjoki
- Savola
- Souche
- Spencer
- Sriram
- Strioga
- Supek
- Susan M Schlenner
- Tanaka
- The International Multiple Sclerosis Genetics Consortium
- The International Multiple Sclerosis Genetics Consortium and The Wellcome Trust Case Control Consortium 2
- Tiina Kelkka
- Valori
- Vanheusden
- Wang
- Weltevrede
- Xie
- Zink
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- Field of study
The nature of genetic susceptibility to multiple sclerosis: constraining the possibilities
- Author
- A Compston
- AD Sadovnick
- AD Sadovnick
- C Fagnani
- C O’Gorman
- CJ Mumford
- CJ Willer
- DA Dyment
- DA Dyment
- DA Hafler
- DC Clayton
- DM Freedman
- Douglas S. Goodin
- DS Goodin
- DS Goodin
- DS Goodin
- EG Celius
- F Ranzato
- French Research Group on Multiple Sclerosis
- G Ristori
- G Rosati
- GC Ebers
- GC Ebers
- H Kuusisto
- HI Jacobson
- International Multiple Sclerosis Genetics Consortium
- JB Freeman
- JS Witte
- MA Hernán
- MH Barnett
- MH Hofker
- N Koch-Henriksen
- P Bager
- P Khankhanian
- P Sundström
- PL Jager De
- SM Orton
- SV Ramagopalan
- T Hansen
- T Hansen
- T Islam
- T Sarasoja
- The International Multiple Sclerosis Genetics Consortium and the Wellcome Trust Case Control Consortium 2
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Genetic predisposition, humans
- Author
- Acheson
- Aderka
- Agnello
- Ahmed
- AlarcĂłn-Segovia
- Alcina
- American College of Rheumatology Ad Hoc Committee on Systemic Lupus Erythematosus Guidelines
- Amiel
- Amos
- Anderson
- Araki
- Arellano
- Aringer
- Armstrong
- Ascherio
- Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene)
- Axtell
- Axtell
- Baccala
- Baechler
- Bailey
- Bain
- Ban
- Bankovich
- Baranzini
- Barcellos
- Barnes
- Barratt
- Barrett
- Barrett
- Baxter
- Baxter
- Begovich
- Bell
- Bennett
- Bentham
- Bergamaschi
- Bertrams
- Betz
- Blanco-Kelly
- Block
- Blomhoff
- Bonifacio
- Bossingham
- Bottini
- Bowness
- Bradfield
- Brewerton
- Bright
- Broadley
- Cardon
- Carton
- Cayrol
- Cheng
- Christiansen
- Chung
- Compston
- Concannon
- Concannon
- Concannon
- Cooper
- Cooper
- Coraddu
- Cornall
- Cree
- Cross
- Cucca
- Cunninghame Graham
- Cunninghame Graham
- Dausset
- Davies
- Davies
- Davies
- De Jager
- De Jager
- De Jager
- Deapen
- Delépine
- Dendrou
- Denny
- Devendra
- Dietrich
- Dietrich
- Dijstelbloem
- Donner
- Dubois
- Duits
- Ebers
- Ebers
- Ebringer
- Eichhorst
- Ettahar
- Eyre
- Fanciulli
- Field
- Fielder
- Fisher
- Fogdell
- Fogdell-Hahn
- Francis
- Francis
- Franke
- Freedman
- Frisullo
- Frisullo
- Fu
- Fu
- Gaffney
- Gaffney
- Garavito
- Gateva
- Ge
- Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2
- Gerold
- Gonzalez-Escribano
- Gorer
- Graham
- Graham
- Grant
- Gregersen
- Gregory
- Gregory
- Guggenbuhl
- Gyapay
- Haines
- Haines
- Hajeer
- Hakonarson
- Hammarström
- Han
- Harbo
- Hashimoto
- Hatta
- Hawkes
- Healy
- Hinks
- Hirsch
- Hisanaga-Oishi
- Hom
- Hoppenbrouwers
- Hoppenbrouwers
- Horiuchi
- Houssiau
- Howard
- Huang
- Hyttinen
- International Consortium for Systemic Lupus Erythematosus Genetics
- International Genetics of Ankylosing Spondylitis Consortium (IGAS)
- International Multiple Sclerosis Genetics Consortium (IMSGC)
- International Multiple Sclerosis Genetics Consortium (IMSGC)
- International Multiple Sclerosis Genetics Consortium (IMSGC)
- International Multiple Sclerosis Genetics Consortium (IMSGC)
- International Multiple Sclerosis Genetics Consortium (IMSGC)
- International Multiple Sclerosis Genetics Consortium (IMSGC)
- Jacob
- Jacob
- Jacob
- Jacob
- Jersild
- Jersild
- Jin
- Jin
- Johnston
- Jordan
- Jostins
- Julier
- Kachru
- Kallenberg
- Kavvoura
- Kelly
- Kennedy
- Kent
- Khalil
- Khan
- Kim
- Koene
- Kofler
- Kong
- Kool
- Kotsa
- Kouki
- Kozyrev
- Kruglyak
- Kumar
- Kuokkanen
- Kyogoku
- Lander
- Lang
- Langrish
- Lavrikova
- Lawrence
- Lee
- Leikfoss
- Lessard
- Lewis
- Li
- Li
- Li
- Ligers
- Lindqvist
- Lipsker
- Liu
- Liu
- Liu
- Llorente
- Llorente
- Long
- Long
- Lowe
- Luo
- Luo
- Luo
- Luo
- Maier
- Maier
- Malek
- Manzotti
- Marron
- MarroquĂ
- Martin
- Masterman
- Mayes
- McKinney
- Mein
- Mells
- Merriman
- Misu
- Montomoli
- Moore
- Moore
- Morahan
- Mori
- Moriguchi
- Moriguchi
- Moser
- Munger
- Muthian
- Myhr
- Naito
- Nakai
- Nath
- Naves
- Nerup
- Ng
- Nielsen
- Nieves
- Nisticò
- Noble
- Nordmark
- Oaks
- Okada
- Oliveira
- Onengut-Gumuscu
- Onengut-Gumuscu
- Onkamo
- Owerbach
- Panchanathan
- Panitch
- Parkes
- Paterson
- Payne
- Petukhova
- Pociot
- Price
- Provost
- Qian
- Ramagopalan
- Ramagopalan
- Raveney
- Raychaudhuri
- Remmers
- Rieck
- Roberts
- Robertson
- Roychoudhuri
- Rubio
- Rudwaleit
- Sadovnick
- Sadovnick
- Salloum
- Salmon
- Salmon
- Santin
- Sawcer
- Schifferli
- Schlosstein
- Segal
- Seidi
- Shai
- Sigurdsson
- Simpfendorfer
- Smyth
- Smyth
- So
- Soleimanpour
- Soleimanpour
- Stahl
- Steck
- Steck
- Steck
- Stoll
- Strettell
- Sullivan
- Sumaya
- Takaoka
- Tan
- Tavares
- Taylor
- Texido
- Thakker
- The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group
- Thorsby
- Thorsby
- Tillil
- Todd
- Todd
- Todd
- Todd
- Trynka
- Tsang
- Tsao
- Tsoi
- Tsuchiya
- Ueda
- Vafiadis
- Valdes
- Valdes
- van Rood
- Vandenborre
- Vang
- Vazquez
- Velazquez
- Vella
- Vijayakrishnan
- Villar
- Vyse
- Walport
- Walunas
- Wang
- Wang
- Wang
- Wapelhorst
- Weber
- Weiss
- Wellcome Trust Case Control Consortium
- Wiede
- Wilson
- Windhagen
- Wu
- Xi
- Yamada
- Yanagawa
- Yu
- Zheng
- Ziegler
- Zimmerman
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
The translation from genetic knowledge to a molecular understanding of disease is contributing to the development of improved diagnostic and therapeutic products. Here, we briefly cover the localisation of autoimmune disease-associated loci and examine recent progress in molecular understanding of autoimmune disease that has been facilitated by these approaches. We concentrate primarily on progress in the genetics of type 1 diabetes, multiple sclerosis and systemic lupus erythematosus, and draw attention to parallels and contrasts between these diseases, other autoimmune diseases and other immune diseases
Genetic variants are major determinants of CSF antibody levels in multiple sclerosis
- Author
- Achim Berthele
- Allan G. Kermode
- Allanore
- An Goris
- Annette Bang Oturai
- Benjamin Knier
- Berg-Hansen
- Bernhard Hemmer
- Bettina Kullle Andreassen
- Brechtje van Son
- Bruce Taylor
- Buck
- Bénédicte Dubois
- Cepok
- Cepok
- Christian Sindic
- Compston
- Dilthey
- Dobson
- Dorothea Buck
- Elisabeth Gulowsen Celius
- Ferreira
- Filippo Martinelli Boneschi
- Finn Sellebjerg
- Fukazawa
- Giuseppe Liberatore
- Gottenberg
- Gourraud
- Haghighi
- Hanne F. Harbo
- Harbo
- Helle Bach Søndergaard
- Hensiek
- Huss
- Idiman
- Imrell
- Ine Pauwels
- Ingrid Kockum
- Ishii
- Jan Aarseth
- Jan Hillert
- Jeannette Lechner-Scott
- Jennifer PĂ©rez-Boza
- Jersild
- Kelly Hilven
- Kikuchi
- Kjell-Morten Myhr
- Lars Alfredsson
- Lechner-Scott
- Leone
- Link
- Magliozzi
- Manuel Comabella
- Mark Slee
- Marte W. Gustavsen
- Maurizio A. Leone
- Mayringer
- McDonald
- Melissa Sorosina
- Meoli
- Mero
- Nadia Barizzone
- Oak
- Orozco
- Ovsyannikova
- Pandey
- Park
- Pierre-Antoine Gourraud
- Plagnol
- Poser
- Poul Erik H. Jensen
- Purcell
- PĂĄl Berg-Hansen
- Radstake
- Rinker
- Romero-Pinel
- Roxburgh
- Rubicz
- Rudick
- Sahl Khalid Bedri
- Sandra D’Alfonso
- Simon Broadley
- Stangel
- Steffan D. Bos
- Stephen J. Sawcer
- Sundqvist
- Sunny Malhotra
- The International MHC and Autoimmunity Genetics Network
- The International Multiple Sclerosis Genetics Consortium
- The International Multiple Sclerosis Genetics Consortium and The Wellcome Trust Case Control Consortium 2
- Tintore
- Tomas Olsson
- Vincent van Pesch
- Viola Biberacher
- Wu
- Xavier Montalban
- Yoshimura
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- Field of study
Antioxidants for the Prevention and Treatment of Multiple Sclerosis
- Author
- Acar
- Amorini
- Ascherio
- Ascherio
- Bast
- Besler
- Bitsch
- Bjartmar
- Bjelakovic
- Block
- Bonakdar
- Bongarzone
- Bö
- Calabrese
- Cantorna
- Chaturvedi
- Chaudhary
- Compston
- Cooper
- Datta
- De Bustos
- De Groot
- De Luca
- DiMauro
- Dringen
- Dyment
- Ferretti
- Frischer
- GarcĂa-Closas
- Gasperini
- Geromel
- Ghadirian
- Ghafourifar
- Gilgun-Sherki
- Giovannoni
- Graziewicz
- Hadžović-Džuvo
- Haider
- Halliwell
- Halliwell
- Halliwell
- Handel
- Hathcock
- Hemmer
- Hemmer
- HernĂ n
- Hoag
- Holmquist
- Hunter
- IFNB Multiple Sclerosis Group
- International Multiple Sclerosis Genetics Consortium and Wellcome Trust Case Control Consortium 2
- Iwata
- Jacobs
- Jafarirad
- Jiménez-Jiménez
- Johnson
- Khalili
- Kim
- Kurtzke
- Lopes-Diego
- Lovett-Racke
- Lucchinetti
- Lyszczarz
- Løken-Amsrud
- Marracci
- Marrie
- Martinelli Boneschi
- Menge
- Merrill
- Mohebi
- Mora
- Muñoz-Culla
- Myhr
- Navikas
- Nesaretnam
- Norum
- Noseworthy
- Ogawa
- Oliveira
- Olson
- O’Connor
- Packer
- Pekmezci
- Pietta
- PRISMS.
- Pugliatti
- Qu
- Radi
- Reed
- Reed
- Riccio
- Ropper
- Rosenberg
- Rovaris
- Runia
- Salemi
- Salinthone
- Salzer
- Sanoobar
- Sarchielli
- Schmelzer
- Serbinova
- Sheridan
- Shults
- Shults
- Sies
- Singh
- Smith
- Smith
- Smolders
- Somayajulu
- Swank
- Swank
- Syburra
- Tasset
- The IFNB Multiple Sclerosis Study Group
- Tomeo
- Torkildsen
- Torkildsen
- Trapp
- Tully
- US Department of Agriculture and US Department of Health and Human Service
- van der Mei
- van Horssen
- van Meeteren
- Van Vliet
- Warren
- Warren
- Weiner
- Wingerchuk
- Wink
- Witherick
- Witkowska
- Yadav
- Yang
- Young
- Zhang
- Zhang
- Ziegler
- Ziemssen
- Zingg
- Zivadinov
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2015
- Field of study