Morphology of adhesive surfaces in the sisorid catfish, Glyptothorax sinense sikkimensis

This paper deals with the surface morphology and structure of suctorial mouthparts, expanded paired fins and adhesive organ (AO) in a mountain stream catfish Glyptothorax sinense sikkimensis of India, as studied by scanning electron microscopy. It possesses type I taste buds on its barbels and lips. There are scattered unculiferous plaques on the lower lip and horny tubercles on outer fin rays, and knob like microstructures between fin rays of both paired fins. The thoracic region bears a prominent AO, which has 8-10unculiferous ridges arranged parallel to the body axis, separated by many non-unculiferous grooves. The latter may act as the major attachment sites and function as a suction cup. A combined action of the adhesive devices with their unique surface specializations enables the fish for better anchorage to sandy-rocky substratum of glacier-fed, rapid mountain streams. The plaques on lower lip and horny tubercles and knob like substructures in fin rays perhaps help in additional anchorage support to the major AO located at the thoracic area

Mode of accretion in episodic radio galaxies and the dynamics of their outer relic lobes

We present X-ray observations with the X-ray Multi-Mirror Mission Newton (XMM-Newton) telescope of three Double-Double Radio Galaxies (DDRGs). We have detected the core, lobes and the environment of our sample DDRGs in X-rays. We examine the relationships between the radio and X-ray emission and attribute the X-ray emission from the lobes to the inverse-Compton scattering of cosmic microwave background (CMB) photons against the leptons of the radio lobes. The magnetic field strength of the lobes is close to the equipartition value. The X-ray spectrum of the cores of the DDRGs consists of an unabsorbed soft power-law component and no sign of hard power law components. The soft unabsorbed component is likely to be related to the radio jets. In optical wavebands, there is no strong [O III] lines observed and the host galaxies are not detected in all four bands (namely 2.4, 4.6, 12, 22 µm) of Wide-Field Infrared Survey Explorer (WISE) survey. This shows that they are low excitation radio galaxies. These DDRGs have poor group scale ambient media. We discuss the implications of this observation for models of the episodic activity in DDRGs

Mass Outflow Rate From Accretion Discs around Compact Objects

We compute mass outflow rates from accretion disks around compact objects, such as neutron stars and black holes. These computations are done using combinations of exact transonic inflow and outflow solutions which may or may not form standing shock waves. Assuming that the bulk of the outflow is from the effective boundary layers of these objects, we find that the ratio of the outflow rate and inflow rate varies anywhere from a few percent to even close to a hundred percent (i.e., close to disk evacuation case) depending on the initial parameters of the disk, the degree of compression of matter near the centrifugal barrier, and the polytropic index of the flow. Our result, in general, matches with the outflow rates obtained through a fully time-dependent numerical simulation. In some region of the parameter space when the standing shock does not form, our results indicate that the disk may be evacuated and may produce quiescence states.Comment: 30 Latex pages and 13 figures. crckapb.sty; Published in Class. Quantum Grav. Vol. 16. No. 12. Pg. 387

A systematic review to identify areas of enhancements of pandemic simulation models for operational use at provincial and local levels

<p>Abstract</p> <p>Background</p> <p>In recent years, computer simulation models have supported development of pandemic influenza preparedness policies. However, U.S. policymakers have raised several <it>concerns </it>about the practical use of these models. In this review paper, we examine the extent to which the current literature already addresses these <it>concerns </it>and identify means of enhancing the current models for higher operational use.</p> <p>Methods</p> <p>We surveyed PubMed and other sources for published research literature on simulation models for influenza pandemic preparedness. We identified 23 models published between 1990 and 2010 that consider single-region (e.g., country, province, city) outbreaks and multi-pronged mitigation strategies. We developed a plan for examination of the literature based on the concerns raised by the policymakers.</p> <p>Results</p> <p>While examining the concerns about the adequacy and validity of data, we found that though the epidemiological data supporting the models appears to be adequate, it should be validated through as many updates as possible during an outbreak. Demographical data must improve its interfaces for access, retrieval, and translation into model parameters. Regarding the concern about credibility and validity of modeling assumptions, we found that the models often simplify reality to reduce computational burden. Such simplifications may be permissible if they do not interfere with the performance assessment of the mitigation strategies. We also agreed with the concern that social behavior is inadequately represented in pandemic influenza models. Our review showed that the models consider only a few social-behavioral aspects including contact rates, withdrawal from work or school due to symptoms appearance or to care for sick relatives, and compliance to social distancing, vaccination, and antiviral prophylaxis. The concern about the degree of accessibility of the models is palpable, since we found three models that are currently accessible by the public while other models are seeking public accessibility. Policymakers would prefer models scalable to any population size that can be downloadable and operable in personal computers. But scaling models to larger populations would often require computational needs that cannot be handled with personal computers and laptops. As a limitation, we state that some existing models could not be included in our review due to their limited available documentation discussing the choice of relevant parameter values.</p> <p>Conclusions</p> <p>To adequately address the concerns of the policymakers, we need continuing model enhancements in critical areas including: updating of epidemiological data during a pandemic, smooth handling of large demographical databases, incorporation of a broader spectrum of social-behavioral aspects, updating information for contact patterns, adaptation of recent methodologies for collecting human mobility data, and improvement of computational efficiency and accessibility.</p

A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling

<p>Abstract</p> <p>Background</p> <p>High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a standard set of probes measuring the methylation status of CpG sites across the whole genome is that many sites may not show inter-individual methylation variation among the biosamples for the disease outcome being studied. Inclusion of these so-called "non-variable sites" will increase the risk of false discoveries and reduce statistical power to detect biologically relevant methylation markers.</p> <p>Results</p> <p>We propose a method to estimate the proportion of non-variable CpG sites and eliminate those sites from further analyses. Our method is illustrated using data obtained by hybridizing DNA extracted from the peripheral blood mononuclear cells of 311 samples to an array assaying 1505 CpG sites. Results showed that a large proportion of the CpG sites did not show inter-individual variation in methylation.</p> <p>Conclusions</p> <p>Our method resulted in a substantial improvement in association signals between methylation sites and outcome variables while controlling the false discovery rate at the same level.</p

Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good

Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation

One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced. Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI

Search for stop and higgsino production using diphoton Higgs boson decays

Results are presented of a search for a "natural" supersymmetry scenario with gauge mediated symmetry breaking. It is assumed that only the supersymmetric partners of the top-quark (stop) and the Higgs boson (higgsino) are accessible. Events are examined in which there are two photons forming a Higgs boson candidate, and at least two b-quark jets. In 19.7 inverse femtobarns of proton-proton collision data at sqrt(s) = 8 TeV, recorded in the CMS experiment, no evidence of a signal is found and lower limits at the 95% confidence level are set, excluding the stop mass below 360 to 410 GeV, depending on the higgsino mass