598 research outputs found
Eigenvalue computations in the context of data-sparse approximations of integral operators
In this work, we consider the numerical solution of a large eigenvalue problem resulting from a finite rank discretization of an integral operator. We are interested in computing a few eigenpairs, with an iterative method, so a matrix representation that allows for fast matrix-vector products is required. Hierarchical matrices are appropriate for this setting, and also provide cheap LU decompositions required in the spectral transformation technique. We illustrate the use of freely available software tools to address the problem, in particular SLEPc for the eigensolvers and HLib for the construction of H-matrices. The numerical tests are performed using an astrophysics application. Results show the benefits of the data-sparse representation compared to standard storage schemes, in terms of computational cost as well as memory requirements.This work was partially supported by the Spanish Ministerio de Ciencia e Innovacion under projects TIN2009-07519, TIN2012-32846 and AIC10-D-000600 and by Fundacao para a Ciencia e a Tecnologia - FCT under project FCT/MICINN proc 441.00.RomĂĄn MoltĂł, JE.; Vasconcelos, PB.; Nunes, AL. (2013). Eigenvalue computations in the context of data-sparse approximations of integral operators. Journal of Computational and Applied Mathematics. 237(1):171-181. doi:10.1016/j.cam.2012.07.021S171181237
Carbohydrate carbon sources induce loss of flocculation of an ale-brewing yeast strain
Aims: To identify the nutrients that can trigger the loss of flocculation under growth conditions in an ale-brewing strain, Saccharomyces cerevisiae NCYC 1195.
Methods and Results: Flocculation was evaluated using the method of Soares, EX. and Vroman, A. [Journal of Applied Microbiology (2003) 95, 325]. Yeast growth with metabolizable carbon sources (glucose, fructose, galactose, maltose or sucrose) at 2% (w/v), induced the loss of flocculation in yeast that had previously been allowed to flocculate. The yeast remained flocculent when transferred to a medium containing the required nutrients for yeast growth and a sole nonmetabolizable carbon source (lactose). Transfer of flocculent yeast into a growth medium with ethanol (4% v/v), as the sole carbon source did not induce the loss of flocculation. Even the addition of glucose (2% w/v) or glucose and antimycin A (0.1 mg lËÂč) to this culture did not bring about loss of flocculation. Cycloheximide addition (15 mglËÂč) to glucose-growing cells stopped flocculation loss.
Conclusions: Carbohydrates were the nutrients responsible for stimulating the loss of flocculation in flocculent yeast cells transferred to growing conditions. The glucose-induced loss of flocculation required de novo protein synthesis. Ethanol prevented glucose-induced loss of flocculation. This protective effect of ethanol was independent of the respiratory function of the yeast.
Significance and Impact of the Study: This work contributes to the elucidation of the role of nutrients in the control of the flocculation cycle in NewFlo phenotype yeast strains.Instituto Politécnico do Porto (IPP) - Fundo de Apoio à Investigação - Project P24/96 , P24/97.Programa Plurianual de Unidades de I&D-CIEA/
ISEP
Flocculation onset in Saccharomyces cerevisiae: effect of ethanol, heat and osmotic stress
Aims: To examine the effect of different stress conditions on the onset of flocculation
in an ale-brewing strain, Saccharomyces cerevisiae NCYC 1195.
Methods and Results: Flocculation was evaluated using the method of Soares,
E.V. and Vroman, A. [Journal of Applied Microbiology (2003) 95, 325]; plasma
membrane integrity was accessed using propidium iodide and the staining of
the yeast cell wall was performed using calcofluor white M2R. Cells in exponential
phase of growth were subjected to different stress conditions. The addition
of 1%, 3% and 5% (v/v) ethanol, 1% and 3% (v/v) isopropanol or a brief heat shock (52ÂșC, 5 min), did not induce an early flocculation phenotype when compared with control cells. The addition of 10% (v/v) ethanol, a continuous mild heat-stress (37ÂșC) or an osmotic stress (0.5 or 1 mol l-1 of NaCl) did not induce a flocculent phenotype.
Conclusions: Flocculation seems not to be induced as a response to different
chemical (ethanol and isopropanol) and physical (heat and osmotic) stress conditions.
Conversely, osmotic and ethanol [10% (v/v)] stress, as well as a continuous mild heat shock (37ÂșC), have a negative impact on the phenotype expression of flocculation.
Significance and Impact of the Study: The findings reported here contribute to
the elucidation of the control of yeast flocculation. This information might be
useful to the brewing industry, as the time when the onset of flocculation
occurs can determine the fermentation performance and the beer quality, as
well as in other biotechnological industries where flocculation can be used as a
cell separation process.ERASMUS; ISEP (Portugal)
Transport properties of strongly correlated metals:a dynamical mean-field approach
The temperature dependence of the transport properties of the metallic phase
of a frustrated Hubbard model on the hypercubic lattice at half-filling are
calculated. Dynamical mean-field theory, which maps the Hubbard model onto a
single impurity Anderson model that is solved self-consistently, and becomes
exact in the limit of large dimensionality, is used. As the temperature
increases there is a smooth crossover from coherent Fermi liquid excitations at
low temperatures to incoherent excitations at high temperatures. This crossover
leads to a non-monotonic temperature dependence for the resistance,
thermopower, and Hall coefficient, unlike in conventional metals. The
resistance smoothly increases from a quadratic temperature dependence at low
temperatures to large values which can exceed the Mott-Ioffe-Regel value, hbar
a/e^2 (where "a" is a lattice constant) associated with mean-free paths less
than a lattice constant. Further signatures of the thermal destruction of
quasiparticle excitations are a peak in the thermopower and the absence of a
Drude peak in the optical conductivity. The results presented here are relevant
to a wide range of strongly correlated metals, including transition metal
oxides, strontium ruthenates, and organic metals.Comment: 19 pages, 9 eps figure
Weak magnetism and non-Fermi liquids near heavy-fermion critical points
This paper is concerned with the weak-moment magnetism in heavy-fermion
materials and its relation to the non-Fermi liquid physics observed near the
transition to the Fermi liquid. We explore the hypothesis that the primary
fluctuations responsible for the non-Fermi liquid physics are those associated
with the destruction of the large Fermi surface of the Fermi liquid. Magnetism
is suggested to be a low-energy instability of the resulting small Fermi
surface state. A concrete realization of this picture is provided by a
fractionalized Fermi liquid state which has a small Fermi surface of conduction
electrons, but also has other exotic excitations with interactions described by
a gauge theory in its deconfined phase. Of particular interest is a
three-dimensional fractionalized Fermi liquid with a spinon Fermi surface and a
U(1) gauge structure. A direct second-order transition from this state to the
conventional Fermi liquid is possible and involves a jump in the electron Fermi
surface volume. The critical point displays non-Fermi liquid behavior. A
magnetic phase may develop from a spin density wave instability of the spinon
Fermi surface. This exotic magnetic metal may have a weak ordered moment
although the local moments do not participate in the Fermi surface.
Experimental signatures of this phase and implications for heavy-fermion
systems are discussed.Comment: 20 pages, 8 figures; (v2) includes expanded discussion and solution
of quantum Boltzmann equatio
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Risk Owners & Risk Managers: Dealing with the complexity of feeding children with neurodevelopmental disability
This paper illustrates negotiations around risk between lay people and clinicians in relation to gastrostomy interventions for disabled children. These negotiations centre on differing interpretations of what constitutes risk in relation to the safety of oral feeding and a child's need for a feeding tube between parents, carers and clinical specialties. Drawing on Heyman's distinction between risk managers and risk owners, we show that not only do clinicians act as risk managers and parents and carers as risk owners, but that these distinctions often become blurred either because of the shifting dynamics of relations of care or because of the specificity of clinical practice. Parents become risk managers in relation to carers' roles, while clinicians become risk owners in relation to particular procedures which define their practice. This has implications for lay and expert interactions as well as professional accountability for those caring for children with complex medical conditions. Although not an empirical article, we draw on empirical work in the UK. We analyse both parental and professional constructions of risk based on observations of co-ordinating a clinical trial designed to evaluate the effectiveness of gastrostomy surgery. We also examine the diverse value systems used by different groups of professionals and lay carers which inform judgements about risk and feeding. We conclude by arguing that issues of risk in contemporary health care are not just examples of âmanufactured uncertaintyâ or of ânegotiated powerâ but constitute a dialectical relationship which breaks down the essentialist dualism of lay and professional constructions of risk
A green-gray path to global water security and sustainable infrastructure
Sustainable development demands reliable water resources, yet traditional water management has broadly failed to avoid environmental degradation and contain infrastructure costs. We explore the global-scale feasibility of combining natural capital with engineering-based (green-gray) approaches to meet water security threats over the 21st century. Threats to water resource systems are projected to rise throughout this period, together with a significant expansion in engineering deployments and progressive loss of natural capital. In many parts of the world, strong path dependencies are projected to arise from the legacy of prior environmental degradation that constrains future water management to a heavy reliance on engineering-based approaches. Elsewhere, retaining existing stocks of natural capital creates opportunities to employ blended green-gray water infrastructure. By 2050, annual engineering expenditures are projected to triple to 3.0 trillion in avoided replacement costs by mid-century. Society pays a premium whenever these nature-based assets are lost, as the engineering costs necessary to achieve an equivalent level of threat management are, on average, twice as expensive. Countries projected to rapidly expand their engineering investments while losing natural capital will be most constrained in realizing green-gray water management. The situation is expected to be most restrictive across the developing world, where the economic, technical, and governance capacities to overcome such challenges remain limited. Our results demonstrate that policies that support blended green-gray approaches offer a pathway to future global water security but will require a strategic commitment to preserving natural capital. Absent such stewardship, the costs of water resource infrastructure and services will likely rise substantially and frustrate efforts to attain universal and sustainable water security
Subleading-twist effects in single-spin asymmetries in semi-inclusive deep-inelastic scattering on a longitudinally polarized hydrogen target
Single-spin asymmetries in the semi-inclusive production of charged pions in
deep-inelastic scattering from transversely and longitudinally polarized proton
targets are combined to evaluate the subleading-twist contribution to the
longitudinal case. This contribution is significantly positive for (\pi^+)
mesons and dominates the asymmetries on a longitudinally polarized target
previously measured by \hermes. The subleading-twist contribution for (\pi^-)
mesons is found to be small
Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment
This paper describes an analysis of the angular distribution of W->enu and
W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with
the ATLAS detector at the LHC in 2010, corresponding to an integrated
luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and
the missing transverse energy, the W decay angular distribution projected onto
the transverse plane is obtained and analysed in terms of helicity fractions
f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV
and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw
> 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour,
are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017
+/- 0.030, where the first uncertainties are statistical, and the second
include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables,
revised author list, matches European Journal of Physics C versio
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